Q9XIE3
PR
Gene name |
HSP17.6A (At1g59860, F23H11.18) |
Protein name |
17.6 kDa class I heat shock protein 1 |
Names |
17.6 kDa heat shock protein 1, AtHsp17.6A |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G59860 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9XIE3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9XIE3-F1 | Predicted | AlphaFoldDB |
49 variants for Q9XIE3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH05003678 | 4 | I>N | No | 1000Genomes | |
| ENSVATH05003678 | 4 | I>S | No | 1000Genomes | |
| tmp_1_22031486_C_T | 5 | P>S | No | 1000Genomes | |
| ENSVATH05003679 | 8 | F>L | No | 1000Genomes | |
| tmp_1_22031496_T_A | 8 | F>Y | No | 1000Genomes | |
| ENSVATH14361324 | 13 | R>P | No | 1000Genomes | |
| tmp_1_22031524_C_G | 17 | N>K | No | 1000Genomes | |
| ENSVATH05003681 | 20 | D>H | No | 1000Genomes | |
| ENSVATH05003682 | 34 | Q>L | No | 1000Genomes | |
| tmp_1_22031578_C_G | 35 | F>L | No | 1000Genomes | |
| ENSVATH14361336 | 35 | F>Y | No | 1000Genomes | |
| ENSVATH01405798 | 37 | S>L | No | 1000Genomes | |
| ENSVATH05003683 | 37 | S>P | No | 1000Genomes | |
| ENSVATH13653839 | 38 | S>P | No | 1000Genomes | |
| ENSVATH01405799 | 43 | I>M | No | 1000Genomes | |
| ENSVATH01405800 | 44 | A>V | No | 1000Genomes | |
| ENSVATH01405801 | 46 | A>T | No | 1000Genomes | |
| ENSVATH14361337 | 46 | A>V | No | 1000Genomes | |
| ENSVATH05003684 | 48 | V>M | No | 1000Genomes | |
| tmp_1_22031618_G_T | 49 | D>Y | No | 1000Genomes | |
| tmp_1_22031626_A_T | 51 | K>N | No | 1000Genomes | |
| tmp_1_22031636_G_T | 55 | E>* | No | 1000Genomes | |
| ENSVATH01405802 | 56 | A>S | No | 1000Genomes | |
| ENSVATH14361338 | 57 | H>Y | No | 1000Genomes | |
| tmp_1_22031648_T_C | 59 | F>L | No | 1000Genomes | |
| ENSVATH01405803 | 60 | K>N | No | 1000Genomes | |
| tmp_1_22031702_G_T | 77 | D>Y | No | 1000Genomes | |
| ENSVATH13653840 | 81 | L>P | No | 1000Genomes | |
| ENSVATH14361340 | 84 | S>T | No | 1000Genomes | |
| ENSVATH05003685 | 87 | R>S | No | 1000Genomes | |
| ENSVATH05003686 | 91 | K>R | No | 1000Genomes | |
| ENSVATH13653841 | 92 | E>* | No | 1000Genomes | |
| ENSVATH05003687 | 92 | E>D | No | 1000Genomes | |
| ENSVATH01405806 | 93 | E>D | No | 1000Genomes | |
| ENSVATH13653842 | 96 | D>E | No | 1000Genomes | |
| tmp_1_22031767_G_T | 98 | W>C | No | 1000Genomes | |
| ENSVATH05003688 | 100 | R>G | No | 1000Genomes | |
| ENSVATH01405807 | 100 | R>H | No | 1000Genomes | |
| ENSVATH05003690 | 102 | E>K | No | 1000Genomes | |
| tmp_1_22031790_G_T | 106 | G>V | No | 1000Genomes | |
| tmp_1_22031799_C_T | 109 | S>L | No | 1000Genomes | |
| tmp_1_22031798_T_C | 109 | S>P | No | 1000Genomes | |
| tmp_1_22031817_C_T | 115 | P>L | No | 1000Genomes | |
| ENSVATH05003691 | 121 | D>Y | No | 1000Genomes | |
| tmp_1_22031846_G_C | 125 | A>P | No | 1000Genomes | |
| tmp_1_22031898_A_G | 142 | N>S | No | 1000Genomes | |
| ENSVATH13653865 | 144 | K>M | No | 1000Genomes | |
| ENSVATH14361341 | 147 | Q>K | No | 1000Genomes | |
| ENSVATH05003692 | 152 | D>A | No | 1000Genomes |
No associated diseases with Q9XIE3
No regional properties for Q9XIE3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9XIE3 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein self-association | Binding to a domain within the same polypeptide. |
| unfolded protein binding | Binding to an unfolded protein. |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to hypoxia | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. |
| protein complex oligomerization | The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. |
| protein folding | The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. |
| response to heat | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. |
| response to hydrogen peroxide | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus. |
| response to osmotic stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. |
| response to salt stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P02518 | Hsp27 | Heat shock protein 27 | Drosophila melanogaster (Fruit fly) | PR |
| P02511 | CRYAB | Alpha-crystallin B chain | Homo sapiens (Human) | PR |
| Q9UJY1 | HSPB8 | Heat shock protein beta-8 | Homo sapiens (Human) | PR |
| Q943E7 | HSP16.9C | 16.9 kDa class I heat shock protein 3 | Oryza sativa subsp japonica (Rice) | PR |
| P27777 | HSP16.9A | 16.9 kDa class I heat shock protein 1 | Oryza sativa subsp japonica (Rice) | PR |
| Q943E6 | HSP16.9B | 16.9 kDa class I heat shock protein 2 | Oryza sativa subsp japonica (Rice) | PR |
| Q6K7E9 | HSP18.6 | 18.6 kDa class III heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| Q84Q77 | HSP17.9A | 17.9 kDa class I heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| P31673 | HSP17.4 | 17.4 kDa class I heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| Q84Q72 | HSP18.1 | 18.1 kDa class I heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| Q84J50 | HSP17.7 | 17.7 kDa class I heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| P30236 | HSP22.0 | 22.0 kDa class IV heat shock protein | Glycine max (Soybean) (Glycine hispida) | PR |
| O49710 | HSP15.4 | 15.4 kDa class V heat shock protein | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O64564 | HSP18.5 | 18.5 kDa class IV heat shock protein | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P19037 | HSP18.1 | 18.1 kDa class I heat shock protein | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q38806 | HSP22.0 | 22.0 kDa heat shock protein | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P30221 | 17.8 kDa class I heat shock protein | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSLIPSFFGN | NRRINNNIFD | PFSLDVWDPF | KELQFPSSSS | SAIANARVDW | KETAEAHVFK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ADLPGMKKEE | VKVEIEDDSV | LKISGERHVE | KEEKQDTWHR | VERSSGGFSR | KFRLPENVKM |
| 130 | 140 | 150 | |||
| DQVKASMENG | VLTVTVPKVE | TNKKKAQVKS | IDISG |