Q32Q06
Gene name |
Ap1m1 |
Protein name |
AP-1 complex subunit mu-1 |
Names |
AP-mu chain family member mu1A, Adaptor protein complex AP-1 subunit mu-1, Adaptor-related protein complex 1 subunit mu-1, Clathrin assembly protein complex 1 mu-1 medium chain 1, Golgi adaptor HA1/AP1 adaptin mu-1 subunit, Mu-adaptin 1, Mu1A-adaptin |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:306332 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q32Q06
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q32Q06-F1 | Predicted | AlphaFoldDB |
No variants for Q32Q06
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q32Q06 | |||||
No associated diseases with Q32Q06
1 regional properties for Q32Q06
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, GATA-type | 187 - 249 | IPR000679 |
Functions
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| clathrin adaptor complex | A membrane coat adaptor complex that links clathrin to a membrane. |
| clathrin-coated vesicle | A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes. |
| clathrin-coated vesicle membrane | The lipid bilayer surrounding a clathrin-coated vesicle. |
| cytoplasmic vesicle | A vesicle found in the cytoplasm of a cell. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| clathrin adaptor activity | Bringing together a cargo protein with clathrin, responsible for the formation of endocytic vesicles. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| endosome to melanosome transport | The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle. |
| intracellular protein transport | The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. |
| melanosome organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. |
| vesicle-mediated transport | A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q00776 | APM1 | AP-1 complex subunit mu-1-I | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q2KJ81 | AP1M1 | AP-1 complex subunit mu-1 | Bos taurus (Bovine) | PR |
| Q3SYW1 | AP1M2 | AP-1 complex subunit mu-2 | Bos taurus (Bovine) | PR |
| Q9Y6Q5 | AP1M2 | AP-1 complex subunit mu-2 | Homo sapiens (Human) | PR |
| Q9BXS5 | AP1M1 | AP-1 complex subunit mu-1 | Homo sapiens (Human) | PR |
| Q9WVP1 | Ap1m2 | AP-1 complex subunit mu-2 | Mus musculus (Mouse) | PR |
| P35585 | Ap1m1 | AP-1 complex subunit mu-1 | Mus musculus (Mouse) | PR |
| Q9SB50 | AP4M | AP-4 complex subunit mu | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O22715 | AP1M2 | AP-1 complex subunit mu-2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SAC9 | AP1M1 | AP-1 complex subunit mu-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSASAVYVLD | LKGKVLICRN | YRGDVDMSEV | EHFMPILMEK | EEEGMLSPIL | AHGGVRFMWI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KHNNLYLVAT | SKKNACVSLV | FSFLYKVVQV | FSEYFKELEE | ESIRDNFVII | YELLDELMDF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GYPQTTDSKI | LQEYITQEGH | KLETGAPRPP | ATVTNAVSWR | SEGIKYRKNE | VFLDVIEAVN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LLVSANGNVL | RSEIVGSIKM | RVFLSGMPEL | RLGLNDKVLF | DNTGRGKSKS | VELEDVKFHQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CVRLSRFEND | RTISFIPPDG | EFELMSYRLN | THVKPLIWIE | SVIEKHSHSR | IEYMVKAKSQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FKRRSTANNV | EIHIPVPNDA | DSPKFKTTVG | SVKWVPENSE | IVWSIKSFPG | GKEYLMRAHF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GLPSVEAEDK | EGKPPISVKF | EIPYFTTSGI | QVRYLKIIEK | SGYQALPWVR | YITQNGDYQL |
| RTQ |