P31641
PR
Gene name |
SLC6A6 |
Protein name |
Sodium- and chloride-dependent taurine transporter |
Names |
Solute carrier family 6 member 6 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:6533 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P31641
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P31641-F1 | Predicted | AlphaFoldDB |
339 variants for P31641
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
RCV001089880 RCV001449581 rs754954058 VAR_083336 |
78 | A>E | Hypertaurinuric cardiomyopathy Retinal degeneration HTRDC; severely decreased taurine transport activity in patient cells; does not affect cell membrane localization [ClinVar, UniProt] | Yes |
ClinVar dbSNP UniProt |
|
RCV001449580 VAR_083337 RCV001089879 rs1700769766 |
399 | G>V | Hypertaurinuric cardiomyopathy Retinal degeneration HTRDC; decreased taurine transport activity; does not affect protein abundance; does not affect cell membrane localization [ClinVar, UniProt] | Yes |
ClinVar dbSNP UniProt |
|
CA351543447 rs1320425471 |
2 | A>T | No |
ClinGen gnomAD |
|
|
rs767752911 CA2268076 |
8 | Q>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA69794783 rs938241915 |
8 | Q>R | No |
ClinGen Ensembl |
|
|
rs756211186 CA2268078 |
9 | C>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs777774845 CA2268079 |
9 | C>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 12 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs894127539 CA351543557 |
17 | I>L | No |
ClinGen TOPMed |
|
|
CA69794845 VAR_011767 rs1042350 |
17 | I>M | No |
ClinGen UniProt Ensembl dbSNP |
|
|
rs894127539 CA69794843 |
17 | I>V | No |
ClinGen TOPMed |
|
|
rs1042351 CA69794853 VAR_011768 |
18 | L>V | No |
ClinGen UniProt dbSNP gnomAD |
|
|
rs1559298038 CA351543605 |
21 | S>A | No |
ClinGen Ensembl |
|
|
rs1014442973 CA69794856 |
21 | S>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA2268081 rs56135743 |
23 | G>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA351543658 rs1269202473 |
25 | S>T | No |
ClinGen gnomAD |
|
|
rs1435119922 CA351543698 |
28 | T>M | No |
ClinGen TOPMed gnomAD |
|
|
rs375588796 CA351543708 |
29 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs375588796 CA2268084 |
29 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs746221976 CA2268083 |
29 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs780928107 CA2268085 |
30 | P>H | No |
ClinGen ExAC gnomAD |
|
|
CA2268086 rs747752099 |
31 | E>* | No |
ClinGen ExAC gnomAD |
|
|
CA351543728 rs747752099 |
31 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA2268088 rs772779498 |
33 | E>K | No |
ClinGen ExAC TOPMed |
|
|
CA69794882 rs147424926 |
36 | G>R | No |
ClinGen ESP TOPMed |
|
|
rs763048151 CA2268089 |
37 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs770884063 CA2268090 |
39 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs571621473 CA2268091 |
39 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 43 | K>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs369985102 CA2268094 |
48 | I>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs369985102 CA69794922 |
48 | I>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
RCV000998004 CA351543978 rs1364177670 |
49 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ClinVar NCI-TCGA TOPMed dbSNP |
|
rs1318976460 CA351543994 |
51 | V>L | No |
ClinGen TOPMed |
|
|
rs576174099 CA2268100 |
57 | G>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1397163579 CA351544041 |
59 | V>M | No |
ClinGen TOPMed |
|
|
rs373450965 CA2268105 |
64 | V>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA351544090 rs1219059633 |
66 | R>C | No |
ClinGen gnomAD |
|
|
CA351544092 rs1195960775 |
66 | R>H | No |
ClinGen TOPMed |
|
|
CA2268106 rs777479971 |
68 | P>R | No |
ClinGen ExAC gnomAD |
|
|
rs1188703308 CA351544108 |
69 | Y>H | No |
ClinGen gnomAD |
|
|
rs1239740889 CA351544117 |
70 | L>F | No |
ClinGen gnomAD |
|
|
CA351544141 rs1420517511 |
73 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
CA351544156 rs1471788439 |
75 | G>D | No |
ClinGen gnomAD |
|
|
rs1288395468 CA351544228 |
77 | G>D | No |
ClinGen TOPMed |
|
|
rs754954058 CA2268189 |
78 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752635304 CA2268191 |
81 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1221379240 CA351544260 |
82 | P>L | No |
ClinGen TOPMed |
|
|
TCGA novel rs1389920231 CA351544271 |
84 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen TOPMed gnomAD |
|
CA69797231 rs187304824 |
87 | L>P | No |
ClinGen 1000Genomes gnomAD |
|
|
CA351544294 rs1398818150 |
87 | L>V | No |
ClinGen TOPMed |
|
|
rs755880393 CA2268192 |
88 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs1340798819 CA351544303 |
88 | F>L | No |
ClinGen TOPMed |
|
|
CA351544318 rs1432704813 |
91 | G>S | No |
ClinGen TOPMed |
|
|
rs1305679234 CA351544335 |
94 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
rs1363070760 CA351544356 |
96 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
CA2268195 rs771266868 |
99 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs1448014656 CA351544379 |
100 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
rs779185771 CA2268196 |
101 | I>V | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 102 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1227969356 CA351544403 |
103 | Q>H | No |
ClinGen gnomAD |
|
|
rs1368341643 CA351544462 |
112 | C>S | No |
ClinGen gnomAD |
|
|
CA2268198 rs772239459 |
114 | E>G | No |
ClinGen ExAC |
|
|
CA2268197 rs368267241 |
114 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA69797306 rs140925115 |
115 | K>N | No |
ClinGen ESP gnomAD |
|
|
CA2268199 rs775885353 |
118 | P>R | No |
ClinGen ExAC gnomAD |
|
|
rs1034942334 CA69797352 |
121 | S>A | No |
ClinGen Ensembl |
|
|
CA2268219 rs776908877 |
123 | I>N | No |
ClinGen ExAC gnomAD |
|
|
rs754658920 CA69798898 |
123 | I>V | No |
ClinGen Ensembl |
|
|
CA351545049 rs1340576249 |
124 | G>S | No |
ClinGen gnomAD |
|
|
rs974566918 CA69798935 |
125 | Y>F | No |
ClinGen TOPMed |
|
|
CA2268222 rs774010319 |
127 | S>T | No |
ClinGen ExAC gnomAD |
|
|
rs62233560 CA2268224 |
128 | V>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1400077213 CA351545088 |
130 | I>T | No |
ClinGen TOPMed |
|
|
CA351545085 rs1291678747 |
130 | I>V | No |
ClinGen gnomAD |
|
|
CA351545091 rs1323802034 |
131 | V>L | No |
ClinGen gnomAD |
|
|
rs1213893387 CA351545101 |
132 | S>C | No |
ClinGen gnomAD |
|
|
CA351545149 rs777815176 |
139 | I>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2268226 rs760581480 |
139 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs753788057 CA2268228 |
140 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765067708 CA2268230 |
141 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs1398641041 CA351545170 |
143 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA69799001 rs993279878 |
144 | W>* | No |
ClinGen TOPMed |
|
|
rs1157648327 CA351545208 |
149 | L>M | No |
ClinGen TOPMed gnomAD |
|
|
CA351545209 rs1157648327 |
149 | L>V | No |
ClinGen TOPMed gnomAD |
|
|
CA2268231 rs750677480 |
150 | F>V | No |
ClinGen ExAC gnomAD |
|
|
rs1421013671 CA351545224 |
151 | Q>R | No |
ClinGen gnomAD |
|
|
rs746949208 CA2268233 |
157 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA351545285 rs1370867471 |
160 | A>T | No |
ClinGen gnomAD |
|
|
rs781685032 CA2268236 |
168 | T>I | No |
ClinGen ExAC |
|
|
CA351545356 rs1286880466 |
169 | P>H | No |
ClinGen TOPMed |
|
|
rs1005174469 CA69799057 |
170 | H>Y | No |
ClinGen gnomAD |
|
|
CA351545379 rs1465977145 |
172 | M>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs948922400 CA69799062 |
172 | M>R | No |
ClinGen TOPMed |
|
|
rs1285603719 CA351545375 |
172 | M>V | No |
ClinGen gnomAD |
|
|
rs767489625 CA2268238 |
177 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2268239 rs554039615 |
177 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA351545450 rs1211410002 |
182 | V>I | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 185 | T>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA351545484 rs1335864670 |
186 | I>M | No |
ClinGen TOPMed gnomAD |
|
|
CA351545483 rs1468956193 |
186 | I>S | No |
ClinGen gnomAD |
|
|
rs1239625158 CA351545480 |
186 | I>V | No |
ClinGen gnomAD |
|
|
rs369822270 CA69799075 |
187 | S>C | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs745583072 CA2268240 |
187 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA69799107 rs774906046 |
188 | S>C | No |
ClinGen ExAC gnomAD |
|
|
rs774906046 CA2268242 |
188 | S>Y | No |
ClinGen ExAC gnomAD |
|
|
CA2268244 rs768003614 |
189 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs768003614 CA351545495 |
189 | T>P | No |
ClinGen ExAC gnomAD |
|
|
CA351545514 rs1415021405 |
191 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
CA351545521 rs1320201655 |
192 | T>I | No |
ClinGen TOPMed |
|
|
rs761777238 CA2268246 |
193 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA351545549 rs1207552494 |
197 | E>A | No |
ClinGen gnomAD |
|
|
CA351545548 rs1378008067 |
197 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA351545546 rs1378008067 |
197 | E>Q | No |
ClinGen gnomAD |
|
| TCGA novel | 200 | E>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA351545597 rs1208382537 |
201 | R>C | No |
ClinGen gnomAD |
|
|
CA2268272 rs138163519 |
201 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1200454118 CA351545608 CA351545607 |
202 | N>K | No |
ClinGen TOPMed gnomAD |
|
|
CA351545604 rs1451753524 |
202 | N>S | No |
ClinGen gnomAD |
|
|
CA2268273 rs767645569 |
203 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA2268276 rs778286920 |
205 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs765906100 CA69757218 |
205 | S>R | No |
ClinGen TOPMed |
|
| TCGA novel | 206 | L>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA2268280 rs746743487 |
208 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs747629906 CA2268283 |
211 | D>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1399975164 CA351545667 |
212 | H>R | No |
ClinGen gnomAD |
|
|
CA351545665 rs1338494803 |
212 | H>Y | No |
ClinGen gnomAD |
|
|
CA2268285 rs377494450 |
215 | S>C | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1559305145 CA351545714 |
219 | D>G | No |
ClinGen Ensembl |
|
| TCGA novel | 219 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA2268288 rs774009626 |
221 | A>G | No |
ClinGen ExAC gnomAD |
|
|
CA2268287 rs770761525 |
221 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA2268289 rs759805633 |
226 | L>V | No |
ClinGen ExAC gnomAD |
|
|
CA69757383 rs200442035 |
230 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
rs201094151 CA2268292 |
239 | V>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA2268293 rs764103908 |
240 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA2268294 rs754374495 |
240 | R>K | No |
ClinGen ExAC gnomAD |
|
|
CA2268295 rs757701813 |
241 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA351545895 rs1307447325 |
245 | V>I | No |
ClinGen gnomAD |
|
|
rs1375781532 CA351545902 |
246 | V>F | No |
ClinGen TOPMed gnomAD |
|
|
rs1375781532 CA351545900 |
246 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1574956782 CA351545909 |
247 | Y>S | No |
ClinGen Ensembl |
|
|
CA2268313 rs79994970 |
249 | T>P | No |
ClinGen ExAC gnomAD |
|
|
rs758855513 CA2268315 |
255 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA351545977 rs1196596872 |
257 | L>F | No |
ClinGen gnomAD |
|
|
rs755821733 CA2268318 |
261 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs748718936 CA2268320 |
263 | R>* | No |
ClinGen ExAC gnomAD |
|
|
rs1471241843 CA351546027 |
266 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA351546038 rs1400003153 |
268 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1364995487 CA351546045 |
270 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1385736873 CA351546053 |
271 | G>S | No |
ClinGen gnomAD |
|
|
CA2268331 rs761829964 |
272 | A>S | Variant assessed as Somatic; 0.0003734 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs761829964 CA2268330 |
272 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA351546067 rs1257227979 |
274 | I>L | No |
ClinGen gnomAD |
|
| TCGA novel | 274 | I>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs763483440 CA351546074 |
275 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs763483440 CA2268333 |
275 | K>Q | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 279 | Y>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA351546131 rs1574956909 |
283 | T>P | No |
ClinGen Ensembl |
|
|
CA351546135 rs1487591288 |
283 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
CA2268337 rs182294541 |
284 | R>C | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA351546139 rs1268135744 |
284 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
| TCGA novel | 287 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA69767216 rs867860146 |
291 | W>* | No |
ClinGen Ensembl |
|
|
CA69767225 rs779996001 |
293 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs200333330 CA2268361 |
294 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA351546234 rs1282264670 |
296 | T>S | No |
ClinGen gnomAD |
|
|
CA351546273 rs1378139236 |
302 | Y>H | No |
ClinGen gnomAD |
|
|
rs1256837057 CA351546310 |
307 | G>A | No |
ClinGen TOPMed |
|
|
rs977467506 CA69767256 |
308 | A>T | No |
ClinGen TOPMed |
|
| TCGA novel | 309 | M>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA69767261 rs923056615 |
309 | M>V | No |
ClinGen TOPMed |
|
|
CA2268363 rs780969231 |
310 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA351546372 rs1218521623 |
317 | K>E | No |
ClinGen gnomAD |
|
|
CA351546376 rs1352953035 |
317 | K>M | No |
ClinGen Ensembl |
|
|
CA351546383 rs1395974786 |
318 | Y>C | No |
ClinGen gnomAD |
|
|
CA69767304 rs1043125862 |
320 | Y>C | No |
ClinGen Ensembl |
|
|
CA2268365 rs756343038 |
320 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
rs778046880 CA2268366 |
322 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752512226 CA2268384 |
325 | D>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2268385 rs756442467 |
333 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA351546506 rs1559310021 |
334 | S>T | No |
ClinGen Ensembl |
|
|
rs1021849751 CA69767558 |
339 | V>G | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 340 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA351546563 rs1440959522 |
343 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA351546570 rs1424383474 |
344 | I>V | No |
ClinGen gnomAD |
|
|
CA69767566 rs200681833 |
345 | F>C | No |
ClinGen 1000Genomes |
|
|
rs1459868058 CA351546617 |
351 | M>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
| TCGA novel | 352 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs757420710 CA2268388 |
356 | G>E | No |
ClinGen ExAC gnomAD |
|
|
rs1336517548 CA351546690 |
361 | D>V | No |
ClinGen gnomAD |
|
| TCGA novel | 364 | E>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs769012111 CA2268412 |
372 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA2268413 rs781533049 |
379 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs1033304540 CA69771677 |
380 | M>V | No |
ClinGen TOPMed gnomAD |
|
|
CA69771698 rs1011296537 |
384 | P>R | No |
ClinGen TOPMed |
|
|
CA2268416 rs141030841 |
384 | P>S | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1267212841 CA351546890 |
390 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
| TCGA novel | 390 | L>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1425397943 CA351546896 |
391 | F>L | No |
ClinGen gnomAD |
|
| rs1390226414 | 392 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1222131893 CA351546913 |
393 | I>F | No |
ClinGen TOPMed |
|
| rs1390226414 | 393 | I>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1574962260 CA351546974 |
402 | S>N | No |
ClinGen Ensembl |
|
|
rs1230075779 CA351547025 |
407 | V>A | No |
ClinGen TOPMed |
|
|
CA351547021 rs1482196989 |
407 | V>I | No |
ClinGen gnomAD |
|
|
CA2268443 rs761724380 |
411 | I>M | No |
ClinGen ExAC gnomAD |
|
|
CA351547102 rs1418587117 |
419 | P>T | No |
ClinGen gnomAD |
|
|
CA351547110 rs1308796937 |
420 | S>A | No |
ClinGen TOPMed |
|
|
CA351547116 rs1159833186 |
421 | F>L | No |
ClinGen gnomAD |
|
|
rs560112925 CA351547141 |
424 | K>N | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA351547148 rs1172409231 |
426 | Y>N | No |
ClinGen gnomAD |
|
|
rs763081342 CA2268446 |
427 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA69777054 rs981370054 |
428 | R>W | No |
ClinGen TOPMed |
|
|
rs1391469650 CA351547195 |
433 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs763840556 CA2268450 |
435 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs763840556 CA2268449 |
435 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2268452 rs141131824 |
438 | I>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs141131824 CA2268453 |
438 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA351547261 rs1196462270 |
443 | G>R | No |
ClinGen gnomAD |
|
|
rs757969440 CA2268455 |
445 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2268456 rs201003777 |
448 | T>M | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs780841499 CA2268476 |
451 | G>A | No |
ClinGen ExAC gnomAD |
|
|
rs1367433173 CA351547533 |
452 | M>V | No |
ClinGen gnomAD |
|
|
rs200356672 CA351547556 |
453 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs200356672 CA2268477 |
453 | Y>F | No |
ClinGen ExAC gnomAD |
|
|
CA2268478 rs769592190 |
458 | F>C | No |
ClinGen ExAC gnomAD |
|
|
rs773099960 CA2268479 |
461 | Y>H | No |
ClinGen ExAC |
|
|
CA351547708 rs1216056597 |
465 | G>S | No |
ClinGen gnomAD |
|
|
CA351547719 rs1351428708 |
466 | V>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA351547762 rs201130139 |
470 | W>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2268481 rs201130139 |
470 | W>C | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 471 | V>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs759752158 CA2268483 |
473 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 478 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1215052560 CA351547852 |
481 | W>S | No |
ClinGen gnomAD |
|
|
CA351547858 rs1242006847 |
482 | I>V | No |
ClinGen gnomAD |
|
|
CA69778761 rs1051579465 |
487 | N>D | No |
ClinGen TOPMed gnomAD |
|
|
CA2268496 rs752113333 |
488 | L>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs755610105 CA2268497 |
489 | Y>F | No |
ClinGen ExAC gnomAD |
|
|
rs1223953384 CA351548002 |
490 | D>G | No |
ClinGen TOPMed |
|
|
CA351547994 rs1262277575 |
490 | D>H | No |
ClinGen TOPMed |
|
|
rs1325900360 CA351548010 |
491 | G>R | No |
ClinGen TOPMed |
|
|
rs908141949 CA69778772 |
492 | I>M | No |
ClinGen TOPMed |
|
|
CA351548027 rs1268680274 |
492 | I>T | No |
ClinGen TOPMed |
|
|
rs942843351 CA69778779 |
493 | E>Q | No |
ClinGen TOPMed |
|
|
rs777593198 CA2268498 |
495 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1451100423 CA351548081 |
496 | I>V | No |
ClinGen TOPMed |
|
|
CA2268499 rs749190243 |
498 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs1402361794 CA351548113 |
499 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA2268500 rs770780822 |
499 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 500 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA2268502 rs746138760 CA351548131 |
501 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA69778812 rs919565499 |
502 | P>L | No |
ClinGen Ensembl |
|
| TCGA novel | 503 | W>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 507 | S>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA2268503 rs772252157 |
509 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2268504 rs775745972 |
510 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs1440194761 CA351548319 |
515 | L>P | No |
ClinGen gnomAD |
|
|
rs200367448 CA69778832 |
517 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen 1000Genomes NCI-TCGA gnomAD |
|
rs768726455 CA2268506 |
517 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA351548637 rs1397408078 |
519 | C>F | No |
ClinGen gnomAD |
|
|
rs763562406 CA2268534 |
523 | S>L | No |
ClinGen ExAC gnomAD |
|
|
rs554946637 CA2268537 |
525 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1227091577 CA351548749 |
526 | K>Q | No |
ClinGen gnomAD |
|
|
CA2268539 rs141254266 |
528 | V>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1280855809 CA351548871 |
533 | N>S | No |
ClinGen TOPMed |
|
|
CA351548877 rs1434198057 |
534 | K>E | No |
ClinGen TOPMed |
|
|
CA351548920 rs1349279779 |
535 | T>I | No |
ClinGen TOPMed |
|
|
rs755202696 CA2268542 |
537 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs1259512423 CA351549006 |
539 | P>R | No |
ClinGen gnomAD |
|
|
rs781165466 CA2268543 |
540 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA351549051 rs1373921382 |
543 | I>F | No |
ClinGen gnomAD |
|
|
rs141978861 CA351549054 |
543 | I>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA2268545 rs141978861 |
543 | I>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs771265506 CA2268548 |
548 | S>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 549 | L>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1383368652 CA351549127 |
549 | L>V | No |
ClinGen gnomAD |
|
|
CA351549157 rs1382019702 |
551 | L>F | No |
ClinGen gnomAD |
|
|
CA2268549 rs774758154 |
554 | M>V | No |
ClinGen ExAC gnomAD |
|
|
CA2268550 rs760287133 |
555 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs41284017 CA2268552 |
557 | V>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA2268553 rs200411977 |
560 | V>I | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs766133222 CA2268557 |
562 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs751335186 CA2268558 |
563 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs1329505618 CA351549364 |
564 | R>C | No |
ClinGen TOPMed |
|
|
rs369383563 CA351549367 |
564 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs369383563 CA2268559 |
564 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA351549372 rs1466454467 |
565 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
CA351549403 rs1182012855 |
567 | Q>K | No |
ClinGen gnomAD |
|
|
rs1038857154 CA69781618 |
567 | Q>R | No |
ClinGen TOPMed gnomAD |
|
|
CA69781629 rs901778371 |
569 | E>D | No |
ClinGen Ensembl |
|
|
CA2268560 rs781495760 |
571 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA351550368 rs1222744743 |
577 | K>Q | No |
ClinGen gnomAD |
|
|
CA2268590 rs769402505 |
577 | K>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA351550398 rs1574972868 |
578 | Y>S | No |
ClinGen Ensembl |
|
|
CA351550423 rs772809301 |
581 | T>I | No |
ClinGen ExAC gnomAD |
|
|
rs772809301 CA2268591 |
581 | T>N | No |
ClinGen ExAC gnomAD |
|
|
CA351550421 rs1574972886 |
581 | T>P | No |
ClinGen Ensembl |
|
| TCGA novel | 583 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs770286335 CA2268593 |
583 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1574972904 CA351550443 |
584 | E>D | No |
ClinGen Ensembl |
|
|
rs774349816 CA2268594 |
586 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA351550454 rs774349816 |
586 | N>T | No |
ClinGen ExAC gnomAD |
|
|
CA351550460 rs1479735023 |
587 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
rs376586731 CA2268595 |
587 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1574972957 CA351550480 |
590 | V>G | No |
ClinGen Ensembl |
|
|
rs767476496 CA2268596 |
590 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs564026953 CA69790611 |
591 | E>G | No |
ClinGen gnomAD |
|
|
CA2268598 rs370695700 |
592 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs550083440 CA2268599 |
592 | R>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs550083440 CA351550493 |
592 | R>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs368273326 CA2268601 |
593 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA2268602 rs368273326 |
593 | E>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1404239104 CA351550511 |
595 | A>V | No |
ClinGen gnomAD |
|
|
rs372250030 CA2268603 |
596 | T>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs758883547 CA2268604 |
597 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs938126566 CA69790707 |
597 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs758883547 CA2268605 |
597 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA69790714 rs376180429 |
600 | S>F | No |
ClinGen ESP TOPMed |
|
|
CA351550537 rs1307130432 |
600 | S>P | No |
ClinGen gnomAD |
|
|
CA2268607 rs748074723 |
601 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA2268608 rs748074723 |
601 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs200063855 CA2268609 |
601 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA351550550 rs200861169 |
603 | V>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs200861169 CA2268610 |
603 | V>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs200861169 CA2268611 |
603 | V>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA69790757 rs776524083 |
604 | M>V | No |
ClinGen TOPMed |
|
|
CA2268612 rs151175565 |
605 | N>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs146953899 CA2268614 |
606 | G>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 607 | A>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs770074983 CA2268616 |
607 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs776981870 CA2268617 |
608 | L>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs531399879 CA2268618 |
609 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA351550614 rs1158362031 |
613 | H>R | No |
ClinGen TOPMed |
|
|
rs367703038 CA2268620 |
614 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs534809733 CA2268621 |
615 | I>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1361587019 CA351550624 |
615 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
CA351550629 rs1357401215 |
616 | V>M | No |
ClinGen gnomAD |
|
|
CA351550635 rs1245266539 |
617 | E>K | No |
ClinGen gnomAD |
No associated diseases with P31641
No regional properties for P31641
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P31641 | |||
11 GO annotations of cellular component
| Name | Definition |
|---|---|
| apical plasma membrane | The region of the plasma membrane located at the apical end of the cell. |
| basolateral plasma membrane | The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. |
| dendrite | A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. |
| GABA-ergic synapse | A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| integral component of postsynaptic membrane | The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| microvillus membrane | The portion of the plasma membrane surrounding a microvillus. |
| neuronal cell body | The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| plasma membrane protein complex | Any protein complex that is part of the plasma membrane. |
7 GO annotations of molecular function
| Name | Definition |
|---|---|
| alanine transmembrane transporter activity | Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid. |
| amino acid transmembrane transporter activity | Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group. |
| amino acid:sodium symporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in). |
| gamma-aminobutyric acid transmembrane transporter activity | Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA). |
| gamma-aminobutyric acid:sodium symporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) + Cl-(out) = gamma-aminobutyric acid(in) + Na+(in) + Cl(in). |
| taurine transmembrane transporter activity | Enables the transfer of taurine from one side of a membrane to the other. Taurine (2-aminoethanesulfonic acid) is a sulphur-containing amino acid derivative which is important in the metabolism of fats. |
| taurine:sodium symporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in). |
13 GO annotations of biological process
| Name | Definition |
|---|---|
| alanine transport | The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| amino acid import across plasma membrane | The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol. |
| amino acid transport | The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| gamma-aminobutyric acid import | The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle. |
| import across plasma membrane | The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol. |
| modulation of chemical synaptic transmission | Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission. |
| neurotransmitter transport | The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. |
| nitrogen compound transport | The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| positive regulation of cell differentiation | Any process that activates or increases the frequency, rate or extent of cell differentiation. |
| positive regulation of necrotic cell death | Any process that increases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents. |
| sodium ion transmembrane transport | A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. |
| taurine transport | The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| transport across blood-brain barrier | The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier. |
26 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O18875 | SLC6A8 | Sodium- and chloride-dependent creatine transporter 1 | Bos taurus (Bovine) | PR |
| Q9MZ34 | SLC6A6 | Sodium- and chloride-dependent taurine transporter | Bos taurus (Bovine) | PR |
| Q00589 | SLC6A6 | Sodium- and chloride-dependent taurine transporter | Canis lupus familiaris (Dog) (Canis familiaris) | PR |
| Q9W4C5 | NAAT1 | Sodium-dependent nutrient amino acid transporter 1 | Drosophila melanogaster (Fruit fly) | PR |
| Q9Y345 | SLC6A5 | Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (Human) | PR |
| Q9UN76 | SLC6A14 | Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) | Homo sapiens (Human) | PR |
| P30531 | SLC6A1 | Sodium- and chloride-dependent GABA transporter 1 | Homo sapiens (Human) | PR |
| P48029 | SLC6A8 | Sodium- and chloride-dependent creatine transporter 1 | Homo sapiens (Human) | PR |
| Q9NSD5 | SLC6A13 | Sodium- and chloride-dependent GABA transporter 2 | Homo sapiens (Human) | PR |
| P48066 | SLC6A11 | Sodium- and chloride-dependent GABA transporter 3 | Homo sapiens (Human) | PR |
| Q9H2J7 | SLC6A15 | Sodium-dependent neutral amino acid transporter B(0)AT2 | Homo sapiens (Human) | PR |
| Q9H1V8 | SLC6A17 | Sodium-dependent neutral amino acid transporter SLC6A17 | Homo sapiens (Human) | PR |
| Q9GZN6 | SLC6A16 | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 | Homo sapiens (Human) | PR |
| P23975 | SLC6A2 | Sodium-dependent noradrenaline transporter | Homo sapiens (Human) | PR |
| P31650 | Slc6a11 | Sodium- and chloride-dependent GABA transporter 3 | Mus musculus (Mouse) | PR |
| P31648 | Slc6a1 | Sodium- and chloride-dependent GABA transporter 1 | Mus musculus (Mouse) | PR |
| Q9JMA9 | Slc6a14 | Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) | Mus musculus (Mouse) | PR |
| Q8VBW1 | Slc6a8 | Sodium- and chloride-dependent creatine transporter 1 | Mus musculus (Mouse) | PR |
| Q761V0 | Slc6a5 | Sodium- and chloride-dependent glycine transporter 2 | Mus musculus (Mouse) | PR |
| P31649 | Slc6a13 | Sodium- and chloride-dependent GABA transporter 2 | Mus musculus (Mouse) | PR |
| O35316 | Slc6a6 | Sodium- and chloride-dependent taurine transporter | Mus musculus (Mouse) | PR |
| P31647 | Slc6a11 | Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Rat) | PR |
| P23978 | Slc6a1 | Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Rat) | PR |
| P28570 | Slc6a8 | Sodium- and chloride-dependent creatine transporter 1 | Rattus norvegicus (Rat) | PR |
| O76689 | snf-6 | Sodium-dependent acetylcholine transporter | Caenorhabditis elegans | PR |
| G5EBN9 | snf-3 | Sodium- and chloride-dependent betaine transporter | Caenorhabditis elegans | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATKEKLQCL | KDFHKDILKP | SPGKSPGTRP | EDEAEGKPPQ | REKWSSKIDF | VLSVAGGFVG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LGNVWRFPYL | CYKNGGGAFL | IPYFIFLFGS | GLPVFFLEII | IGQYTSEGGI | TCWEKICPLF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SGIGYASVVI | VSLLNVYYIV | ILAWATYYLF | QSFQKELPWA | HCNHSWNTPH | CMEDTMRKNK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SVWITISSTN | FTSPVIEFWE | RNVLSLSPGI | DHPGSLKWDL | ALCLLLVWLV | CFFCIWKGVR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| STGKVVYFTA | TFPFAMLLVL | LVRGLTLPGA | GAGIKFYLYP | DITRLEDPQV | WIDAGTQIFF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SYAICLGAMT | SLGSYNKYKY | NSYRDCMLLG | CLNSGTSFVS | GFAIFSILGF | MAQEQGVDIA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DVAESGPGLA | FIAYPKAVTM | MPLPTFWSIL | FFIMLLLLGL | DSQFVEVEGQ | ITSLVDLYPS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FLRKGYRREI | FIAFVCSISY | LLGLTMVTEG | GMYVFQLFDY | YAASGVCLLW | VAFFECFVIA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| WIYGGDNLYD | GIEDMIGYRP | GPWMKYSWAV | ITPVLCVGCF | IFSLVKYVPL | TYNKTYVYPN |
| 550 | 560 | 570 | 580 | 590 | 600 |
| WAIGLGWSLA | LSSMLCVPLV | IVIRLCQTEG | PFLVRVKYLL | TPREPNRWAV | EREGATPYNS |
| 610 | |||||
| RTVMNGALVK | PTHIIVETMM |