Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q29387

Entry ID Method Resolution Chain Position Source
AF-Q29387-F1 Predicted AlphaFoldDB

No variants for Q29387

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q29387

No associated diseases with Q29387

4 regional properties for Q29387

Type Name Position InterPro Accession
domain Elongation factor 1B gamma, C-terminal 270 - 432 IPR001662
domain Glutathione S-transferase, N-terminal 1 - 82 IPR004045
domain Glutathione S-transferase, C-terminal 103 - 193 IPR004046
domain Glutathione S-transferase, C-terminal-like 83 - 211 IPR010987

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome.

1 GO annotations of biological process

Name Definition
translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.

16 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q2NL00 GSTT1 Glutathione S-transferase theta-1 Bos taurus (Bovine) PR
Q3SZV3 EEF1G Elongation factor 1-gamma Bos taurus (Bovine) PR
A2Q127 EEF1G Elongation factor 1-gamma Equus caballus (Horse) PR
P0CG30 GSTT2B Glutathione S-transferase theta-2B Homo sapiens (Human) PR
P26640 VARS1 Valine--tRNA ligase Homo sapiens (Human) PR
P26641 EEF1G Elongation factor 1-gamma Homo sapiens (Human) PR
Q9Z1Q9 Vars1 Valine--tRNA ligase Mus musculus (Mouse) PR
Q9D8N0 Eef1g Elongation factor 1-gamma Mus musculus (Mouse) PR
Q04462 Vars1 Valine--tRNA ligase Rattus norvegicus (Rat) PR
P30713 Gstt2 Glutathione S-transferase theta-2 Rattus norvegicus (Rat) PR
Q68FR6 Eef1g Elongation factor 1-gamma Rattus norvegicus (Rat) PR
Q9ZRI7 Os02g0220600 Elongation factor 1-gamma 1 Oryza sativa subsp japonica (Rice) PR
Q5Z627 Os06g0571400 Elongation factor 1-gamma 3 Oryza sativa subsp japonica (Rice) PR
Q6YW46 Os02g0220500 Elongation factor 1-gamma 2 Oryza sativa subsp japonica (Rice) PR
P54412 eef-1G Probable elongation factor 1-gamma Caenorhabditis elegans PR
Q6PE25 eef1g Elongation factor 1-gamma Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
LYTYPENWRA FKALIAAQYS GAQVRVLSAP PHFHFGQTNH TPEFLRKFPA GKVPAFEGDD
70 80 90 100 110 120
GFCVFESNAI AYYVSNEELR GSTPEAAAQV VQWVSFADSD IVPPASTWVF PTLGIMHYNK
130 140 150 160 170 180
QATENAKDEV RRVLGLLDAH LKTRTFLVGE RVTLADITVV CTLLWLYKQV LEPSFRQAFP
190 200 210 220 230 240
NTNRWFLTCI NQPQFRAVLG EVKLCEKMAQ FDAKKFAESQ PKKDTPRKEK GSREEKQKPQ
250 260 270 280 290 300
AERKEEKKAA APAPEEELDE CEQALAAEPK AKDPFAHLPK STFVLDEFKR KYSNEDTLSV
310 320 330 340 350 360
ALPYFWEHFD KDGWSLWYSE YRFPEELTQT FMSCNLITGM FQRLDKLRKN AFASVILFGT
370 380 390 400 410 420
NNSSSISGVW VFRGQELAFP LSPDWQVDYE SYTWRKLDPG SEETQTLVRE YFSWEGAYQH
430
VGKAFNQGKI FK