AiPD: Autoinhibited Protein Database

Gene name	LA1 (At4g32720, F4D11.80)
Protein name	La protein 1
Names	AtLa1
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT4G32720
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

218-292 (Predicted disordered autoinhibitory region) PR

218-292 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q93ZV7-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
tmp_4_15787500_A_C	29	I>L	No	1000Genomes
tmp_4_15787729_A_G	72	E>G	No	1000Genomes
tmp_4_15787762_G_A	83	R>Q	No	1000Genomes
ENSVATH12355311	103	L>V	No	1000Genomes
ENSVATH00548961	123	F>L	No	1000Genomes
tmp_4_15788191_T_G	134	S>A	No	1000Genomes
tmp_4_15788192_C_T	134	S>F	No	1000Genomes
tmp_4_15788322_G_A	147	M>I	No	1000Genomes
ENSVATH06813895	153	E>G	No	1000Genomes
tmp_4_15788606_A_T	204	K>N	No	1000Genomes
ENSVATH14328089	205	F>L	No	1000Genomes
tmp_4_15788637_G_A	215	A>T	No	1000Genomes
tmp_4_15788674_C_T	227	S>F	No	1000Genomes
tmp_4_15788688_G_A	232	D>N	No	1000Genomes
tmp_4_15788838_C_T	252	T>M	No	1000Genomes
ENSVATH06813901	288	A>T	No	1000Genomes
tmp_4_15788960_G_A	293	D>N	No	1000Genomes
ENSVATH00548965	328	D>N	No	1000Genomes
tmp_4_15789236_G_A	350	A>T	No	1000Genomes
ENSVATH14328090	367	A>P	No	1000Genomes
tmp_4_15789604_G_T	408	R>I	No	1000Genomes
ENSVATH06813911	417	G>*	No	1000Genomes
tmp_4_15789652_G_A	424	R>H	No	1000Genomes
ENSVATH06813913	425	W>R	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	Bicarbonate transporter-like, transmembrane domain	441 - 955	IPR011531
domain	Band 3 cytoplasmic domain	138 - 387	IPR013769

		Description
EC Number
Subcellular Localization	Nucleus, nucleoplasm Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
nucleolus	A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
plant-type cell wall	A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances.
ribonucleoprotein complex	A macromolecular complex that contains both RNA and protein molecules.

Name	Definition
mRNA binding	Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA binding	Binding to an RNA molecule or a portion thereof.

Name	Definition
embryo development ending in seed dormancy	The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
ncRNA processing	Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules.
ribosome biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
rRNA processing	Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
tRNA processing	The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P33399	LHP1	La protein homolog	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	PR
Q8N9W6	BOLL	Protein boule-like	Homo sapiens (Human)	PR
P42696	RBM34	RNA-binding protein 34	Homo sapiens (Human)	PR
Q4G0J3	LARP7	La-related protein 7	Homo sapiens (Human)	PR
P05455	SSB	Lupus La protein	Homo sapiens (Human)	PR
Q924M5	Boll	Protein boule-like	Mus musculus (Mouse)	PR
Q8C854	Myef2	Myelin expression factor 2	Mus musculus (Mouse)	PR
Q05CL8	Larp7	La-related protein 7	Mus musculus (Mouse)	PR
Q5XI01	Larp7	La-related protein 7	Rattus norvegicus (Rat)	PR
Q9S7N9	CID12	Polyadenylate-binding protein-interacting protein 12	Arabidopsis thaliana (Mouse-ear cress)	PR
Q4KM14	trnau1apl	tRNA selenocysteine 1-associated protein 1-like	Danio rerio (Zebrafish) (Brachydanio rerio)	PR