Q8N436
PR
Gene name |
CPXM2 (CPX2, UNQ676/PRO1310) |
Protein name |
Inactive carboxypeptidase-like protein X2 |
Names |
|
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:119587 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8N436
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8N436-F1 | Predicted | AlphaFoldDB |
745 variants for Q8N436
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs869025241 RCV000207192 CA351544 |
166 | G>E | Variant assessed as Somatic; impact. Ductal breast carcinoma [NCI-TCGA, ClinVar] | Yes |
ClinGen ClinVar Ensembl NCI-TCGA dbSNP |
|
CA378898287 rs1231688335 |
3 | R>L | No |
ClinGen TOPMed |
|
|
rs1427529014 CA378898281 |
4 | P>L | No |
ClinGen gnomAD |
|
|
CA378898282 rs1427529014 |
4 | P>R | No |
ClinGen gnomAD |
|
|
CA378898276 rs1012503053 |
5 | G>E | No |
ClinGen TOPMed gnomAD |
|
|
rs1012503053 CA215572457 |
5 | G>V | No |
ClinGen TOPMed gnomAD |
|
|
CA378898275 rs1478230543 |
6 | T>A | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1369386652 CA378898270 |
6 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs959209257 CA215572456 |
7 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA5732666 rs112027854 COSM1560901 |
9 | P>L | large_intestine [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
rs1192063574 CA378898251 |
10 | A>S | No |
ClinGen TOPMed |
|
|
CA378898248 rs1325405878 |
10 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA378898244 rs1260961224 |
11 | L>P | No |
ClinGen gnomAD |
|
|
rs201350090 CA5732665 |
12 | A>D | No |
ClinGen ExAC gnomAD |
|
|
CA378898216 rs1379993891 |
16 | L>P | No |
ClinGen gnomAD |
|
|
rs1361946520 CA378898214 |
17 | A>P | No |
ClinGen gnomAD |
|
|
rs1046113962 CA215572453 |
17 | A>V | No |
ClinGen TOPMed |
|
|
CA378898187 rs1590107082 |
22 | G>W | No |
ClinGen Ensembl |
|
|
rs112646528 CA378898181 |
23 | V>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA5732664 rs112646528 |
23 | V>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1010235381 CA215572452 |
24 | G>R | No |
ClinGen TOPMed gnomAD |
|
|
CA378898149 rs1466360909 |
28 | A>S | No |
ClinGen TOPMed gnomAD |
|
|
CA378898151 rs1466360909 |
28 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA378898138 rs1168480109 |
30 | L>V | No |
ClinGen gnomAD |
|
|
CA378898122 rs766664971 |
32 | D>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732662 rs553797182 |
32 | D>E | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA5732663 rs766664971 |
32 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1427993831 CA378898123 |
32 | D>Y | No |
ClinGen gnomAD |
|
|
rs894811159 CA215572451 |
33 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs894811159 CA378898115 |
33 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
CA378898119 rs1462546568 |
33 | P>S | No |
ClinGen gnomAD |
|
|
CA378898096 rs1480777193 |
36 | Y>H | No |
ClinGen gnomAD |
|
|
CA5732661 rs143257438 |
38 | Q>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1564815470 CA378898077 |
39 | E>K | No |
ClinGen Ensembl |
|
|
rs1306424820 CA378898060 |
41 | W>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1306424820 CA378898062 |
41 | W>R | No |
ClinGen TOPMed gnomAD |
|
|
rs936347610 CA215572450 |
42 | S>G | No |
ClinGen Ensembl |
|
|
CA378898044 rs1381156771 |
43 | R>Q | No |
ClinGen gnomAD |
|
|
rs1248837480 CA378898045 |
43 | R>W | No |
ClinGen gnomAD |
|
|
rs1336545843 CA378898028 |
45 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1392303751 CA378898019 |
47 | Y>H | No |
ClinGen gnomAD |
|
|
rs1296657491 CA378898009 |
48 | A>S | No |
ClinGen gnomAD |
|
|
CA378898011 rs1296657491 |
48 | A>T | No |
ClinGen gnomAD |
|
|
rs768048796 CA5732660 |
48 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1426414905 CA378898004 |
49 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA378898002 COSM1474441 rs761287092 |
49 | R>H | breast [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA5732659 rs761287092 |
49 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378897996 rs1165504457 |
50 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1165504457 CA378897997 |
50 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1054510798 CA215572449 |
51 | E>G | No |
ClinGen TOPMed |
|
|
rs1446422259 CA378897983 |
52 | P>L | No |
ClinGen gnomAD |
|
| TCGA novel | 53 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs751125936 CA5732658 |
53 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs942874685 CA215572447 |
54 | L>V | No |
ClinGen TOPMed |
|
|
CA378897951 rs1252331832 |
57 | F>C | No |
ClinGen gnomAD |
|
|
rs911419370 CA215572446 |
57 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1279479818 CA378897955 |
57 | F>L | No |
ClinGen TOPMed |
|
|
rs762529185 CA5732656 |
59 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs934264986 CA215572444 |
60 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA378897936 rs1590106912 |
60 | P>S | No |
ClinGen Ensembl |
|
|
CA378897919 rs1357983128 |
63 | A>E | No |
ClinGen gnomAD |
|
|
rs1042714692 CA215572442 |
66 | G>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1042714692 CA378897903 |
66 | G>W | No |
ClinGen TOPMed gnomAD |
|
|
rs573651187 CA5732654 |
67 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378897886 rs1349339422 |
68 | E>D | No |
ClinGen gnomAD |
|
|
CA5732653 rs555958103 |
69 | W>* | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA378897882 rs1590106871 |
69 | W>G | No |
ClinGen Ensembl |
|
|
rs1305075975 CA378897873 |
70 | E>G | No |
ClinGen gnomAD |
|
|
rs1422816998 CA378897867 COSM3382722 |
71 | R>W | pancreas [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
rs962374194 CA215572441 |
72 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs776688409 CA5732652 |
72 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs909638407 CA378897834 |
76 | P>H | No |
ClinGen TOPMed gnomAD |
|
|
CA215572440 rs909638407 |
76 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1418194011 CA378897832 |
77 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1590106835 CA378897830 |
77 | R>K | No |
ClinGen Ensembl |
|
|
CA378897820 rs1269121549 |
78 | P>L | No |
ClinGen gnomAD |
|
|
CA5732650 rs748236733 |
81 | R>K | No |
ClinGen ExAC gnomAD |
|
|
rs779140546 CA5732649 |
83 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA378897778 rs1299537656 |
85 | P>T | No |
ClinGen TOPMed |
|
|
CA5732648 rs749492502 |
86 | K>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1238742629 CA378897769 |
86 | K>N | No |
ClinGen gnomAD |
|
|
rs749492502 CA5732647 |
86 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA215572436 rs985537403 |
88 | A>V | No |
ClinGen Ensembl |
|
|
TCGA novel rs780425479 CA5732646 |
90 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC gnomAD NCI-TCGA |
|
CA378897740 rs1285414559 |
91 | R>K | No |
ClinGen gnomAD |
|
|
rs201232023 CA215572435 |
91 | R>S | No |
ClinGen 1000Genomes gnomAD |
|
|
CA5732645 rs756402607 |
92 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA215572433 rs756402607 |
92 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 93 | K>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 94 | S>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378897718 rs1319016378 |
94 | S>W | No |
ClinGen gnomAD |
|
| TCGA novel | 95 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1156639615 CA378897705 |
96 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1387013410 CA378897708 |
96 | P>S | No |
ClinGen gnomAD |
|
|
rs1429631580 CA378897700 |
97 | E>G | No |
ClinGen TOPMed gnomAD |
|
|
CA378897704 rs1456507752 |
97 | E>K | No |
ClinGen gnomAD |
|
|
CA378897703 rs1456507752 |
97 | E>Q | No |
ClinGen gnomAD |
|
|
rs1429631580 CA378897701 |
97 | E>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1201153752 CA378897691 |
98 | P>Q | No |
ClinGen gnomAD |
|
|
rs1288299116 CA378897696 |
98 | P>T | No |
ClinGen TOPMed |
|
|
CA215572432 rs374015354 |
99 | P>A | No |
ClinGen gnomAD |
|
|
CA378897689 rs374015354 |
99 | P>S | No |
ClinGen gnomAD |
|
|
CA378897684 rs1193216339 |
100 | P>A | No |
ClinGen gnomAD |
|
|
rs1204975059 CA378897674 |
101 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1204975059 CA378897676 |
101 | P>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1260255116 CA378897677 |
101 | P>S | No |
ClinGen gnomAD |
|
|
CA378897672 rs750831501 |
102 | G>C | No |
ClinGen ExAC gnomAD |
|
|
rs537345976 CA5732628 |
102 | G>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA5732644 rs750831501 |
102 | G>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 103 | K>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378897649 rs1182199264 |
104 | H>Y | No |
ClinGen gnomAD |
|
|
rs746224473 CA5732627 |
106 | N>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs781539249 CA5732626 |
107 | K>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs757714999 CA5732625 |
108 | K>E | No |
ClinGen ExAC gnomAD |
|
|
CA378897614 rs1590095473 TCGA novel |
108 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA5732623 rs757828512 CA5732622 |
110 | M>I | No |
ClinGen ExAC gnomAD |
|
|
CA5732624 rs752095775 |
110 | M>L | No |
ClinGen ExAC gnomAD |
|
|
rs761693848 CA215571108 |
113 | K>N | No |
ClinGen Ensembl |
|
|
CA5732621 rs145829011 |
113 | K>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs754664405 CA5732619 |
117 | K>M | No |
ClinGen ExAC gnomAD |
|
|
rs753631030 CA5732618 |
118 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732617 rs576070966 |
118 | A>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1279879025 CA378897544 |
119 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1260144824 CA378897543 |
120 | N>D | No |
ClinGen TOPMed |
|
|
CA5732616 rs760648493 |
120 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs762923770 CA5732613 |
121 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA5732614 rs777549768 |
121 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA215571107 rs963455416 |
122 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
CA378897528 rs1260832701 |
122 | D>Y | No |
ClinGen TOPMed |
|
|
CA5732612 rs775702927 |
124 | S>G | No |
ClinGen ExAC gnomAD |
|
|
rs769837934 CA5732611 |
124 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs202210136 CA5732610 |
126 | R>C | Variant assessed as Somatic; 4.621e-05 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 126 | R>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA5732609 rs776943296 |
126 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378897500 rs776943296 |
126 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1200313242 CA378897496 |
127 | V>E | No |
ClinGen gnomAD |
|
|
COSM915785 rs771257066 CA5732608 |
129 | R>C | endometrium [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA5732607 rs141445034 |
129 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5732605 rs759010894 |
130 | E>* | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 130 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378897123 rs1175529085 |
135 | S>N | No |
ClinGen gnomAD |
|
|
CA378897056 rs1564803239 |
139 | L>F | No |
ClinGen Ensembl |
|
|
rs1464727426 CA378897044 |
140 | G>R | No |
ClinGen gnomAD |
|
|
CA378897030 rs1554886820 |
140 | G>V | No |
ClinGen Ensembl |
|
|
CA378897007 rs1188212471 |
142 | E>G | No |
ClinGen gnomAD |
|
|
rs1240062869 CA378897014 |
142 | E>Q | No |
ClinGen gnomAD |
|
|
rs754506196 CA5732583 |
143 | T>N | No |
ClinGen ExAC gnomAD |
|
|
CA5732581 rs529297000 |
145 | K>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1321801346 CA378896906 |
148 | D>H | No |
ClinGen gnomAD |
|
|
rs1307570894 CA378896898 |
148 | D>V | No |
ClinGen gnomAD |
|
| TCGA novel | 148 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378896890 rs1297043986 |
149 | F>L | No |
ClinGen gnomAD |
|
|
CA378896870 rs1348214543 |
150 | Q>* | No |
ClinGen Ensembl |
|
| TCGA novel | 150 | Q>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1226869779 CA378896852 |
151 | L>F | No |
ClinGen gnomAD |
|
|
rs750116155 CA5732578 |
151 | L>H | No |
ClinGen ExAC gnomAD |
|
|
rs781050994 CA5732577 |
152 | H>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs767306722 CA215569073 |
155 | T>A | No |
ClinGen Ensembl |
|
|
CA378896795 rs146535848 |
155 | T>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
COSM361525 CA5732576 rs146535848 |
155 | T>M | lung central_nervous_system [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
rs761486980 CA5732574 |
158 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732573 rs144205490 |
158 | R>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA5732572 rs144205490 |
158 | R>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 158 | R>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA215569072 rs111710722 |
159 | Y>N | No |
ClinGen Ensembl |
|
|
COSM1249081 rs139562473 CA5732570 |
160 | G>S | oesophagus [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
rs1184045171 CA378896758 |
161 | L>P | No |
ClinGen gnomAD |
|
|
rs768037995 CA5732568 |
163 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA215569070 rs763012968 |
164 | H>R | No |
ClinGen TOPMed |
|
|
rs936864859 CA215569071 |
164 | H>Y | No |
ClinGen TOPMed |
|
|
CA5732566 rs373499345 |
165 | R>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5732565 rs373499345 |
165 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs144190123 CA378896739 |
165 | R>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs144190123 CA5732564 |
165 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA215569069 rs1051148040 |
167 | R>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1202370101 CA378896730 |
167 | R>T | No |
ClinGen gnomAD |
|
|
CA378896722 rs1316327552 |
168 | L>P | No |
ClinGen gnomAD |
|
|
CA378896718 rs1339079664 |
169 | N>Y | No |
ClinGen gnomAD |
|
|
CA215569068 rs546029958 |
171 | Q>R | No |
ClinGen 1000Genomes |
|
|
rs758287087 CA5732535 |
172 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed |
|
CA5732534 COSM167721 rs200954130 |
172 | A>V | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs776975412 CA215258328 |
173 | G>A | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA5732531 rs776975412 |
173 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs756193715 CA5732532 |
173 | G>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 175 | N>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 175 | N>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378636648 rs1318243446 |
176 | E>* | No |
ClinGen gnomAD |
|
|
rs1456426681 CA378636602 |
178 | D>Y | No |
ClinGen gnomAD |
|
|
rs912758409 CA215258312 |
180 | Y>C | No |
ClinGen Ensembl |
|
|
rs62640881 CA5732530 |
180 | Y>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs17679897 CA378636520 |
181 | D>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs779999511 CA5732528 |
182 | G>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1564793846 CA378636479 |
183 | A>T | No |
ClinGen Ensembl |
|
|
CA5732527 rs764574900 |
183 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1227507322 CA378636427 |
185 | C>Y | No |
ClinGen TOPMed |
|
|
rs759082507 CA215258247 |
186 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732524 rs765724121 |
186 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs759082507 CA5732523 |
186 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1265218160 CA378636379 |
187 | G>R | No |
ClinGen gnomAD |
|
|
CA215258235 rs1014536981 |
188 | R>G | No |
ClinGen gnomAD |
|
|
rs1163113077 CA378636350 |
189 | N>D | No |
ClinGen Ensembl |
|
|
rs1344401589 CA378636339 |
189 | N>T | No |
ClinGen gnomAD |
|
|
CA378636327 rs1290565658 |
190 | D>N | No |
ClinGen TOPMed |
|
|
rs1368630623 CA378636301 |
191 | L>F | No |
ClinGen gnomAD |
|
|
CA378636292 rs1270802090 |
191 | L>P | No |
ClinGen gnomAD |
|
|
CA5732520 rs746690533 |
194 | W>* | No |
ClinGen ExAC gnomAD |
|
|
rs770563227 CA5732521 |
194 | W>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 195 | I>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1295183342 CA378636141 |
198 | D>Y | No |
ClinGen gnomAD |
|
| TCGA novel | 199 | A>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378636112 rs1488641334 |
199 | A>S | No |
ClinGen TOPMed |
|
|
CA378636104 rs772955304 |
200 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1406441755 CA378636090 |
200 | R>P | No |
ClinGen TOPMed gnomAD |
|
|
rs1406441755 CA378636091 |
200 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA5732519 rs772955304 |
200 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732517 rs137943270 |
201 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5732516 rs367714651 |
201 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5732515 rs754934044 |
204 | R>G | No |
ClinGen ExAC gnomAD |
|
|
rs150318218 CA5732514 |
204 | R>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs781144431 CA5732513 |
206 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378636026 rs111800333 |
207 | G>A | No |
ClinGen gnomAD |
|
|
rs111800333 CA215258172 |
207 | G>D | No |
ClinGen gnomAD |
|
|
rs376943268 CA5732512 |
209 | I>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs915611587 CA215258168 |
210 | T>A | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs751859621 CA5732511 |
211 | Q>R | No |
ClinGen ExAC |
|
|
rs1382458468 CA378635997 |
212 | G>E | No |
ClinGen TOPMed |
|
|
rs1442007126 CA378635992 |
213 | R>K | No |
ClinGen gnomAD |
|
|
rs761792844 CA215258138 |
214 | N>I | No |
ClinGen ExAC gnomAD |
|
|
CA5732510 rs761792844 |
214 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs1434092890 CA378635974 |
216 | L>F | No |
ClinGen TOPMed |
|
|
rs1196819986 CA378629725 |
219 | S>G | No |
ClinGen gnomAD |
|
|
rs753053187 CA5732488 |
221 | W>L | No |
ClinGen ExAC |
|
|
rs200791860 CA5732489 |
221 | W>R | No |
ClinGen 1000Genomes ExAC |
|
|
rs755474622 CA5732486 |
222 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755474622 CA5732487 |
222 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378629670 rs1473293680 |
223 | T>A | No |
ClinGen TOPMed gnomAD |
|
|
rs1251824151 CA378629662 |
224 | S>T | No |
ClinGen gnomAD |
|
|
CA378629615 rs1248591770 |
227 | V>I | No |
ClinGen TOPMed |
|
|
rs140219726 CA5732484 |
229 | V>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5732483 rs140219726 |
229 | V>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5732482 rs749999619 |
233 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732481 rs375551890 |
235 | T>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA215220671 rs375551890 |
235 | T>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5732479 rs774146335 |
236 | W>R | No |
ClinGen ExAC gnomAD |
|
|
rs768367175 CA5732478 |
237 | V>F | No |
ClinGen ExAC gnomAD |
|
|
rs1409104850 CA378629324 |
242 | G>R | No |
ClinGen gnomAD |
|
|
CA5732476 rs775266168 CA5732477 |
246 | M>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA215220628 rs892164439 |
246 | M>V | No |
ClinGen Ensembl |
|
|
rs1477626468 CA378629083 |
247 | I>M | No |
ClinGen gnomAD |
|
|
rs1189428221 CA378629095 |
247 | I>V | No |
ClinGen gnomAD |
|
|
rs1458667738 CA378629078 |
248 | F>V | No |
ClinGen TOPMed |
|
|
CA5732463 rs561979130 |
249 | E>A | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1210324555 CA378629046 |
250 | G>E | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA378629023 rs1165211004 |
252 | S>N | No |
ClinGen TOPMed |
|
|
rs201670839 CA215219576 |
255 | E>V | No |
ClinGen Ensembl |
|
|
CA378628949 rs1564774544 |
258 | V>I | No |
ClinGen Ensembl |
|
| TCGA novel | 260 | N>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378628892 rs1210313339 |
262 | L>V | No |
ClinGen gnomAD |
|
|
rs994025078 CA215219551 |
263 | P>L | No |
ClinGen Ensembl |
|
|
CA378628867 rs1219185190 |
264 | V>D | No |
ClinGen gnomAD |
|
|
CA5732455 rs199927775 |
264 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed |
|
CA378628860 rs1564774485 |
265 | P>A | No |
ClinGen Ensembl |
|
|
rs1366533225 CA378628856 |
265 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1366533225 CA378628857 |
265 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
rs773389892 CA5732453 |
267 | V>A | No |
ClinGen ExAC gnomAD |
|
|
CA5732451 COSM1346543 rs368914654 |
269 | R>C | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs368914654 CA5732450 |
269 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs774426425 CA5732449 |
269 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA5732448 rs748247193 |
270 | Y>* | No |
ClinGen ExAC gnomAD |
|
|
COSM381818 rs146633990 CA5732447 |
272 | R>C | lung oesophagus [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
rs749545644 CA5732446 COSM915783 |
272 | R>H | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA378628761 rs749545644 |
272 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378628754 rs1256978206 |
273 | I>L | No |
ClinGen TOPMed |
|
|
CA5732444 rs144549153 |
274 | N>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5732443 rs746404523 |
275 | P>A | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 276 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1190339989 CA378628711 |
276 | Q>P | No |
ClinGen gnomAD |
|
|
CA5732442 rs781693992 |
277 | S>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1247110502 CA378628666 |
279 | F>S | No |
ClinGen gnomAD |
|
| TCGA novel | 280 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs756698375 CA5732441 |
281 | N>T | No |
ClinGen ExAC gnomAD |
|
|
CA378628614 rs1484003432 |
283 | S>N | No |
ClinGen gnomAD |
|
|
rs140492343 CA5732440 |
284 | I>V | No |
ClinGen ESP ExAC gnomAD |
|
|
CA5732439 rs763587964 |
285 | C>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs374576387 CA5732438 |
287 | R>S | No |
ClinGen ESP ExAC gnomAD |
|
|
CA378628571 rs1362237875 |
289 | E>Q | No |
ClinGen TOPMed |
|
|
rs1159080225 CA378628554 |
291 | L>P | No |
ClinGen TOPMed |
|
|
CA378628551 rs1405734952 |
292 | G>R | No |
ClinGen gnomAD |
|
|
rs765155654 CA5732436 |
293 | C>F | No |
ClinGen ExAC gnomAD |
|
|
rs1432848663 CA378628538 |
294 | P>A | No |
ClinGen TOPMed |
|
|
CA5732434 rs776692250 |
296 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
| TCGA novel | 298 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378627620 rs1247435269 |
298 | P>R | No |
ClinGen gnomAD |
|
|
rs777365472 CA5732422 |
299 | N>D | No |
ClinGen ExAC gnomAD |
|
|
rs1312299629 CA378627611 |
300 | N>D | No |
ClinGen gnomAD |
|
|
CA5732420 rs752370453 |
301 | Y>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs757948905 CA5732421 |
301 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732419 rs765035229 |
302 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA215205875 rs78879045 |
303 | H>P | No |
ClinGen Ensembl |
|
|
rs145723018 CA5732418 |
304 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA5732417 rs376038492 |
304 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA5732415 COSM374872 rs370358833 |
305 | R>Q | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs372846460 CA5732416 |
305 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs764262720 CA5732413 |
306 | N>D | No |
ClinGen ExAC gnomAD |
|
|
CA5732414 rs764262720 |
306 | N>H | No |
ClinGen ExAC gnomAD |
|
|
CA215205855 rs376249274 |
306 | N>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5732411 rs775667656 |
307 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs751380071 CA215205848 |
307 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs770057188 CA5732410 |
308 | M>R | No |
ClinGen ExAC gnomAD |
|
|
rs776218004 CA215205836 |
311 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA378627517 rs1564765441 |
315 | D>Y | No |
ClinGen Ensembl |
|
|
rs1268649078 CA378627502 |
316 | F>L | No |
ClinGen gnomAD |
|
| TCGA novel | 317 | K>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs776994597 CA5732408 |
318 | H>N | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 319 | H>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs771296124 CA5732407 |
319 | H>R | No |
ClinGen ExAC gnomAD |
|
|
CA5732406 rs747583183 |
320 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs939649167 CA215205820 |
321 | Y>C | No |
ClinGen gnomAD |
|
|
CA378627443 rs1227859179 |
324 | M>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs778184898 CA5732405 |
324 | M>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs747723133 COSM915780 CA5732404 |
325 | R>C | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs754686014 CA5732401 COSM915779 |
325 | R>H | Variant assessed as Somatic; 0.0 impact. large_intestine endometrium haematopoietic_and_lymphoid_tissue [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs754686014 CA5732402 |
325 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs747723133 CA5732403 |
325 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732400 rs779919295 |
326 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
rs1395009327 CA378636813 |
329 | K>Q | No |
ClinGen gnomAD |
|
|
rs1189681043 CA378636808 |
329 | K>T | No |
ClinGen gnomAD |
|
|
rs1451737318 CA378636799 |
331 | V>M | No |
ClinGen gnomAD |
|
|
rs751886826 CA215200802 |
332 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
CA378636751 rs1280872186 |
334 | M>T | No |
ClinGen gnomAD |
|
|
CA215200800 rs952737994 |
336 | P>L | No |
ClinGen TOPMed |
|
|
CA5732376 rs376372536 |
337 | N>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5732375 rs757189750 |
338 | I>V | No |
ClinGen ExAC |
|
|
rs752725785 CA5732374 |
339 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA5732373 rs765333969 |
339 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 341 | I>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378636591 rs1367136389 |
342 | Y>* | No |
ClinGen gnomAD |
|
|
CA378636594 rs1228965552 |
342 | Y>C | No |
ClinGen gnomAD |
|
|
rs1295070123 CA378636565 |
343 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
CA5732372 rs557565980 |
344 | I>M | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA378636543 rs1429651881 |
344 | I>T | No |
ClinGen gnomAD |
|
| TCGA novel | 345 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378636438 rs1335700297 |
349 | Q>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1305646256 CA378636424 |
350 | G>S | No |
ClinGen TOPMed |
|
| TCGA novel | 351 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1393783351 CA378636395 |
352 | K>Q | No |
ClinGen gnomAD |
|
|
CA5732371 rs754069945 |
354 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378636359 rs754069945 |
354 | Y>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378636367 rs1374265874 |
354 | Y>H | No |
ClinGen gnomAD |
|
| TCGA novel | 355 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs761101657 CA5732369 |
360 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA5732367 rs768013289 |
363 | G>A | No |
ClinGen ExAC gnomAD |
|
|
CA378636139 rs1485387794 |
364 | E>V | No |
ClinGen gnomAD |
|
|
CA5732366 rs149790654 |
365 | H>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs149790654 CA215200793 |
365 | H>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5732365 rs773956192 |
366 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs139790511 | 367 | V>= | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA5732363 rs201099744 |
368 | G>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs201099744 CA5732362 |
368 | G>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs1348025071 CA378635625 |
370 | P>H | No |
ClinGen TOPMed gnomAD |
|
|
rs776387177 CA5732341 |
371 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732340 rs770692756 |
372 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs1461159406 CA378635579 |
373 | H>D | No |
ClinGen TOPMed gnomAD |
|
|
CA5732339 rs746866224 |
373 | H>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs746866224 CA378635575 |
373 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378635555 rs1161541708 |
374 | Y>H | No |
ClinGen gnomAD |
|
|
CA5732338 rs568542152 |
376 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
COSM915778 CA5732337 rs199923458 |
376 | A>V | endometrium [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
CA378635458 rs1468395470 |
377 | G>E | No |
ClinGen TOPMed |
|
| TCGA novel | 378 | A>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA5732334 rs780023934 |
378 | A>T | No |
ClinGen ExAC |
|
|
rs868029784 CA215200406 |
380 | G>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA5732332 rs202065646 |
381 | N>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA378635337 rs1268383279 |
382 | E>G | No |
ClinGen gnomAD |
|
|
CA378635296 rs1210132382 |
383 | V>G | No |
ClinGen gnomAD |
|
|
rs200536913 CA215200403 COSM340855 |
383 | V>L | lung [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
rs200536913 CA215200404 |
383 | V>M | No |
ClinGen TOPMed |
|
|
CA378635264 rs1314646744 |
385 | G>D | No |
ClinGen gnomAD |
|
|
CA378635242 rs201470381 |
386 | R>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA5732330 rs201470381 |
386 | R>Q | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA5732331 rs144412439 |
386 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA215200397 rs866598999 |
387 | E>K | No |
ClinGen Ensembl |
|
|
rs1162481041 CA378635154 |
390 | L>R | No |
ClinGen TOPMed |
|
|
rs1327378582 CA378635131 |
392 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA378635088 rs1589977871 |
394 | Q>* | No |
ClinGen Ensembl |
|
|
rs1564759190 CA378635080 |
394 | Q>L | No |
ClinGen Ensembl |
|
|
CA378635068 rs1270420355 |
395 | F>I | No |
ClinGen TOPMed |
|
|
rs570702833 CA5732325 |
396 | V>M | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs767194600 CA5732324 |
398 | Q>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs375547613 CA5732323 |
399 | E>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 399 | E>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1418356949 CA378634953 |
400 | Y>C | No |
ClinGen Ensembl |
|
|
CA215200391 rs539111465 |
402 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA5732321 rs150240288 |
403 | R>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA5732320 rs150240288 |
403 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs140548347 CA5732322 |
403 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA378634876 rs1415035157 |
405 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs760398201 COSM243836 CA5732318 |
406 | R>C | Variant assessed as Somatic; 0.0 impact. prostate [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA378634870 rs760398201 |
406 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378634862 rs1453578509 |
406 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA5732316 rs772000176 |
408 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA378634826 rs1259673040 |
409 | H>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA378634801 rs1314526783 |
410 | L>Q | No |
ClinGen gnomAD |
|
|
CA5732313 rs769737772 |
412 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
rs746015077 CA5732312 |
414 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs781558861 CA5732311 |
414 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs139425659 COSM291544 CA5732307 |
415 | R>Q | large_intestine [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
COSM1346541 rs778302866 CA5732309 |
415 | R>W | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs966833897 CA215200381 |
416 | I>V | No |
ClinGen Ensembl |
|
|
CA378634720 rs1355213772 |
417 | H>R | No |
ClinGen TOPMed |
|
|
rs199611205 CA5732305 |
418 | V>I | No |
ClinGen ExAC TOPMed |
|
|
CA378634698 rs1171718267 |
420 | P>L | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 421 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs758966246 CA5732304 |
422 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA378634665 rs1390610140 |
423 | N>K | No |
ClinGen TOPMed gnomAD |
|
|
rs1564759063 CA378634661 |
424 | P>S | No |
ClinGen Ensembl |
|
|
rs367761553 CA5732302 |
425 | D>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA378634650 rs367761553 |
425 | D>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5732301 rs367761553 |
425 | D>Y | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs771729647 CA378634613 |
427 | Y>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs772955437 CA5732300 |
427 | Y>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1603110 rs761713000 CA5732298 |
428 | E>K | liver [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs774140430 CA5732296 |
430 | A>G | No |
ClinGen ExAC gnomAD |
|
|
rs1219725 CA378634541 |
431 | Y>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA5732293 rs745908668 |
432 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732272 rs773304465 |
434 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA5732271 rs748507520 |
435 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751135616 CA215200069 CA215200067 |
436 | E>D | No |
ClinGen gnomAD |
|
|
rs1472634419 CA378634208 |
441 | S>F | No |
ClinGen gnomAD |
|
|
CA5732269 rs779359925 |
443 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1200559599 CA378634159 |
443 | G>V | No |
ClinGen TOPMed |
|
|
CA215200062 rs200985867 |
444 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
CA378634142 rs1268544607 |
444 | R>H | No |
ClinGen TOPMed gnomAD |
|
|
CA378634135 rs1268544607 |
444 | R>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1427004840 CA378634128 |
445 | W>R | No |
ClinGen TOPMed |
|
|
rs749767431 CA5732266 |
450 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA378633973 rs1209526349 |
453 | N>I | No |
ClinGen gnomAD |
|
|
CA5732265 rs62640897 |
454 | N>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1335068677 CA378633928 |
456 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
CA378633904 rs1442844058 |
457 | P>L | No |
ClinGen gnomAD |
|
|
rs1368427272 CA378633866 |
460 | N>D | No |
ClinGen gnomAD |
|
|
CA378633855 rs1457397300 |
460 | N>K | No |
ClinGen gnomAD |
|
|
rs373921701 COSM3790565 CA5732262 |
460 | N>S | Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs369814117 CA5732261 |
461 | T>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1386559446 CA378633850 |
461 | T>S | No |
ClinGen gnomAD |
|
|
rs763980028 CA5732259 |
462 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs765333652 CA215200055 |
468 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs765333652 CA5732256 |
468 | D>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732255 rs138440648 |
469 | R>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs138440648 CA5732254 |
469 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs200819708 CA5732253 |
469 | R>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA378633449 rs201420520 |
470 | Q>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs201420520 CA5732252 |
470 | Q>E | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1345732651 CA378633432 |
472 | V>D | No |
ClinGen TOPMed gnomAD |
|
|
rs200663265 CA215200045 |
478 | N>D | No |
ClinGen TOPMed gnomAD |
|
|
rs200663265 CA215200047 |
478 | N>H | No |
ClinGen TOPMed gnomAD |
|
|
rs954690841 CA215200044 |
478 | N>S | No |
ClinGen Ensembl |
|
|
rs140728421 CA5732250 |
480 | Y>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs749707890 CA5732249 |
481 | I>M | No |
ClinGen ExAC gnomAD |
|
|
rs1435411422 CA378633363 |
483 | I>V | No |
ClinGen gnomAD |
|
|
CA378633357 rs1263879435 |
484 | P>T | No |
ClinGen TOPMed |
|
|
CA5732248 rs780532016 |
486 | W>C | No |
ClinGen ExAC gnomAD |
|
|
rs1315680477 CA378633343 |
486 | W>R | No |
ClinGen gnomAD |
|
| TCGA novel | 487 | F>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs770288035 CA5732247 |
489 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378633307 rs1394911042 |
491 | N>D | No |
ClinGen gnomAD |
|
|
CA5732244 rs199507480 |
491 | N>K | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA5732245 rs780774935 |
491 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378633298 rs1433819019 |
492 | A>V | No |
ClinGen Ensembl |
|
| TCGA novel | 493 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA5732243 rs143241838 |
493 | T>M | Variant assessed as Somatic; 0.0001386 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA378633293 rs143241838 |
493 | T>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1230913235 CA378632602 |
494 | V>L | No |
ClinGen gnomAD |
|
|
rs1589970803 CA378632598 |
495 | A>P | No |
ClinGen Ensembl |
|
|
rs753796864 CA5732218 |
496 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA5732216 rs200207468 |
497 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA215199195 rs554307813 |
501 | V>I | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA378632550 rs1406239300 |
502 | I>M | No |
ClinGen gnomAD |
|
|
CA215199193 rs987912217 |
505 | M>I | No |
ClinGen TOPMed |
|
|
CA5732215 rs751593437 |
505 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732213 rs764241273 |
509 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs898514605 CA215199190 |
510 | F>C | No |
ClinGen TOPMed gnomAD |
|
|
rs1231005915 CA378632489 |
511 | V>A | No |
ClinGen gnomAD |
|
|
CA5732212 rs763182723 |
511 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1468690860 CA378632480 |
513 | G>C | No |
ClinGen TOPMed gnomAD |
|
|
CA215199186 rs1016902997 |
513 | G>D | No |
ClinGen Ensembl |
|
|
CA5732209 rs759866479 |
514 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1333547797 CA378632475 |
514 | G>V | No |
ClinGen gnomAD |
|
|
rs1284317153 CA378632464 |
516 | L>M | No |
ClinGen gnomAD |
|
|
rs1404276251 CA378632459 |
517 | Q>* | No |
ClinGen gnomAD |
|
|
CA5732208 rs377424380 |
517 | Q>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs377424380 CA5732207 |
517 | Q>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs772873539 CA5732205 |
519 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378632439 rs1373560626 |
520 | E>G | No |
ClinGen gnomAD |
|
|
CA5732202 rs1374701771 |
520 | E>K | No |
ClinGen TOPMed |
|
|
rs1374701771 CA378632442 |
520 | E>Q | No |
ClinGen TOPMed |
|
|
rs778760709 CA5732200 |
522 | V>L | No |
ClinGen ExAC gnomAD |
|
|
rs1161342087 CA378632425 |
523 | V>M | No |
ClinGen gnomAD |
|
|
rs754793118 CA5732199 |
524 | A>S | No |
ClinGen ExAC gnomAD |
|
|
rs973544102 CA215199177 |
524 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA378632409 rs10794567 |
525 | Y>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 525 | Y>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs756015936 CA5732196 |
526 | P>T | No |
ClinGen ExAC gnomAD |
|
|
CA5732195 rs751586759 |
527 | Y>D | No |
ClinGen ExAC gnomAD |
|
|
rs1217291885 CA378632395 COSM268382 |
528 | D>N | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
rs1284186247 CA378632386 |
529 | L>V | No |
ClinGen gnomAD |
|
|
CA5732192 rs752893237 |
530 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs201710320 CA5732190 |
531 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA5732189 rs201710320 |
531 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs765435589 COSM915773 CA5732191 |
531 | R>W | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA5732188 rs766862013 |
532 | S>F | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 532 | S>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378632355 rs766862013 |
532 | S>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 533 | P>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs761120564 CA5732187 |
533 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs376940141 COSM1504711 CA5732186 |
534 | W>* | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs181886504 COSM537673 CA5732185 |
536 | T>M | lung pancreas [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD |
| TCGA novel | 537 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs768195340 CA5732182 |
538 | E>A | No |
ClinGen ExAC gnomAD |
|
|
rs147621142 CA215199164 |
538 | E>D | No |
ClinGen ESP TOPMed |
|
|
rs1435229189 CA378632217 |
539 | H>P | No |
ClinGen gnomAD |
|
|
CA378632219 rs1435229189 |
539 | H>R | No |
ClinGen gnomAD |
|
|
rs749050997 CA5732181 |
540 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749050997 CA378632207 |
540 | T>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732180 rs779733716 |
541 | P>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378632140 rs1419796814 |
542 | T>I | No |
ClinGen gnomAD |
|
|
rs1589970370 CA378632160 |
542 | T>P | No |
ClinGen Ensembl |
|
|
rs781155643 CA5732177 |
543 | P>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA5732178 rs145279129 |
543 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA378632097 rs10794566 |
544 | D>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA5732175 rs752778704 |
544 | D>N | No |
ClinGen ExAC gnomAD |
|
|
COSM3382718 rs1278707606 CA378632090 |
545 | D>N | pancreas [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA5732173 rs754192732 |
546 | H>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs754192732 CA5732172 |
546 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378632062 rs1475877032 |
546 | H>Y | No |
ClinGen TOPMed |
|
|
rs1298010139 CA378632045 |
547 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs761174266 CA5732170 |
548 | F>S | No |
ClinGen ExAC gnomAD |
|
|
rs150707293 CA5732168 |
549 | R>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA5732167 rs774008546 |
549 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732166 COSM1675632 rs774008546 |
549 | R>L | lung [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs768303221 CA5732165 |
550 | W>* | No |
ClinGen ExAC gnomAD |
|
|
CA378631989 rs1394826112 |
550 | W>R | No |
ClinGen TOPMed |
|
|
rs369779958 CA5732164 |
551 | L>Q | No |
ClinGen ESP ExAC gnomAD |
|
| TCGA novel | 552 | A>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1334039190 CA378631952 |
552 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs775246800 CA5732163 |
552 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1589970220 CA378631929 |
553 | Y>H | No |
ClinGen Ensembl |
|
|
rs769452613 CA5732162 |
554 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA5732160 rs770868672 |
555 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs770868672 CA5732159 |
555 | Y>F | No |
ClinGen ExAC gnomAD |
|
|
rs776419928 CA215199148 |
555 | Y>H | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 556 | A>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378631800 rs748178531 |
559 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
CA378631808 rs1286752769 |
559 | H>R | No |
ClinGen TOPMed |
|
|
COSM1603108 CA5732157 rs778892334 |
560 | R>C | Variant assessed as Somatic; 0.0 impact. liver breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs559678940 CA215199141 |
560 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes NCI-TCGA TOPMed gnomAD |
| TCGA novel | 562 | M>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1253418408 CA378631721 |
563 | T>R | No |
ClinGen gnomAD |
|
|
rs547897756 CA378631701 |
564 | D>E | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1344711604 CA378631687 |
565 | A>D | No |
ClinGen gnomAD |
|
|
CA5732155 COSM310316 rs753988266 |
565 | A>T | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA5732153 rs529727115 |
566 | R>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA5732154 rs780378275 |
566 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 567 | R>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1235223071 CA378631656 |
568 | R>G | No |
ClinGen gnomAD |
|
|
CA5732152 rs750826613 |
568 | R>T | No |
ClinGen ExAC gnomAD |
|
|
rs1235223071 CA378631653 |
568 | R>W | No |
ClinGen gnomAD |
|
|
CA378631631 rs1589970090 |
569 | V>G | No |
ClinGen Ensembl |
|
| TCGA novel | 569 | V>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs943461132 CA215199137 |
570 | C>W | No |
ClinGen TOPMed |
|
|
rs1250346217 CA378631608 |
571 | H>Y | No |
ClinGen TOPMed |
|
|
CA5732151 rs768083943 |
572 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751042921 CA5732149 |
573 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs1399087173 CA378631509 |
576 | Q>K | No |
ClinGen gnomAD |
|
|
RCV000947297 rs112981683 CA5732147 |
577 | K>R | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA378631458 rs1462570090 |
578 | E>G | No |
ClinGen gnomAD |
|
|
rs148621668 CA5732145 |
581 | T>A | No |
ClinGen ESP ExAC gnomAD |
|
|
rs375460068 CA5732144 |
583 | N>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs145963968 CA5732142 |
585 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1376579257 CA378631343 |
585 | A>V | No |
ClinGen TOPMed |
|
|
CA5732141 COSM225661 rs746915657 |
586 | S>F | NS [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA378631329 rs1215735321 |
587 | W>* | No |
ClinGen gnomAD |
|
|
rs576715653 CA378631311 |
588 | H>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA378631309 rs1372623227 |
589 | T>P | No |
ClinGen TOPMed |
|
|
CA215199126 rs373117160 |
590 | V>A | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA5732138 rs749448782 |
590 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs564623475 CA5732136 |
591 | A>P | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs564623475 COSM260278 CA5732137 |
591 | A>T | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA gnomAD |
|
CA5732134 rs142483883 |
592 | G>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA378631276 rs142483883 |
592 | G>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA5732135 rs750771582 |
592 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs774473278 TCGA novel CA5732102 |
593 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC gnomAD NCI-TCGA |
| TCGA novel | 594 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1345403559 CA378630502 |
594 | L>P | No |
ClinGen gnomAD |
|
|
rs944271451 CA215198311 |
596 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1589964823 CA378630428 |
599 | Y>* | No |
ClinGen Ensembl |
|
|
CA378630417 rs1253983492 |
600 | L>P | No |
ClinGen TOPMed |
|
|
CA5732100 rs746005645 |
601 | H>P | No |
ClinGen ExAC gnomAD |
|
|
CA378630398 rs1292795012 |
602 | T>A | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA215198310 rs978313657 |
604 | C>W | No |
ClinGen TOPMed gnomAD |
|
|
CA5732099 rs776991159 |
604 | C>Y | No |
ClinGen ExAC gnomAD |
|
|
CA5732097 rs747279699 |
606 | E>K | Variant assessed as Somatic; 4.62e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA5732095 rs758729644 |
608 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs779452046 CA5732093 |
609 | I>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs748664773 CA5732094 |
609 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA5732092 rs561902091 COSM1675631 |
610 | Y>C | ovary [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA215198308 rs764523007 |
610 | Y>H | No |
ClinGen Ensembl |
|
|
CA5732090 rs115379653 |
611 | V>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA378630288 rs115379653 |
611 | V>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs755816823 CA5732089 |
613 | C>Y | No |
ClinGen ExAC gnomAD |
|
|
CA378630238 rs1277618132 |
615 | K>E | No |
ClinGen gnomAD |
|
|
CA378630205 rs1196066993 |
617 | P>S | No |
ClinGen gnomAD |
|
|
CA5732088 rs750148969 |
618 | H>L | No |
ClinGen ExAC gnomAD |
|
|
rs767315657 CA5732087 |
618 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
rs750148969 CA378630191 |
618 | H>R | No |
ClinGen ExAC gnomAD |
|
|
CA378630184 rs1355476857 |
619 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
rs1413429385 CA378630159 |
620 | S>N | No |
ClinGen gnomAD |
|
|
rs1340285912 CA378630140 |
622 | L>M | No |
ClinGen gnomAD |
|
|
rs145812368 CA5732085 COSM1346538 |
624 | E>K | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA5732083 rs537047960 |
626 | W>* | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs537047960 CA5732082 |
626 | W>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA5732084 rs764195020 |
626 | W>R | No |
ClinGen ExAC gnomAD |
|
|
rs1420064685 CA378630102 |
627 | E>D | No |
ClinGen gnomAD |
|
|
rs772474255 CA5732080 |
630 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs772474255 CA5732079 |
630 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1492179 CA5732081 rs368753397 |
630 | R>W | kidney Variant assessed as Somatic; 4.619e-05 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1236744111 CA378630060 |
634 | I>N | No |
ClinGen gnomAD |
|
|
rs78179127 CA5732077 |
635 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
| TCGA novel | 636 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378630037 CA5732076 rs779323414 |
637 | M>I | No |
ClinGen ExAC gnomAD |
|
|
CA5732057 rs530115758 |
640 | V>F | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs530115758 CA5732058 |
640 | V>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs780477883 CA5732055 |
642 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs780477883 CA5732056 |
642 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs769337470 CA5732054 |
642 | R>H | Variant assessed as Somatic; 4.62e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs138945308 CA5732052 |
643 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs892035626 CA215198017 |
643 | G>R | No |
ClinGen Ensembl |
|
|
rs138945308 CA5732053 |
643 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1176488435 CA378629549 |
646 | G>D | No |
ClinGen gnomAD |
|
| TCGA novel | 650 | D>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA5732050 rs751352280 |
650 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs1318926349 CA378629444 |
652 | H>R | No |
ClinGen gnomAD |
|
|
rs562507770 CA5732049 |
655 | G>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 657 | P>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs142684083 CA5732047 |
658 | N>K | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs997705127 CA215198016 |
659 | A>T | No |
ClinGen gnomAD |
|
|
CA5732046 rs765152743 |
659 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA5732045 rs756148801 |
660 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA215198015 rs901974839 |
661 | I>M | No |
ClinGen Ensembl |
|
|
CA5732044 rs140927371 |
662 | S>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA5732043 rs138679076 |
663 | V>I | Variant assessed as Somatic; 4.62e-05 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs764423566 CA5732040 |
665 | G>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764423566 CA5732042 |
665 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 665 | G>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs764423566 CA5732041 |
665 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5732038 COSM1249080 rs770208711 |
667 | N>K | oesophagus [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs745327315 CA5732036 |
668 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs147055269 CA5732034 |
671 | R>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs746636608 CA5732033 |
671 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA378629131 rs1341668899 |
672 | T>I | No |
ClinGen TOPMed |
|
|
CA378628278 rs1172009212 |
674 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
CA378628280 rs1172009212 |
674 | N>T | No |
ClinGen TOPMed gnomAD |
|
|
rs746583159 CA5732013 |
674 | N>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1342470209 CA378628266 |
675 | D>G | No |
ClinGen TOPMed |
|
|
rs747926025 CA5732011 |
675 | D>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs747926025 CA5732010 |
675 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs754838132 CA5732008 |
677 | D>V | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 679 | W>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA5732006 rs749163201 COSM3414786 |
680 | R>C | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
COSM3396970 CA5732005 rs780028739 |
680 | R>H | Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs1481124044 CA378628187 |
681 | L>F | No |
ClinGen gnomAD |
|
|
rs1234839677 CA378628186 |
681 | L>P | No |
ClinGen gnomAD |
|
|
rs757327939 CA5732004 |
683 | N>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378628161 rs1317421303 |
683 | N>K | No |
ClinGen gnomAD |
|
|
rs1273870238 CA378628152 |
684 | P>R | No |
ClinGen gnomAD |
|
|
rs867049659 CA215197151 |
684 | P>S | No |
ClinGen Ensembl |
|
| TCGA novel | 688 | V>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1323428914 CA378628106 |
688 | V>M | No |
ClinGen gnomAD |
|
|
rs940829569 CA215197150 |
691 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs758572547 CA5732001 |
692 | K>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1373724245 CA378628056 |
692 | K>R | No |
ClinGen gnomAD |
|
|
CA378628041 rs1398980589 COSM388946 |
694 | E>D | lung [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs770522746 COSM3665569 CA5731998 |
694 | E>K | Variant assessed as Somatic; 0.0 impact. liver [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA378628034 rs1325976479 |
695 | G>V | No |
ClinGen gnomAD |
|
|
CA378628024 rs1367238015 |
697 | T>A | No |
ClinGen gnomAD |
|
|
rs1366789123 CA378628020 |
697 | T>I | No |
ClinGen TOPMed |
|
|
rs1367238015 CA378628025 |
697 | T>P | No |
ClinGen gnomAD |
|
|
rs1158332407 CA378628009 |
699 | S>F | No |
ClinGen gnomAD |
|
|
rs921233363 CA215197148 |
699 | S>T | No |
ClinGen TOPMed |
|
|
CA5731996 rs561186270 |
700 | T>A | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 701 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1564746967 CA378627973 |
704 | M>I | No |
ClinGen Ensembl |
|
|
CA378627969 rs1177063432 |
705 | V>L | No |
ClinGen gnomAD |
|
|
rs771808249 COSM386322 CA5731992 |
709 | M>I | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA5731993 rs772867825 |
709 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA5731991 rs761337276 |
710 | G>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA378627935 rs1319667985 |
710 | G>R | No |
ClinGen TOPMed |
|
|
CA378627930 rs1310223043 |
711 | A>S | No |
ClinGen TOPMed |
|
|
CA378627928 rs1310223043 |
711 | A>T | No |
ClinGen TOPMed |
|
|
rs774098993 CA5731990 |
711 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA378627920 rs1263634298 |
712 | T>I | No |
ClinGen gnomAD |
|
|
CA5731989 rs768326532 |
713 | R>G | No |
ClinGen ExAC gnomAD |
|
|
rs749176185 CA5731988 |
713 | R>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1039725030 CA215197147 |
714 | C>* | No |
ClinGen TOPMed |
|
|
rs779902262 CA5731987 |
714 | C>G | No |
ClinGen ExAC |
|
|
rs1311151376 CA378627912 |
714 | C>Y | No |
ClinGen gnomAD |
|
| TCGA novel | 717 | T>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs747043833 CA5731985 |
718 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA5731984 rs777862494 |
719 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA5731983 rs148889875 |
719 | S>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 721 | T>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA5731982 CA5731981 rs779261757 |
723 | M>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1247799371 CA378627841 |
724 | A>G | No |
ClinGen TOPMed |
|
|
rs1454746251 CA378627824 |
727 | R>* | No |
ClinGen gnomAD |
|
|
COSM236396 CA5731980 rs755228564 |
727 | R>Q | autonomic_ganglia [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
COSM173144 rs967577808 CA215197146 |
728 | E>D | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated Ensembl NCI-TCGA |
|
rs754267131 CA5731979 |
729 | I>F | No |
ClinGen ExAC gnomAD |
|
|
CA5731978 rs766940993 |
730 | M>V | No |
ClinGen ExAC |
|
|
CA5731977 rs761292953 |
732 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1395937454 CA378627784 |
733 | F>L | No |
ClinGen gnomAD |
|
|
CA5731974 rs761447450 |
738 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA5731973 rs62640887 |
741 | P>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1486145785 CA378627714 |
743 | R>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1209217195 CA378627717 |
743 | R>T | No |
ClinGen gnomAD |
|
|
CA5731969 rs149753704 |
744 | R>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA5731970 rs149753704 COSM74253 |
744 | R>Q | ovary [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
rs762600262 CA5731971 |
744 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA5731968 rs745775195 |
747 | L>R | No |
ClinGen ExAC gnomAD |
|
|
CA378627692 rs374183184 |
748 | R>L | No |
ClinGen ESP ExAC TOPMed |
|
|
rs374183184 CA215197143 |
748 | R>P | No |
ClinGen ESP ExAC TOPMed |
|
|
CA5731966 rs374183184 |
748 | R>Q | No |
ClinGen ESP ExAC TOPMed |
|
|
rs1455207884 CA378627693 COSM915768 |
748 | R>W | pancreas Variant assessed as Somatic; impact. endometrium [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
rs139450310 CA5731964 |
750 | Q>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs139450310 CA5731965 |
750 | Q>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs7088479 CA378627683 |
750 | Q>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs7088479 CA378627684 |
750 | Q>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs7088479 VAR_048603 CA5731963 |
750 | Q>R | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA5731961 rs755249876 |
753 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA5731960 rs749626733 |
753 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs780530593 CA5731959 |
754 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
COSM2021054 CA5731958 rs756593635 |
755 | R>C | Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs750948954 CA5731957 |
755 | R>H | Variant assessed as Somatic; 4.627e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
| rs1464713173 | 757 | G>= | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA378627645 rs1589953625 |
757 | G>G | No |
ClinGen Ensembl |
|
|
CA378627642 rs1464713173 |
757 | G>S | No |
ClinGen TOPMed gnomAD |
No associated diseases with Q8N436
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular space | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metallocarboxypeptidase activity | Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. |
| zinc ion binding | Binding to a zinc ion (Zn). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| peptide metabolic process | The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. |
| protein processing | Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein. |
16 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P04836 | CPE | Carboxypeptidase E | Bos taurus (Bovine) | PR |
| Q2KJ83 | CPN1 | Carboxypeptidase N catalytic chain | Bos taurus (Bovine) | PR |
| Q8QGP3 | CPZ | Carboxypeptidase Z | Gallus gallus (Chicken) | PR |
| P14384 | CPM | Carboxypeptidase M | Homo sapiens (Human) | PR |
| Q96SM3 | CPXM1 | Probable carboxypeptidase X1 | Homo sapiens (Human) | PR |
| Q66K79 | CPZ | Carboxypeptidase Z | Homo sapiens (Human) | PR |
| Q8IUX7 | AEBP1 | Adipocyte enhancer-binding protein 1 | Homo sapiens (Human) | PR |
| O75976 | CPD | Carboxypeptidase D | Homo sapiens (Human) | PR |
| Q80V42 | Cpm | Carboxypeptidase M | Mus musculus (Mouse) | PR |
| O89001 | Cpd | Carboxypeptidase D | Mus musculus (Mouse) | PR |
| Q9JJN5 | Cpn1 | Carboxypeptidase N catalytic chain | Mus musculus (Mouse) | PR |
| Q9Z100 | Cpxm1 | Probable carboxypeptidase X1 | Mus musculus (Mouse) | PR |
| Q640N1 | Aebp1 | Adipocyte enhancer-binding protein 1 | Mus musculus (Mouse) | PR |
| Q9D2L5 | Cpxm2 | Inactive carboxypeptidase-like protein X2 | Mus musculus (Mouse) | PR |
| Q9EQV8 | Cpn1 | Carboxypeptidase N catalytic chain | Rattus norvegicus (Rat) | PR |
| A2RUV9 | Aebp1 | Adipocyte enhancer-binding protein 1 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSRPGTATPA | LALVLLAVTL | AGVGAQGAAL | EDPDYYGQEI | WSREPYYARP | EPELETFSPP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LPAGPGEEWE | RRPQEPRPPK | RATKPKKAPK | REKSAPEPPP | PGKHSNKKVM | RTKSSEKAAN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DDHSVRVARE | DVRESCPPLG | LETLKITDFQ | LHASTVKRYG | LGAHRGRLNI | QAGINENDFY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DGAWCAGRND | LQQWIEVDAR | RLTRFTGVIT | QGRNSLWLSD | WVTSYKVMVS | NDSHTWVTVK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NGSGDMIFEG | NSEKEIPVLN | ELPVPMVARY | IRINPQSWFD | NGSICMRMEI | LGCPLPDPNN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YYHRRNEMTT | TDDLDFKHHN | YKEMRQLMKV | VNEMCPNITR | IYNIGKSHQG | LKLYAVEISD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HPGEHEVGEP | EFHYIAGAHG | NEVLGRELLL | LLVQFVCQEY | LARNARIVHL | VEETRIHVLP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SLNPDGYEKA | YEGGSELGGW | SLGRWTHDGI | DINNNFPDLN | TLLWEAEDRQ | NVPRKVPNHY |
| 490 | 500 | 510 | 520 | 530 | 540 |
| IAIPEWFLSE | NATVAAETRA | VIAWMEKIPF | VLGGNLQGGE | LVVAYPYDLV | RSPWKTQEHT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| PTPDDHVFRW | LAYSYASTHR | LMTDARRRVC | HTEDFQKEEG | TVNGASWHTV | AGSLNDFSYL |
| 610 | 620 | 630 | 640 | 650 | 660 |
| HTNCFELSIY | VGCDKYPHES | QLPEEWENNR | ESLIVFMEQV | HRGIKGLVRD | SHGKGIPNAI |
| 670 | 680 | 690 | 700 | 710 | 720 |
| ISVEGINHDI | RTANDGDYWR | LLNPGEYVVT | AKAEGFTAST | KNCMVGYDMG | ATRCDFTLSK |
| 730 | 740 | 750 | |||
| TNMARIREIM | EKFGKQPVSL | PARRLKLRGQ | KRRQRG |