A6QNW6
Gene name |
SLC26A8 |
Protein name |
Testis anion transporter 1 |
Names |
Anion exchange transporter, Solute carrier family 26 member 8 |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:530509 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6QNW6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6QNW6-F1 | Predicted | AlphaFoldDB |
No variants for A6QNW6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A6QNW6 | |||||
No associated diseases with A6QNW6
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| bicarbonate transmembrane transporter activity | Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-. |
| chloride transmembrane transporter activity | Enables the transfer of chloride ions from one side of a membrane to the other. |
| oxalate transmembrane transporter activity | Enables the transfer of oxalate from one side of a membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals. |
| sulfate transmembrane transporter activity | Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| flagellated sperm motility | The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm. |
| meiotic cell cycle | Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. |
| sperm capacitation | A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium. |
15 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P50443 | SLC26A2 | Sulfate transporter | Homo sapiens (Human) | PR |
| P58743 | SLC26A5 | Prestin | Homo sapiens (Human) | PR |
| Q8TE54 | SLC26A7 | Anion exchange transporter | Homo sapiens (Human) | PR |
| Q86WA9 | SLC26A11 | Sodium-independent sulfate anion transporter | Homo sapiens (Human) | PR |
| Q96RN1 | SLC26A8 | Testis anion transporter 1 | Homo sapiens (Human) | PR |
| Q9R155 | Slc26a4 | Pendrin | Mus musculus (Mouse) | PR |
| Q9WVC8 | Slc26a3 | Chloride anion exchanger | Mus musculus (Mouse) | PR |
| Q99NH7 | Slc26a5 | Prestin | Mus musculus (Mouse) | PR |
| Q8R0C3 | Slc26a8 | Testis anion transporter 1 | Mus musculus (Mouse) | PR |
| Q924C9 | Slc26a3 | Chloride anion exchanger | Rattus norvegicus (Rat) | PR |
| Q9EPH0 | Slc26a5 | Prestin | Rattus norvegicus (Rat) | PR |
| Q02920 | Early nodulin-70 | Glycine max (Soybean) (Glycine hispida) | PR | |
| Q9SV13 | SULTR3;1 | Sulfate transporter 3.1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FY46 | SULTR4;1 | Sulfate transporter 4.1, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GYH8 | SULTR4;2 | Probable sulfate transporter 4.2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQPDRSFQSF | ASRYRQSSFT | YDVKRDVYNE | ENFQQEHRKK | TASSGNVDID | ISTVSHHVQC |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RCSWHKFRRC | LLTVFPFLEW | MCFYRFKDWL | LGDLLAGISV | GLVQIPQVLM | LGLLARHLIP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PLNVSYAAFC | ASVIYGIFGS | CHQMSIGTFF | LVSALAINVL | RTQPFNRGHL | LLGTFIQADF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SNTSFYENYN | RSLSSVASVT | LLTGIIQLSM | GMLGFGFIVA | YIPEAAISAY | LAATALHVML |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SQLTCIFGIM | ISYNSGPIAF | FYNIINYCLG | LPKANSTSIL | LFLTAMVALR | INKCIRISFN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EYPIEFPMEV | FLVLGFAAFS | NKVNMATENS | LMLMEMIPYS | FLFPVTPDMS | NLTEVLIESF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SLALVSSSLL | VFLGKKIASF | HNYDVNSNQD | LIAIGLCNVV | SSFFRSYVFT | GAVARTIIQD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KTGGRQQFAS | LVGAGIMLLL | MMKMARFFYR | LPNAIVAGII | LSNVLPYLEA | VYTLPSLWRQ |
| 490 | 500 | 510 | 520 | 530 | 540 |
| NQYDCLIWMV | TFMSAILLGL | DIGLVVAVTF | AFFIITVQSH | RTKILLLGQI | PNTNIYRSFQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| DYREVANIPG | VKIFQCCNAI | TFVNVHYLKR | KVLEEIEMVK | MPLTEEEIYT | LFSQNEEGAQ |
| 610 | 620 | 630 | 640 | 650 | 660 |
| RGKICRCYCN | CDEPEPSPRV | IYTERYEVQR | GRESSFINLV | RCSRFESMNT | AQTMSEDQVP |
| 670 | 680 | 690 | 700 | 710 | 720 |
| YITSSSSQRN | PNYEEVEKVW | LSDDPSRSMT | ITLPEASDTQ | VRATKLLPYS | TSTILPSIHT |
| 730 | 740 | 750 | 760 | 770 | 780 |
| IILDFSMVHL | VDARALVVLR | QMFSAFQNAN | ILVLIAGCHS | FVVRSLEKND | FFDAGITKAQ |
| 790 | 800 | 810 | 820 | 830 | 840 |
| LFLTLHDAVL | FALSRKLPES | SELSVDESET | VIQETFSETD | KKEESRHKTN | RSLIEAPRSK |
| 850 | 860 | 870 | 880 | 890 | 900 |
| SPGFSLLPDP | EMEEESDLDL | YSTIQMSKDH | GLDLDLDLDR | EVEPESELEP | ESELDQETEL |
| 910 | 920 | 930 | 940 | 950 | |
| EPEPEASPKP | NRQKYWSLFR | AIIPRSPTQT | QARTQSVDRR | HQNVKPYTSK | ADTSEDALEI |