Q9SIW3

PR
Gene name
SFH7 (At2g16380, F16F14.12)
Protein name
Phosphatidylinositol/phosphatidylcholine transfer protein SFH7
Names
Protein SEC FOURTEEN HOMOLOGS 7, AtSFH7
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G16380
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-93 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SIW3

Entry ID Method Resolution Chain Position Source
AF-Q9SIW3-F1 Predicted AlphaFoldDB

43 variants for Q9SIW3

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_7086099_G_T 12 E>D No 1000Genomes
tmp_2_7086104_G_C 14 G>A No 1000Genomes
tmp_2_7086123_G_T 20 M>I No 1000Genomes
tmp_2_7086125_G_A 21 S>N No 1000Genomes
ENSVATH05499065 52 V>L No 1000Genomes
ENSVATH05499066 56 D>E No 1000Genomes
ENSVATH05499067 57 D>N No 1000Genomes
ENSVATH05499068 61 D>E No 1000Genomes
ENSVATH00232210 68 A>G No 1000Genomes
ENSVATH13201019 71 Q>L No 1000Genomes
ENSVATH13201077 107 W>* No 1000Genomes
tmp_2_7086899_T_A 125 D>E No 1000Genomes
tmp_2_7086927_C_G 135 L>V No 1000Genomes
ENSVATH05499086 148 E>D No 1000Genomes
tmp_2_7087035_A_T 171 M>L No 1000Genomes
tmp_2_7087108_C_T 195 A>V No 1000Genomes
tmp_2_7087447_G_A 252 G>R No 1000Genomes
ENSVATH00232214 260 I>V No 1000Genomes
ENSVATH01815823 303 A>E No 1000Genomes
ENSVATH05499101 306 G>D No 1000Genomes
tmp_2_7087738_G_A 318 D>N No 1000Genomes
ENSVATH05499109 363 T>S No 1000Genomes
ENSVATH01815838 365 E>G No 1000Genomes
ENSVATH01815837 365 E>K No 1000Genomes
tmp_2_7088052_T_C 368 V>A No 1000Genomes
ENSVATH13201118 386 P>T No 1000Genomes
tmp_2_7088118_T_A 390 L>* No 1000Genomes
ENSVATH10103905 390 L>F No 1000Genomes
ENSVATH05499110 400 Q>R No 1000Genomes
ENSVATH01815846 408 V>L No 1000Genomes
ENSVATH00232217 427 A>D No 1000Genomes
ENSVATH05499111 430 R>T No 1000Genomes
ENSVATH00232219 435 V>A No 1000Genomes
ENSVATH01815848 439 T>S No 1000Genomes
ENSVATH05499112 454 Q>K No 1000Genomes
ENSVATH01815853 456 E>D No 1000Genomes
tmp_2_7088410_A_G 456 E>G No 1000Genomes
tmp_2_7088496_G_C 485 D>H No 1000Genomes
ENSVATH05499113 488 S>L No 1000Genomes
ENSVATH00232220 502 A>T No 1000Genomes
ENSVATH13201120 503 L>V No 1000Genomes
tmp_2_7088568_C_G 509 L>V No 1000Genomes
tmp_2_7088574_C_A 511 H>N No 1000Genomes

No associated diseases with Q9SIW3

2 regional properties for Q9SIW3

Type Name Position InterPro Accession
domain CRAL-TRIO lipid binding domain 130 - 304 IPR001251
domain CRAL/TRIO, N-terminal domain 85 - 110 IPR011074

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Peripheral membrane protein
  • Cell membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

27 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5SYC1 CLVS2 Clavesin-2 Homo sapiens (Human) PR
Q9BTX7 TTPAL Alpha-tocopherol transfer protein-like Homo sapiens (Human) PR
Q92503 SEC14L1 SEC14-like protein 1 Homo sapiens (Human) PR
Q8IUQ0 CLVS1 Clavesin-1 Homo sapiens (Human) PR
Q9UDX3 SEC14L4 SEC14-like protein 4 Homo sapiens (Human) PR
B5MCN3 SEC14L6 Putative SEC14-like protein 6 Homo sapiens (Human) PR
Q8BG92 Clvs2 Clavesin-2 Mus musculus (Mouse) PR
Q9D4C9 Clvs1 Clavesin-1 Mus musculus (Mouse) PR
Q9D3D0 Ttpal Alpha-tocopherol transfer protein-like Mus musculus (Mouse) PR
Q8R0F9 Sec14l4 SEC14-like protein 4 Mus musculus (Mouse) PR
A6JFQ6 Clvs1 Clavesin-1 Rattus norvegicus (Rat) PR
A6JUQ6 Clvs2 Clavesin-2 Rattus norvegicus (Rat) PR
Q09270 C34C12.6 CRAL-TRIO domain-containing protein C34C12.6 Caenorhabditis elegans PR
Q56ZI2 PATL2 Patellin-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q94C59 PATL4 Patellin-4 Arabidopsis thaliana (Mouse-ear cress) PR
Q56WK6 PATL1 Patellin-1 Arabidopsis thaliana (Mouse-ear cress) PR
Q56Z59 PATL3 Patellin-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M0R2 PATL5 Patellin-5 Arabidopsis thaliana (Mouse-ear cress) PR
F4J7S8 SFH9 Phosphatidylinositol/phosphatidylcholine transfer protein SFH9 Arabidopsis thaliana (Mouse-ear cress) PR
Q94A34 SFH12 Phosphatidylinositol/phosphatidylcholine transfer protein SFH12 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SI13 SFH10 Phosphatidylinositol/phosphatidylcholine transfer protein SFH10 Arabidopsis thaliana (Mouse-ear cress) PR
F4IHJ0 SFH8 Phosphatidylinositol/phosphatidylcholine transfer protein SFH8 Arabidopsis thaliana (Mouse-ear cress) PR
F4JVA6 SFH6 Phosphatidylinositol/phosphatidylcholine transfer protein SFH6 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GXC6 SFH5 Phosphatidylinositol/phosphatidylcholine transfer protein SFH5 Arabidopsis thaliana (Mouse-ear cress) PR
Q93ZE9 SFH3 Phosphatidylinositol/phosphatidylcholine transfer protein SFH3 Arabidopsis thaliana (Mouse-ear cress) PR
Q501H5 SFH13 Phosphatidylinositol/phosphatidylcholine transfer protein SFH13 Arabidopsis thaliana (Mouse-ear cress) PR
Q5SPP0 clvs2 Clavesin-2 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MADTKQDMEN SEDGRKLVKM SSLKQKAISA SNRFKNSFKK KTRRTSSKIV SVANTDDING
70 80 90 100 110 120
DDYLSVEAFR QVLVLDDLLP PKHDDLHMML RFLRARKFDK EKAKQMWSDM LQWRMDFGVD
130 140 150 160 170 180
TIIEDFEFEE IDQVLKHYPQ GYHGVDKEGR PVYIERLGQI DANKLLQATT MDRYEKYHVK
190 200 210 220 230 240
EFEKMFKIKF PSCSAAAKKH IDQSTTIFDV QGVGLKNFNK SARELLQRLL KIDNDNYPET
250 260 270 280 290 300
LNRMFIINAG PGFRLLWAPI KKFLDPKTTS KIHVLGNKYQ PKLLEAIDAS ELPYFFGGLC
310 320 330 340 350 360
TCADKGGCLR SDKGPWNDPE LLKIARNPEA RFSTISEEDY LLVEEGTSMS MVFEPLERNK
370 380 390 400 410 420
MKTIEENVSE KHIDAVDKFM ALSLPPKPHL KTLRKGKEPQ KKDDSFLVGG VIAFVMGIVA
430 440 450 460 470 480
MLRLSKAVPR KLTDVALLTN SVYYEEAKMS KPNQDEVSAP PVSSSEYVIM VKRMAELEEK
490 500 510 520 530 540
YKSLDSKSAD EALEKDDKLQ AALNRVQVLE HELSETKKAL DETMVNQQGI LAYIEKKNKK
KRMFFRF