Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

2 structures for Q9FY46

Entry ID Method Resolution Chain Position Source
7LHV EM 275 A A/B 1-685 PDB
AF-Q9FY46-F1 Predicted AlphaFoldDB

25 variants for Q9FY46

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_4359462_T_C 10 D>G No 1000Genomes
tmp_5_4359423_G_A 23 S>F No 1000Genomes
tmp_5_4359297_G_A 65 A>V No 1000Genomes
ENSVATH06963261 69 R>C No 1000Genomes
tmp_5_4359277_G_T 72 L>I No 1000Genomes
tmp_5_4358727_C_T 139 A>T No 1000Genomes
ENSVATH03053693 167 A>T No 1000Genomes
tmp_5_4358642_G_A 167 A>V No 1000Genomes
tmp_5_4358638_A_T 168 D>E No 1000Genomes
tmp_5_4358636_G_A 169 T>M No 1000Genomes
tmp_5_4358606_A_G 179 I>T No 1000Genomes
tmp_5_4358597_G_C 182 A>G No 1000Genomes
ENSVATH00620522 232 S>G No 1000Genomes
tmp_5_4357836_A_G 255 W>R No 1000Genomes
tmp_5_4357681_G_C 277 A>G No 1000Genomes
tmp_5_4356961_T_C 377 I>M No 1000Genomes
ENSVATH03053689 388 T>A No 1000Genomes
ENSVATH10732443 516 I>V No 1000Genomes
tmp_5_4355973_T_C 526 N>D No 1000Genomes
tmp_5_4355940_T_C 537 I>V No 1000Genomes
tmp_5_4355771_C_T 567 D>N No 1000Genomes
ENSVATH03053687 635 V>I No 1000Genomes
tmp_5_4355508_C_A 654 K>N No 1000Genomes
ENSVATH10732442 665 S>R No 1000Genomes
ENSVATH03053686 679 P>T No 1000Genomes

No associated diseases with Q9FY46

No regional properties for Q9FY46

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9FY46

Functions

Description
EC Number
Subcellular Localization
  • Plastid, chloroplast membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chloroplast membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
secondary active sulfate transmembrane transporter activity Enables the secondary active transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
symporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

15 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A6QNW6 SLC26A8 Testis anion transporter 1 Bos taurus (Bovine) PR
P50443 SLC26A2 Sulfate transporter Homo sapiens (Human) PR
Q86WA9 SLC26A11 Sodium-independent sulfate anion transporter Homo sapiens (Human) PR
Q8TE54 SLC26A7 Anion exchange transporter Homo sapiens (Human) PR
Q96RN1 SLC26A8 Testis anion transporter 1 Homo sapiens (Human) PR
P58743 SLC26A5 Prestin Homo sapiens (Human) PR
Q99NH7 Slc26a5 Prestin Mus musculus (Mouse) PR
Q9R155 Slc26a4 Pendrin Mus musculus (Mouse) PR
Q9WVC8 Slc26a3 Chloride anion exchanger Mus musculus (Mouse) PR
Q8R0C3 Slc26a8 Testis anion transporter 1 Mus musculus (Mouse) PR
Q924C9 Slc26a3 Chloride anion exchanger Rattus norvegicus (Rat) PR
Q9EPH0 Slc26a5 Prestin Rattus norvegicus (Rat) PR
Q02920 Early nodulin-70 Glycine max (Soybean) (Glycine hispida) PR
Q9SV13 SULTR3;1 Sulfate transporter 3.1 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GYH8 SULTR4;2 Probable sulfate transporter 4.2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSYASLSVKD LTSLVSRSGT GSSSSLKPPG QTRPVKVIPL QHPDTSNEAR PPSIPFDDIF
70 80 90 100 110 120
SGWTAKIKRM RLVDWIDTLF PCFRWIRTYR WSEYFKLDLM AGITVGIMLV PQAMSYAKLA
130 140 150 160 170 180
GLPPIYGLYS SFVPVFVYAI FGSSRQLAIG PVALVSLLVS NALGGIADTN EELHIELAIL
190 200 210 220 230 240
LALLVGILEC IMGLLRLGWL IRFISHSVIS GFTSASAIVI GLSQIKYFLG YSIARSSKIV
250 260 270 280 290 300
PIVESIIAGA DKFQWPPFVM GSLILVILQV MKHVGKAKKE LQFLRAAAPL TGIVLGTTIA
310 320 330 340 350 360
KVFHPPSISL VGEIPQGLPT FSFPRSFDHA KTLLPTSALI TGVAILESVG IAKALAAKNR
370 380 390 400 410 420
YELDSNSELF GLGVANILGS LFSAYPATGS FSRSAVNNES EAKTGLSGLI TGIIIGCSLL
430 440 450 460 470 480
FLTPMFKYIP QCALAAIVIS AVSGLVDYDE AIFLWRVDKR DFSLWTITST ITLFFGIEIG
490 500 510 520 530 540
VLVGVGFSLA FVIHESANPH IAVLGRLPGT TVYRNIKQYP EAYTYNGIVI VRIDSPIYFA
550 560 570 580 590 600
NISYIKDRLR EYEVAVDKYT NRGLEVDRIN FVILEMSPVT HIDSSAVEAL KELYQEYKTR
610 620 630 640 650 660
DIQLAISNPN KDVHLTIARS GMVELVGKEW FFVRVHDAVQ VCLQYVQSSN LEDKHLSFTR
670 680
RYGGSNNNSS SSNALLKEPL LSVEK