Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LT45

Entry ID Method Resolution Chain Position Source
AF-Q9LT45-F1 Predicted AlphaFoldDB

19 variants for Q9LT45

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_3_7255110_A_C 32 D>A No 1000Genomes
ENSVATH05871703 37 V>L No 1000Genomes
tmp_3_7255526_T_C 38 V>A No 1000Genomes
tmp_3_7255552_C_T 47 R>C No 1000Genomes
ENSVATH05871704 50 L>F No 1000Genomes
ENSVATH13954806 60 E>K No 1000Genomes
tmp_3_7255603_A_C 64 N>H No 1000Genomes
tmp_3_7255607_A_T 65 N>I No 1000Genomes
tmp_3_7255654_G_A 81 V>I No 1000Genomes
tmp_3_7255664_C_A 84 P>H No 1000Genomes
ENSVATH05871707 131 N>T No 1000Genomes
tmp_3_7255808_C_A 132 S>Y No 1000Genomes
tmp_3_7255811_G_C 133 W>S No 1000Genomes
ENSVATH05871708 138 T>N No 1000Genomes
ENSVATH10810124 140 K>T No 1000Genomes
ENSVATH02170499 142 I>V No 1000Genomes
tmp_3_7255841_G_A 143 R>H No 1000Genomes
tmp_3_7255840_C_A 143 R>S No 1000Genomes
ENSVATH00336689 162 M>I No 1000Genomes

No associated diseases with Q9LT45

2 regional properties for Q9LT45

Type Name Position InterPro Accession
domain Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain 220 - 371 IPR006131
domain Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding 73 - 214 IPR006132

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

18 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P23769 GATA2 Endothelial transcription factor GATA-2 Homo sapiens (Human) PR
O09100 Gata2 Endothelial transcription factor GATA-2 Mus musculus (Mouse) PR
Q942A1 RR4 Two-component response regulator ORR4 Oryza sativa subsp japonica (Rice) PR
Q6H468 RR11 Two-component response regulator ORR11 Oryza sativa subsp japonica (Rice) PR
Q0PVB3 RR7 Two-component response regulator ORR7 Oryza sativa subsp japonica (Rice) PR
Q7Y0W5 EHD1 Two-component response regulator ORR30 Oryza sativa subsp japonica (Rice) PR
Q9ZWS9 ARR3 Two-component response regulator ARR3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FXD6 ARR11 Two-component response regulator ARR11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SB04 ARR5 Two-component response regulator ARR5 Arabidopsis thaliana (Mouse-ear cress) PR
O80366 ARR9 Two-component response regulator ARR9 Arabidopsis thaliana (Mouse-ear cress) PR
Q6LA43 APRR2 Two-component response regulator-like APRR2 Arabidopsis thaliana (Mouse-ear cress) PR
Q93WK5 APRR7 Two-component response regulator-like APRR7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FJ16 APRR4 Putative two-component response regulator-like APRR4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LVG4 APRR3 Two-component response regulator-like APRR3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LKL2 APRR1 Two-component response regulator-like APRR1 Arabidopsis thaliana (Mouse-ear cress) PR
O65515 GATA7 GATA transcription factor 7 Arabidopsis thaliana (Mouse-ear cress) PR
Q8L4M6 GATA3 GATA transcription factor 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SKN6 GATA13 Putative GATA transcription factor 13 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEPELDLTLK LGLPNSTVET HLTLSPPTTT TDQGTNVVDG GEVINHRRGL LGDDEVIHNE
70 80 90 100 110 120
PTRNNVEFNI RIYNYVFQQF VGAPNTLNFA PYPMPPSPAP APETPPVSDE YVLIDVPARR
130 140 150 160 170 180
ARRNNSTVMT NSWKENATPK RIRGCGGFCG GRIEGMKKCT NMNCNALNTP MWRRGPLGPK
190 200
SLCNACGIKF RKEEERKAKR NVVIVLDD