Q8L7F9

PR
Gene name
GALT1
Protein name
Beta-1,3-galactosyltransferase GALT1
Names
Beta-1,3-galactosyltransferase 15, Galactosyltransferase 1
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G26810
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

110-191 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8L7F9

Entry ID Method Resolution Chain Position Source
AF-Q8L7F9-F1 Predicted AlphaFoldDB

46 variants for Q8L7F9

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_9289233_G_C 32 P>R No 1000Genomes
ENSVATH04646680 33 Y>F No 1000Genomes
ENSVATH04646679 50 M>R No 1000Genomes
ENSVATH12090354 65 R>T No 1000Genomes
tmp_1_9289095_A_C 78 V>G No 1000Genomes
ENSVATH04646678 80 S>L No 1000Genomes
ENSVATH04646677 82 L>F No 1000Genomes
tmp_1_9289078_C_A 84 V>F No 1000Genomes
tmp_1_9289052_C_G 92 E>D No 1000Genomes
ENSVATH01107591 104 S>I No 1000Genomes
ENSVATH12090352 107 D>V No 1000Genomes
ENSVATH12090353 107 D>Y No 1000Genomes
tmp_1_9288973_T_A 119 I>F No 1000Genomes
tmp_1_9288943_G_A 129 L>F No 1000Genomes
tmp_1_9288709_G_A 207 L>F No 1000Genomes
tmp_1_9288708_A_G 207 L>P No 1000Genomes
ENSVATH13974439 232 P>A No 1000Genomes
ENSVATH00045420 243 Q>L No 1000Genomes
ENSVATH00045419 253 K>N No 1000Genomes
tmp_1_9288447_C_T 264 D>N No 1000Genomes
tmp_1_9288404_C_T 278 R>Q No 1000Genomes
ENSVATH13974438 279 T>I No 1000Genomes
ENSVATH12090346 280 S>F No 1000Genomes
ENSVATH12090314 310 G>S No 1000Genomes
tmp_1_9288218_T_C 340 D>G No 1000Genomes
ENSVATH12090312 351 R>Q No 1000Genomes
tmp_1_9288018_C_A 376 V>F No 1000Genomes
ENSVATH04646675 377 D>N No 1000Genomes
tmp_1_9287982_G_A 388 P>S No 1000Genomes
tmp_1_9287973_G_A 391 P>S No 1000Genomes
tmp_1_9287967_C_T 393 D>N No 1000Genomes
tmp_1_9287888_T_G,C 419 D>A No 1000Genomes
tmp_1_9287888_T_G,C 419 D>G No 1000Genomes
tmp_1_9287850_C_T 432 V>I No 1000Genomes
ENSVATH04646673 438 P>L No 1000Genomes
ENSVATH13974436 464 S>C No 1000Genomes
ENSVATH13974435 470 T>R No 1000Genomes
ENSVATH12090311 474 C>Y No 1000Genomes
ENSVATH12090310 498 D>N No 1000Genomes
tmp_1_9287434_G_A 511 R>C No 1000Genomes
ENSVATH04646671 533 Y>F No 1000Genomes
tmp_1_9287227_A_T 553 Y>N No 1000Genomes
tmp_1_9287221_C_T 555 V>I No 1000Genomes
tmp_1_9287205_G_T 560 A>E No 1000Genomes
ENSVATH13974403 612 G>R No 1000Genomes
tmp_1_9286866_C_T 643 W>* No 1000Genomes

No associated diseases with Q8L7F9

1 regional properties for Q8L7F9

Type Name Position InterPro Accession
domain Galectin, carbohydrate recognition domain 171 - 364 IPR001079

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

3 GO annotations of molecular function

Name Definition
carbohydrate binding Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
glycosyltransferase activity Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
UDP-galactose:N-glycan beta-1,3-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP.

2 GO annotations of biological process

Name Definition
Lewis a epitope biosynthetic process The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides.
protein glycosylation A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.

11 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8BG28 B3galnt2 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 Mus musculus (Mouse) PR
Q864U6 B3GALNT1 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 Sus scrofa (Pig) PR
Q8GXG6 GALT4 Hydroxyproline O-galactosyltransferase GALT4 Arabidopsis thaliana (Mouse-ear cress) PR
Q8RX55 GALT5 Hydroxyproline O-galactosyltransferase GALT5 Arabidopsis thaliana (Mouse-ear cress) PR
Q5XEZ1 HPGT3 Hydroxyproline O-galactosyltransferase HPGT3 Arabidopsis thaliana (Mouse-ear cress) PR
A7XDQ9 GALT2 Hydroxyproline O-galactosyltransferase GALT2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ASW1 GALT3 Hydroxyproline O-galactosyltransferase GALT3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LV16 GALT6 Hydroxyproline O-galactosyltransferase GALT6 Arabidopsis thaliana (Mouse-ear cress) PR
Q94F27 HPTG1 Hydroxyproline O-galactosyltransferase HPGT1 Arabidopsis thaliana (Mouse-ear cress) PR
Q6P3P5 b3gnt5 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q5M900 b3galnt2 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MKRFYGGLLV VSMCMFLTVY RYVDLNTPVE KPYITAAASV VVTPNTTLPM EWLRITLPDF
70 80 90 100 110 120
MKEARNTQEA ISGDDIAVVS GLFVEQNVSK EEREPLLTWN RLESLVDNAQ SLVNGVDAIK
130 140 150 160 170 180
EAGIVWESLV SAVEAKKLVD VNENQTRKGK EELCPQFLSK MNATEADGSS LKLQIPCGLT
190 200 210 220 230 240
QGSSITVIGI PDGLVGSFRI DLTGQPLPGE PDPPIIVHYN VRLLGDKSTE DPVIVQNSWT
250 260 270 280 290 300
ASQDWGAEER CPKFDPDMNK KVDDLDECNK MVGGEINRTS STSLQSNTSR GVPVAREASK
310 320 330 340 350 360
HEKYFPFKQG FLSVATLRVG TEGMQMTVDG KHITSFAFRD TLEPWLVSEI RITGDFRLIS
370 380 390 400 410 420
ILASGLPTSE ESEHVVDLEA LKSPTLSPLR PLDLVIGVFS TANNFKRRMA VRRTWMQYDD
430 440 450 460 470 480
VRSGRVAVRF FVGLHKSPLV NLELWNEART YGDVQLMPFV DYYSLISWKT LAICIFGTEV
490 500 510 520 530 540
DSAKFIMKTD DDAFVRVDEV LLSLSMTNNT RGLIYGLINS DSQPIRNPDS KWYISYEEWP
550 560 570 580 590 600
EEKYPPWAHG PGYIVSRDIA ESVGKLFKEG NLKMFKLEDV AMGIWIAELT KHGLEPHYEN
610 620 630 640
DGRIISDGCK DGYVVAHYQS PAEMTCLWRK YQETKRSLCC REW