Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FE68

Entry ID Method Resolution Chain Position Source
AF-Q9FE68-F1 Predicted AlphaFoldDB

36 variants for Q9FE68

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH10726966 9 V>A No 1000Genomes
tmp_1_2223922_C_A 12 P>T No 1000Genomes
ENSVATH00009868 17 L>I No 1000Genomes
tmp_1_2223992_C_A 35 S>Y No 1000Genomes
tmp_1_2224018_C_A 44 L>I No 1000Genomes
ENSVATH04533490 81 L>F No 1000Genomes
tmp_1_2224178_T_A 97 I>K No 1000Genomes
tmp_1_2224180_C_T 98 P>S No 1000Genomes
tmp_1_2224190_G_T 101 R>I No 1000Genomes
tmp_1_2224216_T_G 110 S>A No 1000Genomes
tmp_1_2224301_G_A 138 R>H No 1000Genomes
tmp_1_2224303_G_A 139 E>K No 1000Genomes
ENSVATH10726969 140 V>I No 1000Genomes
tmp_1_2224316_C_T 143 P>L No 1000Genomes
ENSVATH00009869 179 E>K No 1000Genomes
ENSVATH10726970 180 E>K No 1000Genomes
ENSVATH04533491 183 I>L No 1000Genomes
tmp_1_2224527_G_C 213 E>D No 1000Genomes
ENSVATH04533492 214 R>Q No 1000Genomes
tmp_1_2224545_G_T 219 K>N No 1000Genomes
tmp_1_2224568_C_T 227 T>I No 1000Genomes
ENSVATH04533493 229 V>M No 1000Genomes
ENSVATH04533494 240 G>R No 1000Genomes
ENSVATH10726971 251 P>L No 1000Genomes
ENSVATH04533495 261 P>S No 1000Genomes
tmp_1_2224672_G_A 262 G>S No 1000Genomes
ENSVATH00009871 262 G>V No 1000Genomes
ENSVATH00009872 307 E>V No 1000Genomes
tmp_1_2224860_T_G 324 D>E No 1000Genomes
ENSVATH13860147 329 E>D No 1000Genomes
ENSVATH04533497 338 R>Q No 1000Genomes
tmp_1_2224925_G_A 346 C>Y No 1000Genomes
ENSVATH13860148 356 A>T No 1000Genomes
tmp_1_2225168_A_C 427 D>A No 1000Genomes
ENSVATH04533500 443 V>M No 1000Genomes
ENSVATH00009873 452 S>T No 1000Genomes

No associated diseases with Q9FE68

5 regional properties for Q9FE68

Type Name Position InterPro Accession
conserved_site TPP-binding enzyme, conserved site 506 - 525 IPR000399
domain Thiamine pyrophosphate enzyme, TPP-binding 469 - 624 IPR011766
domain Thiamine pyrophosphate enzyme, central domain 276 - 405 IPR012000
domain Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain 83 - 246 IPR012001
domain Acetolactate synthase large subunit, TPP binding domain 447 - 639 IPR039368

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

2 GO annotations of molecular function

Name Definition
abscisic acid glucosyltransferase activity Catalysis of the reaction: (+)-abscisate + UDP-D-glucose = abscisic acid glucose ester + UDP.
quercetin 3-O-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule.

4 GO annotations of biological process

Name Definition
abscisic acid homeostasis Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell.
abscisic acid metabolic process The chemical reactions and pathways involving abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.
drought recovery Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition.
positive regulation of seed germination Any process that activates or increase the rate of seed germination.

36 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q1LZI1 UGT3A1 UDP-glucuronosyltransferase 3A1 Bos taurus (Bovine) PR
P36537 UGT2B10 UDP-glucuronosyltransferase 2B10 Homo sapiens (Human) PR
Q3SY77 UGT3A2 UDP-glucuronosyltransferase 3A2 Homo sapiens (Human) PR
O75310 UGT2B11 UDP-glucuronosyltransferase 2B11 Homo sapiens (Human) PR
P16662 UGT2B7 UDP-glucuronosyltransferase 2B7 Homo sapiens (Human) PR
Q16880 UGT8 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Homo sapiens (Human) PR
Q64676 Ugt8 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Mus musculus (Mouse) PR
Q8JZZ0 Ugt3a2 UDP-glucuronosyltransferase 3A2 Mus musculus (Mouse) PR
Q09426 Ugt8 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Rattus norvegicus (Rat) PR
Q22295 ugt-50 Putative UDP-glucuronosyltransferase ugt-50 Caenorhabditis elegans PR
Q9LME8 UGT85A7 UDP-glycosyltransferase 85A7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LMF1 UGT85A3 UDP-glycosyltransferase 85A3 Arabidopsis thaliana (Mouse-ear cress) PR
O48676 UGT74B1 UDP-glycosyltransferase 74B1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZVX4 UGT90A1 UDP-glycosyltransferase 90A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ98 UGT73C2 UDP-glycosyltransferase 73C2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ97 UGT73C4 UDP-glycosyltransferase 73C4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ96 UGT73C3 UDP-glycosyltransferase 73C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ95 UGT73C6 UDP-glycosyltransferase 73C6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ94 UGT73C5 UDP-glycosyltransferase 73C5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SJL0 UGT86A1 UDP-glycosyltransferase 86A1 Arabidopsis thaliana (Mouse-ear cress) PR
O22822 UGT74F2 UDP-glycosyltransferase 74F2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LHJ2 UGT82A1 UDP-glycosyltransferase 82A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q94AB5 UGT76E12 Flavonol 3-O-glucosyltransferase UGT76E12 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SCP5 UGT73C7 UDP-glycosyltransferase 73C7 Arabidopsis thaliana (Mouse-ear cress) PR
Q5XF20 UGT84A1 UDP-glycosyltransferase 84A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LS16 UGT76E7 UDP-glycosyltransferase 76E7 Arabidopsis thaliana (Mouse-ear cress) PR
O23382 UGT71B5 UDP-glycosyltransferase 71B5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FN28 UGT79B9 UDP-glycosyltransferase 79B9 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LML6 UGT71C4 Flavonol 3-O-glucosyltransferase UGT71C4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LML7 UGT71C3 UDP-glycosyltransferase 71C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY4 UGT71B8 UDP-glycosyltransferase 71B8 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY5 UGT71B7 UDP-glycosyltransferase 71B7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY6 UGT71B6 UDP-glycosyltransferase 71B6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY9 UGT71B1 UDP-glycosyltransferase 71B1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LXV0 UGT92A1 UDP-glycosyltransferase 92A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQG4 UGT73B5 UDP-glycosyltransferase 73B5 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MKTAELIFVP LPETGHLLST IEFGKRLLNL DRRISMITIL SMNLPYAPHA DASLASLTAS
70 80 90 100 110 120
EPGIRIISLP EIHDPPPIKL LDTSSETYIL DFIHKNIPCL RKTIQDLVSS SSSSGGGSSH
130 140 150 160 170 180
VAGLILDFFC VGLIDIGREV NLPSYIFMTS NFGFLGVLQY LPERQRLTPS EFDESSGEEE
190 200 210 220 230 240
LHIPAFVNRV PAKVLPPGVF DKLSYGSLVK IGERLHEAKG ILVNSFTQVE PYAAEHFSQG
250 260 270 280 290 300
RDYPHVYPVG PVLNLTGRTN PGLASAQYKE MMKWLDEQPD SSVLFLCFGS MGVFPAPQIT
310 320 330 340 350 360
EIAHALELIG CRFIWAIRTN MAGDGDPQEP LPEGFVDRTM GRGIVCSWAP QVDILAHKAT
370 380 390 400 410 420
GGFVSHCGWN SVQESLWYGV PIATWPMYAE QQLNAFEMVK ELGLAVEIRL DYVADGDRVT
430 440 450 460 470
LEIVSADEIA TAVRSLMDSD NPVRKKVIEK SSVARKAVGD GGSSTVATCN FIKDILGDHF