Q5XEZ1
PR
Gene name |
HPGT3 |
Protein name |
Hydroxyproline O-galactosyltransferase HPGT3 |
Names |
Beta-1,3-galactosyltransferase 9 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G25300 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5XEZ1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5XEZ1-F1 | Predicted | AlphaFoldDB |
48 variants for Q5XEZ1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_2_10774102_A_T | 19 | S>T | No | 1000Genomes | |
| ENSVATH00246515 | 21 | F>S | No | 1000Genomes | |
| tmp_2_10774052_G_T | 35 | F>L | No | 1000Genomes | |
| ENSVATH01892388 | 59 | N>T | No | 1000Genomes | |
| tmp_2_10773750_G_A | 69 | P>L | No | 1000Genomes | |
| ENSVATH01892381 | 71 | V>F | No | 1000Genomes | |
| ENSVATH00246514 | 76 | D>E | No | 1000Genomes | |
| tmp_2_10773715_G_C | 81 | L>V | No | 1000Genomes | |
| ENSVATH01892378 | 85 | D>Y | No | 1000Genomes | |
| ENSVATH05587693 | 88 | R>K | No | 1000Genomes | |
| tmp_2_10773597_C_T | 91 | V>I | No | 1000Genomes | |
| ENSVATH01892377 | 106 | L>F | No | 1000Genomes | |
| ENSVATH01892374 | 109 | L>S | No | 1000Genomes | |
| ENSVATH01892372 | 110 | K>R | No | 1000Genomes | |
| tmp_2_10773530_G_A | 113 | S>L | No | 1000Genomes | |
| ENSVATH14550594 | 114 | S>T | No | 1000Genomes | |
| ENSVATH05587692 | 125 | V>L | No | 1000Genomes | |
| ENSVATH00246513 | 141 | S>T | No | 1000Genomes | |
| ENSVATH01892367 | 142 | Y>* | No | 1000Genomes | |
| ENSVATH01892368 | 142 | Y>C | No | 1000Genomes | |
| ENSVATH05587690 | 146 | G>V | No | 1000Genomes | |
| ENSVATH05587689 | 147 | D>Y | No | 1000Genomes | |
| ENSVATH14550592 | 164 | G>A | No | 1000Genomes | |
| ENSVATH01892359 | 164 | G>S | No | 1000Genomes | |
| ENSVATH01892349 | 188 | L>F | No | 1000Genomes | |
| ENSVATH05587682 | 192 | N>S | No | 1000Genomes | |
| ENSVATH13396734 | 198 | E>D | No | 1000Genomes | |
| ENSVATH01892337 | 201 | A>P | No | 1000Genomes | |
| ENSVATH05587679 | 216 | D>E | No | 1000Genomes | |
| ENSVATH13396732 | 225 | D>N | No | 1000Genomes | |
| tmp_2_10772850_A_C | 229 | L>V | No | 1000Genomes | |
| tmp_2_10772844_G_T | 231 | L>I | No | 1000Genomes | |
| ENSVATH01892335 | 247 | A>S | No | 1000Genomes | |
| tmp_2_10772628_G_T | 259 | A>D | No | 1000Genomes | |
| tmp_2_10772629_C_T | 259 | A>T | No | 1000Genomes | |
| ENSVATH01892332 | 264 | K>Q | No | 1000Genomes | |
| ENSVATH01892330 | 268 | P>A | No | 1000Genomes | |
| ENSVATH01892330 | 268 | P>S | No | 1000Genomes | |
| ENSVATH05587674 | 277 | K>N | No | 1000Genomes | |
| ENSVATH05587668 | 289 | I>R | No | 1000Genomes | |
| tmp_2_10772288_G_C | 290 | L>V | No | 1000Genomes | |
| ENSVATH05587666 | 291 | S>Y | No | 1000Genomes | |
| tmp_2_10772258_T_C | 300 | I>V | No | 1000Genomes | |
| ENSVATH00246502 | 323 | Q>H | No | 1000Genomes | |
| ENSVATH05587662 | 327 | I>L | No | 1000Genomes | |
| ENSVATH05587661 | 327 | I>T | No | 1000Genomes | |
| ENSVATH13396730 | 337 | I>S | No | 1000Genomes | |
| tmp_2_10772023_G_C | 339 | Q>E | No | 1000Genomes |
No associated diseases with Q5XEZ1
1 regional properties for Q5XEZ1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GPCR, rhodopsin-like, 7TM | 53 - 309 | IPR017452 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| galactosyltransferase activity | Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid. |
| glycosyltransferase activity | Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). |
| hydroxyproline O-galactosyltransferase activity | Catalysis of the transfer of galactose from UDP-galactose to hydroxyproline residues present in the peptide backbone. |
| UDP-glycosyltransferase activity | Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| arabinogalactan protein metabolic process | The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures. |
| protein O-linked glycosylation via hydroxyproline | The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline. |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8BG28 | B3galnt2 | UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 | Mus musculus (Mouse) | PR |
| Q8RX55 | GALT5 | Hydroxyproline O-galactosyltransferase GALT5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GXG6 | GALT4 | Hydroxyproline O-galactosyltransferase GALT4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8L7F9 | GALT1 | Beta-1,3-galactosyltransferase GALT1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94F27 | HPTG1 | Hydroxyproline O-galactosyltransferase HPGT1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LV16 | GALT6 | Hydroxyproline O-galactosyltransferase GALT6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| A7XDQ9 | GALT2 | Hydroxyproline O-galactosyltransferase GALT2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ASW1 | GALT3 | Hydroxyproline O-galactosyltransferase GALT3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q6P3P5 | b3gnt5 | Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MESLPTTVPS | KSERRARSSK | FSQSSSKPSV | IMAFFSCVAW | LYVAGRLWQD | AENRVVLNNI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LKKSYDQKPK | VLTVDDKLMV | LGCKDLERRI | VETEMELTLA | KSQGYLKNLK | SGSSSGKKLL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AVIGVYSGFG | SHLRRNTFRG | SYMPQGDALR | KLEERGIVIR | FVIGRSPNRG | DSLDRKIDEE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NQARKDFLIL | ENHEEAQEEL | AKKVKFFFSA | AVQNWDAEFY | IKVDDNIDLD | LEGLIGLLES |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RRGQDAAYIG | CMKSGEVVAE | EGGKWYEPEW | WKFGDEKSYF | RHAAGSLLIL | SKTLAQYVNI |
| 310 | 320 | 330 | 340 | ||
| NSGSLKTYAF | DDTSIGSWMI | GVQATYIDDN | RLCCSSIRQD | KVCSVA |