Q56ZI2
PR
Gene name |
PATL2 (At1g22530, F12K8.13) |
Protein name |
Patellin-2 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G22530 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q56ZI2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q56ZI2-F1 | Predicted | AlphaFoldDB |
58 variants for Q56ZI2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_1_7958292_G_A | 12 | S>F | No | 1000Genomes | |
| tmp_1_7958257_C_G | 24 | V>L | No | 1000Genomes | |
| tmp_1_7958238_G_A | 30 | P>L | No | 1000Genomes | |
| tmp_1_7958158_C_T | 57 | E>K | No | 1000Genomes | |
| ENSVATH13945651 | 59 | E>A | No | 1000Genomes | |
| tmp_1_7958146_T_C | 61 | T>A | No | 1000Genomes | |
| ENSVATH04623733 | 62 | A>P | No | 1000Genomes | |
| tmp_1_7958124_A_G | 68 | V>A | No | 1000Genomes | |
| ENSVATH11799378 | 74 | I>M | No | 1000Genomes | |
| tmp_1_7958077_C_T | 84 | G>S | No | 1000Genomes | |
| tmp_1_7958074_A_T | 85 | Y>N | No | 1000Genomes | |
| ENSVATH01088721 | 93 | A>P | No | 1000Genomes | |
| tmp_1_7958040_T_A | 96 | N>I | No | 1000Genomes | |
| tmp_1_7958037_G_A | 97 | A>V | No | 1000Genomes | |
| tmp_1_7957988_T_G | 113 | E>D | No | 1000Genomes | |
| tmp_1_7957962_G_A | 122 | A>V | No | 1000Genomes | |
| tmp_1_7957930_T_C | 133 | K>E | No | 1000Genomes | |
| ENSVATH11799377 | 151 | L>P | No | 1000Genomes | |
| ENSVATH11799184 | 153 | A>P | No | 1000Genomes | |
| tmp_1_7957860_T_C | 156 | K>R | No | 1000Genomes | |
| ENSVATH04623732 | 161 | S>Y | No | 1000Genomes | |
| ENSVATH01088717 | 162 | A>P | No | 1000Genomes | |
| tmp_1_7957810_C_T | 173 | E>K | No | 1000Genomes | |
| ENSVATH01088716 | 174 | I>V | No | 1000Genomes | |
| ENSVATH11799182 | 179 | A>P | No | 1000Genomes | |
| ENSVATH04623731 | 182 | V>I | No | 1000Genomes | |
| ENSVATH04623730 | 199 | T>N | No | 1000Genomes | |
| tmp_1_7957722_G_A | 202 | A>V | No | 1000Genomes | |
| tmp_1_7957683_A_G | 215 | L>S | No | 1000Genomes | |
| tmp_1_7957620_G_T | 236 | T>K | No | 1000Genomes | |
| ENSVATH11799180 | 238 | A>V | No | 1000Genomes | |
| ENSVATH01088713 | 239 | A>S | No | 1000Genomes | |
| ENSVATH11799179 | 240 | P>L | No | 1000Genomes | |
| ENSVATH13945647 | 241 | V>D | No | 1000Genomes | |
| tmp_1_7957603_T_C | 242 | T>A | No | 1000Genomes | |
| tmp_1_7957602_G_A | 242 | T>I | No | 1000Genomes | |
| ENSVATH01088712 | 255 | T>S | No | 1000Genomes | |
| ENSVATH00037732 | 267 | G>V | No | 1000Genomes | |
| ENSVATH13945645 | 302 | K>T | No | 1000Genomes | |
| ENSVATH04623727 | 308 | A>T | No | 1000Genomes | |
| tmp_1_7957402_C_G | 309 | V>L | No | 1000Genomes | |
| tmp_1_7957371_T_G | 319 | D>A | No | 1000Genomes | |
| ENSVATH11799177 | 340 | P>T | No | 1000Genomes | |
| tmp_1_7957291_C_T | 346 | V>I | No | 1000Genomes | |
| ENSVATH13945624 | 400 | D>E | No | 1000Genomes | |
| tmp_1_7957101_C_T | 409 | S>N | No | 1000Genomes | |
| tmp_1_7957013_C_G | 438 | K>N | No | 1000Genomes | |
| ENSVATH04623724 | 470 | E>K | No | 1000Genomes | |
| tmp_1_7956461_C_T | 566 | V>I | No | 1000Genomes | |
| ENSVATH04623719 | 582 | G>E | No | 1000Genomes | |
| tmp_1_7956379_T_A | 593 | K>I | No | 1000Genomes | |
| ENSVATH11799082 | 595 | T>A | No | 1000Genomes | |
| tmp_1_7956362_G_A | 599 | P>S | No | 1000Genomes | |
| tmp_1_7955912_T_C | 638 | N>S | No | 1000Genomes | |
| tmp_1_7955880_T_A | 649 | I>L | No | 1000Genomes | |
| tmp_1_7955862_C_T | 655 | A>T | No | 1000Genomes | |
| tmp_1_7955853_C_G | 658 | A>P | No | 1000Genomes | |
| tmp_1_7955783_G_C | 681 | T>S | No | 1000Genomes |
No associated diseases with Q56ZI2
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| lipid binding | Binding to a lipid. |
| protease binding | Binding to a protease or a peptidase. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| cellular response to auxin stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus. |
| protein localization involved in auxin polar transport | Any protein localization that is involved in auxin polar transport. |
26 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q5SYC1 | CLVS2 | Clavesin-2 | Homo sapiens (Human) | PR |
| Q9BTX7 | TTPAL | Alpha-tocopherol transfer protein-like | Homo sapiens (Human) | PR |
| Q92503 | SEC14L1 | SEC14-like protein 1 | Homo sapiens (Human) | PR |
| Q8IUQ0 | CLVS1 | Clavesin-1 | Homo sapiens (Human) | PR |
| Q9UDX3 | SEC14L4 | SEC14-like protein 4 | Homo sapiens (Human) | PR |
| B5MCN3 | SEC14L6 | Putative SEC14-like protein 6 | Homo sapiens (Human) | PR |
| Q8BG92 | Clvs2 | Clavesin-2 | Mus musculus (Mouse) | PR |
| Q9D4C9 | Clvs1 | Clavesin-1 | Mus musculus (Mouse) | PR |
| Q9D3D0 | Ttpal | Alpha-tocopherol transfer protein-like | Mus musculus (Mouse) | PR |
| Q8R0F9 | Sec14l4 | SEC14-like protein 4 | Mus musculus (Mouse) | PR |
| A6JFQ6 | Clvs1 | Clavesin-1 | Rattus norvegicus (Rat) | PR |
| A6JUQ6 | Clvs2 | Clavesin-2 | Rattus norvegicus (Rat) | PR |
| Q09270 | C34C12.6 | CRAL-TRIO domain-containing protein C34C12.6 | Caenorhabditis elegans | PR |
| Q8GXC6 | SFH5 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SIW3 | SFH7 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SI13 | SFH10 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH10 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4IHJ0 | SFH8 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH8 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q93ZE9 | SFH3 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4J7S8 | SFH9 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94A34 | SFH12 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH12 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4JVA6 | SFH6 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q56WK6 | PATL1 | Patellin-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q56Z59 | PATL3 | Patellin-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94C59 | PATL4 | Patellin-4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M0R2 | PATL5 | Patellin-5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q5SPP0 | clvs2 | Clavesin-2 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAQEEIQKPT | ASVPVVKEET | PAPVKEVEVP | VTTEKAVAAP | APEATEEKVV | SEVAVPETEV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TAVKEEEVAT | GKEILQSESF | KEEGYLASEL | QEAEKNALAE | LKELVREALN | KREFTAPPPP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PAPVKEEKVE | EKKTEETEEK | KEEVKTEEKS | LEAETKEEEK | SAAPATVETK | KEEILAAPAP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IVAETKKEET | PVAPAPVETK | PAAPVVAETK | KEEILPAAPV | TTETKVEEKV | VPVETTPAAP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VTTETKEEEK | AAPVTTETKE | EEKAAPGETK | KEEKATASTQ | VKRASKFIKD | IFVSVTTSEK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KKEEEKPAVV | TIEKAFAADQ | EEETKTVEAV | EESIVSITLP | ETAAYVEPEE | VSIWGIPLLE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DERSDVILLK | FLRARDFKVK | EAFTMLKNTV | QWRKENKIDD | LVSEDLEGSE | FEKLVFTHGV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DKQGHVVIYS | SYGEFQNKEI | FSDKEKLSKF | LKWRIQFQEK | CVRSLDFSPE | AKSSFVFVSD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| FRNAPGLGQR | ALWQFIKRAV | KQFEDNYPEF | VAKELFINVP | WWYIPYYKTF | GSIITSPRTR |
| 550 | 560 | 570 | 580 | 590 | 600 |
| SKMVLSGPSK | SAETIFKYVA | PEVVPVKYGG | LSKDSPFTVE | DGVTEAVVKS | TSKYTIDLPA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TEGSTLSWEL | RVLGADVSYG | AQFEPSNEAS | YTVIVSKNRK | VGLTDEPVIT | DSFKASEAGK |
| 670 | 680 | ||||
| VVITIDNQTF | KKKKVLYRSK | TQA |