Q9ZUT8
PR
Gene name |
ABCG33 (PDR5, At2g37280, F3G5.7) |
Protein name |
ABC transporter G family member 33 |
Names |
ABC transporter ABCG.33, AtABCG33, Pleiotropic drug resistance protein 5 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G37280 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9ZUT8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9ZUT8-F1 | Predicted | AlphaFoldDB |
110 variants for Q9ZUT8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_2_15650406_T_G | 3 | S>A | No | 1000Genomes | |
| ENSVATH05670630 | 21 | A>T | No | 1000Genomes | |
| ENSVATH05670631 | 33 | L>F | No | 1000Genomes | |
| tmp_2_15650512_G_A | 38 | R>Q | No | 1000Genomes | |
| tmp_2_15650526_C_G | 43 | L>V | No | 1000Genomes | |
| ENSVATH13559557 | 60 | V>A | No | 1000Genomes | |
| ENSVATH05670632 | 63 | L>F | No | 1000Genomes | |
| ENSVATH05670633 | 85 | K>N | No | 1000Genomes | |
| ENSVATH00263134 | 103 | S>R | No | 1000Genomes | |
| tmp_2_15650801_A_C | 111 | L>F | No | 1000Genomes | |
| ENSVATH05670638 | 153 | K>N | No | 1000Genomes | |
| ENSVATH05670639 | 154 | I>L | No | 1000Genomes | |
| tmp_2_15651032_T_C | 162 | I>T | No | 1000Genomes | |
| tmp_2_15651037_C_T | 164 | P>S | No | 1000Genomes | |
| ENSVATH01959682 | 173 | P>S | No | 1000Genomes | |
| ENSVATH05670640 | 182 | L>I | No | 1000Genomes | |
| tmp_2_15651330_G_A | 210 | V>I | No | 1000Genomes | |
| ENSVATH05670643 | 214 | T>A | No | 1000Genomes | |
| ENSVATH13559560 | 215 | S>L | No | 1000Genomes | |
| tmp_2_15651438_C_G | 246 | R>G | No | 1000Genomes | |
| tmp_2_15651532_T_G | 249 | I>S | No | 1000Genomes | |
| ENSVATH05670647 | 251 | M>T | No | 1000Genomes | |
| ENSVATH01959684 | 252 | E>A | No | 1000Genomes | |
| tmp_2_15651701_A_C | 278 | K>Q | No | 1000Genomes | |
| ENSVATH00263137 | 278 | K>R | No | 1000Genomes | |
| ENSVATH01959685 | 281 | K>Q | No | 1000Genomes | |
| ENSVATH14592763 | 296 | D>G | No | 1000Genomes | |
| tmp_2_15651845_C_A | 299 | A>E | No | 1000Genomes | |
| tmp_2_15651844_G_A | 299 | A>T | No | 1000Genomes | |
| tmp_2_15652096_T_A | 356 | V>E | No | 1000Genomes | |
| ENSVATH14592764 | 366 | V>A | No | 1000Genomes | |
| tmp_2_15652131_C_T | 368 | L>F | No | 1000Genomes | |
| ENSVATH14592765 | 371 | P>S | No | 1000Genomes | |
| tmp_2_15652190_A_C | 387 | E>D | No | 1000Genomes | |
| ENSVATH00263138 | 396 | R>C | No | 1000Genomes | |
| tmp_2_15652222_A_G | 398 | D>G | No | 1000Genomes | |
| tmp_2_15652242_G_A | 405 | E>K | No | 1000Genomes | |
| tmp_2_15652272_G_A | 415 | G>S | No | 1000Genomes | |
| ENSVATH05670656 | 435 | H>Y | No | 1000Genomes | |
| tmp_2_15652472_C_A | 454 | D>E | No | 1000Genomes | |
| tmp_2_15652503_C_T | 465 | L>F | No | 1000Genomes | |
| ENSVATH05670658 | 483 | V>A | No | 1000Genomes | |
| tmp_2_15652576_G_C | 489 | W>S | No | 1000Genomes | |
| tmp_2_15652584_T_C | 492 | F>L | No | 1000Genomes | |
| ENSVATH00263142 | 514 | T>S | No | 1000Genomes | |
| ENSVATH00263143 | 519 | L>I | No | 1000Genomes | |
| tmp_2_15652749_C_T | 521 | A>V | No | 1000Genomes | |
| ENSVATH01959688 | 525 | M>V | No | 1000Genomes | |
| tmp_2_15652801_T_G | 538 | I>M | No | 1000Genomes | |
| ENSVATH05670662 | 545 | S>N | No | 1000Genomes | |
| tmp_2_15652868_G_A | 561 | E>K | No | 1000Genomes | |
| ENSVATH00263144 | 616 | T>S | No | 1000Genomes | |
| ENSVATH14592768 | 644 | A>T | No | 1000Genomes | |
| tmp_2_15653205_A_T | 646 | I>F | No | 1000Genomes | |
| tmp_2_15653396_G_T | 684 | G>W | No | 1000Genomes | |
| tmp_2_15653403_G_C | 686 | W>S | No | 1000Genomes | |
| tmp_2_15653439_C_T | 698 | S>F | No | 1000Genomes | |
| ENSVATH05670667 | 720 | T>I | No | 1000Genomes | |
| ENSVATH05670668 | 731 | D>N | No | 1000Genomes | |
| tmp_2_15653635_A_T | 732 | Y>F | No | 1000Genomes | |
| tmp_2_15653689_C_T | 750 | T>I | No | 1000Genomes | |
| ENSVATH01959695 | 782 | D>A | No | 1000Genomes | |
| tmp_2_15653879_C_A | 788 | N>K | No | 1000Genomes | |
| ENSVATH13559566 | 795 | I>T | No | 1000Genomes | |
| ENSVATH01959698 | 819 | N>K | No | 1000Genomes | |
| tmp_2_15654071_G_T | 824 | V>F | No | 1000Genomes | |
| tmp_2_15654171_G_C | 830 | G>A | No | 1000Genomes | |
| tmp_2_15654174_A_T | 831 | Q>L | No | 1000Genomes | |
| tmp_2_15654198_A_G | 839 | Q>R | No | 1000Genomes | |
| ENSVATH00263145 | 843 | E>D | No | 1000Genomes | |
| tmp_2_15654253_G_A | 857 | M>I | No | 1000Genomes | |
| tmp_2_15654264_G_C | 861 | G>A | No | 1000Genomes | |
| ENSVATH05670674 | 868 | L>I | No | 1000Genomes | |
| ENSVATH00263146 | 879 | Y>C | No | 1000Genomes | |
| ENSVATH05670676 | 890 | L>R | No | 1000Genomes | |
| ENSVATH01959700 | 912 | S>N | No | 1000Genomes | |
| ENSVATH01959701 | 919 | L>I | No | 1000Genomes | |
| tmp_2_15654480_C_G | 933 | P>R | No | 1000Genomes | |
| ENSVATH14592771 | 946 | T>I | No | 1000Genomes | |
| ENSVATH05670681 | 951 | E>G | No | 1000Genomes | |
| ENSVATH14592772 | 955 | A>V | No | 1000Genomes | |
| tmp_2_15654792_G_A | 1011 | A>T | No | 1000Genomes | |
| tmp_2_15654975_T_C | 1044 | M>T | No | 1000Genomes | |
| tmp_2_15655000_A_T | 1052 | Q>H | No | 1000Genomes | |
| ENSVATH05670684 | 1058 | I>V | No | 1000Genomes | |
| ENSVATH05670687 | 1072 | D>G | No | 1000Genomes | |
| tmp_2_15655175_G_A | 1082 | E>K | No | 1000Genomes | |
| ENSVATH00263150 | 1097 | A>S | No | 1000Genomes | |
| ENSVATH13559571 | 1113 | V>L | No | 1000Genomes | |
| ENSVATH05670690 | 1114 | K>E | No | 1000Genomes | |
| ENSVATH05670691 | 1136 | W>L | No | 1000Genomes | |
| ENSVATH01959705 | 1153 | R>K | No | 1000Genomes | |
| tmp_2_15655537_C_G | 1174 | L>V | No | 1000Genomes | |
| tmp_2_15655712_A_C | 1207 | N>T | No | 1000Genomes | |
| ENSVATH05670695 | 1219 | R>G | No | 1000Genomes | |
| tmp_2_15655787_C_T | 1232 | S>F | No | 1000Genomes | |
| tmp_2_15655798_T_G | 1236 | Y>D | No | 1000Genomes | |
| tmp_2_15655878_G_T | 1262 | M>I | No | 1000Genomes | |
| tmp_2_15655990_T_A | 1300 | F>I | No | 1000Genomes | |
| ENSVATH13559572 | 1302 | V>L | No | 1000Genomes | |
| ENSVATH01959706 | 1322 | I>T | No | 1000Genomes | |
| tmp_2_15656151_C_A | 1326 | Q>K | No | 1000Genomes | |
| ENSVATH14592777 | 1344 | L>I | No | 1000Genomes | |
| tmp_2_15656257_C_A | 1361 | A>E | No | 1000Genomes | |
| ENSVATH00263154 | 1370 | S>R | No | 1000Genomes | |
| tmp_2_15656318_T_A | 1381 | D>E | No | 1000Genomes | |
| ENSVATH14592778 | 1384 | M>L | No | 1000Genomes | |
| ENSVATH07911857 | 1386 | T>P | No | 1000Genomes | |
| tmp_2_15656366_G_T | 1397 | L>F | No | 1000Genomes | |
| ENSVATH05670701 | 1403 | F>L | No | 1000Genomes |
No associated diseases with Q9ZUT8
12 regional properties for Q9ZUT8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 140 - 412 | IPR003439-1 |
| domain | ABC transporter-like, ATP-binding domain | 813 - 1065 | IPR003439-2 |
| domain | AAA+ ATPase domain | 164 - 397 | IPR003593-1 |
| domain | AAA+ ATPase domain | 850 - 1042 | IPR003593-2 |
| domain | ABC-2 type transporter, transmembrane domain | 491 - 702 | IPR013525-1 |
| domain | ABC-2 type transporter, transmembrane domain | 1138 - 1352 | IPR013525-2 |
| domain | Plant PDR ABC transporter associated | 707 - 769 | IPR013581 |
| domain | ABC-transporter, N-terminal domain | 81 - 130 | IPR029481 |
| domain | ATP-binding cassette transporter, PDR-like subfamily G, domain 1 | 146 - 394 | IPR034001 |
| domain | ATP-binding cassette transporter, PDR-like subfamily G, domain 2 | 810 - 1048 | IPR034003 |
| domain | ABC transporter family G domain | 370 - 443 | IPR043926-1 |
| domain | ABC transporter family G domain | 1022 - 1096 | IPR043926-2 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ABC-type transporter activity | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
14 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q08409 | AUS1 | ATP-dependent permease AUS1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P40550 | PDR11 | ATP-dependent permease PDR11 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q8GU92 | ABCG35 | ABC transporter G family member 35 | Oryza sativa subsp japonica (Rice) | PR |
| Q8GU83 | ABCG41 | ABC transporter G family member 41 | Oryza sativa subsp japonica (Rice) | PR |
| Q9M2V6 | ABCG17 | ABC transporter G family member 17 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O81016 | ABCG32 | ABC transporter G family member 32 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC81 | ABCG43 | ABC transporter G family member 43 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC83 | ABCG41 | ABC transporter G family member 41 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LFH0 | ABCG37 | ABC transporter G family member 37 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9MAH4 | ABCG10 | ABC transporter G family member 10 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9MAG3 | ABCG24 | ABC transporter G family member 24 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SZR9 | ABCG9 | ABC transporter G family member 9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GZ52 | ABCG30 | ABC transporter G family member 30 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q7PC82 | ABCG42 | ABC transporter G family member 42 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGSSFRSSSS | RNEHEDGGDE | AEHALQWAEI | QRLPTFKRLR | SSLVDKYGEG | TEKGKKVVDV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TKLGAMERHL | MIEKLIKHIE | NDNLKLLKKI | RRRMERVGVE | FPSIEVRYEH | LGVEAACEVV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EGKALPTLWN | SLKHVFLDLL | KLSGVRTNEA | NIKILTDVSG | IISPGRLTLL | LGPPGCGKTT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LLKALSGNLE | NNLKCYGEIS | YNGHGLNEVV | PQKTSAYISQ | HDLHIAEMTT | RETIDFSARC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QGVGSRTDIM | MEVSKREKDG | GIIPDPEIDA | YMKAISVKGL | KRSLQTDYIL | KILGLDICAE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TLVGNAMKRG | ISGGQKKRLT | TAEMIVGPTK | ALFMDEITNG | LDSSTAFQII | KSLQQVAHIT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NATVFVSLLQ | PAPESYDLFD | DIVLMAEGKI | VYHGPRDDVL | KFFEECGFQC | PERKGVADFL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QEVISKKDQG | QYWLHQNLPH | SFVSVDTLSK | RFKDLEIGRK | IEEALSKPYD | ISKTHKDALS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| FNVYSLPKWE | LFRACISREF | LLMKRNYFVY | LFKTFQLVLA | AIITMTVFIR | TRMDIDIIHG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| NSYMSCLFFA | TVVLLVDGIP | ELSMTVQRLS | VFYKQKQLCF | YPAWAYAIPA | TVLKIPLSFF |
| 610 | 620 | 630 | 640 | 650 | 660 |
| ESLVWTCLTY | YVIGYTPEPY | RFFRQFMILF | AVHFTSISMF | RCIAAIFQTG | VAAMTAGSFV |
| 670 | 680 | 690 | 700 | 710 | 720 |
| MLITFVFAGF | AIPYTDMPGW | LKWGFWVNPI | SYAEIGLSVN | EFLAPRWQKM | QPTNVTLGRT |
| 730 | 740 | 750 | 760 | 770 | 780 |
| ILESRGLNYD | DYMYWVSLSA | LLGLTIIFNT | IFTLALSFLK | SPTSSRPMIS | QDKLSELQGT |
| 790 | 800 | 810 | 820 | 830 | 840 |
| KDSSVKKNKP | LDSSIKTNED | PGKMILPFKP | LTITFQDLNY | YVDVPVEMKG | QGYNEKKLQL |
| 850 | 860 | 870 | 880 | 890 | 900 |
| LSEITGAFRP | GVLTALMGIS | GAGKTTLLDV | LAGRKTSGYI | EGEIRISGFL | KVQETFARVS |
| 910 | 920 | 930 | 940 | 950 | 960 |
| GYCEQTDIHS | PSITVEESLI | YSAWLRLVPE | INPQTKIRFV | KQVLETIELE | EIKDALVGVA |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| GVSGLSTEQR | KRLTVAVELV | ANPSIIFMDE | PTTGLDARAA | AIVMRAVKNV | AETGRTIVCT |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| IHQPSIHIFE | AFDELVLLKR | GGRMIYSGPL | GQHSSCVIEY | FQNIPGVAKI | RDKYNPATWM |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| LEVTSESVET | ELDMDFAKIY | NESDLYKNNS | ELVKELSKPD | HGSSDLHFKR | TFAQNWWEQF |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| KSCLWKMSLS | YWRSPSYNLM | RIGHTFISSF | IFGLLFWNQG | KKIDTQQNLF | TVLGAIYGLV |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| LFVGINNCTS | ALQYFETERN | VMYRERFAGM | YSAFAYALAQ | VVTEIPYIFI | QSAEFVIVIY |
| 1270 | 1280 | 1290 | 1300 | 1310 | 1320 |
| PMIGFYASFS | KVFWSLYAMF | CNLLCFNYLA | MFLISITPNF | MVAAILQSLF | FTTFNIFAGF |
| 1330 | 1340 | 1350 | 1360 | 1370 | 1380 |
| LIPKPQIPKW | WVWFYYITPT | SWTLNLFFSS | QYGDIHQKIN | AFGETKTVAS | FLEDYFGFHH |
| 1390 | 1400 | 1410 | |||
| DRLMITAIIL | IAFPIALATM | YAFFVAKLNF | QKR |