Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q84Q77

Entry ID Method Resolution Chain Position Source
AF-Q84Q77-F1 Predicted AlphaFoldDB

No variants for Q84Q77

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q84Q77

No associated diseases with Q84Q77

2 regional properties for Q84Q77

Type Name Position InterPro Accession
domain ABC1 atypical kinase-like domain 93 - 343 IPR004147
domain UbiB domain, bacteria 93 - 343 IPR045308

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
protein self-association Binding to a domain within the same polypeptide.
unfolded protein binding Binding to an unfolded protein.

5 GO annotations of biological process

Name Definition
protein complex oligomerization The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
response to hydrogen peroxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
response to salt stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.

17 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8MJ36 HSPB8 Heat shock protein beta-8 Canis lupus familiaris (Dog) (Canis familiaris) PR
P02518 Hsp27 Heat shock protein 27 Drosophila melanogaster (Fruit fly) PR
Q9EPX0 Hspb8 Heat shock protein beta-8 Rattus norvegicus (Rat) PR
P27777 HSP16.9A 16.9 kDa class I heat shock protein 1 Oryza sativa subsp japonica (Rice) PR
P31673 HSP17.4 17.4 kDa class I heat shock protein Oryza sativa subsp japonica (Rice) PR
Q6K7E9 HSP18.6 18.6 kDa class III heat shock protein Oryza sativa subsp japonica (Rice) PR
Q84J50 HSP17.7 17.7 kDa class I heat shock protein Oryza sativa subsp japonica (Rice) PR
Q84Q72 HSP18.1 18.1 kDa class I heat shock protein Oryza sativa subsp japonica (Rice) PR
Q943E6 HSP16.9B 16.9 kDa class I heat shock protein 2 Oryza sativa subsp japonica (Rice) PR
Q943E7 HSP16.9C 16.9 kDa class I heat shock protein 3 Oryza sativa subsp japonica (Rice) PR
P30236 HSP22.0 22.0 kDa class IV heat shock protein Glycine max (Soybean) (Glycine hispida) PR
Q9XIE3 HSP17.6A 17.6 kDa class I heat shock protein 1 Arabidopsis thaliana (Mouse-ear cress) PR
O64564 HSP18.5 18.5 kDa class IV heat shock protein Arabidopsis thaliana (Mouse-ear cress) PR
Q38806 HSP22.0 22.0 kDa heat shock protein Arabidopsis thaliana (Mouse-ear cress) PR
O49710 HSP15.4 15.4 kDa class V heat shock protein Arabidopsis thaliana (Mouse-ear cress) PR
P19037 HSP18.1 18.1 kDa class I heat shock protein Arabidopsis thaliana (Mouse-ear cress) PR
P30221 17.8 kDa class I heat shock protein Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MSLIRRSNVF DPFSLDLWDP FDGFPFGSGG SSSGSIFPSF PRGASSETAA FAGARIDWKE
70 80 90 100 110 120
TPEAHVFKAD VPGLKKEEVK VEVDDGNILQ ISGERNKEQE EKTDQWHRVE RSSGKFLRRF
130 140 150 160
RLPDNAKPEQ IKASMENGVL TVTVPKEEAK KPDVKSIQIS G