Q84W41
PR
Gene name |
GLR3.6 (At3g51480, F26O13.120) |
Protein name |
Glutamate receptor 3.6 |
Names |
Ligand-gated ion channel 3.6 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G51480 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q84W41
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q84W41-F1 | Predicted | AlphaFoldDB |
50 variants for Q84W41
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_19101281_T_C | 9 | I>T | No | 1000Genomes | |
| ENSVATH02490801 | 13 | A>V | No | 1000Genomes | |
| tmp_3_19101442_A_G | 63 | I>V | No | 1000Genomes | |
| tmp_3_19101869_G_C | 111 | A>P | No | 1000Genomes | |
| tmp_3_19101902_C_A | 122 | L>I | No | 1000Genomes | |
| ENSVATH12709808 | 132 | S>F | No | 1000Genomes | |
| ENSVATH02490829 | 133 | P>S | No | 1000Genomes | |
| tmp_3_19101974_G_A | 146 | D>N | No | 1000Genomes | |
| tmp_3_19101989_G_C | 151 | A>P | No | 1000Genomes | |
| ENSVATH00414641 | 153 | I>T | No | 1000Genomes | |
| tmp_3_19102031_G_C | 165 | V>L | No | 1000Genomes | |
| ENSVATH02490830 | 176 | R>Q | No | 1000Genomes | |
| tmp_3_19102206_T_A | 223 | I>N | No | 1000Genomes | |
| ENSVATH06294947 | 238 | V>M | No | 1000Genomes | |
| ENSVATH06294948 | 240 | R>Q | No | 1000Genomes | |
| ENSVATH14419933 | 273 | N>D | No | 1000Genomes | |
| ENSVATH06294950 | 284 | H>Y | No | 1000Genomes | |
| ENSVATH02490832 | 304 | V>I | No | 1000Genomes | |
| ENSVATH00414644 | 310 | A>G | No | 1000Genomes | |
| ENSVATH00414645 | 319 | L>M | No | 1000Genomes | |
| tmp_3_19102566_C_T | 343 | S>F | No | 1000Genomes | |
| ENSVATH00414646 | 343 | S>P | No | 1000Genomes | |
| ENSVATH02490835 | 372 | D>N | No | 1000Genomes | |
| ENSVATH00414647 | 410 | F>Y | No | 1000Genomes | |
| ENSVATH06294954 | 421 | D>E | No | 1000Genomes | |
| ENSVATH06294953 | 421 | D>N | No | 1000Genomes | |
| tmp_3_19102871_A_G | 445 | I>V | No | 1000Genomes | |
| tmp_3_19103055_T_G | 506 | F>C | No | 1000Genomes | |
| ENSVATH14419965 | 507 | G>E | No | 1000Genomes | |
| tmp_3_19103305_G_A | 557 | V>M | No | 1000Genomes | |
| tmp_3_19103405_T_C | 590 | V>A | No | 1000Genomes | |
| tmp_3_19103585_A_G | 620 | S>G | No | 1000Genomes | |
| ENSVATH06294968 | 647 | V>A | No | 1000Genomes | |
| tmp_3_19103804_T_C | 663 | L>P | No | 1000Genomes | |
| ENSVATH00414652 | 698 | I>V | No | 1000Genomes | |
| tmp_3_19103938_C_T | 708 | L>F | No | 1000Genomes | |
| tmp_3_19103972_A_G | 719 | K>R | No | 1000Genomes | |
| tmp_3_19103981_G_A | 722 | R>K | No | 1000Genomes | |
| tmp_3_19104287_C_T | 773 | A>V | No | 1000Genomes | |
| ENSVATH06294970 | 776 | V>I | No | 1000Genomes | |
| tmp_3_19104305_C_T | 779 | A>V | No | 1000Genomes | |
| ENSVATH12709814 | 849 | C>W | No | 1000Genomes | |
| tmp_3_19104533_G_C | 855 | G>A | No | 1000Genomes | |
| tmp_3_19104563_C_T | 865 | A>V | No | 1000Genomes | |
| tmp_3_19104566_G_A,T | 866 | R>H | No | 1000Genomes | |
| tmp_3_19104566_G_A,T | 866 | R>L | No | 1000Genomes | |
| tmp_3_19104571_C_T | 868 | H>Y | No | 1000Genomes | |
| tmp_3_19104599_A_G | 877 | K>R | No | 1000Genomes | |
| tmp_3_19104610_G_C | 881 | A>P | No | 1000Genomes | |
| tmp_3_19104628_A_G | 887 | R>G | No | 1000Genomes |
No associated diseases with Q84W41
No regional properties for Q84W41
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q84W41 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium channel activity | Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. |
| glutamate receptor activity | Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
| ligand-gated ion channel activity | Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. |
| signaling receptor activity | Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| calcium ion transport | The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| calcium-mediated signaling | Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions. |
| cell-cell signaling | Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. |
| cellular response to amino acid stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. |
| induced systemic resistance, jasmonic acid mediated signaling pathway | The series of molecular signals mediated by jasmonic acid involved in induced systemic resistance. |
| response to wounding | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. |
14 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O60391 | GRIN3B | Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (Human) | PR |
| Q12879 | GRIN2A | Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (Human) | PR |
| Q91ZU9 | Grin3b | Glutamate receptor ionotropic, NMDA 3B | Mus musculus (Mouse) | PR |
| P23819 | Gria2 | Glutamate receptor 2 | Mus musculus (Mouse) | PR |
| P35439 | Grin1 | Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Rat) | PR |
| P19491 | Gria2 | Glutamate receptor 2 | Rattus norvegicus (Rat) | PR |
| Q8VHN2 | Grin3b | Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Rat) | PR |
| O04660 | GLR2.1 | Glutamate receptor 2.1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O81078 | GLR2.9 | Glutamate receptor 2.9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O81776 | GLR2.4 | Glutamate receptor 2.4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9C8E7 | GLR3.3 | Glutamate receptor 3.3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SDQ4 | GLR3.7 | Glutamate receptor 3.7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SHV1 | GLR2.2 | Glutamate receptor 2.2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SHV2 | GLR2.3 | Glutamate receptor 2.3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKWFLLMLII | CNAVPLQGLT | KIVSARPQVV | NIGSVFTFNS | LIGKVIKVAM | DAAVEDVNAS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PSILNTTTLR | IIMHDTKYNG | FMSIMEPLQF | MESETVAIIG | PQRSTTARVV | AHVATELKIP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ILSFSATDPT | MSPLQFPFFI | RTSQNDLFQM | AAIADIVQFY | GWREVVAIYG | DDDYGRNGVA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ALGDRLSEKR | CRISYKAALP | PAPTRENITD | LLIKVALSES | RIIVVHASFI | WGLELFNVAR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NLGMMSTGYV | WIATNWLSTI | IDTDSPLPLD | TINNIQGVIT | LRLHTPNSIM | KQNFVQRWHN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LTHVGLSTYA | LYAYDTVWLL | AQAIDDFFKK | GGNVSFSKNP | IISELGGGNL | HLDALKVFDG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GKIFLESILQ | VDRIGLTGRM | KFTSDRNLVN | PAFDVLNVIG | TGYTTIGYWF | NHSGLSVMPA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DEMENTSFSG | QKLHSVVWPG | HSIKIPRGWV | FSNNGRHLRI | GVPNRYRFEE | VVSVKSNGMI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| TGFCVDVFIA | AINLLPYAVP | FELVAFGNGH | DNPSNSELVR | LITTGVYDAG | VGDITIITER |
| 550 | 560 | 570 | 580 | 590 | 600 |
| TKMADFTQPY | VESGLVVVAP | VRKLGSSAMA | FLRPFTPQMW | LIAAASFLIV | GAVIWCLEHK |
| 610 | 620 | 630 | 640 | 650 | 660 |
| HNDEFRGPPR | RQVITTFWFS | FSTLFFSHRE | TTTSNLGRIV | LIIWLFVVLI | INSSYTASLT |
| 670 | 680 | 690 | 700 | 710 | 720 |
| SILTVHQLSS | PIKGIETLQT | NHDPIGYPQG | SFVRDYLIHE | LNIHVSRLVP | LRSPEEYDKA |
| 730 | 740 | 750 | 760 | 770 | 780 |
| LRDGPGKGGV | AAVVDERAYI | ELFLSNRCEF | GIVGQEFTKN | GWGFAFPRNS | PLAVDVSAAI |
| 790 | 800 | 810 | 820 | 830 | 840 |
| LQLSENGDMQ | RIRDKWLLRK | ACSLQGAEIE | VDRLELKSFW | GLFVVCGVAC | VLALAVYTVL |
| 850 | 860 | 870 | 880 | 890 | 900 |
| MIRQFGQQCP | EEAEGSIRRR | SSPSARIHSF | LSFVKEKEED | AKARSSRERQ | LEDISANGSS |
| RCN |