A2Q127

PR
Gene name
EEF1G
Protein name
Elongation factor 1-gamma
Names
EF-1-gamma, eEF-1B gamma
Species
Equus caballus (Horse)
KEGG Pathway
ecb:100009686
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

185-309 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2Q127

Entry ID Method Resolution Chain Position Source
AF-A2Q127-F1 Predicted AlphaFoldDB

No variants for A2Q127

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2Q127

No associated diseases with A2Q127

4 regional properties for A2Q127

Type Name Position InterPro Accession
domain Elongation factor 1B gamma, C-terminal 275 - 437 IPR001662
domain Glutathione S-transferase, N-terminal 2 - 87 IPR004045
domain Glutathione S-transferase, C-terminal 108 - 198 IPR004046
domain Glutathione S-transferase, C-terminal-like 88 - 216 IPR010987

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome.

1 GO annotations of biological process

Name Definition
translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.

9 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3SZV3 EEF1G Elongation factor 1-gamma Bos taurus (Bovine) PR
P26641 EEF1G Elongation factor 1-gamma Homo sapiens (Human) PR
Q9D8N0 Eef1g Elongation factor 1-gamma Mus musculus (Mouse) PR
Q29387 EEF1G Elongation factor 1-gamma Sus scrofa (Pig) PR
Q68FR6 Eef1g Elongation factor 1-gamma Rattus norvegicus (Rat) PR
Q5Z627 Os06g0571400 Elongation factor 1-gamma 3 Oryza sativa subsp japonica (Rice) PR
Q6YW46 Os02g0220500 Elongation factor 1-gamma 2 Oryza sativa subsp japonica (Rice) PR
P54412 eef-1G Probable elongation factor 1-gamma Caenorhabditis elegans PR
Q6PE25 eef1g Elongation factor 1-gamma Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MAAGTLYTYP ENWRAFKALI AAQYSGAQVR VLSAPPHFHF GQTNRTPEFL RKFPAGKVPA
70 80 90 100 110 120
FEGDDGFCVF ESNAIAYYVS NEELRGSTPE AAAQVVQWVS FADSDIVPPA STWVFPTLGI
130 140 150 160 170 180
MHHNKQATEN AKEEVRRILG LLDAHLKTRT FLVGERVTLA DITVVCTLLW LYKQVLEPSF
190 200 210 220 230 240
RQAFPNTNRW FLTCINQPQF RAVLGEVKLC EKMAQFDAKK FAESQPKKDT PRKEKGSREE
250 260 270 280 290 300
KQKPQAERKE EKKAAAPAPE EEMDECEQAL AAEPKAKDPF AHLPKSTFVL DEFKRKYSNE
310 320 330 340 350 360
DTLSVALPYF WEHFDKDGWS LWYSEYRFPE ELTQTFMSCN LITGMFQRLD KLRKNAFASV
370 380 390 400 410 420
ILFGTNNSSS ISGVWVFRGQ ELAFPLSPDW QVDYESYTWR KLDPGSEEAQ TLVREYFSWE
430
GAFQHVGKAF NQGKIFK