Q91XT6

PR
Gene name
Tc2n (Mtac2d1)
Protein name
Tandem C2 domains nuclear protein
Names
Membrane targeting tandem C2 domain-containing protein 1, Tandem C2 protein in nucleus, Tac2-N
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:74413
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

138-246 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q91XT6

Entry ID Method Resolution Chain Position Source
AF-Q91XT6-F1 Predicted AlphaFoldDB

13 variants for Q91XT6

Variant ID(s) Position Change Description Diseaes Association Provenance
rs32998864 35 S>N No EVA
rs3389213907 35 S>R No EVA
rs3402984120 124 D>N No EVA
rs3389241894 156 V>D No EVA
rs3389187256 180 S>* No EVA
rs32993995 181 S>T No EVA
rs227533264 185 I>T No EVA
rs222620246 221 R>K No EVA
rs32996157 235 S>L No EVA
rs253599876 235 S>P No EVA
rs3389224098 275 F>I No EVA
rs256539463 336 E>D No EVA
rs237619161 343 A>P No EVA

No associated diseases with Q91XT6

4 regional properties for Q91XT6

Type Name Position InterPro Accession
domain C2 domain 222 - 341 IPR000008-1
domain C2 domain 343 - 472 IPR000008-2
domain Tandem C2 domains nuclear protein, C2A domain 239 - 341 IPR037786
domain Tandem C2 domains nuclear protein, C2B domain 352 - 486 IPR037788

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

45 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P48018 SYT1 Synaptotagmin-1 Bos taurus (Bovine) PR
P21521 Syt1 Synaptotagmin 1 Drosophila melanogaster (Fruit fly) PR
Q7L8C5 SYT13 Synaptotagmin-13 Homo sapiens (Human) PR
Q6XYQ8 SYT10 Synaptotagmin-10 Homo sapiens (Human) PR
Q9H2B2 SYT4 Synaptotagmin-4 Homo sapiens (Human) PR
P21579 SYT1 Synaptotagmin-1 Homo sapiens (Human) PR
Q86XP0 PLA2G4D Cytosolic phospholipase A2 delta Homo sapiens (Human) PR
Q9HCH5 SYTL2 Synaptotagmin-like protein 2 Homo sapiens (Human) PR
Q86SS6 SYT9 Synaptotagmin-9 Homo sapiens (Human) PR
Q9BQG1 SYT3 Synaptotagmin-3 Homo sapiens (Human) PR
O00445 SYT5 Synaptotagmin-5 Homo sapiens (Human) PR
Q9BT88 SYT11 Synaptotagmin-11 Homo sapiens (Human) PR
Q96C24 SYTL4 Synaptotagmin-like protein 4 Homo sapiens (Human) PR
Q9BQS2 SYT15 Synaptotagmin-15 Homo sapiens (Human) PR
Q8TDW5 SYTL5 Synaptotagmin-like protein 5 Homo sapiens (Human) PR
Q8IYJ3 SYTL1 Synaptotagmin-like protein 1 Homo sapiens (Human) PR
O43581 SYT7 Synaptotagmin-7 Homo sapiens (Human) PR
Q5T7P8 SYT6 Synaptotagmin-6 Homo sapiens (Human) PR
Q8N9U0 TC2N Tandem C2 domains nuclear protein Homo sapiens (Human) PR
P40749 Syt4 Synaptotagmin-4 Mus musculus (Mouse) PR
Q9EQT6 Syt13 Synaptotagmin-13 Mus musculus (Mouse) PR
Q9R0N4 Syt10 Synaptotagmin-10 Mus musculus (Mouse) PR
Q99N80 Sytl1 Synaptotagmin-like protein 1 Mus musculus (Mouse) PR
Q9R0Q1 Sytl4 Synaptotagmin-like protein 4 Mus musculus (Mouse) PR
Q8C6N3 Syt15 Synaptotagmin-15 Mus musculus (Mouse) PR
Q920N7 Syt12 Synaptotagmin-12 Mus musculus (Mouse) PR
Q80T23 Sytl5 Synaptotagmin-like protein 5 Mus musculus (Mouse) PR
Q9R0N5 Syt5 Synaptotagmin-5 Mus musculus (Mouse) PR
Q9R0N9 Syt9 Synaptotagmin-9 Mus musculus (Mouse) PR
Q9R0N8 Syt6 Synaptotagmin-6 Mus musculus (Mouse) PR
Q50L43 Pla2g4d Cytosolic phospholipase A2 delta Mus musculus (Mouse) PR
P46096 Syt1 Synaptotagmin-1 Mus musculus (Mouse) PR
Q9R0N3 Syt11 Synaptotagmin-11 Mus musculus (Mouse) PR
O35681 Syt3 Synaptotagmin-3 Mus musculus (Mouse) PR
P46097 Syt2 Synaptotagmin-2 Mus musculus (Mouse) PR
Q812E4 Sytl5 Synaptotagmin-like protein 5 Rattus norvegicus (Rat) PR
Q925B5 Syt13 Synaptotagmin-13 Rattus norvegicus (Rat) PR
O08625 Syt10 Synaptotagmin-10 Rattus norvegicus (Rat) PR
P47861 Syt5 Synaptotagmin-5 Rattus norvegicus (Rat) PR
Q62746 Syt6 Synaptotagmin-6 Rattus norvegicus (Rat) PR
P97610 Syt12 Synaptotagmin-12 Rattus norvegicus (Rat) PR
P40748 Syt3 Synaptotagmin-3 Rattus norvegicus (Rat) PR
Q925C0 Syt9 Synaptotagmin-9 Rattus norvegicus (Rat) PR
P59926 Syt15 Synaptotagmin-15 Rattus norvegicus (Rat) PR
P21707 Syt1 Synaptotagmin-1 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MAAEFIKSCC RGCLYGETEK QKFSVDRDFK ASASSSQNTI GIPPLTSVLV KPQVGCNEDY
70 80 90 100 110 120
LLSKLPCDGK EVQFVVPRFK LSYIQPRTQG IPSHLDELEG SARASFGDQK TELCSSFYHG
130 140 150 160 170 180
PSYDVYNPCY MYQHFSPDLS RRFLPHCETK QLYGSVCDLR TSKLPGSSGL SKSMLDLTTS
190 200 210 220 230 240
SQRFIQRHDS FSSVPSSSSS RKNSQGSNRS LDTITLSGDE RDLGRLNVKL FYNSSAEQIW
250 260 270 280 290 300
ITVLQCRDIS WPSSYGDTPT ISIKGILTLS KPVHFKSSAK EGSNAIEFME TFVFAIKLQN
310 320 330 340 350 360
LQAVRLAFKI QTQTPKKKTI GECSLSLRTL STQEMEYSLE IIAPSKISVC QAELELGTCF
370 380 390 400 410 420
QAVNSRIQLQ ILEAQYLPSS STPLTLSFFV KVGMFSSGEL IYKKKTRLLK ASSGRVKWGE
430 440 450 460 470 480
TMIFPLIQTE KEIVFLIKLY SRSSVRRKHF VGQLWISEDS NNIEAVNQWK ETITNPEKVV
IKWHKLNPS