Q16880
PR
Gene name |
UGT8 |
Protein name |
2-hydroxyacylsphingosine 1-beta-galactosyltransferase |
Names |
Ceramide UDP-galactosyltransferase, Cerebroside synthase, UDP-galactose-ceramide galactosyltransferase |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:7368 |
EC number |
2.4.1.47: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q16880
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q16880-F1 | Predicted | AlphaFoldDB |
327 variants for Q16880
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs756087753 CA3053420 |
5 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1196426669 CA358000936 |
6 | P>L | No |
ClinGen gnomAD |
|
|
CA358000941 rs1578415194 |
7 | Y>C | No |
ClinGen Ensembl |
|
|
CA358000986 rs1322911390 |
13 | S>R | No |
ClinGen gnomAD |
|
|
rs551137363 CA358000989 |
14 | A>S | No |
ClinGen ExAC gnomAD |
|
|
rs551137363 CA3053422 |
14 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs757394177 CA3053423 |
17 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs977238511 CA104626785 |
18 | A>E | No |
ClinGen TOPMed gnomAD |
|
|
CA104626784 rs1043347555 |
18 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs977238511 CA358001014 |
18 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA3053426 rs772120149 |
20 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358001031 rs1230493110 |
21 | A>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA358001028 rs1330029348 |
21 | A>T | No |
ClinGen gnomAD |
|
|
rs747287967 CA3053429 |
25 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA3053431 rs145205528 |
26 | V>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3053432 rs145205528 |
26 | V>M | Variant assessed as Somatic; 0.0001386 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1174282310 CA358001072 |
28 | P>S | No |
ClinGen TOPMed |
|
|
rs774055289 CA3053434 |
30 | M>L | No |
ClinGen ExAC gnomAD |
|
|
rs1173051047 CA358001089 |
30 | M>T | No |
ClinGen gnomAD |
|
|
CA358001130 rs1251936769 |
35 | M>I | No |
ClinGen gnomAD |
|
|
rs759228056 CA3053435 |
35 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3053436 rs201002468 |
36 | Y>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1578415355 CA358001153 |
38 | F>L | No |
ClinGen Ensembl |
|
|
rs369703582 CA3053437 |
39 | K>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1406867604 CA358001163 |
40 | T>A | No |
ClinGen gnomAD |
|
|
rs369373697 CA3053438 |
40 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA358001166 rs369373697 |
40 | T>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1406867604 CA358001164 |
40 | T>S | No |
ClinGen gnomAD |
|
|
CA3053441 rs753818310 |
41 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358001171 rs1206560843 |
42 | A>T | No |
ClinGen TOPMed |
|
|
rs149131940 CA3053443 |
43 | S>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA358001184 rs1560676041 |
44 | A>T | No |
ClinGen Ensembl |
|
|
rs150551951 CA3053447 |
46 | H>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA358001201 rs768880144 |
46 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1280490256 CA358001206 |
47 | E>D | No |
ClinGen gnomAD |
|
|
CA3053449 rs200875294 |
47 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs200875294 CA104626790 |
47 | E>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs370760289 CA3053450 |
51 | H>R | No |
ClinGen ESP ExAC gnomAD |
|
|
rs770216585 CA3053451 |
52 | T>S | No |
ClinGen ExAC gnomAD |
|
|
CA104626791 rs769180706 |
53 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
rs897545387 CA104626792 |
54 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs774987624 CA3053455 |
61 | D>H | No |
ClinGen ExAC gnomAD |
|
|
rs760580655 CA3053456 |
62 | I>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs760580655 CA3053457 |
62 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3053459 rs114818124 |
63 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs765219145 CA3053460 |
63 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs750548143 CA3053461 |
66 | N>D | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 67 | H>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3053462 rs758379102 |
67 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1437485580 CA358001354 |
70 | L>P | No |
ClinGen gnomAD |
|
|
rs1368478542 CA358001362 |
71 | Q>H | No |
ClinGen gnomAD |
|
|
CA358001360 rs1276354982 |
71 | Q>R | No |
ClinGen gnomAD |
|
|
rs780372131 CA3053463 |
72 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3053464 rs141798376 |
72 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA358001389 rs1373455475 |
76 | I>V | No |
ClinGen TOPMed |
|
|
rs1027681211 CA104626794 |
80 | T>I | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 80 | T>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3053465 rs546892524 |
84 | A>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1223268640 CA358001448 |
84 | A>V | No |
ClinGen gnomAD |
|
|
CA358001466 rs781541134 |
87 | Q>L | No |
ClinGen ExAC gnomAD |
|
|
rs781541134 CA3053466 |
87 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
CA358001486 rs1355169778 |
90 | M>T | No |
ClinGen TOPMed gnomAD |
|
|
rs374700060 CA3053468 |
91 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs370438338 CA3053467 |
91 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA104626797 rs1031431760 |
92 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1560676380 CA358001506 |
93 | I>T | No |
ClinGen Ensembl |
|
|
CA358001523 rs1560676395 |
96 | G>R | No |
ClinGen Ensembl |
|
|
CA3053470 rs745419490 |
97 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775284168 CA3053472 |
100 | A>P | No |
ClinGen ExAC gnomAD |
|
|
rs1298078821 CA358001560 COSM201859 |
102 | E>K | Variant assessed as Somatic; 0.0 impact. large_intestine endometrium breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA358001589 rs1578415767 |
106 | I>L | No |
ClinGen Ensembl |
|
|
CA104626798 rs1022455967 |
106 | I>M | No |
ClinGen TOPMed |
|
|
rs137983750 CA3053474 |
107 | L>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA104626799 rs939203331 |
109 | H>R | No |
ClinGen Ensembl |
|
|
CA358001608 rs1413852774 |
109 | H>Y | No |
ClinGen TOPMed |
|
|
CA358001627 rs1225187296 |
111 | T>I | No |
ClinGen gnomAD |
|
|
CA3053475 rs776592565 |
115 | D>A | No |
ClinGen ExAC gnomAD |
|
|
rs776592565 CA3053476 |
115 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs765306681 CA3053477 COSM1618308 |
117 | M>I | liver [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA358001663 rs1356405979 |
117 | M>L | No |
ClinGen gnomAD |
|
|
rs1159400206 CA358001673 |
118 | V>F | No |
ClinGen gnomAD |
|
|
rs562002492 CA3053478 |
120 | N>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA358001692 rs1213400141 |
121 | H>Y | No |
ClinGen gnomAD |
|
|
CA3053480 rs766364291 |
125 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
rs751589059 CA3053481 |
126 | G>C | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 126 | G>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 129 | K>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358001756 rs1165229419 |
130 | E>D | No |
ClinGen TOPMed |
|
|
rs1165079106 CA358001749 |
130 | E>K | No |
ClinGen gnomAD |
|
|
CA358001763 rs1475953902 |
131 | K>N | No |
ClinGen TOPMed |
|
|
CA104626801 rs928205856 |
132 | F>L | No |
ClinGen TOPMed |
|
|
rs1458911664 CA358001781 |
134 | L>V | No |
ClinGen Ensembl |
|
| TCGA novel | 138 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1317545842 CA358001819 |
140 | N>S | No |
ClinGen gnomAD |
|
| TCGA novel | 142 | M>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM3775493 CA104626803 rs868025816 |
144 | G>R | Variant assessed as Somatic; impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated Ensembl NCI-TCGA |
|
CA3053487 rs141691690 |
146 | V>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3053488 rs150529068 |
149 | H>Y | No |
ClinGen ESP ExAC gnomAD |
|
|
RCV000956247 rs111563693 CA3053489 |
152 | G>R | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA3053490 rs760002151 |
153 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs768456240 CA3053491 |
154 | K>E | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 161 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs765529828 CA3053494 |
164 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs773266808 CA3053495 |
166 | A>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 167 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1283740995 CA358001998 |
167 | E>A | No |
ClinGen TOPMed |
|
|
CA3053496 rs762802414 |
169 | G>C | No |
ClinGen ExAC gnomAD |
|
|
rs371402834 CA3053498 COSM585664 |
171 | P>S | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA358002033 rs1336327132 |
173 | P>S | No |
ClinGen TOPMed |
|
|
rs1451358045 CA358002049 |
175 | A>V | No |
ClinGen gnomAD |
|
|
CA3053503 rs764375660 |
177 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs1560676854 CA358002064 |
178 | P>A | No |
ClinGen Ensembl |
|
|
CA358002112 rs1354234975 |
185 | T>A | No |
ClinGen gnomAD |
|
|
rs1019501372 CA104626804 |
185 | T>K | No |
ClinGen TOPMed |
|
|
COSM146074 CA3053505 rs568970139 |
187 | R>C | Variant assessed as Somatic; 0.0 impact. haematopoietic_and_lymphoid_tissue [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA358002125 rs568970139 |
187 | R>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA104626805 rs866951708 COSM1050280 |
187 | R>H | large_intestine Variant assessed as Somatic; impact. endometrium [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
rs138986527 CA104626806 COSM107510 |
188 | M>I | skin [Cosmic] | No |
ClinGen cosmic curated Ensembl |
|
CA3053508 rs754514949 |
195 | K>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs267599991 CA104626807 |
198 | G>D | No |
ClinGen Ensembl |
|
|
CA3053511 rs769419385 |
201 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1485377064 CA358002239 |
204 | R>* | No |
ClinGen gnomAD |
|
|
CA358002268 rs1252849477 |
208 | S>T | No |
ClinGen gnomAD |
|
|
CA3053514 rs770801564 |
211 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA3053515 rs774311331 |
212 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs759658397 CA3053516 |
216 | E>* | No |
ClinGen ExAC gnomAD |
|
|
CA3053517 COSM1186637 rs767582586 |
217 | R>S | lung [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs775484028 CA3053518 |
218 | I>M | No |
ClinGen ExAC gnomAD |
|
|
rs533936789 CA3053519 |
220 | Q>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs764332315 CA3053520 |
221 | K>M | No |
ClinGen ExAC gnomAD |
|
|
rs754186990 CA3053521 |
221 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3053522 rs757610362 |
222 | Y>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765714306 CA3053523 |
223 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358002374 rs1301872081 |
224 | L>P | No |
ClinGen gnomAD |
|
|
CA104626809 rs750954771 |
224 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3053526 VAR_052466 rs4148254 |
226 | P>L | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs755743614 CA3053528 |
228 | K>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs777438600 CA3053529 |
231 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA358002425 rs1199240083 |
232 | D>Y | No |
ClinGen Ensembl |
|
|
rs1326412021 CA358002440 |
234 | V>L | No |
ClinGen TOPMed |
|
|
CA358002478 rs1450026783 |
240 | W>R | No |
ClinGen gnomAD |
|
|
rs181812605 CA104626815 |
241 | M>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3053532 rs181812605 |
241 | M>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs745812383 CA3053533 |
244 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs61733375 CA3053534 |
245 | D>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA3053537 rs768800801 |
246 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs768800801 CA3053538 |
246 | V>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3053536 rs760771718 COSM273439 |
246 | V>I | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA358002521 rs1396195889 |
247 | A>T | No |
ClinGen TOPMed |
|
|
rs1370848456 CA358002541 |
250 | F>L | No |
ClinGen gnomAD |
|
|
CA358002559 rs1578416482 |
252 | R>S | No |
ClinGen Ensembl |
|
|
CA104626816 rs750749006 |
254 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358002569 rs1298425682 |
254 | T>I | No |
ClinGen gnomAD |
|
|
CA3053541 rs750749006 |
254 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1305817814 CA358002583 |
257 | N>D | No |
ClinGen gnomAD |
|
|
rs763565520 CA3053542 |
258 | V>D | No |
ClinGen ExAC gnomAD |
|
|
rs1039442570 CA104626817 |
259 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
rs752286423 CA3053544 |
265 | L>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3053547 rs753512165 |
267 | K>N | No |
ClinGen ExAC gnomAD |
|
|
rs1188174109 CA358002657 |
269 | A>S | No |
ClinGen gnomAD |
|
|
CA3053549 rs199775914 |
271 | P>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3053548 rs199775914 RCV000436700 |
271 | P>S | No |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
|
CA358002683 rs1352977065 |
273 | P>L | No |
ClinGen TOPMed |
|
|
CA3053550 rs745617977 |
273 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1308859555 CA357741806 |
275 | D>H | No |
ClinGen TOPMed |
|
|
CA357741819 rs1368638945 |
276 | L>I | No |
ClinGen gnomAD |
|
|
rs754963742 CA3053596 |
279 | W>C | No |
ClinGen ExAC gnomAD |
|
|
rs780951943 CA3053597 |
281 | N>H | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 282 | G>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1271769193 CA357741926 |
284 | N>K | No |
ClinGen gnomAD |
|
|
rs868236165 CA103637045 |
285 | E>K | No |
ClinGen Ensembl |
|
|
CA357741955 rs1468652873 |
287 | G>S | No |
ClinGen gnomAD |
|
|
rs1255323771 CA357741971 |
289 | V>L | No |
ClinGen gnomAD |
|
|
CA103637055 rs201130569 |
294 | G>E | No |
ClinGen Ensembl |
|
|
CA357742025 rs1467448681 |
297 | V>A | No |
ClinGen gnomAD |
|
|
CA3053599 rs748298837 |
299 | Y>C | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 300 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3053600 rs756236247 |
301 | S>L | No |
ClinGen ExAC gnomAD |
|
|
rs771207594 CA3053603 |
303 | D>E | No |
ClinGen ExAC gnomAD |
|
|
rs151058343 CA3053602 |
303 | D>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs930175519 CA103637110 |
304 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
CA357742083 rs1167419608 |
306 | N>I | No |
ClinGen gnomAD |
|
|
CA357742106 rs1439966593 |
310 | G>R | No |
ClinGen gnomAD |
|
|
CA3053606 rs772679865 |
313 | G>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1269099621 CA357742145 |
316 | P>S | No |
ClinGen gnomAD |
|
|
rs764723184 CA3053609 |
320 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs772729554 CA3053629 |
326 | P>H | No |
ClinGen ExAC gnomAD |
|
|
rs772729554 CA357742231 |
326 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA357742227 rs1255599242 |
326 | P>T | No |
ClinGen gnomAD |
|
|
CA3053630 rs762408070 |
329 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs559172034 CA3053632 |
338 | I>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1242454396 CA357742314 |
339 | E>K | No |
ClinGen Ensembl |
|
| TCGA novel | 340 | W>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA357742322 rs1325497481 |
340 | W>R | No |
ClinGen TOPMed |
|
|
rs1388539358 CA357742332 |
341 | L>I | No |
ClinGen TOPMed |
|
|
COSM1753499 CA103638376 rs1048000224 |
345 | D>N | urinary_tract [Cosmic] | No |
ClinGen cosmic curated Ensembl |
|
CA3053651 rs770333571 |
349 | H>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs369935663 CA3053652 |
351 | K>E | No |
ClinGen ESP ExAC gnomAD |
|
|
CA357742413 rs1341813817 |
351 | K>R | No |
ClinGen TOPMed |
|
|
rs1295817133 CA357742423 |
352 | I>M | No |
ClinGen TOPMed |
|
|
rs939032234 CA103640450 |
353 | K>R | No |
ClinGen TOPMed |
|
|
CA103640465 rs201757511 |
356 | L>M | No |
ClinGen Ensembl |
|
|
rs769980791 CA103640469 |
363 | S>G | No |
ClinGen gnomAD |
|
|
CA357742518 rs1237101519 |
366 | E>G | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA357742526 rs1578469841 |
367 | T>S | No |
ClinGen Ensembl |
|
|
VAR_052467 CA3053654 rs11098261 |
368 | I>M | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs759111551 COSM354783 CA3053653 |
368 | I>V | lung [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA3053655 rs775444770 |
369 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
CA357742541 rs1253224054 |
370 | H>Y | No |
ClinGen gnomAD |
|
|
CA357742881 rs1191649636 |
385 | D>G | No |
ClinGen gnomAD |
|
|
rs764180439 CA3053657 |
386 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3053659 rs762019680 |
390 | V>I | No |
ClinGen ExAC gnomAD |
|
|
CA3053660 rs563311383 |
391 | Q>R | No |
ClinGen 1000Genomes ExAC |
|
|
CA3053661 rs750461264 |
394 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA103640521 rs867183770 |
396 | G>R | No |
ClinGen Ensembl |
|
|
rs1165243891 CA357742963 |
397 | I>M | No |
ClinGen gnomAD |
|
|
CA103640538 rs867768477 |
401 | W>* | No |
ClinGen Ensembl |
|
|
rs1367522912 CA357743006 |
404 | V>I | No |
ClinGen gnomAD |
|
|
rs751958761 CA3053667 |
408 | E>G | No |
ClinGen ExAC |
|
|
rs751958761 CA3053666 |
408 | E>V | No |
ClinGen ExAC |
|
|
rs1297850638 CA357743042 |
409 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
CA357743051 rs1205358432 |
410 | Y>C | No |
ClinGen TOPMed |
|
|
rs1305950399 CA357743047 |
410 | Y>H | No |
ClinGen gnomAD |
|
| TCGA novel | 414 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs148890217 CA3053670 |
415 | K>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs892534582 CA103640628 |
415 | K>T | No |
ClinGen Ensembl |
|
|
rs1360619233 CA357743089 |
416 | V>A | No |
ClinGen TOPMed |
|
|
rs201342678 CA3053671 |
418 | N>S | No |
ClinGen 1000Genomes ExAC TOPMed |
|
|
rs1211589783 CA357743116 |
420 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
CA3053672 rs745331371 |
420 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA3053674 rs775263216 |
421 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1373770804 CA357743203 |
423 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
rs1225318306 CA357743206 |
423 | R>H | No |
ClinGen gnomAD |
|
|
CA357743219 rs1439937747 |
424 | Q>H | No |
ClinGen TOPMed |
|
|
rs1304700683 CA357743223 |
425 | R>G | No |
ClinGen gnomAD |
|
|
rs762999772 CA3053703 |
428 | K>M | No |
ClinGen ExAC gnomAD |
|
|
rs773177758 CA3053702 |
428 | K>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1368739961 CA357743270 |
429 | L>F | No |
ClinGen TOPMed |
|
|
CA357743284 rs1307522935 |
430 | S>L | No |
ClinGen TOPMed |
|
|
CA357743293 rs1425435512 |
431 | E>G | No |
ClinGen TOPMed |
|
|
rs1484428990 CA357743306 |
432 | I>T | No |
ClinGen gnomAD |
|
|
rs1387276292 CA357743325 |
434 | K>E | No |
ClinGen TOPMed |
|
|
CA357743366 rs1481163907 |
437 | P>R | No |
ClinGen gnomAD |
|
|
rs759764366 CA3053706 |
437 | P>S | No |
ClinGen ExAC gnomAD |
|
|
COSM293349 CA3053707 rs767674399 |
439 | H>Y | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA357743405 rs1378949276 |
440 | P>L | No |
ClinGen gnomAD |
|
|
CA357743434 COSM1231702 rs1174858436 |
443 | R>Q | Variant assessed as Somatic; 0.0 impact. large_intestine breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs371750245 CA3053711 |
445 | I>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3053710 rs551586225 |
445 | I>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA3053709 rs761081352 |
445 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs566522909 RCV000908615 CA3053712 |
446 | Y>C | No |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
|
CA357743479 rs1444036512 |
448 | I>L | No |
ClinGen gnomAD |
|
|
CA357743487 rs1329075502 |
449 | D>H | No |
ClinGen gnomAD |
|
|
rs779724694 CA3053713 |
449 | D>V | No |
ClinGen ExAC gnomAD |
|
|
rs754712627 CA3053715 |
450 | Y>* | No |
ClinGen ExAC gnomAD |
|
|
CA3053716 rs780868900 |
453 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA3053717 rs747939994 |
453 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3053718 rs149080130 RCV000904877 |
455 | N>S | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs749224062 CA3053720 |
457 | A>D | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 457 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs774435490 CA3053722 |
461 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA103647360 rs946873966 |
462 | A>T | No |
ClinGen Ensembl |
|
| TCGA novel | 462 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA103647384 rs772318028 |
463 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3053724 rs772318028 |
463 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 464 | V>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs761012593 CA3053726 |
467 | I>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3053727 rs555231076 |
468 | S>P | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1308916553 CA357743749 |
471 | Q>H | No |
ClinGen TOPMed |
|
|
CA3053730 rs765802959 |
471 | Q>R | No |
ClinGen ExAC |
|
|
CA357743758 rs1189722997 |
472 | Y>H | No |
ClinGen Ensembl |
|
| TCGA novel | 474 | L>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA357743791 rs535480025 |
475 | L>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA357743806 rs1221952946 |
477 | I>T | No |
ClinGen TOPMed |
|
|
CA3053732 rs556905006 |
477 | I>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA3053734 rs752387548 |
478 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA103647447 COSM420234 rs77695673 |
478 | A>S | Variant assessed as Somatic; impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated Ensembl NCI-TCGA |
|
rs77695673 CA103647440 |
478 | A>T | No |
ClinGen Ensembl |
|
|
CA357743821 rs1283893891 |
480 | V>M | No |
ClinGen TOPMed |
|
|
rs1369065100 CA357743850 |
484 | G>V | No |
ClinGen Ensembl |
|
|
rs1578479639 CA357743859 |
486 | A>P | No |
ClinGen Ensembl |
|
|
rs755651521 CA3053735 |
487 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs1363501471 CA357743870 |
488 | L>I | No |
ClinGen gnomAD |
|
|
rs749033096 CA3053737 |
489 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749033096 CA357743881 |
489 | Y>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3053740 rs746007469 |
493 | S>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs577333010 CA3053741 |
494 | W>G | No |
ClinGen ExAC gnomAD |
|
|
rs929468365 CA103647500 |
494 | W>S | No |
ClinGen TOPMed |
|
|
CA357743920 rs1346120592 |
495 | V>A | No |
ClinGen TOPMed |
|
|
CA3053742 rs545962121 |
495 | V>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 496 | T>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3053744 rs768716521 |
498 | F>S | No |
ClinGen ExAC gnomAD |
|
|
CA103647537 rs1051114979 |
500 | Y>C | No |
ClinGen gnomAD |
|
|
CA103647534 rs377204507 |
500 | Y>D | No |
ClinGen ESP TOPMed |
|
|
rs762239558 CA3053746 |
501 | R>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 503 | I>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3053747 rs369737744 |
503 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs148217774 CA3053749 |
504 | K>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3053750 rs767054172 |
504 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755812681 CA3053752 |
507 | W>L | No |
ClinGen ExAC gnomAD |
|
|
rs141178340 CA3053751 |
507 | W>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1355711044 CA357744004 |
508 | S>T | No |
ClinGen gnomAD |
|
|
CA357744020 rs1234232861 |
510 | N>S | No |
ClinGen gnomAD |
|
|
CA103647573 rs372348441 |
511 | K>E | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA3053754 rs147354647 |
512 | H>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs183262188 CA3053753 |
512 | H>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1354736740 CA357744030 |
512 | H>Y | No |
ClinGen gnomAD |
|
|
CA103647595 rs572629718 |
513 | S>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA3053757 rs369142444 |
515 | V>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs137869490 CA103647618 |
518 | H>R | No |
ClinGen ESP TOPMed |
|
|
CA357744092 rs1578479960 |
521 | N>D | No |
ClinGen Ensembl |
|
|
CA3053759 rs143336365 |
521 | N>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3053760 rs199828337 |
523 | I>M | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
COSM2155299 CA357744112 rs1290898525 |
524 | L>F | Variant assessed as Somatic; impact. central_nervous_system [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
CA357744141 rs1578480019 |
528 | Y>C | No |
ClinGen Ensembl |
|
|
rs774647733 CA3053763 |
528 | Y>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 530 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA357744155 rs1387053276 |
530 | R>K | No |
ClinGen TOPMed gnomAD |
|
|
rs1375379387 CA357744161 |
531 | N>D | No |
ClinGen TOPMed |
|
|
CA3053765 rs773641223 |
532 | G>V | No |
ClinGen ExAC gnomAD |
|
|
rs1025445689 CA357744176 |
533 | H>P | No |
ClinGen gnomAD |
|
|
rs1025445689 CA103647680 |
533 | H>R | No |
ClinGen gnomAD |
|
|
CA103647696 rs111805017 |
534 | I>S | No |
ClinGen gnomAD |
|
|
rs111805017 CA103647693 |
534 | I>T | No |
ClinGen gnomAD |
|
|
rs1578480076 CA357744181 |
534 | I>V | No |
ClinGen Ensembl |
|
|
CA103647703 rs1010056652 |
535 | K>E | No |
ClinGen TOPMed gnomAD |
|
|
rs1280585916 CA357744228 |
540 | V>A | No |
ClinGen gnomAD |
No associated diseases with Q16880
1 regional properties for Q16880
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Phosphorylase pyridoxal-phosphate attachment site | 679 - 691 | IPR035090 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.47 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity | Catalysis of the reaction: UDP-galactose + 2-(2-hydroxyacyl)sphingosine = UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine. |
| N-acylsphingosine galactosyltransferase activity | Catalysis of the reaction: ceramide + UDP-galactose = D-galactosylceramide + UDP. |
| UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity | Catalysis of the reaction: UDP-D-galactose + a glucosylceramide = a lactosylceramide + uridine-5'-diphosphate. The glucosylceramide has sphinganine as the long chain base. |
8 GO annotations of biological process
| Name | Definition |
|---|---|
| central nervous system development | The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. |
| cytoskeleton organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. |
| galactosylceramide biosynthetic process | The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. |
| glycosphingolipid metabolic process | The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide. |
| neuron projection morphogenesis | The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites. |
| paranodal junction assembly | Formation of the junction between an axon and the glial cell that forms the myelin sheath. Paranodal junctions form at each paranode, i.e. at the ends of the unmyelinated nodes of Ranvier. |
| peripheral nervous system development | The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. |
| protein localization to paranode region of axon | A cellular protein localization process in which a protein is transported to, or maintained at, the paranode region of an axon. |
36 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q1LZI1 | UGT3A1 | UDP-glucuronosyltransferase 3A1 | Bos taurus (Bovine) | PR |
| O75310 | UGT2B11 | UDP-glucuronosyltransferase 2B11 | Homo sapiens (Human) | PR |
| P16662 | UGT2B7 | UDP-glucuronosyltransferase 2B7 | Homo sapiens (Human) | PR |
| Q3SY77 | UGT3A2 | UDP-glucuronosyltransferase 3A2 | Homo sapiens (Human) | PR |
| P36537 | UGT2B10 | UDP-glucuronosyltransferase 2B10 | Homo sapiens (Human) | PR |
| Q8JZZ0 | Ugt3a2 | UDP-glucuronosyltransferase 3A2 | Mus musculus (Mouse) | PR |
| Q64676 | Ugt8 | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase | Mus musculus (Mouse) | PR |
| Q09426 | Ugt8 | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase | Rattus norvegicus (Rat) | PR |
| Q22295 | ugt-50 | Putative UDP-glucuronosyltransferase ugt-50 | Caenorhabditis elegans | PR |
| Q9LSY6 | UGT71B6 | UDP-glycosyltransferase 71B6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O22822 | UGT74F2 | UDP-glycosyltransferase 74F2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O23382 | UGT71B5 | UDP-glycosyltransferase 71B5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q5XF20 | UGT84A1 | UDP-glycosyltransferase 84A1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94AB5 | UGT76E12 | Flavonol 3-O-glucosyltransferase UGT76E12 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FE68 | UGT71C5 | UDP-glycosyltransferase 71C5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FN28 | UGT79B9 | UDP-glycosyltransferase 79B9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LHJ2 | UGT82A1 | UDP-glycosyltransferase 82A1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LME8 | UGT85A7 | UDP-glycosyltransferase 85A7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LMF1 | UGT85A3 | UDP-glycosyltransferase 85A3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LML6 | UGT71C4 | Flavonol 3-O-glucosyltransferase UGT71C4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LML7 | UGT71C3 | UDP-glycosyltransferase 71C3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LS16 | UGT76E7 | UDP-glycosyltransferase 76E7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LSY4 | UGT71B8 | UDP-glycosyltransferase 71B8 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LSY5 | UGT71B7 | UDP-glycosyltransferase 71B7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LSY9 | UGT71B1 | UDP-glycosyltransferase 71B1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LXV0 | UGT92A1 | UDP-glycosyltransferase 92A1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SCP5 | UGT73C7 | UDP-glycosyltransferase 73C7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SJL0 | UGT86A1 | UDP-glycosyltransferase 86A1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQ94 | UGT73C5 | UDP-glycosyltransferase 73C5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQ95 | UGT73C6 | UDP-glycosyltransferase 73C6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQ96 | UGT73C3 | UDP-glycosyltransferase 73C3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQ97 | UGT73C4 | UDP-glycosyltransferase 73C4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQ98 | UGT73C2 | UDP-glycosyltransferase 73C2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O48676 | UGT74B1 | UDP-glycosyltransferase 74B1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQG4 | UGT73B5 | UDP-glycosyltransferase 73B5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZVX4 | UGT90A1 | UDP-glycosyltransferase 90A1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKSYTPYFIL | LWSAVGIAKA | AKIIIVPPIM | FESHMYIFKT | LASALHERGH | HTVFLLSEGR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DIAPSNHYSL | QRYPGIFNST | TSDAFLQSKM | RNIFSGRLTA | IELFDILDHY | TKNCDLMVGN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HALIQGLKKE | KFDLLLVDPN | DMCGFVIAHL | LGVKYAVFST | GLWYPAEVGA | PAPLAYVPEF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NSLLTDRMNL | LQRMKNTGVY | LISRLGVSFL | VLPKYERIMQ | KYNLLPEKSM | YDLVHGSSLW |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MLCTDVALEF | PRPTLPNVVY | VGGILTKPAS | PLPEDLQRWV | NGANEHGFVL | VSFGAGVKYL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SEDIANKLAG | ALGRLPQKVI | WRFSGPKPKN | LGNNTKLIEW | LPQNDLLGHS | KIKAFLSHGG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LNSIFETIYH | GVPVVGIPLF | GDHYDTMTRV | QAKGMGILLE | WKTVTEKELY | EALVKVINNP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SYRQRAQKLS | EIHKDQPGHP | VNRTIYWIDY | IIRHNGAHHL | RAAVHQISFC | QYFLLDIAFV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LLLGAALLYF | LLSWVTKFIY | RKIKSLWSRN | KHSTVNGHYH | NGILNGKYKR | NGHIKHEKKV |
| K |