Q8GYH8
PR
Gene name |
SULTR4;2 (At3g12520, MQC3.34, T2E22.36) |
Protein name |
Probable sulfate transporter 4.2 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G12520 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8GYH8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8GYH8-F1 | Predicted | AlphaFoldDB |
59 variants for Q8GYH8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH00319339 | 3 | L>I | No | 1000Genomes | |
| ENSVATH00319339 | 3 | L>V | No | 1000Genomes | |
| ENSVATH02136965 | 17 | K>E | No | 1000Genomes | |
| ENSVATH00319337 | 17 | K>T | No | 1000Genomes | |
| ENSVATH00319336 | 28 | Y>H | No | 1000Genomes | |
| ENSVATH00319335 | 40 | S>F | No | 1000Genomes | |
| ENSVATH05816412 | 43 | F>V | No | 1000Genomes | |
| ENSVATH05816410 | 46 | F>I | No | 1000Genomes | |
| ENSVATH05816409 | 61 | D>E | No | 1000Genomes | |
| tmp_3_3971711_C_T | 61 | D>N | No | 1000Genomes | |
| ENSVATH00319333 | 65 | A>T | No | 1000Genomes | |
| tmp_3_3971686_C_A | 69 | C>F | No | 1000Genomes | |
| tmp_3_3971650_T_A | 81 | Y>F | No | 1000Genomes | |
| tmp_3_3971605_A_G | 96 | L>P | No | 1000Genomes | |
| tmp_3_3971254_C_A | 122 | V>L | No | 1000Genomes | |
| ENSVATH05816395 | 164 | L>V | No | 1000Genomes | |
| tmp_3_3971092_C_A | 176 | E>* | No | 1000Genomes | |
| ENSVATH02136957 | 177 | S>C | No | 1000Genomes | |
| ENSVATH00319324 | 231 | D>E | No | 1000Genomes | |
| ENSVATH00319319 | 269 | R>Q | No | 1000Genomes | |
| ENSVATH02136948 | 349 | E>K | No | 1000Genomes | |
| tmp_3_3969805_T_C | 364 | I>M | No | 1000Genomes | |
| tmp_3_3969592_C_T | 389 | A>T | No | 1000Genomes | |
| ENSVATH10633536 | 390 | K>E | No | 1000Genomes | |
| ENSVATH10633535 | 408 | F>I | No | 1000Genomes | |
| tmp_3_3969516_T_G | 414 | K>T | No | 1000Genomes | |
| tmp_3_3969505_G_A | 418 | Q>* | No | 1000Genomes | |
| ENSVATH10633494 | 440 | F>V | No | 1000Genomes | |
| tmp_3_3968792_C_T | 492 | G>R | No | 1000Genomes | |
| ENSVATH05816371 | 495 | P>Q | No | 1000Genomes | |
| ENSVATH05816370 | 513 | N>D | No | 1000Genomes | |
| tmp_3_3968714_C_T | 518 | V>I | No | 1000Genomes | |
| tmp_3_3968701_G_C | 522 | A>G | No | 1000Genomes | |
| tmp_3_3968702_C_G | 522 | A>P | No | 1000Genomes | |
| ENSVATH05816362 | 537 | R>Q | No | 1000Genomes | |
| ENSVATH05816358 | 544 | D>N | No | 1000Genomes | |
| ENSVATH05816357 | 551 | P>S | No | 1000Genomes | |
| ENSVATH00319306 | 554 | E>V | No | 1000Genomes | |
| tmp_3_3968501_T_G | 560 | I>L | No | 1000Genomes | |
| ENSVATH05816356 | 560 | I>N | No | 1000Genomes | |
| tmp_3_3968236_C_T | 592 | A>T | No | 1000Genomes | |
| tmp_3_3968205_A_G | 602 | L>S | No | 1000Genomes | |
| ENSVATH00319302 | 607 | A>S | No | 1000Genomes | |
| ENSVATH10633440 | 611 | E>D | No | 1000Genomes | |
| ENSVATH05816339 | 612 | L>H | No | 1000Genomes | |
| tmp_3_3968159_C_G | 617 | W>C | No | 1000Genomes | |
| ENSVATH00319297 | 635 | R>I | No | 1000Genomes | |
| ENSVATH00319297 | 635 | R>T | No | 1000Genomes | |
| ENSVATH05816337 | 639 | V>I | No | 1000Genomes | |
| ENSVATH05816335 | 642 | S>I | No | 1000Genomes | |
| ENSVATH05816334 | 645 | P>S | No | 1000Genomes | |
| ENSVATH10633439 | 656 | S>L | No | 1000Genomes | |
| ENSVATH05816333 | 659 | Y>S | No | 1000Genomes | |
| ENSVATH05816332 | 665 | N>K | No | 1000Genomes | |
| tmp_3_3968010_A_C | 667 | V>G | No | 1000Genomes | |
| tmp_3_3968011_C_T | 667 | V>I | No | 1000Genomes | |
| tmp_3_3967992_A_G | 673 | L>S | No | 1000Genomes | |
| ENSVATH05816329 | 676 | E>D | No | 1000Genomes | |
| ENSVATH05816330 | 676 | E>K | No | 1000Genomes |
No associated diseases with Q8GYH8
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| secondary active sulfate transmembrane transporter activity | Enables the secondary active transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. |
| symporter activity | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
15 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A6QNW6 | SLC26A8 | Testis anion transporter 1 | Bos taurus (Bovine) | PR |
| P50443 | SLC26A2 | Sulfate transporter | Homo sapiens (Human) | PR |
| Q86WA9 | SLC26A11 | Sodium-independent sulfate anion transporter | Homo sapiens (Human) | PR |
| Q8TE54 | SLC26A7 | Anion exchange transporter | Homo sapiens (Human) | PR |
| Q96RN1 | SLC26A8 | Testis anion transporter 1 | Homo sapiens (Human) | PR |
| P58743 | SLC26A5 | Prestin | Homo sapiens (Human) | PR |
| Q99NH7 | Slc26a5 | Prestin | Mus musculus (Mouse) | PR |
| Q9R155 | Slc26a4 | Pendrin | Mus musculus (Mouse) | PR |
| Q9WVC8 | Slc26a3 | Chloride anion exchanger | Mus musculus (Mouse) | PR |
| Q8R0C3 | Slc26a8 | Testis anion transporter 1 | Mus musculus (Mouse) | PR |
| Q924C9 | Slc26a3 | Chloride anion exchanger | Rattus norvegicus (Rat) | PR |
| Q9EPH0 | Slc26a5 | Prestin | Rattus norvegicus (Rat) | PR |
| Q02920 | Early nodulin-70 | Glycine max (Soybean) (Glycine hispida) | PR | |
| Q9FY46 | SULTR4;1 | Sulfate transporter 4.1, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SV13 | SULTR3;1 | Sulfate transporter 3.1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSLAVKDLST | ASSSSSKAIP | VKIIPLQYPD | STSSDPHCHS | IPFNDFFSRW | TAKIKRMTFF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DWIDAIFPCF | LWIRTYRWHQ | YFKLDLMAGI | TVGIMLVPQA | MSYARLAGLQ | PIYGLYSSFV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PVFVYAVFGS | SRQLAVGPVA | LVSLLVSNAL | SGIVDPSEEL | YTELAILLAL | MVGIFESIMG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FLRLGWLIRF | ISHSVISGFT | TASAVVIGLS | QLKYFLGYSV | SRSSKIMPVI | DSIIAGADQF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KWPPFLLGCT | ILVILLVMKH | VGKAKKELRF | IRAAGPLTGL | ALGTIIAKVF | HPPSITLVGD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IPQGLPKFSF | PKSFDHAKLL | LPTSALITGV | AILESVGIAK | ALAAKNRYEL | DSNSELFGLG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VANIFGSLFS | AYPTTGSFSR | SAVNSESEAK | TGLSGLVTGI | IIGCSLLFLT | PMFKFIPQCA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LAAIVISAVS | GLVDYEGAIF | LWRVDKRDFT | LWTITSTTTL | FFGIEIGVLI | GVGFSLAFVI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| HESANPHIAV | LGRLPGTTVY | RNMKQYPEAY | TYNGIVIVRI | DAPIYFANIS | YIKDRLREYE |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VAIDKHTSKG | PDMERIYFVI | LEMSPVTYID | SSAVEALKDL | YEEYKTRGIQ | LAISNPNKEV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LLTLARAGIV | ELIGKEWFFV | RVHDAVQVCV | HYVNRPTDVE | ESSKPSLWRR | SGLKNSSTYT |
| 670 | |||||
| EVESNIVLEE | PLLSREK |