Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q56WK6

Entry ID Method Resolution Chain Position Source
AF-Q56WK6-F1 Predicted AlphaFoldDB

41 variants for Q56WK6

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH05130197 9 S>P No 1000Genomes
tmp_1_27148600_G_C 15 A>P No 1000Genomes
ENSVATH00138701 19 K>T No 1000Genomes
tmp_1_27148639_G_A 28 V>I No 1000Genomes
tmp_1_27148690_T_C 45 S>P No 1000Genomes
ENSVATH01524309 60 E>D No 1000Genomes
ENSVATH00138702 71 S>P No 1000Genomes
ENSVATH13795941 79 V>I No 1000Genomes
ENSVATH13795942 103 L>R No 1000Genomes
ENSVATH13795943 109 N>D No 1000Genomes
ENSVATH01524313 120 V>A No 1000Genomes
ENSVATH00138704 120 V>L No 1000Genomes
ENSVATH14471722 122 E>D No 1000Genomes
ENSVATH01524314 125 T>P No 1000Genomes
ENSVATH01524315 133 E>G No 1000Genomes
ENSVATH01524316 136 E>G No 1000Genomes
ENSVATH01524317 138 E>V No 1000Genomes
tmp_1_27149009_T_A 151 V>D No 1000Genomes
ENSVATH01524318 158 P>L No 1000Genomes
ENSVATH05130202 160 V>I No 1000Genomes
ENSVATH01524319 163 A>P No 1000Genomes
ENSVATH01524320 164 E>A No 1000Genomes
tmp_1_27149059_T_G 168 S>A No 1000Genomes
ENSVATH14471724 170 E>D No 1000Genomes
tmp_1_27149075_C_T 173 P>L No 1000Genomes
ENSVATH13795949 177 K>N No 1000Genomes
tmp_1_27149130_G_T 191 E>D No 1000Genomes
ENSVATH13795950 220 A>V No 1000Genomes
ENSVATH13795951 227 E>D No 1000Genomes
ENSVATH05130204 231 V>I No 1000Genomes
tmp_1_27149275_G_T 240 E>* No 1000Genomes
tmp_1_27149299_C_T 248 P>S No 1000Genomes
ENSVATH13795953 275 T>A No 1000Genomes
tmp_1_27149435_T_G 293 V>G No 1000Genomes
tmp_1_27149585_G_A 343 S>N No 1000Genomes
ENSVATH14471745 355 A>T No 1000Genomes
tmp_1_27150044_G_A 433 S>N No 1000Genomes
tmp_1_27150275_C_G 481 P>A No 1000Genomes
tmp_1_27150455_A_C 509 S>R No 1000Genomes
ENSVATH13795957 517 T>I No 1000Genomes
tmp_1_27150516_C_T 529 T>I No 1000Genomes

No associated diseases with Q56WK6

3 regional properties for Q56WK6

Type Name Position InterPro Accession
domain CRAL-TRIO lipid binding domain 295 - 468 IPR001251
domain GOLD domain 471 - 572 IPR009038
domain CRAL/TRIO, N-terminal domain 240 - 280 IPR011074

Functions

Description
EC Number
Subcellular Localization
  • Membrane
  • Cytoplasm
  • Mainly membrane-associated
  • Also cytoplasmic
  • Cell plate during cell division
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
apoplast The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
plasmodesma A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
vacuole A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

3 GO annotations of molecular function

Name Definition
lipid binding Binding to a lipid.
protease binding Binding to a protease or a peptidase.
salicylic acid binding Binding to salicylic acid.

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
pollen tube growth Growth of pollen via tip extension of the intine wall.

26 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5SYC1 CLVS2 Clavesin-2 Homo sapiens (Human) PR
Q9BTX7 TTPAL Alpha-tocopherol transfer protein-like Homo sapiens (Human) PR
Q92503 SEC14L1 SEC14-like protein 1 Homo sapiens (Human) PR
Q8IUQ0 CLVS1 Clavesin-1 Homo sapiens (Human) PR
Q9UDX3 SEC14L4 SEC14-like protein 4 Homo sapiens (Human) PR
B5MCN3 SEC14L6 Putative SEC14-like protein 6 Homo sapiens (Human) PR
Q8BG92 Clvs2 Clavesin-2 Mus musculus (Mouse) PR
Q9D4C9 Clvs1 Clavesin-1 Mus musculus (Mouse) PR
Q9D3D0 Ttpal Alpha-tocopherol transfer protein-like Mus musculus (Mouse) PR
Q8R0F9 Sec14l4 SEC14-like protein 4 Mus musculus (Mouse) PR
A6JFQ6 Clvs1 Clavesin-1 Rattus norvegicus (Rat) PR
A6JUQ6 Clvs2 Clavesin-2 Rattus norvegicus (Rat) PR
Q09270 C34C12.6 CRAL-TRIO domain-containing protein C34C12.6 Caenorhabditis elegans PR
Q8GXC6 SFH5 Phosphatidylinositol/phosphatidylcholine transfer protein SFH5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SIW3 SFH7 Phosphatidylinositol/phosphatidylcholine transfer protein SFH7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SI13 SFH10 Phosphatidylinositol/phosphatidylcholine transfer protein SFH10 Arabidopsis thaliana (Mouse-ear cress) PR
F4IHJ0 SFH8 Phosphatidylinositol/phosphatidylcholine transfer protein SFH8 Arabidopsis thaliana (Mouse-ear cress) PR
Q93ZE9 SFH3 Phosphatidylinositol/phosphatidylcholine transfer protein SFH3 Arabidopsis thaliana (Mouse-ear cress) PR
F4J7S8 SFH9 Phosphatidylinositol/phosphatidylcholine transfer protein SFH9 Arabidopsis thaliana (Mouse-ear cress) PR
Q94A34 SFH12 Phosphatidylinositol/phosphatidylcholine transfer protein SFH12 Arabidopsis thaliana (Mouse-ear cress) PR
F4JVA6 SFH6 Phosphatidylinositol/phosphatidylcholine transfer protein SFH6 Arabidopsis thaliana (Mouse-ear cress) PR
Q56Z59 PATL3 Patellin-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q56ZI2 PATL2 Patellin-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q94C59 PATL4 Patellin-4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M0R2 PATL5 Patellin-5 Arabidopsis thaliana (Mouse-ear cress) PR
Q5SPP0 clvs2 Clavesin-2 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MAQEEVQKSA DVAAAPVVKE KPITDKEVTI PTPVAEKEEV AAPVSDEKAV PEKEVTPEKE
70 80 90 100 110 120
APAAEAEKSV SVKEEETVVV AEKVVVLTAE EVQKKALEEF KELVREALNK REFTAPVTPV
130 140 150 160 170 180
KEEKTEEKKT EEETKEEEKT EEKKEETTTE VKVEEEKPAV PAAEEEKSSE AAPVETKSEE
190 200 210 220 230 240
KPEEKAEVTT EKASSAEEDG TKTVEAIEES IVSVSPPESA VAPVVVETVA VAEAEPVEPE
250 260 270 280 290 300
EVSIWGVPLL QDERSDVILT KFLRARDFKV KEALTMLKNT VQWRKENKID ELVESGEEVS
310 320 330 340 350 360
EFEKMVFAHG VDKEGHVVIY SSYGEFQNKE LFSDKEKLNK FLSWRIQLQE KCVRAIDFSN
370 380 390 400 410 420
PEAKSSFVFV SDFRNAPGLG KRALWQFIRR AVKQFEDNYP EFAAKELFIN VPWWYIPYYK
430 440 450 460 470 480
TFGSIITSPR TRSKMVLAGP SKSADTIFKY IAPEQVPVKY GGLSKDTPLT EETITEAIVK
490 500 510 520 530 540
PAANYTIELP ASEACTLSWE LRVLGADVSY GAQFEPTTEG SYAVIVSKTR KIGSTDEPVI
550 560 570
TDSFKVGEPG KIVITIDNQT SKKKKVLYRF KTQ