O81016
PR
Gene name |
ABCG32 |
Protein name |
ABC transporter G family member 32 |
Names |
ABC transporter ABCG.32, AtABCG32, Pleiotropic drug resistance protein 4, Protein PERMEABLE CUTICLE 1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G26910 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O81016
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O81016-F1 | Predicted | AlphaFoldDB |
37 variants for O81016
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH05601292 | 11 | R>L | No | 1000Genomes | |
| ENSVATH05601293 | 13 | T>A | No | 1000Genomes | |
| tmp_2_11482186_G_T | 133 | G>V | No | 1000Genomes | |
| tmp_2_11482529_A_G | 191 | T>A | No | 1000Genomes | |
| tmp_2_11482541_A_C | 195 | I>L | No | 1000Genomes | |
| tmp_2_11482574_A_C | 206 | I>L | No | 1000Genomes | |
| ENSVATH13422875 | 212 | A>T | No | 1000Genomes | |
| ENSVATH05601306 | 234 | G>A | No | 1000Genomes | |
| ENSVATH13422880 | 325 | A>V | No | 1000Genomes | |
| tmp_2_11483462_C_A | 359 | T>N | No | 1000Genomes | |
| ENSVATH13422882 | 393 | D>N | No | 1000Genomes | |
| ENSVATH05601327 | 408 | D>E | No | 1000Genomes | |
| tmp_2_11483720_G_C | 419 | V>L | No | 1000Genomes | |
| tmp_2_11483814_C_T | 450 | S>L | No | 1000Genomes | |
| ENSVATH14557765 | 458 | A>T | No | 1000Genomes | |
| tmp_2_11484516_C_A | 625 | L>M | No | 1000Genomes | |
| ENSVATH13422890 | 722 | K>R | No | 1000Genomes | |
| tmp_2_11485085_C_A | 757 | H>Q | No | 1000Genomes | |
| ENSVATH05601380 | 882 | G>E | No | 1000Genomes | |
| tmp_2_11485816_G_A | 920 | V>I | No | 1000Genomes | |
| tmp_2_11486018_G_A | 959 | G>E | No | 1000Genomes | |
| ENSVATH13422906 | 1041 | L>M | No | 1000Genomes | |
| ENSVATH14557770 | 1077 | P>L | No | 1000Genomes | |
| ENSVATH05601392 | 1092 | T>A | No | 1000Genomes | |
| ENSVATH13422909 | 1093 | E>K | No | 1000Genomes | |
| tmp_2_11486580_C_T | 1095 | H>Y | No | 1000Genomes | |
| ENSVATH05601393 | 1096 | R>W | No | 1000Genomes | |
| ENSVATH01903476 | 1107 | N>S | No | 1000Genomes | |
| tmp_2_11486625_C_G | 1110 | L>V | No | 1000Genomes | |
| ENSVATH05601397 | 1113 | R>C | No | 1000Genomes | |
| tmp_2_11486739_A_G | 1118 | I>V | No | 1000Genomes | |
| ENSVATH05601403 | 1195 | F>S | No | 1000Genomes | |
| ENSVATH05601403 | 1195 | F>Y | No | 1000Genomes | |
| tmp_2_11487182_C_A | 1240 | P>T | No | 1000Genomes | |
| tmp_2_11487711_C_T | 1367 | S>L | No | 1000Genomes | |
| tmp_2_11487809_T_G | 1400 | F>V | No | 1000Genomes | |
| tmp_2_11487815_G_A | 1402 | V>I | No | 1000Genomes |
No associated diseases with O81016
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| peroxisome | A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ABC-type transporter activity | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cutin transport | The directed movement of cutin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cutin, which consists of C16-18 fatty acids, is the major component of the cuticle that covers the plant surface. |
13 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q08409 | AUS1 | ATP-dependent permease AUS1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P40550 | PDR11 | ATP-dependent permease PDR11 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q8GU92 | ABCG35 | ABC transporter G family member 35 | Oryza sativa subsp japonica (Rice) | PR |
| Q9M2V6 | ABCG17 | ABC transporter G family member 17 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC81 | ABCG43 | ABC transporter G family member 43 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC83 | ABCG41 | ABC transporter G family member 41 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LFH0 | ABCG37 | ABC transporter G family member 37 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZUT8 | ABCG33 | ABC transporter G family member 33 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9MAH4 | ABCG10 | ABC transporter G family member 10 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9MAG3 | ABCG24 | ABC transporter G family member 24 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SZR9 | ABCG9 | ABC transporter G family member 9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GZ52 | ABCG30 | ABC transporter G family member 30 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC82 | ABCG42 | ABC transporter G family member 42 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MWNSAENAFS | RSTSFKDEIE | DEEELRWAAL | QRLPTYSRIR | RGIFRDMVGE | PKEIQIGNLE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ASEQRLLLDR | LVNSVENDPE | QFFARVRKRF | DAVDLKFPKI | EVRFQNLMVE | SFVHVGSRAL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PTIPNFIINM | AEGLLRNIHV | IGGKRNKLTI | LDGISGVIRP | SRLTLLLGPP | SSGKTTLLLA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LAGRLGTNLQ | TSGKITYNGY | DLKEIIAPRT | SAYVSQQDWH | VAEMTVRQTL | EFAGRCQGVG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FKYDMLLELA | RREKLAGIVP | DEDLDIFMKS | LALGGMETSL | VVEYVMKILG | LDTCADTLVG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DEMIKGISGG | QKKRLTTGEL | LVGPARVLFM | DEISNGLDSS | TTHQIIMYMR | HSTHALEGTT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VISLLQPSPE | TYELFDDVIL | MSEGQIIYQG | PRDEVLDFFS | SLGFTCPDRK | NVADFLQEVT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SKKDQQQYWS | VPFRPYRYVP | PGKFAEAFRS | YPTGKKLAKK | LEVPFDKRFN | HSAALSTSQY |
| 490 | 500 | 510 | 520 | 530 | 540 |
| GVKKSELLKI | NFAWQKQLMK | QNAFIYVFKF | VQLLLVALIT | MTVFCRTTMH | HNTIDDGNIY |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LGSLYFSMVI | ILFNGFTEVP | MLVAKLPVLY | KHRDLHFYPS | WAYTLPSWLL | SIPTSIIESA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TWVAVTYYTI | GYDPLFSRFL | QQFLLYFSLH | QMSLGLFRVM | GSLGRHMIVA | NTFGSFAMLV |
| 670 | 680 | 690 | 700 | 710 | 720 |
| VMTLGGFIIS | RDSIPSWWIW | GYWISPLMYA | QNAASVNEFL | GHNWQKTAGN | HTSDSLGLAL |
| 730 | 740 | 750 | 760 | 770 | 780 |
| LKERSLFSGN | YWYWIGVAAL | LGYTVLFNIL | FTLFLAHLNP | WGKFQAVVSR | EELDEREKKR |
| 790 | 800 | 810 | 820 | 830 | 840 |
| KGDEFVVELR | EYLQHSGSIH | GKYFKNRGMV | LPFQPLSLSF | SNINYYVDVP | LGLKEQGILE |
| 850 | 860 | 870 | 880 | 890 | 900 |
| DRLQLLVNIT | GAFRPGVLTA | LVGVSGAGKT | TLMDVLAGRK | TGGTIEGDVY | ISGFPKRQET |
| 910 | 920 | 930 | 940 | 950 | 960 |
| FARISGYCEQ | NDVHSPCLTV | VESLLFSACL | RLPADIDSET | QRAFVHEVME | LVELTSLSGA |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| LVGLPGVDGL | STEQRKRLTI | AVELVANPSI | VFMDEPTSGL | DARAAAIVMR | TVRNIVNTGR |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| TIVCTIHQPS | IDIFESFDEL | LFMKRGGELI | YAGPLGQKSC | ELIKYFESIE | GVQKIKPGHN |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| PAAWMLDVTA | STEEHRLGVD | FAEIYRNSNL | CQRNKELIEV | LSKPSNIAKE | IEFPTRYSQS |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| LYSQFVACLW | KQNLSYWRNP | QYTAVRFFYT | VVISLMLGTI | CWKFGSKRDT | QQQLFNAMGS |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| MYAAVLFIGI | TNATAAQPVV | SIERFVSYRE | RAAGMYSALP | FAFAQVFIEF | PYVLAQSTIY |
| 1270 | 1280 | 1290 | 1300 | 1310 | 1320 |
| STIFYAMAAF | EWSAVKFLWY | LFFMYFSIMY | FTFYGMMTTA | ITPNHNVASI | IAAPFYMLWN |
| 1330 | 1340 | 1350 | 1360 | 1370 | 1380 |
| LFSGFMIPYK | RIPLWWRWYY | WANPVAWTLY | GLLVSQYGDD | ERSVKLSDGI | HQVMVKQLLE |
| 1390 | 1400 | 1410 | |||
| DVMGYKHDFL | GVSAIMVVAF | CVFFSLVFAF | AIKAFNFQRR |