Q5XF20

PR
Gene name
UGT84A1
Protein name
UDP-glycosyltransferase 84A1
Names
Hydroxycinnamate glucosyltransferase 2, AtHCAGT2
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT4G15480
EC number
2.4.1.120: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

411-490 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5XF20

Entry ID Method Resolution Chain Position Source
AF-Q5XF20-F1 Predicted AlphaFoldDB

67 variants for Q5XF20

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH02843955 18 I>F No 1000Genomes
ENSVATH02843952 40 L>F No 1000Genomes
tmp_4_8850313_C_T 54 E>K No 1000Genomes
tmp_4_8850285_G_A 63 A>V No 1000Genomes
tmp_4_8850261_A_C 71 L>R No 1000Genomes
tmp_4_8850255_G_A 73 P>L No 1000Genomes
tmp_4_8850227_C_A 82 E>D No 1000Genomes
ENSVATH06677580 83 F>C No 1000Genomes
tmp_4_8850186_G_T 96 A>D No 1000Genomes
ENSVATH02843951 103 A>S No 1000Genomes
ENSVATH11793827 107 S>N No 1000Genomes
tmp_4_8850057_A_C 139 V>G No 1000Genomes
tmp_4_8850028_G_A 149 P>S No 1000Genomes
tmp_4_8849977_G_A 166 H>Y No 1000Genomes
tmp_4_8849932_C_T 181 E>K No 1000Genomes
ENSVATH00508146 194 N>H No 1000Genomes
ENSVATH00508145 208 T>A No 1000Genomes
tmp_4_8849817_T_C 219 K>R No 1000Genomes
tmp_4_8849804_C_A 223 K>N No 1000Genomes
ENSVATH06677575 229 I>L No 1000Genomes
tmp_4_8849773_A_T 234 S>T No 1000Genomes
ENSVATH06677574 237 Q>P No 1000Genomes
ENSVATH14205685 243 M>T No 1000Genomes
ENSVATH02843948 245 S>N No 1000Genomes
tmp_4_8849738_A_T 245 S>R No 1000Genomes
ENSVATH02843946 260 R>K No 1000Genomes
tmp_4_8849680_C_T 265 D>N No 1000Genomes
ENSVATH09577887 278 L>P No 1000Genomes
ENSVATH00508139 282 D>E No 1000Genomes
ENSVATH06677573 302 Q>P No 1000Genomes
tmp_4_8849553_T_C 307 E>G No 1000Genomes
ENSVATH02843942 310 H>Y No 1000Genomes
ENSVATH11793663 315 S>A No 1000Genomes
tmp_4_8849479_C_T 332 V>I No 1000Genomes
ENSVATH00508133 341 L>F No 1000Genomes
tmp_4_8849444_C_G 343 E>D No 1000Genomes
tmp_4_8849442_C_T 344 S>N No 1000Genomes
ENSVATH00508132 346 A>S No 1000Genomes
ENSVATH06677572 348 G>D No 1000Genomes
tmp_4_8849419_T_C 352 I>V No 1000Genomes
ENSVATH11793662 365 P>T No 1000Genomes
ENSVATH02843941 366 S>T No 1000Genomes
tmp_4_8849335_T_C 380 M>V No 1000Genomes
ENSVATH06677570 386 G>D No 1000Genomes
tmp_4_8849254_C_T 407 D>N No 1000Genomes
tmp_4_8849205_C_T 423 R>K No 1000Genomes
ENSVATH00508130 429 E>Q No 1000Genomes
tmp_4_8849182_C_T 431 A>T No 1000Genomes
ENSVATH06677565 456 E>D No 1000Genomes
ENSVATH02843933 457 A>G No 1000Genomes
tmp_4_8849097_G_A 459 A>V No 1000Genomes
tmp_4_8849094_G_T 460 A>E No 1000Genomes
ENSVATH14205641 466 S>L No 1000Genomes
tmp_4_8849077_A_T 466 S>T No 1000Genomes
tmp_4_8849067_T_A 469 K>M No 1000Genomes
ENSVATH00508127 469 K>N No 1000Genomes
ENSVATH11793661 470 N>Y No 1000Genomes
ENSVATH06677563 474 F>L No 1000Genomes
tmp_4_8849029_C_T 482 V>I No 1000Genomes
ENSVATH02843932 483 T>S No 1000Genomes
ENSVATH02843931 485 T>A No 1000Genomes
ENSVATH02843930 485 T>I No 1000Genomes
ENSVATH02843929 486 K>R No 1000Genomes
ENSVATH02843928 487 D>E No 1000Genomes
tmp_4_8849013_T_C 487 D>G No 1000Genomes
tmp_4_8849008_C_T 489 G>R No 1000Genomes
ENSVATH15362409 490 Y>* No 1000Genomes

No associated diseases with Q5XF20

1 regional properties for Q5XF20

Type Name Position InterPro Accession
conserved_site UDP-glycosyltransferase family, conserved site 357 - 400 IPR035595

Functions

Description
EC Number 2.4.1.120 Hexosyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

6 GO annotations of molecular function

Name Definition
cinnamate beta-D-glucosyltransferase activity Catalysis of the reaction: trans-cinnamate + UDP-D-glucose = 1-O-trans-cinnamoyl-beta-D-glucopyranose + UDP.
hydroxycinnamate 4-beta-glucosyltransferase activity Catalysis of the reaction: 4-coumarate + UDP-D-glucose = 4-O-beta-D-glucosyl-4-hydroxycinnamate + UDP.
quercetin 3-O-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule.
quercetin 7-O-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule.
sinapate 1-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose.
UDP-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule.

2 GO annotations of biological process

Name Definition
response to toxic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
response to UV-B Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.

36 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q1LZI1 UGT3A1 UDP-glucuronosyltransferase 3A1 Bos taurus (Bovine) PR
P36537 UGT2B10 UDP-glucuronosyltransferase 2B10 Homo sapiens (Human) PR
Q3SY77 UGT3A2 UDP-glucuronosyltransferase 3A2 Homo sapiens (Human) PR
O75310 UGT2B11 UDP-glucuronosyltransferase 2B11 Homo sapiens (Human) PR
P16662 UGT2B7 UDP-glucuronosyltransferase 2B7 Homo sapiens (Human) PR
Q16880 UGT8 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Homo sapiens (Human) PR
Q64676 Ugt8 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Mus musculus (Mouse) PR
Q8JZZ0 Ugt3a2 UDP-glucuronosyltransferase 3A2 Mus musculus (Mouse) PR
Q09426 Ugt8 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Rattus norvegicus (Rat) PR
Q22295 ugt-50 Putative UDP-glucuronosyltransferase ugt-50 Caenorhabditis elegans PR
Q9FE68 UGT71C5 UDP-glycosyltransferase 71C5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LML6 UGT71C4 Flavonol 3-O-glucosyltransferase UGT71C4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LML7 UGT71C3 UDP-glycosyltransferase 71C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQG4 UGT73B5 UDP-glycosyltransferase 73B5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZVX4 UGT90A1 UDP-glycosyltransferase 90A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ98 UGT73C2 UDP-glycosyltransferase 73C2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ97 UGT73C4 UDP-glycosyltransferase 73C4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ96 UGT73C3 UDP-glycosyltransferase 73C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ95 UGT73C6 UDP-glycosyltransferase 73C6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ94 UGT73C5 UDP-glycosyltransferase 73C5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SJL0 UGT86A1 UDP-glycosyltransferase 86A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY9 UGT71B1 UDP-glycosyltransferase 71B1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY6 UGT71B6 UDP-glycosyltransferase 71B6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY5 UGT71B7 UDP-glycosyltransferase 71B7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY4 UGT71B8 UDP-glycosyltransferase 71B8 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LHJ2 UGT82A1 UDP-glycosyltransferase 82A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SCP5 UGT73C7 UDP-glycosyltransferase 73C7 Arabidopsis thaliana (Mouse-ear cress) PR
O23382 UGT71B5 UDP-glycosyltransferase 71B5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LXV0 UGT92A1 UDP-glycosyltransferase 92A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FN28 UGT79B9 UDP-glycosyltransferase 79B9 Arabidopsis thaliana (Mouse-ear cress) PR
O22822 UGT74F2 UDP-glycosyltransferase 74F2 Arabidopsis thaliana (Mouse-ear cress) PR
Q94AB5 UGT76E12 Flavonol 3-O-glucosyltransferase UGT76E12 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LME8 UGT85A7 UDP-glycosyltransferase 85A7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LMF1 UGT85A3 UDP-glycosyltransferase 85A3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LS16 UGT76E7 UDP-glycosyltransferase 76E7 Arabidopsis thaliana (Mouse-ear cress) PR
O48676 UGT74B1 UDP-glycosyltransferase 74B1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MGSISEMVFE TCPSPNPIHV MLVSFQGQGH VNPLLRLGKL IASKGLLVTF VTTELWGKKM
70 80 90 100 110 120
RQANKIVDGE LKPVGSGSIR FEFFDEEWAE DDDRRADFSL YIAHLESVGI REVSKLVRRY
130 140 150 160 170 180
EEANEPVSCL INNPFIPWVC HVAEEFNIPC AVLWVQSCAC FSAYYHYQDG SVSFPTETEP
190 200 210 220 230 240
ELDVKLPCVP VLKNDEIPSF LHPSSRFTGF RQAILGQFKN LSKSFCVLID SFDSLEQEVI
250 260 270 280 290 300
DYMSSLCPVK TVGPLFKVAR TVTSDVSGDI CKSTDKCLEW LDSRPKSSVV YISFGTVAYL
310 320 330 340 350 360
KQEQIEEIAH GVLKSGLSFL WVIRPPPHDL KVETHVLPQE LKESSAKGKG MIVDWCPQEQ
370 380 390 400 410 420
VLSHPSVACF VTHCGWNSTM ESLSSGVPVV CCPQWGDQVT DAVYLIDVFK TGVRLGRGAT
430 440 450 460 470 480
EERVVPREEV AEKLLEATVG EKAEELRKNA LKWKAEAEAA VAPGGSSDKN FREFVEKLGA
GVTKTKDNGY