AiPD: Autoinhibited Protein Database

Gene name	GALT6
Protein name	Hydroxyproline O-galactosyltransferase GALT6
Names	Beta-1,3-galactosyltransferase 19
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT5G62620
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-351 (Predicted disordered autoinhibitory region) PR

1-351 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9LV16-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
tmp_5_25137140_G_A	2	R>K	No	1000Genomes
ENSVATH00748175	17	I>M	No	1000Genomes
ENSVATH12908311	92	Q>K	No	1000Genomes
ENSVATH14645727	108	S>Y	No	1000Genomes
tmp_5_25137569_A_G	145	E>G	No	1000Genomes
tmp_5_25137644_C_T	170	S>L	No	1000Genomes
tmp_5_25137696_T_A	187	N>K	No	1000Genomes
tmp_5_25137758_G_A	208	R>Q	No	1000Genomes
tmp_5_25137998_G_T	288	R>I	No	1000Genomes
ENSVATH12908314	324	W>C	No	1000Genomes
ENSVATH03465231	338	V>I	No	1000Genomes
ENSVATH07468587	346	V>A	No	1000Genomes
ENSVATH12908335	356	A>T	No	1000Genomes
tmp_5_25138333_C_G	369	H>D	No	1000Genomes
tmp_5_25138493_C_A	388	T>N	No	1000Genomes
tmp_5_25138495_A_G	389	I>V	No	1000Genomes
tmp_5_25138585_T_C	419	S>P	No	1000Genomes
ENSVATH07468589	449	M>I	No	1000Genomes
ENSVATH03465233	451	V>A	No	1000Genomes
tmp_5_25138708_C_T	460	L>F	No	1000Genomes
tmp_5_25138979_C_G	514	C>W	No	1000Genomes
ENSVATH07468592	515	E>G	No	1000Genomes
tmp_5_25138980_G_A	515	E>K	No	1000Genomes
ENSVATH03465235	516	Y>D	No	1000Genomes
ENSVATH12908342	524	K>R	No	1000Genomes
ENSVATH07468595	534	F>L	No	1000Genomes
ENSVATH07468596	549	T>I	No	1000Genomes
ENSVATH12908344	555	I>V	No	1000Genomes
ENSVATH12908355	573	T>K	No	1000Genomes
ENSVATH14645729	663	I>V	No	1000Genomes
ENSVATH00748184	667	D>N	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	Galectin, carbohydrate recognition domain	187 - 401	IPR001079

		Description
EC Number
Subcellular Localization	Golgi apparatus membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
Golgi apparatus	A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane	The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

Name	Definition
carbohydrate binding	Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
galactosyltransferase activity	Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
glycosyltransferase activity	Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
hydroxyproline O-galactosyltransferase activity	Catalysis of the transfer of galactose from UDP-galactose to hydroxyproline residues present in the peptide backbone.

Name	Definition
arabinogalactan protein metabolic process	The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures.
mucilage biosynthetic process involved in seed coat development	The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.
negative regulation of leaf senescence	Any process that stops, prevents or reduces the frequency, rate or extent of leaf senescence.
protein O-linked glycosylation via hydroxyproline	The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q8BG28	B3galnt2	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2	Mus musculus (Mouse)	PR
Q864U6	B3GALNT1	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1	Sus scrofa (Pig)	PR
A7XDQ9	GALT2	Hydroxyproline O-galactosyltransferase GALT2	Arabidopsis thaliana (Mouse-ear cress)	PR
Q8GXG6	GALT4	Hydroxyproline O-galactosyltransferase GALT4	Arabidopsis thaliana (Mouse-ear cress)	PR
Q8L7F9	GALT1	Beta-1,3-galactosyltransferase GALT1	Arabidopsis thaliana (Mouse-ear cress)	PR
Q8RX55	GALT5	Hydroxyproline O-galactosyltransferase GALT5	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9ASW1	GALT3	Hydroxyproline O-galactosyltransferase GALT3	Arabidopsis thaliana (Mouse-ear cress)	PR
Q5XEZ1	HPGT3	Hydroxyproline O-galactosyltransferase HPGT3	Arabidopsis thaliana (Mouse-ear cress)	PR
Q94F27	HPTG1	Hydroxyproline O-galactosyltransferase HPGT1	Arabidopsis thaliana (Mouse-ear cress)	PR
Q6P3P5	b3gnt5	Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
Q5M900	b3galnt2	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR