| angiogenesis |
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. |
| brown fat cell differentiation |
The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. |
| cell differentiation in hindbrain |
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. |
| cell fate commitment |
The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. |
| cell fate determination |
A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. |
| central nervous system neuron development |
The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. |
| cochlea development |
The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound. |
| commitment of neuronal cell to specific neuron type in forebrain |
The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain. |
| definitive hemopoiesis |
A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood. |
| embryonic placenta development |
The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. |
| eosinophil fate commitment |
The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. A eosinophil is any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. |
| GABAergic neuron differentiation |
The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron. |
| glandular epithelial cell differentiation |
The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. |
| glandular epithelial cell maturation |
The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. |
| hematopoietic progenitor cell differentiation |
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells. |
| hematopoietic stem cell homeostasis |
Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells. |
| homeostasis of number of cells within a tissue |
Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue. |
| inner ear morphogenesis |
The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively. |
| myeloid cell differentiation |
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. |
| negative regulation of brown fat cell differentiation |
Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation. |
| negative regulation of endothelial cell apoptotic process |
Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process. |
| negative regulation of fat cell differentiation |
Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation. |
| negative regulation of fat cell proliferation |
Any process that stops or decreases the rate or extent of fat cell proliferation. |
| negative regulation of gene expression |
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
| negative regulation of hematopoietic progenitor cell differentiation |
Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation. |
| negative regulation of macrophage differentiation |
Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation. |
| negative regulation of myeloid cell differentiation |
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation. |
| negative regulation of neural precursor cell proliferation |
Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation. |
| negative regulation of Notch signaling pathway |
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway. |
| negative regulation of transcription by RNA polymerase II |
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| neural precursor cell proliferation |
The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell. |
| neuroendocrine cell differentiation |
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance. |
| neuron differentiation |
The process in which a relatively unspecialized cell acquires specialized features of a neuron. |
| neuron fate commitment |
The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron. |
| neuron migration |
The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature. |
| phagocytosis |
A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. |
| pituitary gland development |
The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. |
| positive regulation of angiogenesis |
Any process that activates or increases angiogenesis. |
| positive regulation of blood vessel endothelial cell migration |
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels. |
| positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis |
Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis. |
| positive regulation of cell migration involved in sprouting angiogenesis |
Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. |
| positive regulation of cytosolic calcium ion concentration |
Any process that increases the concentration of calcium ions in the cytosol. |
| positive regulation of erythrocyte differentiation |
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation. |
| positive regulation of gene expression |
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
| positive regulation of mast cell degranulation |
Any process that activates or increases the frequency, rate or extent of mast cell degranulation. |
| positive regulation of megakaryocyte differentiation |
Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation. |
| positive regulation of miRNA transcription |
Any process that activates or increases the frequency, rate or extent of microRNA (miRNA) gene transcription. |
| positive regulation of neuron differentiation |
Any process that activates or increases the frequency, rate or extent of neuron differentiation. |
| positive regulation of phagocytosis |
Any process that activates or increases the frequency, rate or extent of phagocytosis. |
| positive regulation of phagocytosis, engulfment |
Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. |
| positive regulation of transcription by RNA polymerase II |
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
| regulation of forebrain neuron differentiation |
Any process that modulates the frequency, rate or extent of forebrain neuron differentiation. |
| regulation of histone acetylation |
Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein. |
| regulation of primitive erythrocyte differentiation |
Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis. |
| response to lipid |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. |
| semicircular canal development |
The progression of the semicircular canal from its initial formation to the mature structure. |
| somatic stem cell population maintenance |
Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. |
| thyroid-stimulating hormone-secreting cell differentiation |
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin. |
| transcription by RNA polymerase II |
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). |
| urogenital system development |
The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure. |
| vascular wound healing |
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. |
| ventral spinal cord interneuron differentiation |
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate. |
