Q9LME8

PR
Gene name
UGT85A7 (At1g22340, T16E15.5)
Protein name
UDP-glycosyltransferase 85A7
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G22340
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

412-485 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LME8

Entry ID Method Resolution Chain Position Source
AF-Q9LME8-F1 Predicted AlphaFoldDB

61 variants for Q9LME8

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_7892071_T_C 7 H>R No 1000Genomes
ENSVATH04622663 14 V>I No 1000Genomes
ENSVATH11784890 25 I>T No 1000Genomes
tmp_1_7891958_C_A 45 V>F No 1000Genomes
ENSVATH11784889 48 L>V No 1000Genomes
ENSVATH11784888 54 L>I No 1000Genomes
ENSVATH00037349 62 A>V No 1000Genomes
tmp_1_7891895_A_G 66 F>L No 1000Genomes
ENSVATH11784887 70 R>W No 1000Genomes
tmp_1_7891875_C_G 72 E>D No 1000Genomes
tmp_1_7891855_G_T 79 P>Q No 1000Genomes
tmp_1_7891850_T_C 81 T>A No 1000Genomes
ENSVATH00037347 82 D>Y No 1000Genomes
ENSVATH04622662 87 Q>* No 1000Genomes
ENSVATH11784844 96 I>T No 1000Genomes
ENSVATH11784843 97 E>K No 1000Genomes
ENSVATH00037346 100 C>S No 1000Genomes
ENSVATH00037346 100 C>Y No 1000Genomes
ENSVATH11784841 107 I>L No 1000Genomes
ENSVATH11784840 110 R>L No 1000Genomes
ENSVATH04622658 114 K>R No 1000Genomes
tmp_1_7891748_C_A,G 115 D>H No 1000Genomes
tmp_1_7891748_C_A,G 115 D>Y No 1000Genomes
tmp_1_7891702_C_T 130 S>N No 1000Genomes
ENSVATH01087525 149 N>S No 1000Genomes
ENSVATH13944325 153 G>S No 1000Genomes
ENSVATH04622656 157 I>V No 1000Genomes
tmp_1_7891392_T_A 179 K>M No 1000Genomes
tmp_1_7891341_C_T 196 R>K No 1000Genomes
ENSVATH11784627 224 S>F No 1000Genomes
ENSVATH04622653 227 A>T No 1000Genomes
ENSVATH00037344 247 Q>R No 1000Genomes
ENSVATH01087521 252 P>S No 1000Genomes
ENSVATH00037343 269 E>D No 1000Genomes
ENSVATH00037342 271 S>R No 1000Genomes
ENSVATH04622652 291 L>F No 1000Genomes
ENSVATH04622650 300 L>V No 1000Genomes
ENSVATH11784625 303 N>S No 1000Genomes
ENSVATH04622649 310 M>I No 1000Genomes
ENSVATH04622648 312 A>E No 1000Genomes
tmp_1_7890988_G_C 314 Q>E No 1000Genomes
tmp_1_7890984_A_T 315 L>H No 1000Genomes
ENSVATH11784524 316 E>G No 1000Genomes
tmp_1_7890972_G_C 319 A>G No 1000Genomes
tmp_1_7890960_G_C 323 A>G No 1000Genomes
tmp_1_7890937_A_C 331 W>G No 1000Genomes
ENSVATH01087520 333 I>V No 1000Genomes
ENSVATH04622645 341 E>V No 1000Genomes
tmp_1_7890854_T_A 358 R>S No 1000Genomes
tmp_1_7890823_C_A 369 V>F No 1000Genomes
ENSVATH04622642 374 A>V No 1000Genomes
tmp_1_7890745_C_T 395 V>I No 1000Genomes
tmp_1_7890737_C_T 397 M>I No 1000Genomes
ENSVATH04622639 457 R>Q No 1000Genomes
ENSVATH13944289 465 Y>* No 1000Genomes
tmp_1_7890526_C_T 468 G>S No 1000Genomes
ENSVATH00037339 469 S>P No 1000Genomes
ENSVATH00037338 475 E>G No 1000Genomes
tmp_1_7890493_G_A 479 H>Y No 1000Genomes
ENSVATH01087519 482 F>L No 1000Genomes
ENSVATH04622638 488 R>G No 1000Genomes

No associated diseases with Q9LME8

1 regional properties for Q9LME8

Type Name Position InterPro Accession
conserved_site UDP-glycosyltransferase family, conserved site 363 - 406 IPR035595

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
glucuronosyltransferase activity Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.
quercetin 3-O-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule.
quercetin 7-O-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

36 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q1LZI1 UGT3A1 UDP-glucuronosyltransferase 3A1 Bos taurus (Bovine) PR
P36537 UGT2B10 UDP-glucuronosyltransferase 2B10 Homo sapiens (Human) PR
Q3SY77 UGT3A2 UDP-glucuronosyltransferase 3A2 Homo sapiens (Human) PR
O75310 UGT2B11 UDP-glucuronosyltransferase 2B11 Homo sapiens (Human) PR
P16662 UGT2B7 UDP-glucuronosyltransferase 2B7 Homo sapiens (Human) PR
Q16880 UGT8 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Homo sapiens (Human) PR
Q64676 Ugt8 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Mus musculus (Mouse) PR
Q8JZZ0 Ugt3a2 UDP-glucuronosyltransferase 3A2 Mus musculus (Mouse) PR
Q09426 Ugt8 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Rattus norvegicus (Rat) PR
Q22295 ugt-50 Putative UDP-glucuronosyltransferase ugt-50 Caenorhabditis elegans PR
Q9FE68 UGT71C5 UDP-glycosyltransferase 71C5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LML6 UGT71C4 Flavonol 3-O-glucosyltransferase UGT71C4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LML7 UGT71C3 UDP-glycosyltransferase 71C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQG4 UGT73B5 UDP-glycosyltransferase 73B5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZVX4 UGT90A1 UDP-glycosyltransferase 90A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ98 UGT73C2 UDP-glycosyltransferase 73C2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ97 UGT73C4 UDP-glycosyltransferase 73C4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ96 UGT73C3 UDP-glycosyltransferase 73C3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ95 UGT73C6 UDP-glycosyltransferase 73C6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZQ94 UGT73C5 UDP-glycosyltransferase 73C5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SJL0 UGT86A1 UDP-glycosyltransferase 86A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY9 UGT71B1 UDP-glycosyltransferase 71B1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY6 UGT71B6 UDP-glycosyltransferase 71B6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY5 UGT71B7 UDP-glycosyltransferase 71B7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSY4 UGT71B8 UDP-glycosyltransferase 71B8 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LHJ2 UGT82A1 UDP-glycosyltransferase 82A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SCP5 UGT73C7 UDP-glycosyltransferase 73C7 Arabidopsis thaliana (Mouse-ear cress) PR
O23382 UGT71B5 UDP-glycosyltransferase 71B5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LXV0 UGT92A1 UDP-glycosyltransferase 92A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FN28 UGT79B9 UDP-glycosyltransferase 79B9 Arabidopsis thaliana (Mouse-ear cress) PR
O22822 UGT74F2 UDP-glycosyltransferase 74F2 Arabidopsis thaliana (Mouse-ear cress) PR
Q5XF20 UGT84A1 UDP-glycosyltransferase 84A1 Arabidopsis thaliana (Mouse-ear cress) PR
Q94AB5 UGT76E12 Flavonol 3-O-glucosyltransferase UGT76E12 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LMF1 UGT85A3 UDP-glycosyltransferase 85A3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LS16 UGT76E7 UDP-glycosyltransferase 76E7 Arabidopsis thaliana (Mouse-ear cress) PR
O48676 UGT74B1 UDP-glycosyltransferase 74B1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MESHVVHNAQ KPHVVCVPYP AQGHINPMLK VAKLLYAKGF HVTFVNTLYN HNRLLRSRGP
70 80 90 100 110 120
NALDGFPSFR FESIPDGLPE TDGDRTQHTP TVCMSIEKNC LAPFKEILRR INDKDDVPPV
130 140 150 160 170 180
SCIVSDGVMS FTLDAAEELG VPEVIFWTNS ACGFMTILHF YLFIEKGLSP FKDESYMSKE
190 200 210 220 230 240
HLDTVIDWIP SMKNLRLKDI PSYIRTTNPD NIMLNFLIRE VERSKRASAI ILNTFDELEH
250 260 270 280 290 300
DVIQSMQSIL PPVYSIGPLH LLVKEEINEA SEIGQMGLNL WREEMECLDW LDTKTPNSVL
310 320 330 340 350 360
FVNFGCITVM SAKQLEEFAW GLAASRKEFL WVIRPNLVVG EAMVVLPQEF LAETIDRRML
370 380 390 400 410 420
ASWCPQEKVL SHPAIGGFLT HCGWNSTLES LAGGVPMICW PCFSEQPTNC KFCCDEWGVG
430 440 450 460 470 480
IEIGKDVKRE EVETVVRELM DGEKGKKLRE KAEEWRRLAE EATRYKHGSS VMNLETLIHK
VFLENLR