AiPD: Autoinhibited Protein Database

Gene name	B3galnt2
Protein name	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2
Names	Beta-1,3-GalNAc-T2, Beta-1,3-N-acetylgalactosaminyltransferase II
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:97884
EC number	2.4.1.313: Hexosyltransferases
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

270-345 (Predicted disordered autoinhibitory region) PR

270-345 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8BG28-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs3404219532	146	V>A	No	EVA
rs3404004575	147	V>D	No	EVA
rs3403909316	148	S>N	No	EVA
rs3402506983	172	G>R	No	EVA
rs3404004668	173	F>L	No	EVA
rs3403965971	174	Q>K	No	EVA
rs3403155973	175	R>S	No	EVA
rs3403915799	175	R>T	No	EVA
rs3403676399	179	V>G	No	EVA
rs3389243165	217	L>F	No	EVA
rs3389254959	231	D>V	No	EVA
rs3389268644	238	R>I	No	EVA
rs3389285907	263	P>L	No	EVA
rs3389261670	280	T>I	No	EVA
rs236786614	281	V>I	No	EVA
rs3389237666	337	K>N	No	EVA
rs3389228222	360	D>V	No	EVA
rs3404076153	418	Y>R	No	EVA
rs3389280621	427	W>*	No	EVA
rs3403206861	427	W>C	No	EVA
rs3403904826	428	L>Q	No	EVA
rs3403965992	429	A>P	No	EVA
rs3389200366	432	S>P	No	EVA
rs3389268538	438	Y>F	No	EVA
rs3389268611	504	R>Q	No	EVA

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q8BG28

		Description
EC Number	2.4.1.313	Hexosyltransferases
Subcellular Localization	Golgi apparatus membrane ; Single-pass type II membrane protein Endoplasmic reticulum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
Golgi membrane	The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

Name	Definition
acetylgalactosaminyltransferase activity	Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide.
glycosyltransferase activity	Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
UDP-glycosyltransferase activity	Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule.

Name	Definition
protein glycosylation	A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
protein O-linked glycosylation	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan.
UDP-N-acetylgalactosamine metabolic process	The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q864U6	B3GALNT1	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1	Sus scrofa (Pig)	PR
Q8GXG6	GALT4	Hydroxyproline O-galactosyltransferase GALT4	Arabidopsis thaliana (Mouse-ear cress)	PR
Q8L7F9	GALT1	Beta-1,3-galactosyltransferase GALT1	Arabidopsis thaliana (Mouse-ear cress)	PR
Q8RX55	GALT5	Hydroxyproline O-galactosyltransferase GALT5	Arabidopsis thaliana (Mouse-ear cress)	PR
Q5XEZ1	HPGT3	Hydroxyproline O-galactosyltransferase HPGT3	Arabidopsis thaliana (Mouse-ear cress)	PR
A7XDQ9	GALT2	Hydroxyproline O-galactosyltransferase GALT2	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9ASW1	GALT3	Hydroxyproline O-galactosyltransferase GALT3	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9LV16	GALT6	Hydroxyproline O-galactosyltransferase GALT6	Arabidopsis thaliana (Mouse-ear cress)	PR
Q94F27	HPTG1	Hydroxyproline O-galactosyltransferase HPGT1	Arabidopsis thaliana (Mouse-ear cress)	PR
Q6P3P5	b3gnt5	Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
Q5M900	b3galnt2	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR