Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8R0F9

Entry ID Method Resolution Chain Position Source
AF-Q8R0F9-F1 Predicted AlphaFoldDB

33 variants for Q8R0F9

Variant ID(s) Position Change Description Diseaes Association Provenance
rs13480838 18 R>S No EVA
rs3401854089 19 F>I No EVA
rs3401854120 20 R>L No EVA
rs3401777333 22 T>A No EVA
rs246540981 22 T>N No EVA
rs246540981 22 T>S No EVA
rs3400599028 25 D>E No EVA
rs3401945730 55 M>R No EVA
rs3389132997 56 L>H No EVA
rs3401794714 56 L>V No EVA
rs3402056356 57 R>P No EVA
rs3389142172 77 P>S No EVA
rs240063316 112 F>L No EVA
rs255496413 125 I>L No EVA
rs3389142109 135 C>Y No EVA
rs234950402 159 S>G No EVA
rs3389150306 160 L>P No EVA
rs258986184 191 I>V No EVA
rs222241512 192 I>V No EVA
rs3389140482 205 V>A No EVA
rs3389138057 234 P>H No EVA
rs3389138069 262 G>D No EVA
rs3389138307 268 Y>* No EVA
rs3389127007 274 E>D No EVA
rs3401445036 274 E>G No EVA
rs3401895821 274 E>K No EVA
rs3401158717 275 R>S No EVA
rs3401698721 275 R>W No EVA
rs3389138232 277 Q>R No EVA
rs3413006363 278 Y>* No EVA
rs3389150288 316 F>I No EVA
rs3389139329 393 K>M No EVA
rs241175964 400 V>M No EVA

No associated diseases with Q8R0F9

3 regional properties for Q8R0F9

Type Name Position InterPro Accession
domain CRAL-TRIO lipid binding domain 76 - 249 IPR001251
domain GOLD domain 275 - 383 IPR009038
domain CRAL/TRIO, N-terminal domain 34 - 59 IPR011074

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
lipid binding Binding to a lipid.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

27 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5SYC1 CLVS2 Clavesin-2 Homo sapiens (Human) PR
Q9BTX7 TTPAL Alpha-tocopherol transfer protein-like Homo sapiens (Human) PR
Q8IUQ0 CLVS1 Clavesin-1 Homo sapiens (Human) PR
Q92503 SEC14L1 SEC14-like protein 1 Homo sapiens (Human) PR
B5MCN3 SEC14L6 Putative SEC14-like protein 6 Homo sapiens (Human) PR
Q9UDX3 SEC14L4 SEC14-like protein 4 Homo sapiens (Human) PR
Q8BG92 Clvs2 Clavesin-2 Mus musculus (Mouse) PR
Q9D4C9 Clvs1 Clavesin-1 Mus musculus (Mouse) PR
Q9D3D0 Ttpal Alpha-tocopherol transfer protein-like Mus musculus (Mouse) PR
A6JFQ6 Clvs1 Clavesin-1 Rattus norvegicus (Rat) PR
A6JUQ6 Clvs2 Clavesin-2 Rattus norvegicus (Rat) PR
Q09270 C34C12.6 CRAL-TRIO domain-containing protein C34C12.6 Caenorhabditis elegans PR
Q8GXC6 SFH5 Phosphatidylinositol/phosphatidylcholine transfer protein SFH5 Arabidopsis thaliana (Mouse-ear cress) PR
F4IHJ0 SFH8 Phosphatidylinositol/phosphatidylcholine transfer protein SFH8 Arabidopsis thaliana (Mouse-ear cress) PR
F4J7S8 SFH9 Phosphatidylinositol/phosphatidylcholine transfer protein SFH9 Arabidopsis thaliana (Mouse-ear cress) PR
Q56WK6 PATL1 Patellin-1 Arabidopsis thaliana (Mouse-ear cress) PR
Q56Z59 PATL3 Patellin-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q56ZI2 PATL2 Patellin-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q94A34 SFH12 Phosphatidylinositol/phosphatidylcholine transfer protein SFH12 Arabidopsis thaliana (Mouse-ear cress) PR
Q94C59 PATL4 Patellin-4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M0R2 PATL5 Patellin-5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SI13 SFH10 Phosphatidylinositol/phosphatidylcholine transfer protein SFH10 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SIW3 SFH7 Phosphatidylinositol/phosphatidylcholine transfer protein SFH7 Arabidopsis thaliana (Mouse-ear cress) PR
F4JVA6 SFH6 Phosphatidylinositol/phosphatidylcholine transfer protein SFH6 Arabidopsis thaliana (Mouse-ear cress) PR
Q93ZE9 SFH3 Phosphatidylinositol/phosphatidylcholine transfer protein SFH3 Arabidopsis thaliana (Mouse-ear cress) PR
Q501H5 SFH13 Phosphatidylinositol/phosphatidylcholine transfer protein SFH13 Arabidopsis thaliana (Mouse-ear cress) PR
Q5SPP0 clvs2 Clavesin-2 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MRGQVGDLSP QQQEALARFR ETLQDLLPTL PKADDYFLLR WLRARNFDLK KSEDMLRKHV
70 80 90 100 110 120
EFRNQQNLDQ ILTWQAPEVI QLYDSGGLSG YDYEGCPVWF DIIGTMDPKG LFMSASKQDM
130 140 150 160 170 180
IRKRIKVCEM LLHECELQSQ KLGRKIERMV MVFDMEGLSL RHLWKPAVEV YQQFFAILEA
190 200 210 220 230 240
NYPETVKNLI IIRAPKLFPV AFNLVKSFMG EETQKKIVIL GGNWKQELVK FVSPDQLPVE
250 260 270 280 290 300
FGGTMTDPDG NPKCLTKINY GGEVPKRYYL SNQERPQYEH SVVVGRGSSH QVENEILFPG
310 320 330 340 350 360
CVLRWQFASD GGDIGFGVFL KTRMGERQKA GEMVEVLPSQ RYNAHMVPED GSLNCLKAGV
370 380 390 400
YVLRFDNTYS LLHTKKVGYT AEVLLPDKAC EEKLQGLGSV SPP