Q9W4C5
PR
Gene name |
NAAT1 (CG3252) |
Protein name |
Sodium-dependent nutrient amino acid transporter 1 |
Names |
DmNAT1 |
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG3252 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9W4C5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9W4C5-F1 | Predicted | AlphaFoldDB |
No variants for Q9W4C5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9W4C5 | |||||
No associated diseases with Q9W4C5
No regional properties for Q9W4C5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9W4C5 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
6 GO annotations of molecular function
| Name | Definition |
|---|---|
| amino acid:cation symporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + cation(out) = amino acid(in) + cation(in). |
| amino acid:sodium symporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in). |
| D-amino acid transmembrane transporter activity | Enables the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids. |
| L-amino acid transmembrane transporter activity | Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids. |
| neurotransmitter transmembrane transporter activity | Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. |
| neutral amino acid transmembrane transporter activity | Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3. |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| amino acid transmembrane transport | The process in which an amino acid is transported across a membrane. |
| D-amino acid transport | The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| L-amino acid transport | The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| neurotransmitter transport | The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. |
| neutral amino acid transport | The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| sodium ion transmembrane transport | A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. |
| sodium ion transport | The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
21 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O18875 | SLC6A8 | Sodium- and chloride-dependent creatine transporter 1 | Bos taurus (Bovine) | PR |
| Q9MZ34 | SLC6A6 | Sodium- and chloride-dependent taurine transporter | Bos taurus (Bovine) | PR |
| P48029 | SLC6A8 | Sodium- and chloride-dependent creatine transporter 1 | Homo sapiens (Human) | PR |
| P48066 | SLC6A11 | Sodium- and chloride-dependent GABA transporter 3 | Homo sapiens (Human) | PR |
| P30531 | SLC6A1 | Sodium- and chloride-dependent GABA transporter 1 | Homo sapiens (Human) | PR |
| Q9NSD5 | SLC6A13 | Sodium- and chloride-dependent GABA transporter 2 | Homo sapiens (Human) | PR |
| P31641 | SLC6A6 | Sodium- and chloride-dependent taurine transporter | Homo sapiens (Human) | PR |
| Q9UN76 | SLC6A14 | Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) | Homo sapiens (Human) | PR |
| Q9Y345 | SLC6A5 | Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (Human) | PR |
| O35316 | Slc6a6 | Sodium- and chloride-dependent taurine transporter | Mus musculus (Mouse) | PR |
| P31650 | Slc6a11 | Sodium- and chloride-dependent GABA transporter 3 | Mus musculus (Mouse) | PR |
| P31648 | Slc6a1 | Sodium- and chloride-dependent GABA transporter 1 | Mus musculus (Mouse) | PR |
| Q8VBW1 | Slc6a8 | Sodium- and chloride-dependent creatine transporter 1 | Mus musculus (Mouse) | PR |
| P31649 | Slc6a13 | Sodium- and chloride-dependent GABA transporter 2 | Mus musculus (Mouse) | PR |
| Q9JMA9 | Slc6a14 | Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) | Mus musculus (Mouse) | PR |
| Q761V0 | Slc6a5 | Sodium- and chloride-dependent glycine transporter 2 | Mus musculus (Mouse) | PR |
| P31647 | Slc6a11 | Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Rat) | PR |
| P23978 | Slc6a1 | Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Rat) | PR |
| P28570 | Slc6a8 | Sodium- and chloride-dependent creatine transporter 1 | Rattus norvegicus (Rat) | PR |
| O76689 | snf-6 | Sodium-dependent acetylcholine transporter | Caenorhabditis elegans | PR |
| G5EBN9 | snf-3 | Sodium- and chloride-dependent betaine transporter | Caenorhabditis elegans | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MELKGVQPSN | GSSNGSGNGA | TNAASTEKTD | AEKPTAERTN | WGNGLEFLMS | CISVSVGLGN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VWRFPFTAYE | NGGGAFLIPY | IIVLFLIGKP | MYYLEMIMGQ | FTSQGTVKIW | SVVPGFVGVG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YGQAFGTICI | ISYYSSLLAL | TLYYLFVSFQ | SELPWSYCRD | EWTNCVNSRP | QEYVDNLLTG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VSLANESARN | LSGIVANDET | EKLQSSSELY | FLNVVIKEKL | DISDGVGDPD | WKLTLALFVA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| WVVIFLVIMR | GVKSSGKAAY | FLALFPYVVL | FVLLIRAVTL | EGARDGILFF | LEPQWGELLN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PTVWKEAVVQ | CFFSLAVGSG | PIIMFASYNR | FDHGIYRDAM | IVTTLDTLTS | LLGGITIFAI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LGNLAHNLQI | ENIRDVVRSG | TGLAFISYPD | AISKFQAVPQ | LFSVLFFFML | FVLGIGSIVA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LQSTIVTIIC | DQFKGWKYWK | VALTTSVCGF | LMGLVYVTPG | GQWILTLVDF | YGGTYVVFIL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AIFELAGIVW | VYGLQNFCDD | IEFMCNRRVS | LYWRVCWSFF | TPVMMIIIFI | YSMVTIEPIK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| YSELYFPEAA | NIAGWLLFAI | GAAQFPLWGL | WYISRHPQGT | YWKSLKASLK | PSDRWGPANP |
| 610 | 620 | 630 | 640 | ||
| EIRREWVIFK | NQKAAQRATQ | KDTSKLGFFW | RKVANFCGSN | K |