O80366

PR
Gene name
ARR9 (ATRR4, At3g57040, F24I3.120)
Protein name
Two-component response regulator ARR9
Names
Response reactor 4
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G57040
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-88 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O80366

Entry ID Method Resolution Chain Position Source
AF-O80366-F1 Predicted AlphaFoldDB

17 variants for O80366

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06329511 2 G>C No 1000Genomes
tmp_3_21110078_C_T 7 S>L No 1000Genomes
tmp_3_21110140_C_T 28 L>F No 1000Genomes
ENSVATH14445614 31 S>T No 1000Genomes
ENSVATH06329513 53 S>N No 1000Genomes
ENSVATH00423595 54 T>I No 1000Genomes
ENSVATH02516225 61 A>G No 1000Genomes
tmp_3_21110347_C_T 65 A>V No 1000Genomes
tmp_3_21110355_A_T 68 N>Y No 1000Genomes
tmp_3_21110749_T_C 114 V>A No 1000Genomes
ENSVATH12800116 135 R>G No 1000Genomes
tmp_3_21110954_C_T 144 P>L No 1000Genomes
tmp_3_21110999_T_A 159 I>N No 1000Genomes
tmp_3_21111014_A_T 164 K>I No 1000Genomes
tmp_3_21111023_A_T 167 N>I No 1000Genomes
tmp_3_21111063_T_G 180 D>E No 1000Genomes
ENSVATH00423598 215 E>K No 1000Genomes

No associated diseases with O80366

1 regional properties for O80366

Type Name Position InterPro Accession
domain Signal transduction response regulator, receiver domain 9 - 147 IPR001789

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
phosphorelay response regulator activity Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.

5 GO annotations of biological process

Name Definition
circadian rhythm Any biological process in an organism that recurs with a regularity of approximately 24 hours.
cytokinin-activated signaling pathway The series of molecular signals generated by the binding of a cytokinin to a receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
phosphorelay signal transduction system A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
response to cytokinin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.

18 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P23769 GATA2 Endothelial transcription factor GATA-2 Homo sapiens (Human) PR
O09100 Gata2 Endothelial transcription factor GATA-2 Mus musculus (Mouse) PR
Q942A1 RR4 Two-component response regulator ORR4 Oryza sativa subsp japonica (Rice) PR
Q6H468 RR11 Two-component response regulator ORR11 Oryza sativa subsp japonica (Rice) PR
Q0PVB3 RR7 Two-component response regulator ORR7 Oryza sativa subsp japonica (Rice) PR
Q7Y0W5 EHD1 Two-component response regulator ORR30 Oryza sativa subsp japonica (Rice) PR
Q9SKN6 GATA13 Putative GATA transcription factor 13 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LT45 GATA29 GATA transcription factor 29 Arabidopsis thaliana (Mouse-ear cress) PR
Q6LA43 APRR2 Two-component response regulator-like APRR2 Arabidopsis thaliana (Mouse-ear cress) PR
Q8L4M6 GATA3 GATA transcription factor 3 Arabidopsis thaliana (Mouse-ear cress) PR
O65515 GATA7 GATA transcription factor 7 Arabidopsis thaliana (Mouse-ear cress) PR
Q93WK5 APRR7 Two-component response regulator-like APRR7 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FJ16 APRR4 Putative two-component response regulator-like APRR4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FXD6 ARR11 Two-component response regulator ARR11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LKL2 APRR1 Two-component response regulator-like APRR1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SB04 ARR5 Two-component response regulator ARR5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZWS9 ARR3 Two-component response regulator ARR3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LVG4 APRR3 Two-component response regulator-like APRR3 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MGMAAESQFH VLAVDDSLFD RKLIERLLQK SSCQVTTVDS GSKALEFLGL RQSTDSNDPN
70 80 90 100 110 120
AFSKAPVNHQ VVEVNLIITD YCMPGMTGYD LLKKVKESSA FRDIPVVIMS SENVPARISR
130 140 150 160 170 180
CLEEGAEEFF LKPVRLADLN KLKPHMMKTK LKNQKLEEIE TTSKVENGVP TAVADPEIKD
190 200 210 220 230
STNIEIEILP LQQDLLLVQQ EEQTLSINNK RKSVEEGIST DRARPRFDGI ATAV