Q05497
Gene name |
YDR338C (D9651.8) |
Protein name |
Uncharacterized transporter YDR338C |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YDR338C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q05497
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q05497-F1 | Predicted | AlphaFoldDB |
6 variants for Q05497
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s04-1149041 | 140 | S>R | No | SGRP | |
| s04-1149024 | 146 | D>G | No | SGRP | |
| s04-1148771 | 230 | R>S | No | SGRP | |
| s04-1147972 | 497 | A>T | No | SGRP | |
| s04-1147945 | 506 | I>V | No | SGRP | |
| s04-1147483 | 660 | M>L | No | SGRP |
No associated diseases with Q05497
No regional properties for Q05497
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q05497 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| antiporter activity | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out). |
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
| xenobiotic transmembrane transporter activity | Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| xenobiotic detoxification by transmembrane export across the plasma membrane | A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell. |
11 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O49660 | DTX56 | Protein DETOXIFICATION 56 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SIA5 | DTX1 | Protein DETOXIFICATION 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4HQ05 | DTX8 | Protein DETOXIFICATION 8 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9C994 | DTX14 | Protein DETOXIFICATION 14 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LPV4 | DTX31 | Protein DETOXIFICATION 31 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4I4Q3 | DTX32 | Protein DETOXIFICATION 32 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4HPH1 | DTX22 | Protein DETOXIFICATION 22 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8W488 | DTX21 | Protein DETOXIFICATION 21 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FNC1 | DTX28 | Protein DETOXIFICATION 28 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FKQ1 | DTX27 | Protein DETOXIFICATION 27 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FHB6 | DTX16 | Protein DETOXIFICATION 16 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGILSKTLS | EVHPSLRTNG | MGIGNTHRRI | SLGFLPPNKK | NPLVRKFRAR | TRNIDQRSFR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SLTDDFGSNV | HEPNPYLGNI | DEEPDLYYHD | EEDGELSRTI | SLPSRVSETP | ELSPQDVDWI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LHEHERRYSS | VCNSDNEEAS | QSNTPDRIQE | YSGRELEYDE | FMNRLQAQKQ | KLTRSAVTDA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KGTSHHRRPS | FVSVTSRGSV | PTIYQEIDEN | DSEALAELAH | SHVTFKSEAR | VLASYSFPLI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FTFLLEQIFP | MVCSLTVGHL | GKNELAAVSL | ASMTSNITLA | IFEGIATSLD | TLCPQAYGSG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RFYSVGVHLQ | RCIAFSLVIY | IPFAVMWWYS | EPLLSYIIPE | KELINLTSRF | LRVLILGAPA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YIFFENLKRF | LQAQGIFDAG | IYVLTICAPL | NVLVSYTLVW | NKYIGVGFIG | AAIAVVLNFW |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LMFFLLLFYA | LYIDGRKCWG | GFSRKAFTHW | NDLGHLAFSG | IIMLEAEELS | YELLTLFSAY |
| 490 | 500 | 510 | 520 | 530 | 540 |
| YGVSYLAAQS | AVSTMAALLY | MIPFAIGIST | STRIANFIGA | KRTDFAHISS | QVGLSFSFIA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| GFINCCILVF | GRNLIANIYS | KDPEVIKLIA | QVLPLVGIVQ | NFDSLNAVAG | SCLRGQGMQS |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LGSIVNLMAY | YLFGIPLALI | LSWFFDMKLY | GLWIGIGSAM | LLIGLVEAYY | VLFPDWDKIM |
| 670 | 680 | 690 | |||
| TYAEILKETE | DDEVDSDEYL | TDSDDPDENT | ALLGA |