Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9M0R2

Entry ID Method Resolution Chain Position Source
AF-Q9M0R2-F1 Predicted AlphaFoldDB

120 variants for Q9M0R2

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_4_5839765_C_T 2 S>F No 1000Genomes
ENSVATH06585210 8 T>S No 1000Genomes
tmp_4_5839795_C_T 12 P>L No 1000Genomes
ENSVATH02757938 28 P>Q No 1000Genomes
ENSVATH06585211 28 P>S No 1000Genomes
ENSVATH02757939 31 V>E No 1000Genomes
ENSVATH14103390 32 T>A No 1000Genomes
ENSVATH02757940 33 S>L No 1000Genomes
tmp_4_5839875_G_T 39 V>L No 1000Genomes
tmp_4_5839882_C_T 41 S>L No 1000Genomes
ENSVATH14103391 47 L>P No 1000Genomes
ENSVATH02757942 64 S>L No 1000Genomes
tmp_4_5839959_G_T 67 V>L No 1000Genomes
tmp_4_5839981_T_C 74 L>S No 1000Genomes
tmp_4_5839980_T_G 74 L>V No 1000Genomes
tmp_4_5839983_G_A 75 E>K No 1000Genomes
tmp_4_5839987_C_T 76 S>L No 1000Genomes
tmp_4_5839986_T_C 76 S>P No 1000Genomes
ENSVATH11355920 77 E>V No 1000Genomes
ENSVATH14103392 78 G>R No 1000Genomes
tmp_4_5839993_G_T 78 G>V No 1000Genomes
tmp_4_5839999_A_G 80 N>S No 1000Genomes
tmp_4_5840003_C_A 81 H>Q No 1000Genomes
tmp_4_5840004_G_A 82 A>T No 1000Genomes
tmp_4_5840007_G_A 83 A>T No 1000Genomes
ENSVATH06585212 84 E>K No 1000Genomes
ENSVATH02757943 87 E>K No 1000Genomes
tmp_4_5840022_C_G 88 Q>E No 1000Genomes
ENSVATH02757945 96 T>A No 1000Genomes
ENSVATH02757947 99 A>G No 1000Genomes
ENSVATH02757946 99 A>S No 1000Genomes
ENSVATH02757947 99 A>V No 1000Genomes
ENSVATH14103393 105 N>K No 1000Genomes
tmp_4_5840115_C_T 119 P>S No 1000Genomes
ENSVATH02757949 121 K>T No 1000Genomes
ENSVATH06585214 122 E>D No 1000Genomes
ENSVATH11355921 124 V>G No 1000Genomes
ENSVATH11355922 128 F>V No 1000Genomes
tmp_4_5840149_A_T 130 N>I No 1000Genomes
ENSVATH06585216 132 V>A No 1000Genomes
ENSVATH11355923 132 V>M No 1000Genomes
tmp_4_5840163_G_A 135 D>N No 1000Genomes
ENSVATH02757951 138 Q>H No 1000Genomes
tmp_4_5840178_C_T 140 H>Y No 1000Genomes
ENSVATH02757952 146 T>K No 1000Genomes
ENSVATH02757954 153 V>F No 1000Genomes
ENSVATH02757955 167 V>E No 1000Genomes
tmp_4_5840266_C_G 169 P>R No 1000Genomes
ENSVATH11355966 175 T>K No 1000Genomes
ENSVATH11355965 175 T>S No 1000Genomes
ENSVATH00481949 178 A>P No 1000Genomes
ENSVATH02757958 179 D>N No 1000Genomes
tmp_4_5840306_G_C 182 L>F No 1000Genomes
ENSVATH14103394 191 P>R No 1000Genomes
ENSVATH02757959 196 E>V No 1000Genomes
ENSVATH02757960 200 E>K No 1000Genomes
ENSVATH11355968 231 V>L No 1000Genomes
ENSVATH14103435 242 K>T No 1000Genomes
tmp_4_5840496_C_T 246 P>S No 1000Genomes
tmp_4_5840520_T_C 254 S>P No 1000Genomes
tmp_4_5840567_G_T 269 M>I No 1000Genomes
tmp_4_5840573_A_C 271 R>S No 1000Genomes
ENSVATH02757961 276 V>A No 1000Genomes
tmp_4_5840649_A_C 297 K>Q No 1000Genomes
ENSVATH00481951 316 L>P No 1000Genomes
tmp_4_5840734_C_G 325 T>S No 1000Genomes
ENSVATH00481952 332 L>F No 1000Genomes
ENSVATH06585219 336 D>E No 1000Genomes
tmp_4_5840769_A_G 337 R>G No 1000Genomes
tmp_4_5840773_C_A 338 T>N No 1000Genomes
tmp_4_5840775_G_A 339 D>N No 1000Genomes
ENSVATH06585220 340 V>I No 1000Genomes
tmp_4_5840781_G_A 341 V>I No 1000Genomes
tmp_4_5840786_G_T 342 L>F No 1000Genomes
tmp_4_5840785_T_G 342 L>W No 1000Genomes
ENSVATH00481953 343 L>V No 1000Genomes
tmp_4_5840800_G_A 347 R>K No 1000Genomes
ENSVATH11355970 355 E>K No 1000Genomes
tmp_4_5840824_A_T 355 E>V No 1000Genomes
ENSVATH00481954 365 Q>K No 1000Genomes
ENSVATH06585221 368 I>V No 1000Genomes
tmp_4_5840896_A_G 379 N>S No 1000Genomes
tmp_4_5840929_T_G 390 M>R No 1000Genomes
ENSVATH02757962 393 Q>R No 1000Genomes
ENSVATH00481955 402 Y>F No 1000Genomes
tmp_4_5840989_A_T 410 N>I No 1000Genomes
ENSVATH11355971 411 K>T No 1000Genomes
tmp_4_5840995_A_G 412 D>G No 1000Genomes
tmp_4_5841060_T_G 434 F>V No 1000Genomes
tmp_4_5841082_A_G 441 N>S No 1000Genomes
ENSVATH02757963 451 T>M No 1000Genomes
tmp_4_5841136_A_G 459 K>R No 1000Genomes
tmp_4_5841142_C_T 461 S>F No 1000Genomes
tmp_4_5841328_C_T 497 P>S No 1000Genomes
ENSVATH08315399 517 S>G No 1000Genomes
tmp_4_5841390_C_A 517 S>R No 1000Genomes
tmp_4_5841397_G_C 520 V>L No 1000Genomes
ENSVATH11355972 522 A>T No 1000Genomes
tmp_4_5841422_C_A 528 A>E No 1000Genomes
ENSVATH02757968 533 K>R No 1000Genomes
tmp_4_5841536_A_C 538 E>D No 1000Genomes
tmp_4_5841546_G_C 542 V>L No 1000Genomes
ENSVATH06585228 557 D>N No 1000Genomes
ENSVATH06585229 561 D>N No 1000Genomes
tmp_4_5841618_G_A 566 E>K No 1000Genomes
ENSVATH02757971 569 V>I No 1000Genomes
ENSVATH06585230 573 T>I No 1000Genomes
tmp_4_5841952_G_A 601 G>R No 1000Genomes
ENSVATH06585237 603 E>K No 1000Genomes
ENSVATH02757977 606 P>S No 1000Genomes
ENSVATH00481961 627 E>D No 1000Genomes
ENSVATH02757978 630 V>A No 1000Genomes
ENSVATH11356018 631 S>Y No 1000Genomes
tmp_4_5842047_T_G 632 H>Q No 1000Genomes
tmp_4_5842075_A_G 642 I>V No 1000Genomes
tmp_4_5842090_G_A 647 D>N No 1000Genomes
ENSVATH11356019 652 T>S No 1000Genomes
ENSVATH06585238 655 M>R No 1000Genomes
ENSVATH11356020 656 L>F No 1000Genomes
ENSVATH02757979 657 I>T No 1000Genomes

No associated diseases with Q9M0R2

3 regional properties for Q9M0R2

Type Name Position InterPro Accession
domain CRAL-TRIO lipid binding domain 377 - 552 IPR001251
domain GOLD domain 556 - 662 IPR009038
domain CRAL/TRIO, N-terminal domain 308 - 363 IPR011074

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Peripheral membrane protein
  • Cytoplasm
  • Mainly membrane-associated
  • Also cytoplasmic (By similarity)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

1 GO annotations of molecular function

Name Definition
lipid binding Binding to a lipid.

4 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
cellular response to auxin stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
protein localization involved in auxin polar transport Any protein localization that is involved in auxin polar transport.

26 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5SYC1 CLVS2 Clavesin-2 Homo sapiens (Human) PR
Q9BTX7 TTPAL Alpha-tocopherol transfer protein-like Homo sapiens (Human) PR
Q92503 SEC14L1 SEC14-like protein 1 Homo sapiens (Human) PR
Q8IUQ0 CLVS1 Clavesin-1 Homo sapiens (Human) PR
Q9UDX3 SEC14L4 SEC14-like protein 4 Homo sapiens (Human) PR
B5MCN3 SEC14L6 Putative SEC14-like protein 6 Homo sapiens (Human) PR
Q8BG92 Clvs2 Clavesin-2 Mus musculus (Mouse) PR
Q9D4C9 Clvs1 Clavesin-1 Mus musculus (Mouse) PR
Q9D3D0 Ttpal Alpha-tocopherol transfer protein-like Mus musculus (Mouse) PR
Q8R0F9 Sec14l4 SEC14-like protein 4 Mus musculus (Mouse) PR
A6JFQ6 Clvs1 Clavesin-1 Rattus norvegicus (Rat) PR
A6JUQ6 Clvs2 Clavesin-2 Rattus norvegicus (Rat) PR
Q09270 C34C12.6 CRAL-TRIO domain-containing protein C34C12.6 Caenorhabditis elegans PR
Q8GXC6 SFH5 Phosphatidylinositol/phosphatidylcholine transfer protein SFH5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SIW3 SFH7 Phosphatidylinositol/phosphatidylcholine transfer protein SFH7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SI13 SFH10 Phosphatidylinositol/phosphatidylcholine transfer protein SFH10 Arabidopsis thaliana (Mouse-ear cress) PR
F4IHJ0 SFH8 Phosphatidylinositol/phosphatidylcholine transfer protein SFH8 Arabidopsis thaliana (Mouse-ear cress) PR
Q93ZE9 SFH3 Phosphatidylinositol/phosphatidylcholine transfer protein SFH3 Arabidopsis thaliana (Mouse-ear cress) PR
F4J7S8 SFH9 Phosphatidylinositol/phosphatidylcholine transfer protein SFH9 Arabidopsis thaliana (Mouse-ear cress) PR
Q94A34 SFH12 Phosphatidylinositol/phosphatidylcholine transfer protein SFH12 Arabidopsis thaliana (Mouse-ear cress) PR
F4JVA6 SFH6 Phosphatidylinositol/phosphatidylcholine transfer protein SFH6 Arabidopsis thaliana (Mouse-ear cress) PR
Q56WK6 PATL1 Patellin-1 Arabidopsis thaliana (Mouse-ear cress) PR
Q56Z59 PATL3 Patellin-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q56ZI2 PATL2 Patellin-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q94C59 PATL4 Patellin-4 Arabidopsis thaliana (Mouse-ear cress) PR
Q5SPP0 clvs2 Clavesin-2 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MSQDSATTTP PPPLTSDVSM PSGEEDEPKH VTSEEEAPVT SETNLKLPLM PELEESNHTA
70 80 90 100 110 120
EVVSEKVTPE TMTLESEGLN HAAEDSEQTH EVTPETETAK LEVLNHTAED SEQTHEVTPE
130 140 150 160 170 180
KETVKSEFLN HVAEDSEQTH EVTPETETVK SEVLNHAAED SEQPRGVTPT PETETSEADT
190 200 210 220 230 240
SLLVTSETEE PNHAAEDYSE TEPSQKLMLE QRRKYMEVED WTEPELPDEA VLEAAASVPE
250 260 270 280 290 300
PKQPEPQTPP PPPSTTTSTV ASRSLAEMMN REEAEVEEKQ KIQIPRSLGS FKEETNKISD
310 320 330 340 350 360
LSETELNALQ ELRHLLQVSQ DSSKTSIWGV PLLKDDRTDV VLLKFLRARD FKPQEAYSML
370 380 390 400 410 420
NKTLQWRIDF NIEELLDENL GDDLDKVVFM QGQDKENHPV CYNVYGEFQN KDLYQKTFSD
430 440 450 460 470 480
EEKRERFLRW RIQFLEKSIR NLDFVAGGVS TICQVNDLKN SPGPGKTELR LATKQALHLL
490 500 510 520 530 540
QDNYPEFVSK QIFINVPWWY LAFYRIISPF MSQRSKSKLV FAGPSRSAET LLKYISPEHV
550 560 570 580 590 600
PVQYGGLSVD NCECNSDFTH DDIATEITVK PTTKQTVEII VYEKCTIVWE IRVVGWEVSY
610 620 630 640 650 660
GAEFVPENKE GYTVIIQKPR KMTAKNELVV SHSFKVGEVG RILLTVDNPT STKKMLIYRF
KVKPLACE