Q9D8N0
Gene name |
Eef1g |
Protein name |
Elongation factor 1-gamma |
Names |
EF-1-gamma, eEF-1B gamma |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:67160 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9D8N0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9D8N0-F1 | Predicted | AlphaFoldDB |
10 variants for Q9D8N0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389433290 | 19 | L>P | No | EVA | |
| rs3389503691 | 79 | V>A | No | EVA | |
| rs3389534604 | 80 | S>R | No | EVA | |
| rs36537875 | 89 | P>A | No | EVA | |
| rs3389520181 | 195 | I>F | No | EVA | |
| rs3408556861 | 251 | E>K | No | EVA | |
| rs3409122370 | 269 | A>V | No | EVA | |
| rs1135163560 | 355 | N>D | No | EVA | |
| rs3389520178 | 390 | W>C | No | EVA | |
| rs3389481490 | 413 | V>A | No | EVA |
No associated diseases with Q9D8N0
4 regional properties for Q9D8N0
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| translation elongation factor activity | Functions in chain elongation during polypeptide synthesis at the ribosome. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| response to virus | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. |
| translational elongation | The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. |
16 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2NL00 | GSTT1 | Glutathione S-transferase theta-1 | Bos taurus (Bovine) | PR |
| Q3SZV3 | EEF1G | Elongation factor 1-gamma | Bos taurus (Bovine) | PR |
| A2Q127 | EEF1G | Elongation factor 1-gamma | Equus caballus (Horse) | PR |
| P0CG30 | GSTT2B | Glutathione S-transferase theta-2B | Homo sapiens (Human) | PR |
| P26640 | VARS1 | Valine--tRNA ligase | Homo sapiens (Human) | PR |
| P26641 | EEF1G | Elongation factor 1-gamma | Homo sapiens (Human) | PR |
| Q9Z1Q9 | Vars1 | Valine--tRNA ligase | Mus musculus (Mouse) | PR |
| Q29387 | EEF1G | Elongation factor 1-gamma | Sus scrofa (Pig) | PR |
| Q04462 | Vars1 | Valine--tRNA ligase | Rattus norvegicus (Rat) | PR |
| P30713 | Gstt2 | Glutathione S-transferase theta-2 | Rattus norvegicus (Rat) | PR |
| Q68FR6 | Eef1g | Elongation factor 1-gamma | Rattus norvegicus (Rat) | PR |
| Q5Z627 | Os06g0571400 | Elongation factor 1-gamma 3 | Oryza sativa subsp japonica (Rice) | PR |
| Q9ZRI7 | Os02g0220600 | Elongation factor 1-gamma 1 | Oryza sativa subsp japonica (Rice) | PR |
| Q6YW46 | Os02g0220500 | Elongation factor 1-gamma 2 | Oryza sativa subsp japonica (Rice) | PR |
| P54412 | eef-1G | Probable elongation factor 1-gamma | Caenorhabditis elegans | PR |
| Q6PE25 | eef1g | Elongation factor 1-gamma | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAGTLYTYP | ENWRAFKALI | AAQYSGAQVR | VLSAPPHFHF | GQTNRTPEFL | RKFPAGKVPA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FEGDDGFCVF | ESNAIAYYVS | NEELRGSTPE | AAAQVVQWVS | FADSDIVPPA | STWVFPTLGI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MHHNKQATEN | AKEEVKRILG | LLDTHLKTRT | FLVGERVTLA | DITVVCTLLW | LYKQVLEPSF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RQAFPNTNRW | FLTCINQPQF | RAILGEVKLC | EKMAQFDAKK | FAESQPKKDT | PRKEKGSREE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KQKPQAERKE | EKKAAAPAPE | EEMDECEQAL | AAEPKAKDPF | AHLPKSTFVL | DEFKRKYSNE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DTLSVALPYF | WEHFDKDGWS | LWYAEYRFPE | ELTQTFMSCN | LITGMFQRLD | KLRKNAFASV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ILFGTNNSSS | ISGVWVFRGQ | ELAFPLSPDW | QVDYESYTWR | KLDPGSEETQ | TLVREYFSWE |
| 430 | |||||
| GTFQHVGKAV | NQGKIFK |