Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9ZQ95

Entry ID Method Resolution Chain Position Source
AF-Q9ZQ95-F1 Predicted AlphaFoldDB

49 variants for Q9ZQ95

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH00262469 4 E>V No 1000Genomes
ENSVATH14591173 6 N>T No 1000Genomes
ENSVATH01957167 42 I>M No 1000Genomes
tmp_2_15421680_G_T 49 H>Q No 1000Genomes
ENSVATH01957166 49 H>R No 1000Genomes
tmp_2_15421582_A_G 82 L>P No 1000Genomes
ENSVATH14591170 93 T>A No 1000Genomes
ENSVATH13553412 95 M>I No 1000Genomes
ENSVATH13553411 102 F>Y No 1000Genomes
ENSVATH01957165 113 Q>E No 1000Genomes
ENSVATH14591168 137 E>K No 1000Genomes
ENSVATH05667813 145 P>T No 1000Genomes
tmp_2_15421371_C_T 152 M>I No 1000Genomes
ENSVATH05667812 155 F>L No 1000Genomes
ENSVATH07911438 160 V>I No 1000Genomes
tmp_2_15421346_T_G 161 N>H No 1000Genomes
ENSVATH13553410 167 R>H No 1000Genomes
ENSVATH14591166 171 D>E No 1000Genomes
ENSVATH05667811 172 N>K No 1000Genomes
ENSVATH14591165 177 K>Q No 1000Genomes
tmp_2_15421283_C_A 182 V>F No 1000Genomes
ENSVATH01957164 200 T>S No 1000Genomes
ENSVATH01957163 220 S>C No 1000Genomes
tmp_2_15421162_C_T 222 G>D No 1000Genomes
tmp_2_15421140_T_G 229 Q>H No 1000Genomes
ENSVATH05667809 234 A>V No 1000Genomes
tmp_2_15421116_T_G 237 K>N No 1000Genomes
ENSVATH01957160 259 V>I No 1000Genomes
tmp_2_15421034_C_T 265 E>K No 1000Genomes
ENSVATH13553407 267 G>* No 1000Genomes
ENSVATH14591163 282 D>V No 1000Genomes
ENSVATH00262466 283 S>C No 1000Genomes
ENSVATH05667808 295 G>E No 1000Genomes
ENSVATH01957158 361 I>M No 1000Genomes
tmp_2_15420742_A_G 362 L>P No 1000Genomes
tmp_2_15420730_G_T 366 S>Y No 1000Genomes
tmp_2_15420692_T_A 379 T>S No 1000Genomes
ENSVATH00262465 388 P>S No 1000Genomes
ENSVATH05667806 391 T>A No 1000Genomes
tmp_2_15420644_A_T 395 F>I No 1000Genomes
tmp_2_15420630_G_C 399 F>L No 1000Genomes
tmp_2_15420524_T_A 435 K>* No 1000Genomes
ENSVATH01957154 452 A>V No 1000Genomes
tmp_2_15420440_C_A 463 G>* No 1000Genomes
ENSVATH05667804 464 E>D No 1000Genomes
tmp_2_15420426_G_C 467 H>Q No 1000Genomes
tmp_2_15420398_G_C 477 H>D No 1000Genomes
ENSVATH14591156 481 T>S No 1000Genomes
ENSVATH05667803 495 N>K No 1000Genomes

No associated diseases with Q9ZQ95

1 regional properties for Q9ZQ95

Type Name Position InterPro Accession
conserved_site UDP-glycosyltransferase family, conserved site 355 - 398 IPR035595

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

4 GO annotations of molecular function

Name Definition
quercetin 3-O-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule.
quercetin 4'-O-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to the 4'-hydroxy group of a quercetin molecule.
quercetin 7-O-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule.
UDP-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule.

1 GO annotations of biological process

Name Definition
flavonol biosynthetic process The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.

36 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q1LZI1 UGT3A1 UDP-glucuronosyltransferase 3A1 Bos taurus (Bovine) PR
P36537 UGT2B10 UDP-glucuronosyltransferase 2B10 Homo sapiens (Human) PR
Q3SY77 UGT3A2 UDP-glucuronosyltransferase 3A2 Homo sapiens (Human) PR
O75310 UGT2B11 UDP-glucuronosyltransferase 2B11 Homo sapiens (Human) PR
P16662 UGT2B7 UDP-glucuronosyltransferase 2B7 Homo sapiens (Human) PR
Q16880 UGT8 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Homo sapiens (Human) PR
Q64676 Ugt8 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Mus musculus (Mouse) PR
Q8JZZ0 Ugt3a2 UDP-glucuronosyltransferase 3A2 Mus musculus (Mouse) PR
Q09426 Ugt8 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Rattus norvegicus (Rat) PR
Q22295 ugt-50 Putative UDP-glucuronosyltransferase ugt-50 Caenorhabditis elegans PR
Q9FE68 UGT71C5 UDP-glycosyltransferase 71C5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LML6 UGT71C4 Flavonol 3-O-glucosyltransferase UGT71C4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LML7 UGT71C3 UDP-glycosyltransferase 71C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LME8 UGT85A7 UDP-glycosyltransferase 85A7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LMF1 UGT85A3 UDP-glycosyltransferase 85A3 Arabidopsis thaliana (Mouse-ear cress) PR
O48676 UGT74B1 UDP-glycosyltransferase 74B1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQG4 UGT73B5 UDP-glycosyltransferase 73B5 Arabidopsis thaliana (Mouse-ear cress) PR
O22822 UGT74F2 UDP-glycosyltransferase 74F2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY9 UGT71B1 UDP-glycosyltransferase 71B1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY6 UGT71B6 UDP-glycosyltransferase 71B6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY5 UGT71B7 UDP-glycosyltransferase 71B7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY4 UGT71B8 UDP-glycosyltransferase 71B8 Arabidopsis thaliana (Mouse-ear cress) PR
Q94AB5 UGT76E12 Flavonol 3-O-glucosyltransferase UGT76E12 Arabidopsis thaliana (Mouse-ear cress) PR
O23382 UGT71B5 UDP-glycosyltransferase 71B5 Arabidopsis thaliana (Mouse-ear cress) PR
Q5XF20 UGT84A1 UDP-glycosyltransferase 84A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LXV0 UGT92A1 UDP-glycosyltransferase 92A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LS16 UGT76E7 UDP-glycosyltransferase 76E7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FN28 UGT79B9 UDP-glycosyltransferase 79B9 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LHJ2 UGT82A1 UDP-glycosyltransferase 82A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SCP5 UGT73C7 UDP-glycosyltransferase 73C7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SJL0 UGT86A1 UDP-glycosyltransferase 86A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ94 UGT73C5 UDP-glycosyltransferase 73C5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ96 UGT73C3 UDP-glycosyltransferase 73C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ97 UGT73C4 UDP-glycosyltransferase 73C4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ98 UGT73C2 UDP-glycosyltransferase 73C2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZVX4 UGT90A1 UDP-glycosyltransferase 90A1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAFEKNNEPF PLHFVLFPFM AQGHMIPMVD IARLLAQRGV LITIVTTPHN AARFKNVLNR
70 80 90 100 110 120
AIESGLPINL VQVKFPYQEA GLQEGQENMD LLTTMEQITS FFKAVNLLKE PVQNLIEEMS
130 140 150 160 170 180
PRPSCLISDM CLSYTSEIAK KFKIPKILFH GMGCFCLLCV NVLRKNREIL DNLKSDKEYF
190 200 210 220 230 240
IVPYFPDRVE FTRPQVPVET YVPAGWKEIL EDMVEADKTS YGVIVNSFQE LEPAYAKDFK
250 260 270 280 290 300
EARSGKAWTI GPVSLCNKVG VDKAERGNKS DIDQDECLEW LDSKEPGSVL YVCLGSICNL
310 320 330 340 350 360
PLSQLLELGL GLEESQRPFI WVIRGWEKYK ELVEWFSESG FEDRIQDRGL LIKGWSPQML
370 380 390 400 410 420
ILSHPSVGGF LTHCGWNSTL EGITAGLPML TWPLFADQFC NEKLVVQILK VGVSAEVKEV
430 440 450 460 470 480
MKWGEEEKIG VLVDKEGVKK AVEELMGESD DAKERRRRAK ELGESAHKAV EEGGSSHSNI
490
TFLLQDIMQL AQSNN