F4JVA6
PR
Gene name |
SFH6 (At4g39170, T22F8.70) |
Protein name |
Phosphatidylinositol/phosphatidylcholine transfer protein SFH6 |
Names |
Protein SEC FOURTEEN HOMOLOGS 6, AtSFH6 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G39170 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for F4JVA6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-F4JVA6-F1 | Predicted | AlphaFoldDB |
41 variants for F4JVA6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_4_18240891_C_T | 2 | S>L | No | 1000Genomes | |
| tmp_4_18241166_G_A | 15 | G>E | No | 1000Genomes | |
| tmp_4_18241165_G_A | 15 | G>R | No | 1000Genomes | |
| tmp_4_18241331_G_C | 70 | S>T | No | 1000Genomes | |
| ENSVATH12496470 | 102 | K>N | No | 1000Genomes | |
| tmp_4_18241444_A_G | 108 | M>V | No | 1000Genomes | |
| ENSVATH14359919 | 141 | T>A | No | 1000Genomes | |
| ENSVATH06852052 | 147 | Q>R | No | 1000Genomes | |
| tmp_4_18241743_G_A | 207 | M>I | No | 1000Genomes | |
| ENSVATH02978900 | 207 | M>L | No | 1000Genomes | |
| tmp_4_18241768_G_A | 216 | A>T | No | 1000Genomes | |
| ENSVATH06852059 | 321 | T>I | No | 1000Genomes | |
| tmp_4_18242295_G_T | 323 | A>S | No | 1000Genomes | |
| ENSVATH12496507 | 325 | Q>R | No | 1000Genomes | |
| ENSVATH02978901 | 330 | L>V | No | 1000Genomes | |
| ENSVATH12496508 | 338 | N>I | No | 1000Genomes | |
| ENSVATH12496509 | 347 | H>Q | No | 1000Genomes | |
| tmp_4_18242455_G_A | 352 | R>H | No | 1000Genomes | |
| tmp_4_18242454_C_A | 352 | R>S | No | 1000Genomes | |
| tmp_4_18242553_G_A | 385 | A>T | No | 1000Genomes | |
| ENSVATH00559380 | 395 | V>I | No | 1000Genomes | |
| tmp_4_18242587_T_C | 396 | V>A | No | 1000Genomes | |
| tmp_4_18242602_T_A | 401 | V>E | No | 1000Genomes | |
| tmp_4_18242727_A_C | 417 | K>Q | No | 1000Genomes | |
| ENSVATH02978903 | 425 | F>L | No | 1000Genomes | |
| ENSVATH12496514 | 426 | A>V | No | 1000Genomes | |
| ENSVATH12496526 | 427 | G>A | No | 1000Genomes | |
| tmp_4_18242805_G_A | 443 | V>I | No | 1000Genomes | |
| tmp_4_18242844_C_T | 456 | R>W | No | 1000Genomes | |
| tmp_4_18242953_G_A | 464 | M>I | No | 1000Genomes | |
| ENSVATH02978904 | 464 | M>L | No | 1000Genomes | |
| tmp_4_18243029_A_T | 490 | I>F | No | 1000Genomes | |
| tmp_4_18243044_C_T | 495 | R>C | No | 1000Genomes | |
| ENSVATH12496528 | 499 | N>K | No | 1000Genomes | |
| ENSVATH00559381 | 517 | G>R | No | 1000Genomes | |
| ENSVATH14359923 | 546 | S>T | No | 1000Genomes | |
| ENSVATH02978906 | 602 | H>L | No | 1000Genomes | |
| tmp_4_18243461_C_T | 603 | Q>* | No | 1000Genomes | |
| tmp_4_18243586_A_C | 604 | K>Q | No | 1000Genomes | |
| tmp_4_18243594_T_A | 606 | N>K | No | 1000Genomes | |
| ENSVATH06852068 | 608 | R>W | No | 1000Genomes |
No associated diseases with F4JVA6
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
27 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9UDX3 | SEC14L4 | SEC14-like protein 4 | Homo sapiens (Human) | PR |
| Q5SYC1 | CLVS2 | Clavesin-2 | Homo sapiens (Human) | PR |
| Q9BTX7 | TTPAL | Alpha-tocopherol transfer protein-like | Homo sapiens (Human) | PR |
| Q92503 | SEC14L1 | SEC14-like protein 1 | Homo sapiens (Human) | PR |
| B5MCN3 | SEC14L6 | Putative SEC14-like protein 6 | Homo sapiens (Human) | PR |
| Q8IUQ0 | CLVS1 | Clavesin-1 | Homo sapiens (Human) | PR |
| Q8BG92 | Clvs2 | Clavesin-2 | Mus musculus (Mouse) | PR |
| Q9D4C9 | Clvs1 | Clavesin-1 | Mus musculus (Mouse) | PR |
| Q9D3D0 | Ttpal | Alpha-tocopherol transfer protein-like | Mus musculus (Mouse) | PR |
| Q8R0F9 | Sec14l4 | SEC14-like protein 4 | Mus musculus (Mouse) | PR |
| A6JFQ6 | Clvs1 | Clavesin-1 | Rattus norvegicus (Rat) | PR |
| A6JUQ6 | Clvs2 | Clavesin-2 | Rattus norvegicus (Rat) | PR |
| Q09270 | C34C12.6 | CRAL-TRIO domain-containing protein C34C12.6 | Caenorhabditis elegans | PR |
| Q56ZI2 | PATL2 | Patellin-2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94C59 | PATL4 | Patellin-4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q56WK6 | PATL1 | Patellin-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q56Z59 | PATL3 | Patellin-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M0R2 | PATL5 | Patellin-5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4IHJ0 | SFH8 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH8 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4J7S8 | SFH9 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GXC6 | SFH5 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94A34 | SFH12 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH12 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SI13 | SFH10 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH10 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SIW3 | SFH7 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q93ZE9 | SFH3 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q501H5 | SFH13 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH13 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q5SPP0 | clvs2 | Clavesin-2 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSGPVDRFAI | PCFEGILSSD | EKKERKSDFE | NSEDERRTRI | GSLKKKAINA | STKFKHSLKK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KRRKSDVRVS | SVSIEDVRDV | EELQAVDEFR | QALVMEELLP | HKHDDYHMML | RFLKARKFDI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EKAKHMWADM | IQWRKEFGTD | TIIQDFQFEE | IDEVLKYYPH | GYHSVDKEGR | PVYIERLGKV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DPNKLMQVTT | LDRYIRYHVK | EFERSFMLKF | PACTIAAKKY | IDSSTTILDV | QGVGLKNFTK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SARELITRLQ | KIDGDNYPET | LHQMFIINAG | PGFRLLWSTV | KSFLDPKTTS | KIHVLGCKYQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SKLLEIIDSS | ELPEFLGGAC | TCADQGGCML | SDKGPWKNPE | IVKMVLHGGA | HRAKQVVKVL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NSDGKVIAYA | KPSYPWIKGS | DTSTAESGSE | AEDIVVSPKA | VKSYSHLRLT | PVREEAKVGS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GETSFAGSFA | GYDEYVPMVD | KAVDATWKVK | PTAINRAPSK | GAHMPPNVPK | DHESFSARVL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VTFMAFVMAI | LTFFRTVSNR | VVTKQLPPPP | SQPQIEGSAA | AEEADLLNSV | LKKLTELEEK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IGALQSKPSE | MPYEKEELLN | AAVCRVDALE | AELIATKKAL | YEALMRQEEL | LAYIDRQEAA |
| 610 | |||||
| QHQKKNKRKQ | MFCF |