AiPD: Autoinhibited Protein Database

Gene name	DTX42
Protein name	Protein DETOXIFICATION 42
Names	AtDTX42, Aluminum-activated citrate transporter, AtMATE, FRD-like protein, Multidrug and toxic compound extrusion protein 42, MATE protein 42
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT1G51340
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

65-249 (Predicted disordered autoinhibitory region) PR

65-249 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9SYD6-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
ENSVATH13501747	12	P>S	No	1000Genomes
ENSVATH13501748	20	F>L	No	1000Genomes
ENSVATH04932690	35	E>G	No	1000Genomes
ENSVATH04932691	38	R>Q	No	1000Genomes
tmp_1_19032230_A_C	41	L>F	No	1000Genomes
ENSVATH14286176	64	I>T	No	1000Genomes
tmp_1_19032419_G_T	71	A>S	No	1000Genomes
tmp_1_19032479_G_A	91	V>I	No	1000Genomes
ENSVATH01343146	110	T>A	No	1000Genomes
ENSVATH04932696	114	H>Y	No	1000Genomes
ENSVATH13501776	124	N>D	No	1000Genomes
ENSVATH01343147	125	P>T	No	1000Genomes
ENSVATH01343148	127	E>Q	No	1000Genomes
ENSVATH01343149	130	I>K	No	1000Genomes
ENSVATH04932697	138	K>N	No	1000Genomes
ENSVATH04932703	157	P>L	No	1000Genomes
ENSVATH00092579	157	P>S	No	1000Genomes
ENSVATH13501782	158	P>S	No	1000Genomes
ENSVATH00092580	163	N>H	No	1000Genomes
tmp_1_19032811_A_C	173	I>L	No	1000Genomes
ENSVATH00092581	176	V>F	No	1000Genomes
ENSVATH13501784	200	H>N	No	1000Genomes
tmp_1_19032985_T_A	205	M>K	No	1000Genomes
tmp_1_19033056_C_T	229	Q>*	No	1000Genomes
ENSVATH13501808	270	A>V	No	1000Genomes
tmp_1_19033300_G_A	275	V>I	No	1000Genomes
ENSVATH13501811	295	I>M	No	1000Genomes
tmp_1_19033480_G_T	306	C>F	No	1000Genomes
ENSVATH01343166	324	F>I	No	1000Genomes
tmp_1_19033892_G_A	380	R>K	No	1000Genomes
ENSVATH14286180	380	R>S	No	1000Genomes
ENSVATH04932730	408	H>Q	No	1000Genomes
ENSVATH13501837	408	H>Y	No	1000Genomes
ENSVATH04932731	411	A>G	No	1000Genomes
ENSVATH00092588	413	V>A	No	1000Genomes
tmp_1_19034393_C_T	451	A>V	No	1000Genomes
tmp_1_19034413_G_C	458	A>P	No	1000Genomes
tmp_1_19034432_T_C	464	V>A	No	1000Genomes
tmp_1_19034517_G_T	492	M>I	No	1000Genomes
ENSVATH13501838	494	L>F	No	1000Genomes

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q9SYD6

		Description
EC Number
Subcellular Localization	Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
root hair	A long, thin projection from a root epidermal cell that contains F-actin and tubulin, and a cell wall.

Name	Definition
antiporter activity	Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).
citrate transmembrane transporter activity	Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of a membrane to the other.
xenobiotic transmembrane transporter activity	Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.

Name	Definition
citrate transport	The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
response to aluminum ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q9LPV4	DTX31	Protein DETOXIFICATION 31	Arabidopsis thaliana (Mouse-ear cress)	PR
F4I4Q3	DTX32	Protein DETOXIFICATION 32	Arabidopsis thaliana (Mouse-ear cress)	PR
F4HPH1	DTX22	Protein DETOXIFICATION 22	Arabidopsis thaliana (Mouse-ear cress)	PR
Q8W488	DTX21	Protein DETOXIFICATION 21	Arabidopsis thaliana (Mouse-ear cress)	PR
F4HQ05	DTX8	Protein DETOXIFICATION 8	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9C994	DTX14	Protein DETOXIFICATION 14	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9SIA5	DTX1	Protein DETOXIFICATION 1	Arabidopsis thaliana (Mouse-ear cress)	PR
O49660	DTX56	Protein DETOXIFICATION 56	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9FNC1	DTX28	Protein DETOXIFICATION 28	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9FHB6	DTX16	Protein DETOXIFICATION 16	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9FKQ1	DTX27	Protein DETOXIFICATION 27	Arabidopsis thaliana (Mouse-ear cress)	PR