F4IHJ0
PR
Gene name |
SFH8 (At2g21520, F3K23.28) |
Protein name |
Phosphatidylinositol/phosphatidylcholine transfer protein SFH8 |
Names |
Protein SEC FOURTEEN HOMOLOGS 8, AtSFH8 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G21520 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for F4IHJ0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-F4IHJ0-F1 | Predicted | AlphaFoldDB |
35 variants for F4IHJ0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH14528351 | 3 | G>S | No | 1000Genomes | |
| ENSVATH05549070 | 12 | C>W | No | 1000Genomes | |
| tmp_2_9216292_G_C | 36 | R>T | No | 1000Genomes | |
| tmp_2_9216501_G_A | 106 | D>N | No | 1000Genomes | |
| ENSVATH05549073 | 122 | V>A | No | 1000Genomes | |
| ENSVATH05549074 | 134 | Q>R | No | 1000Genomes | |
| ENSVATH01858842 | 146 | Q>K | No | 1000Genomes | |
| ENSVATH05549076 | 158 | K>I | No | 1000Genomes | |
| tmp_2_9216836_A_T | 193 | M>L | No | 1000Genomes | |
| ENSVATH01858849 | 303 | S>I | No | 1000Genomes | |
| ENSVATH05549082 | 312 | N>H | No | 1000Genomes | |
| tmp_2_9217564_C_T | 321 | A>V | No | 1000Genomes | |
| tmp_2_9217628_A_T | 342 | E>D | No | 1000Genomes | |
| ENSVATH05549086 | 377 | T>K | No | 1000Genomes | |
| tmp_2_9217821_A_C | 377 | T>P | No | 1000Genomes | |
| tmp_2_9217969_G_A | 397 | G>S | No | 1000Genomes | |
| ENSVATH05549087 | 403 | K>T | No | 1000Genomes | |
| tmp_2_9218011_A_G | 411 | T>A | No | 1000Genomes | |
| ENSVATH05549090 | 428 | S>C | No | 1000Genomes | |
| tmp_2_9218226_G_T | 459 | R>I | No | 1000Genomes | |
| ENSVATH13315894 | 463 | M>L | No | 1000Genomes | |
| ENSVATH05549104 | 466 | T>A | No | 1000Genomes | |
| ENSVATH01858866 | 470 | D>V | No | 1000Genomes | |
| ENSVATH00241486 | 471 | H>P | No | 1000Genomes | |
| ENSVATH14528366 | 473 | G>S | No | 1000Genomes | |
| ENSVATH05549105 | 478 | V>F | No | 1000Genomes | |
| tmp_2_9218500_G_T | 483 | M>I | No | 1000Genomes | |
| tmp_2_9218501_G_A | 484 | A>T | No | 1000Genomes | |
| ENSVATH05549106 | 485 | F>I | No | 1000Genomes | |
| ENSVATH13315915 | 488 | A>T | No | 1000Genomes | |
| ENSVATH05549107 | 489 | V>L | No | 1000Genomes | |
| tmp_2_9218559_C_G | 503 | T>S | No | 1000Genomes | |
| tmp_2_9218603_C_A | 518 | L>I | No | 1000Genomes | |
| ENSVATH13315917 | 569 | P>S | No | 1000Genomes | |
| ENSVATH15083198 | 623 | K>M | No | 1000Genomes |
No associated diseases with F4IHJ0
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
27 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9UDX3 | SEC14L4 | SEC14-like protein 4 | Homo sapiens (Human) | PR |
| Q5SYC1 | CLVS2 | Clavesin-2 | Homo sapiens (Human) | PR |
| Q9BTX7 | TTPAL | Alpha-tocopherol transfer protein-like | Homo sapiens (Human) | PR |
| Q92503 | SEC14L1 | SEC14-like protein 1 | Homo sapiens (Human) | PR |
| B5MCN3 | SEC14L6 | Putative SEC14-like protein 6 | Homo sapiens (Human) | PR |
| Q8IUQ0 | CLVS1 | Clavesin-1 | Homo sapiens (Human) | PR |
| Q8R0F9 | Sec14l4 | SEC14-like protein 4 | Mus musculus (Mouse) | PR |
| Q8BG92 | Clvs2 | Clavesin-2 | Mus musculus (Mouse) | PR |
| Q9D4C9 | Clvs1 | Clavesin-1 | Mus musculus (Mouse) | PR |
| Q9D3D0 | Ttpal | Alpha-tocopherol transfer protein-like | Mus musculus (Mouse) | PR |
| A6JFQ6 | Clvs1 | Clavesin-1 | Rattus norvegicus (Rat) | PR |
| A6JUQ6 | Clvs2 | Clavesin-2 | Rattus norvegicus (Rat) | PR |
| Q09270 | C34C12.6 | CRAL-TRIO domain-containing protein C34C12.6 | Caenorhabditis elegans | PR |
| Q56ZI2 | PATL2 | Patellin-2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94C59 | PATL4 | Patellin-4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q56WK6 | PATL1 | Patellin-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q56Z59 | PATL3 | Patellin-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M0R2 | PATL5 | Patellin-5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4J7S8 | SFH9 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4JVA6 | SFH6 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GXC6 | SFH5 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94A34 | SFH12 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH12 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SI13 | SFH10 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH10 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SIW3 | SFH7 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q93ZE9 | SFH3 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q501H5 | SFH13 | Phosphatidylinositol/phosphatidylcholine transfer protein SFH13 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q5SPP0 | clvs2 | Clavesin-2 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSGPLDRFAR | PCFEGFLSSD | EKKERKSDFE | NSEDERRTRI | GSLKKKAINA | STKFKHSLKK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KSGRRKSDGR | VSSVSIEDVR | DVEELQAVDA | FRQSLLMDEL | LPDRHDDYHM | MLRFLKARKF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DVEKAKQMWA | DMIQWRKEFG | TDTIIQDFDF | EEINEVLKHY | PQCYHGVDKE | GRPIYIERLG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KVDPNRLMQV | TSMDRYVRYH | VKEFERSFMI | KFPSCTISAK | RHIDSSTTIL | DVQGVGLKNF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NKSARDLITR | LQKIDGDNYP | ETLHQMFIIN | AGPGFRLLWN | TVKSFLDPKT | SAKIHVLGYK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YLSKLLEVID | VNELPEFLGG | ACTCADQGGC | MLSDKGPWKN | PEIVKMVLHG | GAHRARQVVK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VLNSEGKVIA | YAKPSYTWIK | GSDTSTAESG | SDAEDIGSPK | AIKSFSHLRL | TPVREEAKIA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GETSLAGSFP | GYDEYVPMVD | KAVDATWKVK | PAIQRVASRG | ALMSPTVPKD | HEGIKARVLV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| MFMAFLMAVF | TFFRTVTKKL | PATTTSSPAE | TQGNAIELGS | NGEGVKEECR | PPSPVPDLTE |
| 550 | 560 | 570 | 580 | 590 | 600 |
| TDLLNCVTKK | LTELEGKIGT | LQSKPNEMPY | EKEELLNAAV | CRVDALEAEL | IATKKALYEA |
| 610 | 620 | 630 | |||
| LMRQEELLAY | IDRQEEAQFQ | KMKKKKKKHL | FCF |