Q924M5
Gene name |
Boll |
Protein name |
Protein boule-like |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:75388 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q924M5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q924M5-F1 | Predicted | AlphaFoldDB |
12 variants for Q924M5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3388470648 | 35 | S>N | No | EVA | |
| rs3388473052 | 36 | G>A | No | EVA | |
| rs3388470387 | 52 | I>T | No | EVA | |
| rs3388469521 | 61 | L>V | No | EVA | |
| rs265463992 | 95 | Q>K | No | EVA | |
| rs3388469505 | 110 | Y>H | No | EVA | |
| rs3388470084 | 193 | Y>H | No | EVA | |
| rs252664365 | 213 | S>P | No | EVA | |
| rs3389988297 | 277 | M>K | No | EVA | |
| rs3390002655 | 277 | M>L | No | EVA | |
| rs3389953595 | 278 | P>A | No | EVA | |
| rs3390006857 | 284 | P>A | No | EVA |
No associated diseases with Q924M5
1 regional properties for Q924M5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Mad3/Bub1 homology region 1 | 55 - 226 | IPR013212 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| identical protein binding | Binding to an identical protein or proteins. |
| mRNA 3'-UTR binding | Binding to a 3' untranslated region of an mRNA molecule. |
| translation activator activity | Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| 3'-UTR-mediated mRNA stabilization | An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA. |
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| meiotic cell cycle | Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. |
| positive regulation of translational initiation | Any process that activates or increases the frequency, rate or extent of translational initiation. |
| spermatogenesis | The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. |
8 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P42696 | RBM34 | RNA-binding protein 34 | Homo sapiens (Human) | PR |
| Q8N9W6 | BOLL | Protein boule-like | Homo sapiens (Human) | PR |
| Q05CL8 | Larp7 | La-related protein 7 | Mus musculus (Mouse) | PR |
| Q8C854 | Myef2 | Myelin expression factor 2 | Mus musculus (Mouse) | PR |
| Q5XI01 | Larp7 | La-related protein 7 | Rattus norvegicus (Rat) | PR |
| Q9S7N9 | CID12 | Polyadenylate-binding protein-interacting protein 12 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q93ZV7 | LA1 | La protein 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q4KM14 | trnau1apl | tRNA selenocysteine 1-associated protein 1-like | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| METESRAQST | NQTQTDSLSP | SPNPVSPVPL | NNPTSGPRYG | TVIPNRIFVG | GIDFKTNEND |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LRKFFSQYGS | VKEVKIVNDR | AGVSKGYGFI | TFETQEDAQK | ILQEAEKLNY | KDKKLNIGPA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IRKQQVGIPR | SSLMPAAGTM | YLTTSTGYPY | TYHNGVAYFH | TPEVTSVPPS | WPSRSISSSP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VMVAQPVYQQ | PAYHYQAPAQ | CLPGQWQWGV | PQSPASSAPF | LYLQPSEVIY | QPVEIAQDGG |
| 250 | 260 | 270 | 280 | 290 | |
| CVPPPLSLME | TSVPEPYSDH | GVQAAYHQVY | ASSAIAMPAP | MMQPEPIKVR | SLF |