Q9D2L5
Gene name |
Cpxm2 (Cpx2) |
Protein name |
Inactive carboxypeptidase-like protein X2 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:55987 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9D2L5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9D2L5-F1 | Predicted | AlphaFoldDB |
No variants for Q9D2L5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9D2L5 | |||||
No associated diseases with Q9D2L5
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metallocarboxypeptidase activity | Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. |
| zinc ion binding | Binding to a zinc ion (Zn). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| peptide metabolic process | The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. |
| protein processing | Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein. |
16 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P04836 | CPE | Carboxypeptidase E | Bos taurus (Bovine) | PR |
| Q2KJ83 | CPN1 | Carboxypeptidase N catalytic chain | Bos taurus (Bovine) | PR |
| Q8QGP3 | CPZ | Carboxypeptidase Z | Gallus gallus (Chicken) | PR |
| Q8IUX7 | AEBP1 | Adipocyte enhancer-binding protein 1 | Homo sapiens (Human) | PR |
| O75976 | CPD | Carboxypeptidase D | Homo sapiens (Human) | PR |
| Q66K79 | CPZ | Carboxypeptidase Z | Homo sapiens (Human) | PR |
| Q96SM3 | CPXM1 | Probable carboxypeptidase X1 | Homo sapiens (Human) | PR |
| P14384 | CPM | Carboxypeptidase M | Homo sapiens (Human) | PR |
| Q8N436 | CPXM2 | Inactive carboxypeptidase-like protein X2 | Homo sapiens (Human) | PR |
| Q80V42 | Cpm | Carboxypeptidase M | Mus musculus (Mouse) | PR |
| Q9Z100 | Cpxm1 | Probable carboxypeptidase X1 | Mus musculus (Mouse) | PR |
| Q640N1 | Aebp1 | Adipocyte enhancer-binding protein 1 | Mus musculus (Mouse) | PR |
| Q9JJN5 | Cpn1 | Carboxypeptidase N catalytic chain | Mus musculus (Mouse) | PR |
| O89001 | Cpd | Carboxypeptidase D | Mus musculus (Mouse) | PR |
| Q9EQV8 | Cpn1 | Carboxypeptidase N catalytic chain | Rattus norvegicus (Rat) | PR |
| A2RUV9 | Aebp1 | Adipocyte enhancer-binding protein 1 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARLGTACPA | LALALALVAV | ALAGVRAQGA | AFEEPDYYSQ | ELWRRGRYYG | HPEPEPEQEL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FSPSMHEDLR | VEEQEQQEPH | QQGHRTPKKA | IKPKKAPKRE | KLVAETPPPG | KNSNRKGRRS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KNLEKAASDD | HGVPVAHEDV | RESCPPLGLE | TLKITDFQLH | ASTSKRYGLG | AHRGRLNIQA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GINENDFYDG | AWCAGRNDLH | QWIEVDARRL | TKFTGVITQG | RNSLWLSDWV | TSYKVMVSND |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SHTWVTVKNG | SGDMIFEGNS | EKEIPVLNEL | PVPMVARYIR | INPQSWFDNG | SICMRMEILG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| CPLPDPNNYY | HRRNEMTTTD | DLDFKHHNYK | EMRQLMKVVN | EMCPNITRIY | NIGKSHQGLK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LYAVEISDHP | GEHEVGEPEF | HYIAGAHGNE | VLGRELLLLL | LHFLCQEYSA | QNARIVRLVE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ETRIHILPSL | NPDGYEKAYE | GGSELGGWSL | GRWTHDGIDI | NNNFPDLNSL | LWEAEDQQNA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PRKVPNHYIA | IPEWFLSENA | TVATETRAVI | AWMEKIPFVL | GGNLQGGELV | VAYPYDMVRS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LWKTQEHTPT | PDDHVFRWLA | YSYASTHRLM | TDARRRVCHT | EDFQKEEGTV | NGASWHTVAG |
| 610 | 620 | 630 | 640 | 650 | 660 |
| SLNDFSYLHT | NCFELSIYVG | CDKYPHESEL | PEEWENNRES | LIVFMEQVHR | GIKGIVRDLQ |
| 670 | 680 | 690 | 700 | 710 | 720 |
| GKGISNAVIS | VEGVNHDIRT | ASDGDYWRLL | NPGEYVVTAK | AEGFITSTKN | CMVGYDMGAT |
| 730 | 740 | 750 | 760 | ||
| RCDFTLTKTN | LARIREIMET | FGKQPVSLPS | RRLKLRGRKR | RQRG |