O49710
Gene name |
HSP15.4 (At4g21870, T8O5.80) |
Protein name |
15.4 kDa class V heat shock protein |
Names |
15.4 kDa heat shock protein, AtHsp15.4 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G21870 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O49710
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O49710-F1 | Predicted | AlphaFoldDB |
17 variants for O49710
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_4_11604225_T_G | 21 | N>H | No | 1000Genomes | |
| tmp_4_11604217_A_C | 23 | Y>* | No | 1000Genomes | |
| tmp_4_11604215_T_A | 24 | Q>L | No | 1000Genomes | |
| ENSVATH06747588 | 73 | P>L | No | 1000Genomes | |
| ENSVATH06747586 | 77 | L>V | No | 1000Genomes | |
| ENSVATH02903688 | 79 | T>N | No | 1000Genomes | |
| ENSVATH02903688 | 79 | T>S | No | 1000Genomes | |
| tmp_4_11603880_C_T | 94 | G>E | No | 1000Genomes | |
| ENSVATH12125855 | 101 | D>A | No | 1000Genomes | |
| ENSVATH06747584 | 101 | D>N | No | 1000Genomes | |
| ENSVATH02903686 | 107 | I>V | No | 1000Genomes | |
| ENSVATH14275449 | 110 | K>R | No | 1000Genomes | |
| tmp_4_11603820_G_A | 114 | T>I | No | 1000Genomes | |
| ENSVATH06747583 | 114 | T>P | No | 1000Genomes | |
| ENSVATH06747583 | 114 | T>S | No | 1000Genomes | |
| ENSVATH02903683 | 117 | L>F | No | 1000Genomes | |
| tmp_4_11603786_T_G | 125 | E>D | No | 1000Genomes |
No associated diseases with O49710
1 regional properties for O49710
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Alpha crystallin/Hsp20 domain | 19 - 126 | IPR002068 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein self-association | Binding to a domain within the same polypeptide. |
| unfolded protein binding | Binding to an unfolded protein. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| protein complex oligomerization | The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. |
| protein folding | The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. |
| response to heat | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. |
| response to hydrogen peroxide | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus. |
| response to salt stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P02518 | Hsp27 | Heat shock protein 27 | Drosophila melanogaster (Fruit fly) | PR |
| P02511 | CRYAB | Alpha-crystallin B chain | Homo sapiens (Human) | PR |
| Q9UJY1 | HSPB8 | Heat shock protein beta-8 | Homo sapiens (Human) | PR |
| Q943E7 | HSP16.9C | 16.9 kDa class I heat shock protein 3 | Oryza sativa subsp japonica (Rice) | PR |
| P27777 | HSP16.9A | 16.9 kDa class I heat shock protein 1 | Oryza sativa subsp japonica (Rice) | PR |
| Q943E6 | HSP16.9B | 16.9 kDa class I heat shock protein 2 | Oryza sativa subsp japonica (Rice) | PR |
| Q6K7E9 | HSP18.6 | 18.6 kDa class III heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| Q84Q77 | HSP17.9A | 17.9 kDa class I heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| P31673 | HSP17.4 | 17.4 kDa class I heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| Q84Q72 | HSP18.1 | 18.1 kDa class I heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| Q84J50 | HSP17.7 | 17.7 kDa class I heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| P30236 | HSP22.0 | 22.0 kDa class IV heat shock protein | Glycine max (Soybean) (Glycine hispida) | PR |
| O64564 | HSP18.5 | 18.5 kDa class IV heat shock protein | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P19037 | HSP18.1 | 18.1 kDa class I heat shock protein | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q38806 | HSP22.0 | 22.0 kDa heat shock protein | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9XIE3 | HSP17.6A | 17.6 kDa class I heat shock protein 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P30221 | 17.8 kDa class I heat shock protein | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDFQTIQVMP | WEYVLASQSL | NNYQENHVRW | SQSPDSHTFS | VDLPGLRKEE | IKVEIEDSIY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LIIRTEATPM | SPPDQPLKTF | KRKFRLPESI | DMIGISAGYE | DGVLTVIVPK | RIMTRRLIDP |
| 130 | |||||
| SDVPESLQLL | ARAA |