O22822
PR
Gene name |
UGT74F2 (GT, SAGT1, SGT1, At2g43820, F18O19.7) |
Protein name |
UDP-glycosyltransferase 74F2 |
Names |
AtSGT1, Salicylic acid glucosyltransferase 1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G43820 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
21 variants for O22822
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_2_18152301_T_C | 8 | V>A | No | 1000Genomes | |
| ENSVATH13630508 | 8 | V>I | No | 1000Genomes | |
| ENSVATH00273554 | 74 | D>A | No | 1000Genomes | |
| ENSVATH13630509 | 78 | D>N | No | 1000Genomes | |
| ENSVATH01985265 | 96 | Q>H | No | 1000Genomes | |
| ENSVATH05712434 | 100 | T>S | No | 1000Genomes | |
| ENSVATH01985266 | 103 | N>S | No | 1000Genomes | |
| ENSVATH05712435 | 114 | L>M | No | 1000Genomes | |
| ENSVATH05712437 | 115 | P>A | No | 1000Genomes | |
| tmp_2_18152768_C_T | 164 | L>F | No | 1000Genomes | |
| ENSVATH05712439 | 219 | V>L | No | 1000Genomes | |
| tmp_2_18153142_C_G | 259 | D>E | No | 1000Genomes | |
| ENSVATH00273556 | 295 | L>V | No | 1000Genomes | |
| ENSVATH13630513 | 314 | V>M | No | 1000Genomes | |
| ENSVATH13630514 | 315 | N>K | No | 1000Genomes | |
| ENSVATH13630535 | 317 | E>D | No | 1000Genomes | |
| ENSVATH00273557 | 380 | A>S | No | 1000Genomes | |
| tmp_2_18153545_A_C | 394 | K>Q | No | 1000Genomes | |
| tmp_2_18153562_G_T | 399 | E>D | No | 1000Genomes | |
| tmp_2_18153635_T_A | 424 | L>M | No | 1000Genomes | |
| ENSVATH05712442 | 428 | S>A | No | 1000Genomes |
No associated diseases with O22822
1 regional properties for O22822
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | UDP-glycosyltransferase family, conserved site | 336 - 379 | IPR035595 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
8 GO annotations of molecular function
| Name | Definition |
|---|---|
| benzoic acid glucosyltransferase activity | Catalysis of the reaction: benzoic acid + UDP-glucose = benzoic acid glucose ester + UDP. |
| nicotinate-O-glucosyltransferase activity | Catalysis of the reaction: nicotinate + UDP-D-glucose = O-D-glucosylnicotinate + UDP. |
| quercetin 3-O-glucosyltransferase activity | Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule. |
| quercetin 7-O-glucosyltransferase activity | Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule. |
| salicylic acid glucosyltransferase (ester-forming) activity | Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid glucose ester + UDP. |
| salicylic acid glucosyltransferase (glucoside-forming) activity | Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP. |
| UDP-glucose:4-aminobenzoate acylglucosyltransferase activity | Catalysis of the reaction: 4-aminobenzoate + UDP-glucose = p-aminobenzoate-beta-D-glucopyranosyl ester + UDP. |
| UDP-glucosyltransferase activity | Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| benzoate metabolic process | The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid. |
| para-aminobenzoic acid metabolic process | The chemical reactions and pathways involving para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins. |
| positive regulation of seed germination | Any process that activates or increase the rate of seed germination. |
| salicylic acid metabolic process | The chemical reactions and pathways involving of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid. |
36 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q1LZI1 | UGT3A1 | UDP-glucuronosyltransferase 3A1 | Bos taurus (Bovine) | PR |
| P36537 | UGT2B10 | UDP-glucuronosyltransferase 2B10 | Homo sapiens (Human) | PR |
| Q3SY77 | UGT3A2 | UDP-glucuronosyltransferase 3A2 | Homo sapiens (Human) | PR |
| O75310 | UGT2B11 | UDP-glucuronosyltransferase 2B11 | Homo sapiens (Human) | PR |
| P16662 | UGT2B7 | UDP-glucuronosyltransferase 2B7 | Homo sapiens (Human) | PR |
| Q16880 | UGT8 | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase | Homo sapiens (Human) | PR |
| Q64676 | Ugt8 | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase | Mus musculus (Mouse) | PR |
| Q8JZZ0 | Ugt3a2 | UDP-glucuronosyltransferase 3A2 | Mus musculus (Mouse) | PR |
| Q09426 | Ugt8 | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase | Rattus norvegicus (Rat) | PR |
| Q22295 | ugt-50 | Putative UDP-glucuronosyltransferase ugt-50 | Caenorhabditis elegans | PR |
| Q9FE68 | UGT71C5 | UDP-glycosyltransferase 71C5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LML6 | UGT71C4 | Flavonol 3-O-glucosyltransferase UGT71C4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LML7 | UGT71C3 | UDP-glycosyltransferase 71C3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQG4 | UGT73B5 | UDP-glycosyltransferase 73B5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZVX4 | UGT90A1 | UDP-glycosyltransferase 90A1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQ98 | UGT73C2 | UDP-glycosyltransferase 73C2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQ97 | UGT73C4 | UDP-glycosyltransferase 73C4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQ96 | UGT73C3 | UDP-glycosyltransferase 73C3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQ95 | UGT73C6 | UDP-glycosyltransferase 73C6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQ94 | UGT73C5 | UDP-glycosyltransferase 73C5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SJL0 | UGT86A1 | UDP-glycosyltransferase 86A1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LSY9 | UGT71B1 | UDP-glycosyltransferase 71B1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LSY6 | UGT71B6 | UDP-glycosyltransferase 71B6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LSY5 | UGT71B7 | UDP-glycosyltransferase 71B7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LSY4 | UGT71B8 | UDP-glycosyltransferase 71B8 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LHJ2 | UGT82A1 | UDP-glycosyltransferase 82A1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SCP5 | UGT73C7 | UDP-glycosyltransferase 73C7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O23382 | UGT71B5 | UDP-glycosyltransferase 71B5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LXV0 | UGT92A1 | UDP-glycosyltransferase 92A1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FN28 | UGT79B9 | UDP-glycosyltransferase 79B9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q5XF20 | UGT84A1 | UDP-glycosyltransferase 84A1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94AB5 | UGT76E12 | Flavonol 3-O-glucosyltransferase UGT76E12 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LME8 | UGT85A7 | UDP-glycosyltransferase 85A7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LMF1 | UGT85A3 | UDP-glycosyltransferase 85A3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LS16 | UGT76E7 | UDP-glycosyltransferase 76E7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O48676 | UGT74B1 | UDP-glycosyltransferase 74B1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEHKRGHVLA | VPYPTQGHIT | PFRQFCKRLH | FKGLKTTLAL | TTFVFNSINP | DLSGPISIAT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ISDGYDHGGF | ETADSIDDYL | KDFKTSGSKT | IADIIQKHQT | SDNPITCIVY | DAFLPWALDV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AREFGLVATP | FFTQPCAVNY | VYYLSYINNG | SLQLPIEELP | FLELQDLPSF | FSVSGSYPAY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FEMVLQQFIN | FEKADFVLVN | SFQELELHEN | ELWSKACPVL | TIGPTIPSIY | LDQRIKSDTG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YDLNLFESKD | DSFCINWLDT | RPQGSVVYVA | FGSMAQLTNV | QMEELASAVS | NFSFLWVVRS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SEEEKLPSGF | LETVNKEKSL | VLKWSPQLQV | LSNKAIGCFL | THCGWNSTME | ALTFGVPMVA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| MPQWTDQPMN | AKYIQDVWKA | GVRVKTEKES | GIAKREEIEF | SIKEVMEGER | SKEMKKNVKK |
| 430 | 440 | ||||
| WRDLAVKSLN | EGGSTDTNID | TFVSRVQSK |