Q6Z2X6

PR
Gene name
Os02g0139700 (LOC_Os02g04710, OJ1679_B08.9)
Protein name
Cycloartenol synthase
Names
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4328256
EC number
5.4.99.8: Transferring other groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

12-89 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6Z2X6

Entry ID Method Resolution Chain Position Source
AF-Q6Z2X6-F1 Predicted AlphaFoldDB

No variants for Q6Z2X6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6Z2X6

No associated diseases with Q6Z2X6

3 regional properties for Q6Z2X6

Type Name Position InterPro Accession
conserved_site Terpene synthase, conserved site 604 - 618 IPR002365
domain Squalene cyclase, C-terminal 414 - 752 IPR032696
domain Squalene cyclase, N-terminal 100 - 402 IPR032697

Functions

Description
EC Number 5.4.99.8 Transferring other groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
lipid droplet An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.

1 GO annotations of molecular function

Name Definition
cycloartenol synthase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol.

1 GO annotations of biological process

Name Definition
triterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units.

11 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P38604 ERG7 Lanosterol synthase ERG7 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
B6EXY6 BAS Beta-amyrin synthase Arabidopsis thaliana (Mouse-ear cress) PR
O23390 BARS1 Baruol synthase Arabidopsis thaliana (Mouse-ear cress) PR
P38605 CAS1 Cycloartenol synthase Arabidopsis thaliana (Mouse-ear cress) PR
Q1G1A4 LAS1 Lanosterol synthase Arabidopsis thaliana (Mouse-ear cress) PR
Q9FJV8 MRN1 Marneral synthase Arabidopsis thaliana (Mouse-ear cress) PR
Q9FR95 PEN1 Arabidiol synthase Arabidopsis thaliana (Mouse-ear cress) PR
Q9FZI2 LUP5 Lupeol synthase 5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LVY2 PEN3 Tirucalladienol synthase Arabidopsis thaliana (Mouse-ear cress) PR
Q9SYN1 PEN6 Seco-amyrin synthase Arabidopsis thaliana (Mouse-ear cress) PR
Q9FI37 THAS1 Thalianol synthase 1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MWRLRVAEGG GDPWLRTKNG HVGRQVWEFD PAAGDPDELA AVEAARRGFA ARRHELKHSS
70 80 90 100 110 120
DLLMRMQFAK ANPLKLDIPA IKLEEHEAVT GEAVLSSLKR AIARYSTFQA HDGHWPGDYG
130 140 150 160 170 180
GPMFLMPGLI ITLYVSGALN TALSSEHQKE IRRYLYNHQN EDGGWGLHIE GHSTMFGSAL
190 200 210 220 230 240
TYVSLRLLGE GPDSGDGAME KGRKWILDHG GATYITSWGK FWLSVLGVFD WSGNNPVPPE
250 260 270 280 290 300
IWLLPYFLPI HPGRMWCHCR MVYLPMCYIY GKRFVGPVTP IILELRKELY EVPYNEVDWD
310 320 330 340 350 360
KARNLCAKED LYYPHPFVQD VLWATLHKFV EPAMLRWPGN KLREKALDTV MQHIHYEDEN
370 380 390 400 410 420
TRYICIGPVN KVLNMLACWI EDPNSEAFKL HIPRVHDYLW IAEDGMKMQG YNGSQLWDTA
430 440 450 460 470 480
FTVQAIVATG LIEEFGPTLK LAHGYIKKTQ VIDDCPGDLS QWYRHISKGA WPFSTADHGW
490 500 510 520 530 540
PISDCTAEGL KAALLLSKIS PDIVGEAVEV NRLYDSVNCL MSYMNDNGGF ATYELTRSYA
550 560 570 580 590 600
WLELINPAET FGDIVIDYPY VECTSAAIQA LTAFKKLYPG HRKSEIDNCI SKAASFIEGI
610 620 630 640 650 660
QKSDGSWYGS WAVCFTYGTW FGVKGLVAAG RTFKNSPAIR KACDFLLSKE LPSGGWGESY
670 680 690 700 710 720
LSSQDQVYTN LEGKRPHAVN TGWAMLALID AGQAERDPIP LHRAAKVLIN LQSEDGEFPQ
730 740 750
QEIIGVFNKN CMISYSEYRN IFPIWALGEY RRRVLAADK