O65515
PR
Gene name |
GATA7 (At4g36240, F23E13.130) |
Protein name |
GATA transcription factor 7 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G36240 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O65515
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O65515-F1 | Predicted | AlphaFoldDB |
40 variants for O65515
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH12427746 | 10 | D>E | No | 1000Genomes | |
| ENSVATH02964798 | 14 | D>E | No | 1000Genomes | |
| tmp_4_17148168_T_G | 15 | D>A | No | 1000Genomes | |
| tmp_4_17148166_G_A | 16 | L>F | No | 1000Genomes | |
|
ENSVATH02964797 ENSVATH06834333 |
24 | T>S | No | 1000Genomes | |
| ENSVATH12427745 | 28 | S>L | No | 1000Genomes | |
| tmp_4_17148126_G_A | 29 | S>F | No | 1000Genomes | |
| ENSVATH06834332 | 30 | S>L | No | 1000Genomes | |
| ENSVATH06834331 | 34 | K>E | No | 1000Genomes | |
| tmp_4_17148099_T_A | 38 | Q>L | No | 1000Genomes | |
| ENSVATH06834330 | 41 | E>D | No | 1000Genomes | |
| ENSVATH06834329 | 43 | F>L | No | 1000Genomes | |
| ENSVATH02964795 | 43 | F>S | No | 1000Genomes | |
| ENSVATH02964796 | 43 | F>V | No | 1000Genomes | |
| ENSVATH06834327 | 52 | R>C | No | 1000Genomes | |
| tmp_4_17148055_G_A | 53 | L>F | No | 1000Genomes | |
| ENSVATH06834326 | 55 | P>Q | No | 1000Genomes | |
| ENSVATH06834325 | 56 | P>S | No | 1000Genomes | |
| tmp_4_17148038_A_T | 58 | D>E | No | 1000Genomes | |
| tmp_4_17148019_C_T | 65 | D>N | No | 1000Genomes | |
| ENSVATH00555000 | 66 | A>V | No | 1000Genomes | |
| tmp_4_17147881_A_G | 71 | L>S | No | 1000Genomes | |
| tmp_4_17147834_C_T | 87 | E>K | No | 1000Genomes | |
| ENSVATH06834314 | 92 | S>T | No | 1000Genomes | |
| ENSVATH06834311 | 105 | R>Q | No | 1000Genomes | |
| tmp_4_17147772_C_G | 107 | Q>H | No | 1000Genomes | |
| ENSVATH06834308 | 123 | R>H | No | 1000Genomes | |
| ENSVATH02964790 | 134 | L>I | No | 1000Genomes | |
| ENSVATH02964789 | 135 | S>P | No | 1000Genomes | |
| ENSVATH02964788 | 139 | A>V | No | 1000Genomes | |
| ENSVATH06834307 | 142 | K>N | No | 1000Genomes | |
| ENSVATH06834306 | 143 | K>M | No | 1000Genomes | |
| tmp_4_17147654_G_C | 147 | Q>E | No | 1000Genomes | |
| ENSVATH00554996 | 149 | V>A | No | 1000Genomes | |
| ENSVATH06834305 | 155 | G>C | No | 1000Genomes | |
| tmp_4_17147599_C_G | 165 | C>S | No | 1000Genomes | |
| ENSVATH14345251 | 175 | P>R | No | 1000Genomes | |
| ENSVATH00554993 | 214 | N>T | No | 1000Genomes | |
| ENSVATH12427647 | 219 | N>I | No | 1000Genomes | |
| ENSVATH12427645 | 234 | D>Y | No | 1000Genomes |
No associated diseases with O65515
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
| zinc ion binding | Binding to a zinc ion (Zn). |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| circadian rhythm | Any biological process in an organism that recurs with a regularity of approximately 24 hours. |
| positive regulation of DNA-templated transcription | Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
| response to light stimulus | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. |
18 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P23769 | GATA2 | Endothelial transcription factor GATA-2 | Homo sapiens (Human) | PR |
| O09100 | Gata2 | Endothelial transcription factor GATA-2 | Mus musculus (Mouse) | PR |
| Q942A1 | RR4 | Two-component response regulator ORR4 | Oryza sativa subsp japonica (Rice) | PR |
| Q6H468 | RR11 | Two-component response regulator ORR11 | Oryza sativa subsp japonica (Rice) | PR |
| Q0PVB3 | RR7 | Two-component response regulator ORR7 | Oryza sativa subsp japonica (Rice) | PR |
| Q7Y0W5 | EHD1 | Two-component response regulator ORR30 | Oryza sativa subsp japonica (Rice) | PR |
| Q9ZWS9 | ARR3 | Two-component response regulator ARR3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FXD6 | ARR11 | Two-component response regulator ARR11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SB04 | ARR5 | Two-component response regulator ARR5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O80366 | ARR9 | Two-component response regulator ARR9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q6LA43 | APRR2 | Two-component response regulator-like APRR2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q93WK5 | APRR7 | Two-component response regulator-like APRR7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FJ16 | APRR4 | Putative two-component response regulator-like APRR4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LVG4 | APRR3 | Two-component response regulator-like APRR3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LKL2 | APRR1 | Two-component response regulator-like APRR1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8L4M6 | GATA3 | GATA transcription factor 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LT45 | GATA29 | GATA transcription factor 29 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SKN6 | GATA13 | Putative GATA transcription factor 13 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MECVEAFLGD | FSVDDLLDLS | NADTSLESSS | SQRKEDEQER | EKFKSFSDQS | TRLSPPEDLL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SFPGDAPVGD | LEDLEWLSNF | VEDSFSESYI | SSDFPVNPVA | SVEVRRQCVP | VKPRSKRRRT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NGRIWSMESP | SPLLSTAVAR | RKKRGRQKVD | ASYGGVVQQQ | QLRRCCSHCG | VQKTPQWRMG |
| 190 | 200 | 210 | 220 | 230 | |
| PLGAKTLCNA | CGVRFKSGRL | LPEYRPACSP | TFTNEIHSNS | HRKVLELRLM | KVADPARV |