Q8N9W6
PR
Gene name |
BOLL (BOULE) |
Protein name |
Protein boule-like |
Names |
|
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:66037 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8N9W6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8N9W6-F1 | Predicted | AlphaFoldDB |
195 variants for Q8N9W6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA2045130 rs61732251 |
2 | Q>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1305759786 CA350383411 |
2 | Q>R | No |
ClinGen TOPMed |
|
|
CA350383401 rs1184846631 |
4 | D>H | No |
ClinGen TOPMed gnomAD |
|
|
CA2045129 rs115292776 |
4 | D>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA350383391 rs1208798087 |
5 | S>* | No |
ClinGen gnomAD |
|
| TCGA novel | 5 | S>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 5 | S>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA63565920 rs961844032 |
7 | S>C | No |
ClinGen TOPMed |
|
|
CA2045127 rs141986181 |
9 | S>Y | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA350383365 rs754347465 |
10 | P>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2045126 rs754347465 |
10 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA350383356 rs1286206965 |
11 | N>S | No |
ClinGen gnomAD |
|
|
COSM1014565 rs761048419 CA2045125 COSM1014566 |
12 | P>S | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA2045124 rs761048419 |
12 | P>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA2045123 rs773500620 |
13 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs1360997218 CA350383327 |
16 | V>G | No |
ClinGen gnomAD |
|
|
rs140394268 CA63565845 |
16 | V>M | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA350383309 rs1417796845 |
19 | N>S | No |
ClinGen TOPMed |
|
|
rs762007977 CA2045121 |
20 | N>I | No |
ClinGen ExAC gnomAD |
|
|
rs1456890221 CA350383292 |
22 | T>A | No |
ClinGen gnomAD |
|
|
rs774476981 CA2045120 |
22 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1456890221 CA350383291 |
22 | T>P | No |
ClinGen gnomAD |
|
|
rs768635166 CA2045119 |
23 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2045118 rs749175418 |
23 | S>R | No |
ClinGen ExAC gnomAD |
|
|
rs775602017 CA2045117 |
25 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA350383265 rs1471500906 |
26 | R>S | No |
ClinGen gnomAD |
|
|
rs536465928 CA2045116 |
26 | R>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA350383246 rs1244470996 |
29 | T>I | No |
ClinGen gnomAD |
|
|
rs745623797 CA2045115 |
31 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA2045114 rs377264153 |
34 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA350383216 rs1265929699 |
34 | R>H | No |
ClinGen gnomAD |
|
|
rs1265929699 CA350383214 |
34 | R>L | No |
ClinGen gnomAD |
|
|
CA2045112 rs746650488 |
37 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs777269851 CA2045111 COSM718635 |
38 | G>A | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA350383185 rs1381310177 |
39 | G>E | No |
ClinGen gnomAD |
|
|
rs553910561 CA2045110 |
40 | I>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA350383171 rs1464564258 |
41 | D>V | No |
ClinGen TOPMed |
|
|
CA350216491 rs1292117671 |
44 | T>K | No |
ClinGen gnomAD |
|
|
COSM1404323 rs778462794 COSM1404322 CA2045089 |
46 | E>K | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs778462794 CA63733262 |
46 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2045088 rs761940825 |
47 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs1428471901 CA350216460 |
49 | L>V | No |
ClinGen gnomAD |
|
|
CA350216440 rs1167355957 |
51 | K>N | No |
ClinGen gnomAD |
|
|
CA350216439 rs750907998 |
52 | F>I | No |
ClinGen ExAC gnomAD |
|
|
rs750907998 CA2045087 |
52 | F>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 53 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs1428711101 | 54 | S>P | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1424108657 CA350216407 |
56 | Y>C | No |
ClinGen gnomAD |
|
|
rs1490783289 CA350216402 |
57 | G>R | No |
ClinGen gnomAD |
|
|
CA350216393 rs1574868065 |
58 | S>Y | No |
ClinGen Ensembl |
|
|
rs1204387881 CA350216338 |
66 | N>S | No |
ClinGen gnomAD |
|
|
CA2045085 rs757597509 |
69 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs751758762 CA2045084 |
71 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs1311826563 CA350216287 |
72 | S>Y | No |
ClinGen gnomAD |
|
|
CA2045083 rs377038167 |
73 | K>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs577424738 COSM1404320 COSM1404321 CA2045072 |
78 | V>I | salivary_gland large_intestine breast [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD |
|
rs1558997200 CA350216227 |
79 | T>A | No |
ClinGen Ensembl |
|
|
CA350216225 rs1391397080 |
79 | T>N | No |
ClinGen TOPMed gnomAD |
|
|
rs1391397080 CA350216224 |
79 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
CA2045071 rs778337759 |
82 | T>P | No |
ClinGen ExAC gnomAD |
|
|
CA2045069 rs746350560 |
83 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs906554146 CA63732419 |
85 | D>V | No |
ClinGen TOPMed |
|
|
CA2045067 rs757834928 |
86 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA2045066 rs751862100 |
88 | K>T | No |
ClinGen ExAC gnomAD |
|
|
CA350216159 rs1365410986 |
89 | I>L | No |
ClinGen gnomAD |
|
|
CA350216132 rs1472603644 |
92 | E>V | No |
ClinGen TOPMed |
|
|
CA2045052 rs200336393 |
93 | A>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA2045051 rs774026616 |
94 | E>G | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 96 | L>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA350215976 rs1251303226 |
98 | Y>C | No |
ClinGen TOPMed |
|
|
CA63731849 rs749281445 |
105 | I>V | No |
ClinGen Ensembl |
|
|
CA350215908 rs1209662890 |
108 | A>T | No |
ClinGen gnomAD |
|
|
rs779657994 CA2045047 |
108 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs985863702 CA63731838 |
110 | R>K | No |
ClinGen TOPMed gnomAD |
|
|
rs747527656 CA2045045 |
114 | V>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 115 | G>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA2045027 rs773876427 |
119 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1231357650 CA350214457 |
120 | S>G | No |
ClinGen gnomAD |
|
|
rs201051448 CA2045026 |
120 | S>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1444386001 CA350214439 |
121 | I>V | No |
ClinGen gnomAD |
|
|
CA63730180 rs368770987 |
122 | M>V | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA63730176 rs933779933 |
123 | P>L | No |
ClinGen Ensembl |
|
|
CA2045025 rs748492405 |
125 | A>G | No |
ClinGen ExAC gnomAD |
|
|
rs755142681 CA2045023 |
126 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs1177579366 CA350214342 |
127 | T>I | No |
ClinGen gnomAD |
|
| TCGA novel | 128 | M>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1457054155 CA350214262 |
132 | T>N | No |
ClinGen gnomAD |
|
|
rs1271659816 CA350214229 |
134 | T>A | No |
ClinGen TOPMed |
|
|
CA2045022 rs149921275 |
136 | Y>* | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs779934078 CA2045021 |
137 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs921014323 CA63730141 |
138 | Y>* | No |
ClinGen TOPMed |
|
| TCGA novel | 140 | Y>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 141 | H>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs975681893 CA63730137 |
141 | H>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA350214053 rs1574858443 |
143 | G>D | No |
ClinGen Ensembl |
|
|
CA350214022 rs1278089537 |
145 | A>V | No |
ClinGen TOPMed |
|
|
CA350213963 rs1486397092 |
149 | T>I | No |
ClinGen TOPMed |
|
|
CA350213959 rs1182487724 |
150 | P>S | No |
ClinGen gnomAD |
|
|
rs1203999953 CA350213895 |
153 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
COSM1404318 CA2045019 COSM1404319 rs750315080 |
154 | S>L | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA2045015 rs763959371 |
156 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA350213838 rs762441343 |
157 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs762441343 CA2045014 |
157 | P>Q | No |
ClinGen ExAC gnomAD |
|
|
rs753383912 CA2044992 |
162 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA350212440 rs1432014139 |
162 | R>H | Variant assessed as Somatic; 9.252e-05 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA350212435 rs1432014139 |
162 | R>L | No |
ClinGen TOPMed gnomAD |
|
|
CA2044993 COSM718639 rs753383912 |
162 | R>S | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs372809620 CA63728060 |
164 | V>A | No |
ClinGen ESP TOPMed |
|
|
CA2044991 rs766002606 |
164 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA350212402 rs143157211 |
165 | C>G | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA63728056 rs143157211 |
165 | C>R | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA2044990 rs762343625 |
166 | S>R | No |
ClinGen ExAC gnomAD |
|
|
rs1574851048 CA350212323 |
169 | V>G | No |
ClinGen Ensembl |
|
|
CA350212334 rs1483773906 |
169 | V>M | No |
ClinGen gnomAD |
|
|
CA63728047 rs896306425 |
170 | M>I | No |
ClinGen TOPMed |
|
|
rs774954759 CA2044989 |
170 | M>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA350212312 rs1417016670 |
170 | M>T | No |
ClinGen gnomAD |
|
|
rs774954759 CA350212317 |
170 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1241357648 CA350212288 |
172 | A>P | No |
ClinGen TOPMed |
|
|
CA63728043 rs1034931131 |
172 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA350212276 rs1486081993 |
173 | Q>K | No |
ClinGen gnomAD |
|
|
CA2044988 rs149053508 |
174 | P>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs61642236 CA63728017 |
175 | I>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs61642236 CA2044986 |
175 | I>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs139427403 CA2044985 |
176 | Y>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1168240424 CA350212182 |
178 | Q>H | No |
ClinGen TOPMed |
|
|
rs1226863820 CA350212169 |
179 | P>L | No |
ClinGen gnomAD |
|
|
CA350212158 rs1559411184 |
180 | A>E | No |
ClinGen Ensembl |
|
|
rs746150874 CA2044984 |
181 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA350212086 rs1402299365 |
184 | Q>E | No |
ClinGen TOPMed |
|
|
CA63723882 rs1047570451 |
185 | A>D | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 185 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1469620979 CA350210689 |
190 | L>* | No |
ClinGen TOPMed |
|
|
rs199838771 CA2044946 |
190 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs777017173 CA2044945 |
191 | P>S | No |
ClinGen ExAC |
|
|
CA350210644 rs1262746156 |
196 | W>C | No |
ClinGen Ensembl |
|
|
CA63723841 rs147772767 |
196 | W>G | No |
ClinGen ESP ExAC gnomAD |
|
|
CA2044944 rs147772767 |
196 | W>R | No |
ClinGen ESP ExAC gnomAD |
|
|
rs865850670 CA63723840 |
198 | V>F | No |
ClinGen Ensembl |
|
|
rs760862723 CA2044943 |
199 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA2044931 rs756735511 |
204 | S>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1574837614 CA350210567 |
207 | P>S | No |
ClinGen Ensembl |
|
|
rs1356604754 CA350210552 |
209 | L>S | No |
ClinGen gnomAD |
|
|
CA350210547 rs1302213585 |
210 | Y>H | No |
ClinGen TOPMed |
|
|
CA2044928 rs755544199 |
212 | Q>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1339680520 CA350210532 |
212 | Q>R | No |
ClinGen gnomAD |
|
| TCGA novel | 214 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 215 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1328016928 CA350210515 |
215 | E>Q | No |
ClinGen gnomAD |
|
|
CA350210455 rs1320915517 |
223 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
rs766665322 CA2044926 |
225 | Q>K | No |
ClinGen ExAC gnomAD |
|
|
CA350210438 rs1404237853 |
226 | D>H | No |
ClinGen gnomAD |
|
|
CA2044925 rs760884201 |
227 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs1305029704 CA350210395 |
232 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1395970693 CA350210390 |
233 | P>L | No |
ClinGen gnomAD |
|
|
rs560852404 CA2044924 |
233 | P>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA2044922 rs761963473 |
234 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2044923 rs761963473 |
234 | L>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774616057 CA2044921 |
235 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA2044920 rs768713144 |
237 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs140027779 CA63723380 |
238 | E>G | No |
ClinGen ESP TOPMed gnomAD |
|
| TCGA novel | 239 | T>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1200870892 CA350210350 |
240 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA2044900 rs751679778 |
246 | S>P | No |
ClinGen ExAC gnomAD |
|
|
rs1235719647 CA350209394 |
248 | H>Q | No |
ClinGen TOPMed |
|
|
CA63713247 rs867709728 |
250 | V>F | No |
ClinGen Ensembl |
|
|
rs986619330 CA63713245 |
252 | A>E | No |
ClinGen gnomAD |
|
|
CA350209355 rs762920202 |
255 | H>D | No |
ClinGen ExAC gnomAD |
|
|
CA2044897 rs775325443 |
255 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
CA2044898 rs762920202 |
255 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs946892434 CA63713242 |
257 | V>I | No |
ClinGen Ensembl |
|
|
CA63713236 rs915401766 |
259 | A>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA350209324 rs915401766 |
259 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs375573791 CA2044896 |
261 | S>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1447074543 CA350209297 |
264 | T>P | No |
ClinGen TOPMed |
|
|
CA350209294 rs1441018135 |
264 | T>S | No |
ClinGen gnomAD |
|
|
rs759218045 CA2044895 |
265 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA350209273 rs372015936 |
267 | A>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA2044894 rs372015936 |
267 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA350209272 rs1238964559 |
268 | P>S | No |
ClinGen gnomAD |
|
|
CA350209266 rs989721357 |
269 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
CA63713190 rs989721357 |
269 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
rs368659245 CA2044892 |
270 | M>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs142061895 CA2044891 |
271 | Q>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1230611424 CA350209244 |
272 | P>A | No |
ClinGen TOPMed |
|
|
rs1355474482 CA350209243 |
272 | P>H | No |
ClinGen TOPMed gnomAD |
|
|
CA350209239 rs1344560279 COSM3798479 COSM3798478 |
273 | E>Q | urinary_tract [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
CA2044890 rs771602159 |
274 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA2044889 rs749746878 |
275 | I>M | No |
ClinGen ExAC gnomAD |
|
|
CA350208403 rs1559384711 |
278 | V>A | No |
ClinGen Ensembl |
|
|
rs773979592 CA2044863 |
279 | W>* | No |
ClinGen ExAC gnomAD |
|
|
rs773979592 CA2044864 |
279 | W>C | No |
ClinGen ExAC gnomAD |
|
|
rs1268108782 CA350208387 |
280 | S>N | No |
ClinGen gnomAD |
|
|
CA350208388 rs1268108782 |
280 | S>T | No |
ClinGen gnomAD |
|
|
CA2044862 rs1135815 |
282 | H>Y | No |
ClinGen ExAC |
No associated diseases with Q8N9W6
1 regional properties for Q8N9W6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Glycosyl hydrolases family 1, N-terminal conserved site | 48 - 62 | IPR033132 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| identical protein binding | Binding to an identical protein or proteins. |
| mRNA 3'-UTR binding | Binding to a 3' untranslated region of an mRNA molecule. |
| translation activator activity | Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| 3'-UTR-mediated mRNA stabilization | An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA. |
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| meiotic cell cycle | Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. |
| positive regulation of translational initiation | Any process that activates or increases the frequency, rate or extent of translational initiation. |
| spermatogenesis | The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. |
8 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P42696 | RBM34 | RNA-binding protein 34 | Homo sapiens (Human) | PR |
| Q05CL8 | Larp7 | La-related protein 7 | Mus musculus (Mouse) | PR |
| Q8C854 | Myef2 | Myelin expression factor 2 | Mus musculus (Mouse) | PR |
| Q924M5 | Boll | Protein boule-like | Mus musculus (Mouse) | PR |
| Q5XI01 | Larp7 | La-related protein 7 | Rattus norvegicus (Rat) | PR |
| Q9S7N9 | CID12 | Polyadenylate-binding protein-interacting protein 12 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q93ZV7 | LA1 | La protein 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q4KM14 | trnau1apl | tRNA selenocysteine 1-associated protein 1-like | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQTDSLSPSP | NPVSPVPLNN | PTSAPRYGTV | IPNRIFVGGI | DFKTNESDLR | KFFSQYGSVK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EVKIVNDRAG | VSKGYGFVTF | ETQEDAQKIL | QEAEKLNYKD | KKLNIGPAIR | KQQVGIPRSS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IMPAAGTMYL | TTSTGYPYTY | HNGVAYFHTP | EVTSVPPPWP | SRSVCSSPVM | VAQPIYQQPA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YHYQATTQYL | PGQWQWSVPQ | PSASSAPFLY | LQPSEVIYQP | VEIAQDGGCV | PPPLSLMETS |
| 250 | 260 | 270 | 280 | ||
| VPEPYSDHGV | QATYHQVYAP | SAITMPAPVM | QPEPIKTVWS | IHY |