Q13507
PR
Gene name |
TRPC3 (TRP3) |
Protein name |
Short transient receptor potential channel 3 |
Names |
TrpC3, Transient receptor protein 3, TRP-3, hTrp-3, hTrp3 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:7222 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
9 structures for Q13507
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 5ZBG | EM | 436 A | A/B/C/D | 86-921 | PDB |
| 6CUD | EM | 330 A | A/B/C/D | 86-891 | PDB |
| 6D7L | EM | 400 A | A/B/C/D | 86-921 | PDB |
| 6DJS | EM | 580 A | A/B/C/D | 86-384 | PDB |
| 7DXB | EM | 270 A | A/B/C/D | 86-921 | PDB |
| 7DXC | EM | 306 A | A/B/C/D | 86-921 | PDB |
| 7DXD | EM | 390 A | A/B/C/D | 86-921 | PDB |
| 7DXE | EM | 320 A | A/B/C/D | 352-821 | PDB |
| AF-Q13507-F1 | Predicted | AlphaFoldDB |
562 variants for Q13507
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA200152 RCV000172856 rs142339351 |
762 | R>H | Spinocerebellar ataxia type 41 [ClinVar] | Yes |
ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD |
|
VAR_073835 CA3064721 rs754235477 |
847 | R>H | SCA41; toxic gain of function effect [UniProt] | Yes |
ClinGen UniProt ExAC dbSNP gnomAD |
|
CA358053939 rs1193319891 |
2 | S>Y | No |
ClinGen TOPMed |
|
|
rs201517101 CA3065217 |
5 | V>D | No |
ClinGen ExAC gnomAD |
|
|
CA104755863 rs967558840 |
8 | C>G | No |
ClinGen TOPMed gnomAD |
|
|
CA3065216 rs754481922 |
9 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA104755855 rs894473465 |
10 | E>K | No |
ClinGen Ensembl |
|
|
CA358053680 rs1578668270 |
14 | V>G | No |
ClinGen Ensembl |
|
|
CA358053687 rs1288753027 |
14 | V>L | No |
ClinGen gnomAD |
|
|
CA104755835 rs372659964 |
15 | T>I | No |
ClinGen Ensembl |
|
|
rs1020449110 CA104755828 |
16 | F>L | No |
ClinGen TOPMed |
|
|
CA358053660 rs1020449110 |
16 | F>V | No |
ClinGen TOPMed |
|
|
CA358053626 rs1347257491 |
17 | P>L | No |
ClinGen gnomAD |
|
|
rs1461310602 CA358053590 |
19 | P>L | No |
ClinGen gnomAD |
|
| TCGA novel | 25 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358053465 rs1162411152 |
25 | E>Q | No |
ClinGen gnomAD |
|
|
CA104755817 rs1038325928 |
26 | G>D | No |
ClinGen TOPMed gnomAD |
|
|
CA358053444 rs1164099126 |
26 | G>S | No |
ClinGen TOPMed |
|
|
CA358053432 rs1185812030 |
27 | E>K | No |
ClinGen gnomAD |
|
|
rs1228951713 CA358053393 |
28 | D>E | No |
ClinGen Ensembl |
|
|
CA358053398 rs1351339343 |
28 | D>G | No |
ClinGen gnomAD |
|
|
CA358053382 rs1243567014 |
29 | E>* | No |
ClinGen TOPMed gnomAD |
|
|
CA358053387 rs1243567014 |
29 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
rs1333970724 CA358053327 |
31 | A>V | No |
ClinGen gnomAD |
|
|
CA104755798 rs893389282 |
33 | P>R | No |
ClinGen TOPMed |
|
|
CA358053297 rs1271468810 |
33 | P>S | No |
ClinGen gnomAD |
|
|
rs1322350979 CA358053286 |
34 | Q>* | No |
ClinGen gnomAD |
|
|
rs1294956708 CA358053275 |
34 | Q>R | No |
ClinGen gnomAD |
|
|
CA358053261 rs1213255785 |
35 | R>C | No |
ClinGen gnomAD |
|
|
CA358053254 rs1364690878 |
35 | R>H | No |
ClinGen gnomAD |
|
|
rs1364690878 CA358053248 |
35 | R>L | No |
ClinGen gnomAD |
|
|
rs1213255785 CA358053258 |
35 | R>S | No |
ClinGen gnomAD |
|
|
rs1392792360 CA358053234 |
36 | R>H | No |
ClinGen gnomAD |
|
|
CA358053242 rs1440600621 |
36 | R>S | No |
ClinGen gnomAD |
|
|
CA358053213 rs1462714005 |
37 | R>H | No |
ClinGen gnomAD |
|
|
rs1323430188 CA358053226 |
37 | R>S | No |
ClinGen gnomAD |
|
|
rs1034566796 CA104755797 |
38 | R>W | No |
ClinGen TOPMed |
|
|
CA358053192 rs1169143600 |
39 | G>C | No |
ClinGen gnomAD |
|
|
CA358053196 rs1169143600 |
39 | G>S | No |
ClinGen gnomAD |
|
|
rs1421560760 CA358053181 |
40 | W>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA358053168 rs1189201261 |
40 | W>C | No |
ClinGen gnomAD |
|
|
rs757957105 CA3065212 |
41 | R>G | No |
ClinGen ExAC |
|
|
CA358053154 rs1467832993 |
41 | R>S | No |
ClinGen TOPMed gnomAD |
|
|
CA358053149 rs1578667947 |
42 | G>R | No |
ClinGen Ensembl |
|
|
rs754251873 CA3065211 |
43 | V>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs754251873 CA358053141 |
43 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358053139 rs754251873 |
43 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1488930870 CA358053120 |
44 | N>K | No |
ClinGen TOPMed gnomAD |
|
|
CA358053124 rs1457598190 |
44 | N>S | No |
ClinGen TOPMed |
|
|
rs1202510129 CA358053112 |
45 | G>E | No |
ClinGen gnomAD |
|
|
CA358053116 rs1005455486 |
45 | G>R | No |
ClinGen gnomAD |
|
|
rs1005455486 CA104755770 |
45 | G>W | No |
ClinGen gnomAD |
|
|
CA358053105 rs1309387876 |
46 | G>E | No |
ClinGen gnomAD |
|
|
rs867458970 CA104755760 |
46 | G>R | No |
ClinGen Ensembl |
|
|
CA358053101 rs1298950095 |
47 | L>P | No |
ClinGen gnomAD |
|
|
rs201270718 CA3065210 |
49 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs201270718 CA104755755 |
49 | P>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs201270718 CA358053088 |
49 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358053083 rs1407337993 |
50 | R>P | No |
ClinGen TOPMed |
|
|
CA104755729 rs922413316 |
51 | S>L | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 51 | S>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs756617597 CA3065209 |
52 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1283147679 CA358053066 |
53 | P>L | No |
ClinGen TOPMed |
|
|
rs1013270865 CA104755728 |
55 | Q>R | No |
ClinGen TOPMed |
|
|
rs1578667764 CA358053043 |
56 | R>P | No |
ClinGen Ensembl |
|
|
rs1275919968 CA358052988 |
60 | G>R | No |
ClinGen TOPMed |
|
|
rs1036146442 CA104755722 |
62 | C>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs1412276172 CA358052893 |
67 | S>P | No |
ClinGen gnomAD |
|
|
CA358052859 rs1479353100 |
69 | G>A | No |
ClinGen gnomAD |
|
|
rs1169085054 CA358052865 |
69 | G>R | No |
ClinGen gnomAD |
|
|
rs753142596 CA3065208 |
70 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358052826 rs1578667671 |
72 | L>V | No |
ClinGen Ensembl |
|
|
CA3065196 rs779409909 |
73 | S>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1345331690 CA358050370 |
73 | S>P | No |
ClinGen TOPMed gnomAD |
|
|
rs1167593714 CA358050354 |
74 | M>T | No |
ClinGen TOPMed |
|
|
rs202247535 CA104743517 |
74 | M>V | No |
ClinGen Ensembl |
|
|
CA3065195 rs771787491 |
75 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs201126840 CA104743510 |
80 | L>P | No |
ClinGen gnomAD |
|
|
CA358050261 rs1397224391 |
81 | R>G | No |
ClinGen TOPMed |
|
|
rs1363043214 CA358050255 |
81 | R>T | No |
ClinGen gnomAD |
|
|
CA104743509 rs1004439563 |
82 | R>L | No |
ClinGen TOPMed gnomAD |
|
|
rs199943274 CA3065194 |
83 | M>V | No |
ClinGen ExAC gnomAD |
|
|
rs1187308292 CA358050165 |
87 | R>Q | No |
ClinGen gnomAD |
|
|
rs778212103 CA3065193 |
87 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA104743486 rs147387896 |
88 | E>G | No |
ClinGen ESP |
|
|
rs753052557 CA3065191 |
89 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA104743469 rs201614591 |
90 | G>S | No |
ClinGen Ensembl |
|
|
rs781691078 CA3065190 |
91 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358050106 rs1560714409 |
92 | R>C | No |
ClinGen Ensembl |
|
|
CA104743465 rs911188079 |
94 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA3065189 rs759565634 |
96 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358050010 rs201170528 |
99 | A>D | No |
ClinGen TOPMed gnomAD |
|
|
rs201170528 CA104743455 |
99 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
rs765544552 CA3065185 |
100 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs201657874 CA3065186 |
100 | F>V | No |
ClinGen ExAC gnomAD |
|
|
rs761767396 CA3065183 |
101 | M>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 103 | N>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs199555519 CA3065182 |
103 | N>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs768762496 CA3065181 |
104 | D>A | No |
ClinGen ExAC gnomAD |
|
|
CA104743419 rs202070483 |
105 | R>C | No |
ClinGen gnomAD |
|
|
rs202070483 CA358049920 |
105 | R>G | No |
ClinGen gnomAD |
|
|
COSM1050630 CA3065180 rs200623780 |
105 | R>H | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA gnomAD |
|
CA104743395 rs1043755033 |
106 | G>S | No |
ClinGen TOPMed |
|
|
CA358049899 rs1578650196 |
107 | T>P | No |
ClinGen Ensembl |
|
|
CA3065176 rs778493911 |
107 | T>S | No |
ClinGen ExAC gnomAD |
|
|
CA104743393 rs765481480 |
108 | S>N | No |
ClinGen Ensembl |
|
|
CA358049857 rs1578650167 |
110 | T>P | No |
ClinGen Ensembl |
|
|
rs200365791 CA3065175 |
111 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA358049831 rs199670427 |
112 | E>* | No |
ClinGen ExAC gnomAD |
|
|
rs201526609 CA104743367 |
112 | E>D | No |
ClinGen Ensembl |
|
|
CA3065172 rs199670427 |
112 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA104743376 rs199670427 |
112 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA358049816 rs1456273895 |
113 | E>K | No |
ClinGen gnomAD |
|
|
rs1373843470 CA358049781 |
115 | R>G | No |
ClinGen TOPMed |
|
|
rs780198602 CA3065170 |
115 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3065171 rs780198602 |
115 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358049775 rs780198602 |
115 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1170858390 CA358049768 |
116 | F>L | No |
ClinGen TOPMed |
|
|
CA358049743 rs1388868673 |
118 | D>H | No |
ClinGen gnomAD |
|
|
CA3065168 rs750513635 |
119 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA104743344 rs867787628 |
121 | E>K | No |
ClinGen Ensembl |
|
|
CA358049666 rs1285464303 |
122 | Y>F | No |
ClinGen gnomAD |
|
|
rs760674604 CA3065163 |
129 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs775346133 CA3065162 |
129 | R>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA104743322 rs201998131 |
131 | M>I | No |
ClinGen Ensembl |
|
|
CA104743325 rs201180906 |
131 | M>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1235577361 CA358049491 |
133 | E>Q | No |
ClinGen TOPMed |
|
|
CA104743320 rs200343434 |
135 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3065160 rs200343434 |
135 | S>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358049442 rs1560714115 |
136 | K>R | No |
ClinGen Ensembl |
|
|
rs906903027 CA104743314 |
137 | T>K | No |
ClinGen TOPMed |
|
|
rs906903027 CA104743308 |
137 | T>R | No |
ClinGen TOPMed |
|
|
CA358049388 rs1196006080 |
139 | N>K | No |
ClinGen gnomAD |
|
|
CA3065158 rs770588520 |
140 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1466863084 CA358049306 |
143 | V>A | No |
ClinGen gnomAD |
|
| TCGA novel | 143 | V>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs776988235 CA3065156 |
143 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA104743270 rs202016445 |
145 | Y>C | No |
ClinGen Ensembl |
|
|
CA104743266 rs202016445 |
145 | Y>F | No |
ClinGen Ensembl |
|
|
CA358049224 rs1424281879 |
146 | M>I | No |
ClinGen gnomAD |
|
|
rs980565857 CA104743261 |
147 | G>S | No |
ClinGen Ensembl |
|
|
rs756522573 CA3065154 |
148 | Q>LVAW* | No |
ClinGen ExAC |
|
|
CA358049181 rs1192005447 |
148 | Q>R | No |
ClinGen TOPMed |
|
|
rs1394514354 CA358049160 |
149 | N>S | No |
ClinGen TOPMed |
|
|
CA358049128 rs1191558213 |
151 | L>R | No |
ClinGen gnomAD |
|
| TCGA novel | 152 | Q>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs780494307 CA3065151 |
152 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA358049108 rs1174118621 |
154 | A>T | No |
ClinGen TOPMed |
|
|
CA3065150 rs556027008 |
156 | G>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs202076881 CA104743225 |
156 | G>S | No |
ClinGen Ensembl |
|
|
CA104743218 rs865944849 |
158 | E>K | No |
ClinGen Ensembl |
|
|
rs1240306939 CA358049021 |
160 | L>V | No |
ClinGen gnomAD |
|
|
CA104743217 rs908009388 |
161 | E>G | No |
ClinGen Ensembl |
|
|
rs1351817967 CA358048966 |
164 | E>A | No |
ClinGen gnomAD |
|
|
CA3065145 rs201636398 |
164 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3065146 rs201636398 |
164 | E>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1038618411 CA104743191 |
167 | L>F | No |
ClinGen TOPMed |
|
|
CA358048926 rs1394457759 |
168 | K>Q | No |
ClinGen gnomAD |
|
|
CA358048879 rs1394789483 |
170 | E>D | No |
ClinGen gnomAD |
|
| TCGA novel | 172 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA104743172 rs141601839 |
173 | A>E | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA358048849 rs141601839 |
173 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP NCI-TCGA TOPMed gnomAD |
|
CA358048845 COSM242066 rs1199183351 COSM1594231 |
174 | R>C | Variant assessed as Somatic; 0.0 impact. large_intestine endometrium prostate haematopoietic_and_lymphoid_tissue [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
COSM4155124 CA358048844 rs1436671176 COSM4155123 |
174 | R>H | kidney Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA358048837 rs1305074971 |
175 | I>T | No |
ClinGen TOPMed |
|
|
CA358048840 rs1270307623 |
175 | I>V | No |
ClinGen gnomAD |
|
|
rs200580955 CA3065138 CA358048822 |
177 | D>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA358048774 rs1211984456 |
182 | A>T | No |
ClinGen TOPMed |
|
|
rs1360437413 CA358048741 |
184 | S>N | No |
ClinGen TOPMed gnomAD |
|
|
CA3065132 rs772478792 |
186 | G>A | No |
ClinGen ExAC gnomAD |
|
|
rs779146736 CA3065130 |
191 | V>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 192 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 193 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1375366824 CA358048501 |
196 | N>K | No |
ClinGen gnomAD |
|
|
rs375570247 CA3065127 |
197 | H>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA gnomAD |
|
rs1416495965 CA358048427 |
201 | A>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1270164028 COSM1426656 CA358048420 |
201 | A>V | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA104743115 rs933977851 |
202 | A>V | No |
ClinGen TOPMed |
|
|
CA3065125 rs752452853 |
203 | S>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 205 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358048352 rs1469309386 |
205 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1249244286 CA358048301 |
209 | S>R | No |
ClinGen gnomAD |
|
|
COSM1694940 rs1183714568 COSM1694941 CA358048294 |
210 | P>L | skin [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA358048290 rs1483121694 |
211 | C>Y | No |
ClinGen gnomAD |
|
|
CA358048273 rs1256694861 |
213 | Q>* | No |
ClinGen gnomAD |
|
|
rs199563970 CA104743111 |
213 | Q>R | No |
ClinGen Ensembl |
|
|
CA358048258 rs1208669863 |
214 | E>Q | No |
ClinGen gnomAD |
|
|
CA3065122 rs751444947 |
218 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs1348793380 CA358048188 |
218 | D>N | No |
ClinGen gnomAD |
|
|
rs1348793380 CA358048184 |
218 | D>Y | No |
ClinGen gnomAD |
|
|
COSM3781916 rs868073711 CA104743082 COSM3781917 |
219 | D>N | pancreas Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated Ensembl NCI-TCGA |
|
rs144728749 CA358048121 |
221 | Y>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA3065119 rs749905737 |
222 | A>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA358048073 rs1322129192 |
225 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
rs1399391147 CA358048044 |
226 | D>E | No |
ClinGen gnomAD |
|
|
rs761478541 CA3065117 |
226 | D>Y | No |
ClinGen ExAC gnomAD |
|
|
CA3065116 rs199593201 |
228 | T>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs199593201 CA104743046 |
228 | T>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs199593201 CA358048023 |
228 | T>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 231 | S>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1578649289 CA358047931 |
235 | T>I | No |
ClinGen Ensembl |
|
|
CA104743013 rs967375203 |
236 | P>R | No |
ClinGen TOPMed |
|
|
CA3065111 rs749425539 |
237 | I>M | No |
ClinGen ExAC gnomAD |
|
|
rs201189354 CA104742995 |
237 | I>V | No |
ClinGen 1000Genomes |
|
|
rs369264817 CA3065110 |
240 | A>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 241 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs202181300 CA104742952 |
244 | Q>P | No |
ClinGen Ensembl |
|
|
CA358047801 rs1215815028 |
245 | K>R | No |
ClinGen TOPMed |
|
|
rs1270222783 CA358047780 |
246 | Y>* | No |
ClinGen gnomAD |
|
|
rs868163943 COSM1594233 COSM1050624 CA104742951 |
247 | E>K | Variant assessed as Somatic; impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated Ensembl NCI-TCGA |
|
rs1229265035 CA358047740 |
249 | V>G | No |
ClinGen gnomAD |
|
| TCGA novel | 251 | M>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358047672 TCGA novel rs1480352014 |
254 | M>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen TOPMed |
|
rs748331473 CA3065108 |
256 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA358047633 rs1291513421 |
257 | A>V | No |
ClinGen gnomAD |
|
|
rs1230466163 CA358047628 |
258 | R>K | No |
ClinGen gnomAD |
|
|
CA358047624 rs1380530240 |
259 | I>V | No |
ClinGen gnomAD |
|
|
rs780866260 CA3065107 |
260 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 260 | E>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs754864506 CA3065106 |
261 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1485639 rs754864506 CA358047609 |
261 | R>Q | Variant assessed as Somatic; impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
COSM1426653 rs571866879 CA3065105 |
262 | P>L | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs1185488345 CA358047595 |
263 | H>Q | No |
ClinGen TOPMed |
|
|
CA358047598 rs1473572236 |
263 | H>R | No |
ClinGen TOPMed |
|
|
CA104742921 rs200424777 |
265 | Y>C | No |
ClinGen TOPMed gnomAD |
|
|
rs780010346 CA3065104 |
267 | C>F | No |
ClinGen ExAC gnomAD |
|
|
rs1162075321 CA358047546 |
270 | G>E | No |
ClinGen gnomAD |
|
|
CA3065102 rs749960852 |
270 | G>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 270 | G>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358047543 rs1414401332 |
271 | D>Y | No |
ClinGen gnomAD |
|
|
CA3065101 rs201346610 |
273 | M>L | No |
ClinGen ExAC gnomAD |
|
|
rs200018915 CA3065100 |
278 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1578648987 CA358047478 |
279 | D>A | No |
ClinGen Ensembl |
|
| TCGA novel | 282 | S>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358047448 rs1352193957 |
283 | H>L | No |
ClinGen TOPMed |
|
|
rs760016985 CA3065097 |
285 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs200743584 CA104742898 |
285 | R>H | No |
ClinGen TOPMed gnomAD |
|
|
CA358046850 rs774832979 |
286 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA3065096 rs774832979 |
286 | S>W | No |
ClinGen ExAC gnomAD |
|
|
CA3065093 rs773166832 |
287 | R>K | No |
ClinGen ExAC gnomAD |
|
|
CA3065094 rs773166832 |
287 | R>T | No |
ClinGen ExAC gnomAD |
|
|
CA104742869 rs75867299 |
289 | N>D | No |
ClinGen 1000Genomes |
|
|
rs1458973762 CA358046781 |
291 | Y>C | No |
ClinGen gnomAD |
|
|
rs1291470168 CA358046787 |
291 | Y>H | No |
ClinGen gnomAD |
|
|
rs35202276 CA104742863 |
293 | G>E | No |
ClinGen Ensembl |
|
| TCGA novel | 294 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3065088 rs549112100 |
296 | S>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3065087 rs549112100 |
296 | S>N | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3065086 rs199754762 |
297 | P>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA104742848 rs868867606 |
298 | A>V | No |
ClinGen Ensembl |
|
|
rs199953665 CA3065085 |
300 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA358046721 rs1413526778 |
300 | L>P | No |
ClinGen TOPMed |
|
|
CA358046708 rs1293013073 |
302 | L>S | No |
ClinGen TOPMed |
|
|
CA358046694 rs1356538027 |
304 | S>I | No |
ClinGen TOPMed |
|
|
rs143595004 CA104742833 |
304 | S>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1250056098 CA358046692 |
305 | E>K | No |
ClinGen gnomAD |
|
|
CA3065082 rs778702047 |
306 | D>Y | No |
ClinGen ExAC gnomAD |
|
|
COSM1426650 rs756858799 CA358046673 |
307 | P>L | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA3065081 rs756858799 |
307 | P>Q | No |
ClinGen ExAC gnomAD |
|
|
rs756858799 CA358046674 |
307 | P>R | No |
ClinGen ExAC gnomAD |
|
|
CA104742774 rs200798348 |
308 | V>M | No |
ClinGen Ensembl |
|
|
rs200027824 CA104742767 |
310 | T>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ESP NCI-TCGA |
|
rs959568772 CA104742766 |
311 | A>S | No |
ClinGen TOPMed |
|
|
CA3065077 rs752000591 |
316 | N>I | No |
ClinGen ExAC gnomAD |
|
|
CA3065078 rs752000591 |
316 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA104742719 rs1034094432 |
319 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
rs766778670 CA3065076 |
320 | K>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1297116223 CA358046588 |
322 | A>T | No |
ClinGen gnomAD |
|
|
rs773830509 CA3065074 |
325 | E>D | No |
ClinGen ExAC gnomAD |
|
|
CA3065075 rs763565119 COSM420222 |
325 | E>K | Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs1416931902 CA358046539 |
328 | F>L | No |
ClinGen TOPMed |
|
|
CA3065073 rs765662860 |
329 | K>Q | No |
ClinGen ExAC gnomAD |
|
|
rs761995264 CA3065072 |
329 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA3065033 rs747660378 |
333 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs200628425 CA3065034 COSM202872 |
333 | R>W | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA358045289 rs1578641270 |
336 | S>C | No |
ClinGen Ensembl |
|
|
rs781033617 CA3065032 |
337 | M>K | No |
ClinGen ExAC gnomAD |
|
|
CA358045275 rs781033617 |
337 | M>T | No |
ClinGen ExAC gnomAD |
|
|
CA358045241 rs1560709173 |
339 | C>R | No |
ClinGen Ensembl |
|
|
CA358045097 rs1312968844 |
348 | D>N | No |
ClinGen gnomAD |
|
|
rs779107179 CA3065029 |
350 | C>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA104738313 rs201530788 |
350 | C>G | No |
ClinGen Ensembl |
|
|
CA358045043 rs1403632056 |
351 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs148910203 CA3065028 |
351 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA358044996 rs1578641187 |
356 | V>E | No |
ClinGen Ensembl |
|
|
rs1578641187 CA358044994 |
356 | V>G | No |
ClinGen Ensembl |
|
|
rs1370733528 CA358044974 |
359 | I>T | No |
ClinGen gnomAD |
|
|
rs1560709105 CA358044969 |
360 | L>P | No |
ClinGen Ensembl |
|
|
rs1164279030 CA358044956 |
361 | N>S | No |
ClinGen gnomAD |
|
|
CA358044908 rs1388924258 |
364 | L>R | No |
ClinGen gnomAD |
|
|
CA358044795 rs1190904957 |
372 | V>I | No |
ClinGen gnomAD |
|
| TCGA novel | 372 | V>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3065026 rs764572646 |
373 | H>R | No |
ClinGen ExAC gnomAD |
|
|
rs760782509 CA3065025 |
374 | R>G | No |
ClinGen ExAC gnomAD |
|
|
rs752749911 CA3065024 |
378 | S>L | No |
ClinGen ExAC gnomAD |
|
|
rs774747811 CA104738283 |
380 | S>N | No |
ClinGen Ensembl |
|
|
COSM1594237 CA3065023 COSM1050617 rs145694364 |
381 | R>C | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
COSM1582605 rs201312365 COSM1582604 CA3065022 |
381 | R>H | Variant assessed as Somatic; 0.0 impact. pancreas stomach [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA358044542 rs1210296759 |
382 | V>L | No |
ClinGen gnomAD |
|
|
rs1341350969 CA358044459 |
385 | A>V | No |
ClinGen gnomAD |
|
|
CA3065021 rs144632591 |
386 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 392 | K>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1208736612 CA358061759 |
393 | F>S | No |
ClinGen TOPMed |
|
|
CA358061625 rs376302115 |
401 | Q>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1183293247 CA358061634 |
401 | Q>P | No |
ClinGen gnomAD |
|
|
CA358061582 rs1176767907 |
403 | L>P | No |
ClinGen gnomAD |
|
|
rs140772812 CA3064997 |
405 | T>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3064996 rs140772812 |
405 | T>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs779641419 CA3064992 |
410 | N>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771732228 CA3064991 |
413 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs771732228 CA358061413 |
413 | G>S | No |
ClinGen ExAC gnomAD |
|
|
rs145495608 CA3064988 |
418 | T>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs748593492 CA3064987 |
419 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA104772048 rs199896613 |
419 | I>V | No |
ClinGen Ensembl |
|
|
rs1209826763 CA358061289 |
420 | A>P | No |
ClinGen gnomAD |
|
|
CA3064986 rs139352023 |
421 | I>V | No |
ClinGen ESP ExAC gnomAD |
|
|
rs199527931 CA3064985 |
423 | C>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs201911371 CA358061205 |
425 | V>F | No |
ClinGen ExAC gnomAD |
|
|
CA3064984 rs201911371 |
425 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs375572086 CA3064981 |
426 | V>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
TCGA novel rs758648981 CA3064982 |
426 | V>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen ExAC gnomAD |
|
rs150886370 CA3064979 |
429 | V>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs201593685 CA104771991 |
430 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes NCI-TCGA |
|
CA3064978 rs776491340 |
432 | G>A | No |
ClinGen ExAC TOPMed |
|
|
rs376542900 CA3064976 |
434 | P>L | No |
ClinGen ESP ExAC gnomAD |
|
|
CA3064975 rs150143801 |
438 | I>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 439 | G>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3064973 rs745455716 |
441 | W>* | No |
ClinGen ExAC |
|
|
rs568641078 CA3064972 |
442 | I>N | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs748505584 CA358061011 |
443 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs748505584 CA3064970 |
443 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs183645103 CA3064969 |
443 | A>V | No |
ClinGen 1000Genomes ESP ExAC gnomAD |
|
|
CA104771927 rs199650762 |
444 | P>S | No |
ClinGen gnomAD |
|
|
rs1578626252 CA358059986 |
450 | K>R | No |
ClinGen Ensembl |
|
| TCGA novel | 452 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1382442696 CA358059957 |
453 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
COSM1594239 CA104770302 rs931680572 COSM1050615 |
453 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
CA3064955 rs774053138 |
457 | M>T | No |
ClinGen ExAC |
|
|
rs759030673 CA3064956 |
457 | M>V | No |
ClinGen ExAC gnomAD |
|
|
CA3064954 rs770537554 |
458 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 459 | F>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358059866 rs1578626182 |
459 | F>S | No |
ClinGen Ensembl |
|
|
CA3064951 rs769078346 |
462 | H>R | No |
ClinGen ExAC gnomAD |
|
|
CA104770262 rs923158266 |
463 | A>E | No |
ClinGen TOPMed gnomAD |
|
|
CA358059814 rs1423410125 |
464 | A>G | No |
ClinGen gnomAD |
|
|
CA3064948 rs772337585 |
467 | I>M | No |
ClinGen ExAC gnomAD |
|
|
CA358059782 rs1364945637 |
467 | I>T | No |
ClinGen TOPMed |
|
|
rs146171474 CA3064949 |
467 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3064947 rs745940383 |
468 | I>N | No |
ClinGen ExAC gnomAD |
|
|
rs1252270423 CA358059741 |
471 | G>D | No |
ClinGen gnomAD |
|
|
rs1388141716 CA358059704 |
474 | V>M | No |
ClinGen gnomAD |
|
|
rs777557043 CA3064943 |
478 | S>L | No |
ClinGen ExAC gnomAD |
|
|
CA358059587 rs1224791989 |
479 | D>N | No |
ClinGen gnomAD |
|
| TCGA novel | 480 | R>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs767435026 CA3064940 |
482 | E>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1237960 rs752733418 CA3064941 COSM3428100 |
482 | E>K | thyroid Variant assessed as Somatic; 0.0 impact. large_intestine [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA104770218 rs933932660 |
483 | G>D | No |
ClinGen TOPMed |
|
|
rs933932660 CA358059510 |
483 | G>V | No |
ClinGen TOPMed |
|
|
rs766044392 CA3064937 |
486 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1305226802 CA358059445 |
486 | T>S | No |
ClinGen TOPMed |
|
|
rs769010763 CA3064934 |
489 | N>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1411336402 CA358059394 |
489 | N>S | No |
ClinGen gnomAD |
|
|
rs1336286824 CA358059376 |
490 | I>M | No |
ClinGen TOPMed |
|
|
rs760934358 CA3064933 |
491 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3064930 rs745995701 |
495 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs772677438 CA3064931 |
495 | Y>H | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 497 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1253829609 CA358059204 |
499 | I>F | No |
ClinGen gnomAD |
|
|
rs1253829609 CA358059206 |
499 | I>V | No |
ClinGen gnomAD |
|
|
COSM585556 rs1246221194 COSM1650206 CA358059160 |
501 | R>S | lung [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
rs777844665 CA3064926 |
502 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs749467554 CA3064927 |
502 | V>L | No |
ClinGen ExAC gnomAD |
|
|
rs749467554 CA358059154 |
502 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs138552308 CA104770175 |
506 | Q>* | No |
ClinGen ESP TOPMed |
|
|
rs138552308 CA358059078 |
506 | Q>E | No |
ClinGen ESP TOPMed |
|
|
rs1270125356 CA358058935 |
512 | M>T | No |
ClinGen gnomAD |
|
|
rs1307681591 CA358058873 |
515 | M>I | No |
ClinGen TOPMed gnomAD |
|
|
rs755999200 CA3064924 |
516 | V>F | No |
ClinGen ExAC gnomAD |
|
|
rs749871485 CA3064900 |
523 | W>* | No |
ClinGen ExAC gnomAD |
|
|
CA104769315 rs1041057448 |
527 | K>R | No |
ClinGen TOPMed |
|
|
rs1449297442 CA358058397 |
528 | E>D | No |
ClinGen gnomAD |
|
|
rs770463866 CA104769308 |
528 | E>V | No |
ClinGen Ensembl |
|
|
CA358058395 rs1246981889 |
529 | L>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA104769305 rs201925223 |
530 | W>C | No |
ClinGen Ensembl |
|
| TCGA novel | 531 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 532 | E>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1205751080 CA358058280 |
537 | Y>S | No |
ClinGen TOPMed |
|
|
rs756813075 CA3064898 |
538 | I>S | No |
ClinGen ExAC gnomAD |
|
|
CA358058208 rs1354165197 |
542 | W>R | No |
ClinGen gnomAD |
|
|
rs759965786 CA3064895 |
547 | F>I | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 547 | F>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1197181033 CA358058070 |
548 | G>A | No |
ClinGen TOPMed |
|
|
rs1341223949 CA358058057 |
549 | M>L | No |
ClinGen gnomAD |
|
|
rs369872151 CA104769278 |
560 | R>* | No |
ClinGen ESP TOPMed |
|
|
rs766761103 CA3064893 |
560 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358057850 rs766761103 |
560 | R>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3064892 rs763139089 |
561 | F>S | No |
ClinGen ExAC gnomAD |
|
|
rs1452563441 CA358057833 |
561 | F>V | No |
ClinGen TOPMed |
|
|
rs773114006 CA3064891 COSM1050612 COSM1594242 |
568 | T>M | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA104769266 rs34507256 |
569 | K>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs138022780 CA3064888 |
571 | Q>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs138022780 CA358057573 |
571 | Q>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs768500830 CA3064887 |
572 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
CA3064885 rs780080062 |
576 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs199633821 CA3064882 |
578 | V>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs199633821 CA3064883 |
578 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 579 | Q>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1270896965 CA358057314 |
580 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
CA3064881 rs756946767 |
580 | E>G | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 581 | S>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs753602268 CA3064880 |
581 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs868507778 CA104769231 |
585 | E>K | No |
ClinGen Ensembl |
|
| TCGA novel | 591 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3064878 rs201026202 |
591 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358056989 rs200366233 |
593 | Q>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3064877 rs200366233 |
593 | Q>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs766929139 CA3064876 |
596 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs1274537269 CA358056926 |
597 | Y>F | No |
ClinGen gnomAD |
|
|
CA3064858 rs751981744 |
610 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs750951273 CA3064855 |
617 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs765770767 CA3064854 |
623 | F>S | No |
ClinGen ExAC gnomAD |
|
|
CA3064853 rs761921081 |
625 | R>W | No |
ClinGen ExAC gnomAD |
|
|
CA358055626 COSM1050610 COSM1594244 rs1257675194 |
627 | A>T | Variant assessed as Somatic; impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs200357045 CA3064851 |
629 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs760849828 CA3064850 |
630 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA104767961 rs202011680 |
631 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs891551044 CA104767955 |
632 | A>S | No |
ClinGen Ensembl |
|
| TCGA novel | 634 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs375144966 CA3064849 |
636 | F>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA104767944 rs55712749 |
640 | Q>H | No |
ClinGen TOPMed |
|
|
CA3064846 rs774191611 |
644 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1341374790 CA358055286 |
645 | R>M | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 647 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358055232 rs1298348459 |
648 | K>R | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 649 | D>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1337035284 CA358055166 |
651 | F>S | No |
ClinGen gnomAD |
|
| TCGA novel | 656 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs199896927 CA104767921 |
659 | M>T | No |
ClinGen gnomAD |
|
|
rs1229153649 CA358054864 |
666 | I>V | No |
ClinGen Ensembl |
|
|
rs748829521 CA3064844 |
670 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs1401204740 CA358054712 |
673 | S>A | No |
ClinGen gnomAD |
|
|
rs1465658748 CA358054672 |
674 | Y>* | No |
ClinGen TOPMed |
|
|
rs777376339 CA358054658 |
675 | Y>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358054633 rs1446275099 |
678 | A>T | No |
ClinGen gnomAD |
|
|
CA3064841 rs747700292 |
678 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA3064840 rs780885360 |
683 | A>V | No |
ClinGen ExAC |
|
|
CA358054466 rs1404878170 |
685 | T>I | No |
ClinGen gnomAD |
|
|
CA3064826 rs772859650 |
691 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs762915832 CA3064827 |
691 | F>Y | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 692 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 693 | T>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1267321724 CA358054123 |
694 | L>I | No |
ClinGen gnomAD |
|
| TCGA novel | 701 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3064825 rs769488090 |
705 | T>S | No |
ClinGen ExAC gnomAD |
|
|
rs200581023 CA104766175 COSM215926 |
707 | V>I | central_nervous_system [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs200581023 CA358054033 |
707 | V>L | No |
ClinGen gnomAD |
|
|
CA104766146 rs199543039 |
710 | K>N | No |
ClinGen Ensembl |
|
|
rs1297339645 CA358054013 |
710 | K>R | No |
ClinGen gnomAD |
|
| TCGA novel | 712 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 714 | K>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1288145887 CA358053924 |
715 | F>Y | No |
ClinGen TOPMed |
|
|
CA358053864 rs1214599634 |
718 | N>S | No |
ClinGen gnomAD |
|
|
rs779213035 CA3064820 |
720 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA3064819 rs148274998 |
721 | Y>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3064817 COSM1594247 COSM1050604 rs146271874 |
722 | V>I | endometrium [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
CA104766103 rs199605661 |
723 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
| TCGA novel | 726 | I>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3064815 rs752796351 |
728 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1560695591 CA358053671 |
729 | V>I | No |
ClinGen Ensembl |
|
|
rs371143303 CA3064813 |
730 | T>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3064812 rs751403539 |
730 | T>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 730 | T>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs762830463 CA3064810 |
733 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs201237198 CA104766077 |
734 | V>I | No |
ClinGen Ensembl |
|
| TCGA novel | 736 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA104766070 rs200144774 |
738 | M>I | No |
ClinGen 1000Genomes |
|
| TCGA novel | 738 | M>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 741 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA358053381 rs1481047740 |
743 | I>L | No |
ClinGen gnomAD |
|
|
rs768849197 CA3064775 |
752 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs747055538 CA3064774 |
755 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs1461323686 CA358052976 |
756 | V>A | No |
ClinGen gnomAD |
|
|
rs1286787693 CA358052982 |
756 | V>I | No |
ClinGen gnomAD |
|
|
CA3064772 rs200628918 |
762 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA3064771 COSM4150441 COSM4150440 rs778706772 |
763 | S>* | ovary [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA3064770 rs757158418 |
768 | S>Y | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 769 | Y>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3064768 rs763905038 |
771 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs897321679 CA104765097 |
772 | D>E | No |
ClinGen Ensembl |
|
|
CA3064767 rs760224432 |
772 | D>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1273666621 CA358052767 |
774 | K>N | No |
ClinGen TOPMed |
|
|
CA104765088 rs1041200934 |
776 | L>F | No |
ClinGen Ensembl |
|
|
CA3064766 rs752150959 |
777 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3064765 rs767183859 |
780 | F>L | No |
ClinGen ExAC gnomAD |
|
|
COSM76833 CA358052712 rs1386284134 |
783 | V>A | ovary large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs1423085434 CA358052705 |
784 | P>L | No |
ClinGen gnomAD |
|
|
CA104765046 rs201837224 |
785 | S>N | No |
ClinGen TOPMed |
|
|
CA3064763 rs773461977 |
788 | S>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA104764999 rs377595572 |
789 | F>L | No |
ClinGen ESP TOPMed |
|
|
rs751869472 CA104765004 |
789 | F>Y | No |
ClinGen Ensembl |
|
|
CA3064761 rs145430158 |
793 | I>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA104764996 rs145430158 |
793 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA358052641 rs1372186923 |
794 | M>T | No |
ClinGen gnomAD |
|
|
rs777236974 COSM3008477 COSM1050600 CA3064760 |
795 | R>* | endometrium [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs201449154 CA3064758 |
795 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs201449154 CA3064759 |
795 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
COSM1594251 rs201449154 CA3064757 COSM1050599 |
795 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA104764909 rs1031627987 |
796 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
rs200645413 CA104764903 |
798 | N>D | No |
ClinGen TOPMed gnomAD |
|
|
CA358052598 rs1293654067 |
801 | K>R | No |
ClinGen gnomAD |
|
|
rs1472888531 CA358052564 |
806 | R>G | No |
ClinGen gnomAD |
|
|
CA358052560 rs11732666 |
806 | R>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1268686281 CA358052556 |
807 | L>F | No |
ClinGen gnomAD |
|
|
CA358052531 rs1229640179 |
810 | D>G | No |
ClinGen gnomAD |
|
|
rs1368081260 CA358052523 |
811 | I>M | No |
ClinGen gnomAD |
|
|
CA3064752 rs757145687 |
811 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA358052527 rs1283127579 |
811 | I>V | No |
ClinGen gnomAD |
|
|
CA3064751 rs749012888 |
812 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358052522 rs749012888 |
812 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3064750 rs35312610 |
813 | M>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3064749 rs200465648 |
816 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3064747 rs377662018 |
820 | S>F | No |
ClinGen ESP ExAC gnomAD |
|
|
CA3064746 rs754469967 |
821 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA3064730 rs777360921 |
823 | N>T | No |
ClinGen ExAC gnomAD |
|
|
CA358051611 rs1242816665 |
827 | Q>* | No |
ClinGen gnomAD |
|
|
rs1351724863 CA358051503 |
836 | H>D | No |
ClinGen TOPMed |
|
|
CA358051477 rs1223730850 |
838 | F>L | No |
ClinGen gnomAD |
|
|
rs754521633 CA3064725 |
839 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs1281638595 CA358051444 |
840 | S>N | No |
ClinGen gnomAD |
|
| TCGA novel | 840 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3064724 rs751012220 |
843 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs766080390 CA3064723 |
844 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
CA104762423 rs1030471090 |
846 | T>I | No |
ClinGen TOPMed |
|
|
rs138232580 CA3064722 |
847 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs764499384 CA3064720 |
848 | Y>* | No |
ClinGen ExAC gnomAD |
|
|
rs576172174 CA3064719 |
849 | Q>K | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA358049668 rs1217994757 |
851 | I>L | No |
ClinGen gnomAD |
|
|
CA3064696 rs759890523 |
856 | I>T | No |
ClinGen ExAC |
|
| TCGA novel | 858 | R>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA104748714 rs953488230 |
859 | Y>C | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 859 | Y>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3064695 rs751669005 |
869 | N>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1553936310 RCV000585627 CA358049208 |
874 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ClinVar Ensembl NCI-TCGA dbSNP |
|
CA104746533 rs767196076 |
877 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA358048208 rs1265598395 |
880 | I>V | No |
ClinGen gnomAD |
|
|
rs781639411 CA3064679 |
883 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA358048097 rs1322708540 |
889 | Y>F | No |
ClinGen gnomAD |
|
|
rs200301137 CA104746475 |
894 | D>N | No |
ClinGen Ensembl |
|
|
RCV000960141 CA3064674 rs142202711 |
896 | S>G | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs765477300 CA3064673 |
897 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA358047982 rs1344876736 |
897 | Q>R | No |
ClinGen gnomAD |
|
|
rs1440271038 CA358047962 |
899 | T>P | No |
ClinGen gnomAD |
|
|
rs201127695 CA3064671 |
900 | E>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3064670 rs200028855 |
901 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA358047921 rs1578589945 |
902 | L>I | No |
ClinGen Ensembl |
|
|
CA358047905 rs1436547401 |
903 | A>V | No |
ClinGen gnomAD |
|
| TCGA novel | 905 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs369424795 CA358047828 |
909 | L>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs369424795 CA3064666 |
909 | L>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs375175884 CA104746380 |
910 | S>G | No |
ClinGen ESP TOPMed |
|
|
CA3064665 rs145948370 |
912 | K>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA3064664 rs199588234 |
915 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
1 associated diseases with Q13507
[MIM: 616410]: Spinocerebellar ataxia 41 (SCA41)
A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. {ECO:0000269|PubMed:25477146}. Note=The disease is caused by variants affecting the gene represented in this entry.
Without disease ID
- A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. {ECO:0000269|PubMed:25477146}. Note=The disease is caused by variants affecting the gene represented in this entry.
4 regional properties for Q13507
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Ankyrin repeat | 111 - 199 | IPR002110-1 |
| repeat | Ankyrin repeat | 232 - 261 | IPR002110-2 |
| domain | Ion transport domain | 489 - 754 | IPR005821 |
| domain | Transient receptor ion channel domain | 267 - 329 | IPR013555 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cation channel complex | An ion channel complex through which cations pass. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium channel activity | Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. |
| inositol 1,4,5 trisphosphate binding | Binding to inositol 1,4,5 trisphosphate. |
| store-operated calcium channel activity | A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores. |
10 GO annotations of biological process
| Name | Definition |
|---|---|
| calcium ion transmembrane transport | A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. |
| calcium ion transport | The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| manganese ion transport | The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| phototransduction | The sequence of reactions within a cell required to convert absorbed photons into a molecular signal. |
| positive regulation of calcium ion transport into cytosol | Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components. |
| positive regulation of cardiac muscle hypertrophy in response to stress | Any process that activates or increases the frequency, rate or extent of cardiac muscle hypertrophy in response to stress. |
| regulation of cytosolic calcium ion concentration | Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings. |
| response to ATP | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus. |
| response to calcium ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. |
| single fertilization | The union of male and female gametes to form a zygote. |
20 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O18784 | TRPC1 | Short transient receptor potential channel 1 | Bos taurus (Bovine) | PR |
| P79100 | TRPC4 | Short transient receptor potential channel 4 | Bos taurus (Bovine) | PR |
| P19334 | trp | Transient receptor potential protein | Drosophila melanogaster (Fruit fly) | PR |
| P48994 | trpl | Transient-receptor-potential-like protein | Drosophila melanogaster (Fruit fly) | PR |
| Q9HCX4 | TRPC7 | Short transient receptor potential channel 7 | Homo sapiens (Human) | PR |
| Q9Y210 | TRPC6 | Short transient receptor potential channel 6 | Homo sapiens (Human) | PR |
| P48995 | TRPC1 | Short transient receptor potential channel 1 | Homo sapiens (Human) | PR |
| Q9UL62 | TRPC5 | Short transient receptor potential channel 5 | Homo sapiens (Human) | PR |
| Q9UBN4 | TRPC4 | Short transient receptor potential channel 4 | Homo sapiens (Human) | PR |
| Q9WVC5 | Trpc7 | Short transient receptor potential channel 7 | Mus musculus (Mouse) | PR |
| Q9QUQ5 | Trpc4 | Short transient receptor potential channel 4 | Mus musculus (Mouse) | PR |
| Q9QX29 | Trpc5 | Short transient receptor potential channel 5 | Mus musculus (Mouse) | PR |
| Q61143 | Trpc6 | Short transient receptor potential channel 6 | Mus musculus (Mouse) | PR |
| Q9R244 | Trpc2 | Short transient receptor potential channel 2 | Mus musculus (Mouse) | PR |
| Q61056 | Trpc1 | Short transient receptor potential channel 1 | Mus musculus (Mouse) | PR |
| Q9QZC1 | Trpc3 | Short transient receptor potential channel 3 | Mus musculus (Mouse) | PR |
| Q9QX01 | Trpc1 | Short transient receptor potential channel 1 | Rattus norvegicus (Rat) | PR |
| O35119 | Trpc4 | Short transient receptor potential channel 4 | Rattus norvegicus (Rat) | PR |
| Q9R283 | Trpc2 | Short transient receptor potential channel 2 | Rattus norvegicus (Rat) | PR |
| Q9JMI9 | Trpc3 | Short transient receptor potential channel 3 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSTKVRKCKE | QARVTFPAPE | EEEDEGEDEG | AEPQRRRRGW | RGVNGGLEPR | SAPSQREPHG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YCPPPFSHGP | DLSMEGSPSL | RRMTVMREKG | RRQAVRGPAF | MFNDRGTSLT | AEEERFLDAA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EYGNIPVVRK | MLEESKTLNV | NCVDYMGQNA | LQLAVGNEHL | EVTELLLKKE | NLARIGDALL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LAISKGYVRI | VEAILNHPGF | AASKRLTLSP | CEQELQDDDF | YAYDEDGTRF | SPDITPIILA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AHCQKYEVVH | MLLMKGARIE | RPHDYFCKCG | DCMEKQRHDS | FSHSRSRINA | YKGLASPAYL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SLSSEDPVLT | ALELSNELAK | LANIEKEFKN | DYRKLSMQCK | DFVVGVLDLC | RDSEEVEAIL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NGDLESAEPL | EVHRHKASLS | RVKLAIKYEV | KKFVAHPNCQ | QQLLTIWYEN | LSGLREQTIA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IKCLVVLVVA | LGLPFLAIGY | WIAPCSRLGK | ILRSPFMKFV | AHAASFIIFL | GLLVFNASDR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| FEGITTLPNI | TVTDYPKQIF | RVKTTQFTWT | EMLIMVWVLG | MMWSECKELW | LEGPREYILQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LWNVLDFGML | SIFIAAFTAR | FLAFLQATKA | QQYVDSYVQE | SDLSEVTLPP | EIQYFTYARD |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KWLPSDPQII | SEGLYAIAVV | LSFSRIAYIL | PANESFGPLQ | ISLGRTVKDI | FKFMVLFIMV |
| 670 | 680 | 690 | 700 | 710 | 720 |
| FFAFMIGMFI | LYSYYLGAKV | NAAFTTVEES | FKTLFWSIFG | LSEVTSVVLK | YDHKFIENIG |
| 730 | 740 | 750 | 760 | 770 | 780 |
| YVLYGIYNVT | MVVVLLNMLI | AMINSSYQEI | EDDSDVEWKF | ARSKLWLSYF | DDGKTLPPPF |
| 790 | 800 | 810 | 820 | 830 | 840 |
| SLVPSPKSFV | YFIMRIVNFP | KCRRRRLQKD | IEMGMGNSKS | RLNLFTQSNS | RVFESHSFNS |
| 850 | 860 | 870 | 880 | 890 | 900 |
| ILNQPTRYQQ | IMKRLIKRYV | LKAQVDKEND | EVNEGELKEI | KQDISSLRYE | LLEDKSQATE |
| 910 | 920 | ||||
| ELAILIHKLS | EKLNPSMLRC | E |