Q9SI13

PR
Gene name
SFH10 (At2g18180, F8D23.4)
Protein name
Phosphatidylinositol/phosphatidylcholine transfer protein SFH10
Names
Protein SEC FOURTEEN HOMOLOGS 10, AtSFH10
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G18180
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-77 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SI13

Entry ID Method Resolution Chain Position Source
AF-Q9SI13-F1 Predicted AlphaFoldDB

62 variants for Q9SI13

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH00236157 6 D>G No 1000Genomes
ENSVATH05521696 43 S>Y No 1000Genomes
ENSVATH00236154 53 A>V No 1000Genomes
ENSVATH05521695 58 V>A No 1000Genomes
ENSVATH00236152 65 V>A No 1000Genomes
ENSVATH05521694 65 V>L No 1000Genomes
tmp_2_7913253_A_G 91 F>L No 1000Genomes
tmp_2_7913243_T_G 94 E>A No 1000Genomes
ENSVATH13256753 105 R>G No 1000Genomes
ENSVATH00236151 112 A>V No 1000Genomes
ENSVATH05521689 127 V>L No 1000Genomes
ENSVATH05521688 135 H>Y No 1000Genomes
tmp_2_7912997_C_T 145 V>M No 1000Genomes
tmp_2_7912908_C_G 174 E>D No 1000Genomes
ENSVATH14514134 215 A>V No 1000Genomes
ENSVATH05521685 220 T>M No 1000Genomes
ENSVATH01834995 221 R>H No 1000Genomes
ENSVATH05521684 231 P>S No 1000Genomes
ENSVATH05521682 235 N>D No 1000Genomes
ENSVATH13256730 236 R>M No 1000Genomes
tmp_2_7912507_C_G 250 W>C No 1000Genomes
ENSVATH13256728 294 T>P No 1000Genomes
ENSVATH13256726 302 M>T No 1000Genomes
ENSVATH01834986 306 K>E No 1000Genomes
tmp_2_7912150_A_G 314 I>T No 1000Genomes
tmp_2_7912151_T_C 314 I>V No 1000Genomes
tmp_2_7912027_T_C 319 N>S No 1000Genomes
ENSVATH05521666 337 N>K No 1000Genomes
tmp_2_7911964_G_A 340 S>F No 1000Genomes
ENSVATH14514131 347 V>D No 1000Genomes
tmp_2_7911938_C_A 349 E>* No 1000Genomes
ENSVATH00236144 353 T>A No 1000Genomes
tmp_2_7911902_A_T 361 C>S No 1000Genomes
tmp_2_7911825_C_A 365 V>L No 1000Genomes
ENSVATH00236143 368 H>P No 1000Genomes
ENSVATH05521665 371 W>R No 1000Genomes
ENSVATH00236142 386 V>I No 1000Genomes
ENSVATH05521661 417 T>A No 1000Genomes
tmp_2_7911558_T_G 422 T>P No 1000Genomes
tmp_2_7911550_G_C 424 N>K No 1000Genomes
ENSVATH05521660 438 P>L No 1000Genomes
tmp_2_7911507_C_T 439 V>I No 1000Genomes
ENSVATH00236137 454 K>N No 1000Genomes
ENSVATH00236136 455 K>N No 1000Genomes
ENSVATH01834984 458 T>I No 1000Genomes
tmp_2_7911443_G_A 460 T>I No 1000Genomes
ENSVATH05521656 475 E>K No 1000Genomes
tmp_2_7911380_G_C 481 T>R No 1000Genomes
tmp_2_7911378_T_C 482 N>D No 1000Genomes
ENSVATH00236135 482 N>K No 1000Genomes
ENSVATH00236134 484 S>N No 1000Genomes
ENSVATH14514130 485 A>G No 1000Genomes
ENSVATH14514129 487 P>Q No 1000Genomes
ENSVATH05521655 491 P>S No 1000Genomes
ENSVATH05521653 531 A>G No 1000Genomes
tmp_2_7911140_C_T 531 A>T No 1000Genomes
ENSVATH05521652 539 K>T No 1000Genomes
ENSVATH05521651 548 N>S No 1000Genomes
ENSVATH01834974 549 A>G No 1000Genomes
tmp_2_7911082_T_A 550 Y>F No 1000Genomes
ENSVATH05521649 553 N>K No 1000Genomes
ENSVATH05521650 553 N>S No 1000Genomes

No associated diseases with Q9SI13

2 regional properties for Q9SI13

Type Name Position InterPro Accession
domain CRAL-TRIO lipid binding domain 123 - 297 IPR001251
domain CRAL/TRIO, N-terminal domain 75 - 103 IPR011074

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Peripheral membrane protein
  • Cell membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

27 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5SYC1 CLVS2 Clavesin-2 Homo sapiens (Human) PR
Q9BTX7 TTPAL Alpha-tocopherol transfer protein-like Homo sapiens (Human) PR
Q92503 SEC14L1 SEC14-like protein 1 Homo sapiens (Human) PR
Q8IUQ0 CLVS1 Clavesin-1 Homo sapiens (Human) PR
Q9UDX3 SEC14L4 SEC14-like protein 4 Homo sapiens (Human) PR
B5MCN3 SEC14L6 Putative SEC14-like protein 6 Homo sapiens (Human) PR
Q8BG92 Clvs2 Clavesin-2 Mus musculus (Mouse) PR
Q9D4C9 Clvs1 Clavesin-1 Mus musculus (Mouse) PR
Q9D3D0 Ttpal Alpha-tocopherol transfer protein-like Mus musculus (Mouse) PR
Q8R0F9 Sec14l4 SEC14-like protein 4 Mus musculus (Mouse) PR
A6JFQ6 Clvs1 Clavesin-1 Rattus norvegicus (Rat) PR
A6JUQ6 Clvs2 Clavesin-2 Rattus norvegicus (Rat) PR
Q09270 C34C12.6 CRAL-TRIO domain-containing protein C34C12.6 Caenorhabditis elegans PR
Q56ZI2 PATL2 Patellin-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q94C59 PATL4 Patellin-4 Arabidopsis thaliana (Mouse-ear cress) PR
Q56WK6 PATL1 Patellin-1 Arabidopsis thaliana (Mouse-ear cress) PR
Q56Z59 PATL3 Patellin-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M0R2 PATL5 Patellin-5 Arabidopsis thaliana (Mouse-ear cress) PR
F4J7S8 SFH9 Phosphatidylinositol/phosphatidylcholine transfer protein SFH9 Arabidopsis thaliana (Mouse-ear cress) PR
Q94A34 SFH12 Phosphatidylinositol/phosphatidylcholine transfer protein SFH12 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SIW3 SFH7 Phosphatidylinositol/phosphatidylcholine transfer protein SFH7 Arabidopsis thaliana (Mouse-ear cress) PR
F4IHJ0 SFH8 Phosphatidylinositol/phosphatidylcholine transfer protein SFH8 Arabidopsis thaliana (Mouse-ear cress) PR
F4JVA6 SFH6 Phosphatidylinositol/phosphatidylcholine transfer protein SFH6 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GXC6 SFH5 Phosphatidylinositol/phosphatidylcholine transfer protein SFH5 Arabidopsis thaliana (Mouse-ear cress) PR
Q93ZE9 SFH3 Phosphatidylinositol/phosphatidylcholine transfer protein SFH3 Arabidopsis thaliana (Mouse-ear cress) PR
Q501H5 SFH13 Phosphatidylinositol/phosphatidylcholine transfer protein SFH13 Arabidopsis thaliana (Mouse-ear cress) PR
Q5SPP0 clvs2 Clavesin-2 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MSLNVDLDVC VLERPNVCSF KKRSCSKLSC SLTKKRRSSK VMSVEIFEDE HDAEELKVVD
70 80 90 100 110 120
AFRQVLILDE LLPDKHDDYH MMLRFLKARK FDLEKTNQMW SDMLRWRKEF GADTVMEDFE
130 140 150 160 170 180
FKEIDEVLKY YPQGHHGVDK EGRPVYIERL GQVDSTKLMQ VTTMDRYVNY HVMEFERTFN
190 200 210 220 230 240
VKFPACSIAA KKHIDQSTTI LDVQGVGLKN FNKAARDLIT RLQKVDGDNY PETLNRMFII
250 260 270 280 290 300
NAGSGFRMLW NTVKSFLDPK TTAKIHVLGN KYQSKLLEII DASELPEFLG GSCTCADNGG
310 320 330 340 350 360
CMRSDKGPWN NPDIMKRVNN GDHICSKRSQ ADNAGENIIS QGNNSAVEEA PETDQSQPSP
370 380 390 400 410 420
CQNVVVAHPA WNIPEAHKFS LSKRDVYAIQ EACKATNESG RSPIFTGVMA FVMGVVTMIR
430 440 450 460 470 480
VTKNVPRKLT ESTIYSSPVY CDENSMNKSS MHGKKMATTT ISGEDFMAVM KRMAELEQKV
490 500 510 520 530 540
TNLSAQPATM PPEKEEMLNA AISRADFLEQ ELAATKKALD DSLTRQEDLV AYVERKKKKK
550
KLVRFQINAY LTNFCFGV