Q8MJ36
Gene name |
HSPB8 |
Protein name |
Heat shock protein beta-8 |
Names |
HspB8, Protein kinase H11 |
Species |
Canis lupus familiaris (Dog) (Canis familiaris) |
KEGG Pathway |
cfa:403553 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8MJ36
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8MJ36-F1 | Predicted | AlphaFoldDB |
No variants for Q8MJ36
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8MJ36 | |||||
No associated diseases with Q8MJ36
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| chaperone complex | A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein homodimerization activity | Binding to an identical protein to form a homodimer. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to unfolded protein | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus. |
11 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9UJY1 | HSPB8 | Heat shock protein beta-8 | Homo sapiens (Human) | PR |
| Q9JK92 | Hspb8 | Heat shock protein beta-8 | Mus musculus (Mouse) | PR |
| Q9EPX0 | Hspb8 | Heat shock protein beta-8 | Rattus norvegicus (Rat) | PR |
| Q84Q77 | HSP17.9A | 17.9 kDa class I heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| Q84Q72 | HSP18.1 | 18.1 kDa class I heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| Q84J50 | HSP17.7 | 17.7 kDa class I heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| P31673 | HSP17.4 | 17.4 kDa class I heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| Q943E6 | HSP16.9B | 16.9 kDa class I heat shock protein 2 | Oryza sativa subsp japonica (Rice) | PR |
| P27777 | HSP16.9A | 16.9 kDa class I heat shock protein 1 | Oryza sativa subsp japonica (Rice) | PR |
| Q943E7 | HSP16.9C | 16.9 kDa class I heat shock protein 3 | Oryza sativa subsp japonica (Rice) | PR |
| Q6K7E9 | HSP18.6 | 18.6 kDa class III heat shock protein | Oryza sativa subsp japonica (Rice) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MADGQMPFSC | HYPSRLRRDP | FRDSPLPSRL | LDDDFGMDPF | PDDLTSSWRN | WALPRFSTGW |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PGTLRSGMVP | RGPTAAARFG | VPAEGRSPPP | FPGEPWKVCV | NVHSFKPEEL | MVKTKDGYVE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VSGKHEEKQQ | EGGIVSKNFT | KKIQLPAEVD | PVTVFASLSP | EGLLIIEAPQ | VPPYSPFGES |
| 190 | |||||
| NFNNELPQDS | QEVTCT |