Q9LFH0
PR
Gene name |
ABCG37 |
Protein name |
ABC transporter G family member 37 |
Names |
ABC transporter ABCG.37, AtABCG37, Pleiotropic drug resistance protein 9, Protein ENHANCER OF TIR1-1 AUXIN RESISTANCE 4, Protein POLAR AUXIN TRANSPORT INHIBITOR SENSITIVE 1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G53480 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LFH0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LFH0-F1 | Predicted | AlphaFoldDB |
54 variants for Q9LFH0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_19825373_A_C | 3 | H>P | No | 1000Genomes | |
| ENSVATH02500121 | 33 | S>T | No | 1000Genomes | |
| tmp_3_19825495_G_A | 44 | V>I | No | 1000Genomes | |
| tmp_3_19825566_A_C | 67 | L>F | No | 1000Genomes | |
| ENSVATH00417474 | 70 | V>I | No | 1000Genomes | |
| tmp_3_19825621_A_G | 86 | T>A | No | 1000Genomes | |
| ENSVATH02500122 | 91 | R>K | No | 1000Genomes | |
| ENSVATH02500123 | 101 | V>M | No | 1000Genomes | |
| tmp_3_19825704_C_A | 113 | H>Q | No | 1000Genomes | |
| ENSVATH00417475 | 114 | I>L | No | 1000Genomes | |
| tmp_3_19825720_C_T | 119 | L>F | No | 1000Genomes | |
| ENSVATH00417477 | 145 | S>G | Yellowing is a precocious more diffused leaf chlorosis. accessions were divided in three subgroups (mild-intermediate-severe) according to the severity of the yellowing. [23c and 8hrs daylight for 7 weeks] [EnsemblGenome] | No | 1000Genomes |
| ENSVATH06308331 | 151 | E>K | No | 1000Genomes | |
| ENSVATH02500129 | 182 | T>P | No | 1000Genomes | |
| tmp_3_19826082_A_G | 183 | H>R | No | 1000Genomes | |
| tmp_3_19826105_A_G | 191 | N>D | No | 1000Genomes | |
| tmp_3_19826123_A_G | 197 | I>V | No | 1000Genomes | |
| tmp_3_19826127_A_T | 198 | K>M | No | 1000Genomes | |
| tmp_3_19826504_G_A | 263 | M>I | No | 1000Genomes | |
| tmp_3_19826508_G_A | 265 | V>M | No | 1000Genomes | |
| ENSVATH00417487 | 330 | L>I | No | 1000Genomes | |
| tmp_3_19827315_A_C | 418 | M>L | No | 1000Genomes | |
| tmp_3_19827339_G_A | 426 | V>M | No | 1000Genomes | |
| ENSVATH00417490 | 432 | G>R | No | 1000Genomes | |
| ENSVATH02500144 | 472 | D>N | No | 1000Genomes | |
| ENSVATH06308349 | 481 | E>Q | No | 1000Genomes | |
| tmp_3_19827716_C_A | 522 | P>Q | No | 1000Genomes | |
| ENSVATH00417492 | 550 | A>V | No | 1000Genomes | |
| tmp_3_19828000_A_G | 587 | I>V | No | 1000Genomes | |
| ENSVATH02500146 | 667 | V>I | No | 1000Genomes | |
| tmp_3_19828367_A_C | 681 | I>L | No | 1000Genomes | |
| tmp_3_19828442_G_A | 706 | V>I | No | 1000Genomes | |
| tmp_3_19828744_G_A | 745 | M>I | No | 1000Genomes | |
| tmp_3_19828757_T_G | 750 | F>V | No | 1000Genomes | |
| tmp_3_19828800_A_G | 764 | Y>C | No | 1000Genomes | |
| tmp_3_19829054_CAACAGAA_C,TAACAGAA | 818 | S>L | No | 1000Genomes | |
| ENSVATH00417494 | 858 | F>L | No | 1000Genomes | |
| ENSVATH12744053 | 921 | I>T | No | 1000Genomes | |
| ENSVATH06308360 | 970 | A>S | No | 1000Genomes | |
| ENSVATH12744055 | 981 | L>I | No | 1000Genomes | |
| tmp_3_19829820_G_C | 991 | D>H | No | 1000Genomes | |
| ENSVATH14429360 | 998 | G>V | No | 1000Genomes | |
| tmp_3_19830185_G_A | 1081 | M>I | No | 1000Genomes | |
| ENSVATH12744063 | 1092 | R>H | No | 1000Genomes | |
| ENSVATH12744064 | 1098 | F>Y | No | 1000Genomes | |
| ENSVATH14429362 | 1100 | S>I | No | 1000Genomes | |
| ENSVATH12744085 | 1130 | G>D | No | 1000Genomes | |
| ENSVATH14429363 | 1175 | G>R | No | 1000Genomes | |
| tmp_3_19830986_G_T | 1263 | R>I | No | 1000Genomes | |
| ENSVATH00417498 | 1269 | S>A | No | 1000Genomes | |
| ENSVATH14429395 | 1290 | A>T | No | 1000Genomes | |
| ENSVATH02500167 | 1306 | A>T | No | 1000Genomes | |
| tmp_3_19831180_A_T | 1328 | M>L | No | 1000Genomes | |
| ENSVATH00417500 | 1401 | Q>E | No | 1000Genomes |
No associated diseases with Q9LFH0
1 regional properties for Q9LFH0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | von Willebrand factor, type A | 319 - 483 | IPR002035 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| plasmodesma | A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ABC-type transporter activity | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| auxin efflux transmembrane transporter activity | Enables the transfer of auxin, from one side of a membrane to the other, out of a cell. |
| efflux transmembrane transporter activity | Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane. |
11 GO annotations of biological process
| Name | Definition |
|---|---|
| 2,4-dichlorophenoxyacetic acid metabolic process | The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds. |
| auxin homeostasis | A homeostatic process that maintains an endogenous steady-state concentration of primary auxin, or constant level of auxin in a biological system, by a number of biochemical processes including transport, biosynthesis, catabolism and conjugation. |
| auxin polar transport | The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally. |
| auxin-activated signaling pathway | The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription. |
| cellular detoxification | Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. |
| cellular response to indolebutyric acid stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus. |
| coumarin metabolic process | The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids. |
| export from cell | The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis. |
| response to iron ion starvation | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of iron ion. |
| root development | The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo. |
| transmembrane transport | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
14 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q08409 | AUS1 | ATP-dependent permease AUS1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P40550 | PDR11 | ATP-dependent permease PDR11 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q8GU92 | ABCG35 | ABC transporter G family member 35 | Oryza sativa subsp japonica (Rice) | PR |
| Q8GU83 | ABCG41 | ABC transporter G family member 41 | Oryza sativa subsp japonica (Rice) | PR |
| Q9M2V6 | ABCG17 | ABC transporter G family member 17 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O81016 | ABCG32 | ABC transporter G family member 32 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC81 | ABCG43 | ABC transporter G family member 43 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC83 | ABCG41 | ABC transporter G family member 41 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZUT8 | ABCG33 | ABC transporter G family member 33 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9MAH4 | ABCG10 | ABC transporter G family member 10 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9MAG3 | ABCG24 | ABC transporter G family member 24 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SZR9 | ABCG9 | ABC transporter G family member 9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GZ52 | ABCG30 | ABC transporter G family member 30 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC82 | ABCG42 | ABC transporter G family member 42 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAHMVGADDI | ESLRVELAEI | GRSIRSSFRR | HTSSFRSSSS | IYEVENDGDV | NDHDAEYALQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WAEIERLPTV | KRMRSTLLDD | GDESMTEKGR | RVVDVTKLGA | VERHLMIEKL | IKHIENDNLK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LLKKIRRRID | RVGMELPTIE | VRYESLKVVA | ECEVVEGKAL | PTLWNTAKRV | LSELVKLTGA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KTHEAKINII | NDVNGIIKPG | RLTLLLGPPS | CGKTTLLKAL | SGNLENNLKC | SGEISYNGHR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LDEFVPQKTS | AYISQYDLHI | AEMTVRETVD | FSARCQGVGS | RTDIMMEVSK | REKEKGIIPD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TEVDAYMKAI | SVEGLQRSLQ | TDYILKILGL | DICAEILIGD | VMRRGISGGQ | KKRLTTAEMI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VGPTKALFMD | EITNGLDSST | AFQIVKSLQQ | FAHISSATVL | VSLLQPAPES | YDLFDDIMLM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| AKGRIVYHGP | RGEVLNFFED | CGFRCPERKG | VADFLQEVIS | KKDQAQYWWH | EDLPYSFVSV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EMLSKKFKDL | SIGKKIEDTL | SKPYDRSKSH | KDALSFSVYS | LPNWELFIAC | ISREYLLMKR |
| 550 | 560 | 570 | 580 | 590 | 600 |
| NYFVYIFKTA | QLVMAAFITM | TVFIRTRMGI | DIIHGNSYMS | ALFFALIILL | VDGFPELSMT |
| 610 | 620 | 630 | 640 | 650 | 660 |
| AQRLAVFYKQ | KQLCFYPAWA | YAIPATVLKV | PLSFFESLVW | TCLSYYVIGY | TPEASRFFKQ |
| 670 | 680 | 690 | 700 | 710 | 720 |
| FILLFAVHFT | SISMFRCLAA | IFQTVVASIT | AGSFGILFTF | VFAGFVIPPP | SMPAWLKWGF |
| 730 | 740 | 750 | 760 | 770 | 780 |
| WANPLSYGEI | GLSVNEFLAP | RWNQMQPNNF | TLGRTILQTR | GMDYNGYMYW | VSLCALLGFT |
| 790 | 800 | 810 | 820 | 830 | 840 |
| VLFNIIFTLA | LTFLKSPTSS | RAMISQDKLS | ELQGTEKSTE | DSSVRKKTTD | SPVKTEEEDK |
| 850 | 860 | 870 | 880 | 890 | 900 |
| MVLPFKPLTV | TFQDLNYFVD | MPVEMRDQGY | DQKKLQLLSD | ITGAFRPGIL | TALMGVSGAG |
| 910 | 920 | 930 | 940 | 950 | 960 |
| KTTLLDVLAG | RKTSGYIEGD | IRISGFPKVQ | ETFARVSGYC | EQTDIHSPNI | TVEESVIYSA |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| WLRLAPEIDA | TTKTKFVKQV | LETIELDEIK | DSLVGVTGVS | GLSTEQRKRL | TIAVELVANP |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| SIIFMDEPTT | GLDARAAAIV | MRAVKNVADT | GRTIVCTIHQ | PSIDIFEAFD | ELVLLKRGGR |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| MIYTGPLGQH | SRHIIEYFES | VPEIPKIKDN | HNPATWMLDV | SSQSVEIELG | VDFAKIYHDS |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| ALYKRNSELV | KQLSQPDSGS | SDIQFKRTFA | QSWWGQFKSI | LWKMNLSYWR | SPSYNLMRMM |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| HTLVSSLIFG | ALFWKQGQNL | DTQQSMFTVF | GAIYGLVLFL | GINNCASALQ | YFETERNVMY |
| 1270 | 1280 | 1290 | 1300 | 1310 | 1320 |
| RERFAGMYSA | TAYALGQVVT | EIPYIFIQAA | EFVIVTYPMI | GFYPSAYKVF | WSLYSMFCSL |
| 1330 | 1340 | 1350 | 1360 | 1370 | 1380 |
| LTFNYLAMFL | VSITPNFMVA | AILQSLFYVG | FNLFSGFLIP | QTQVPGWWIW | LYYLTPTSWT |
| 1390 | 1400 | 1410 | 1420 | 1430 | 1440 |
| LNGFISSQYG | DIHEEINVFG | QSTTVARFLK | DYFGFHHDLL | AVTAVVQIAF | PIALASMFAF |
| FVGKLNFQRR |