Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LFP3

Entry ID Method Resolution Chain Position Source
AF-Q9LFP3-F1 Predicted AlphaFoldDB

37 variants for Q9LFP3

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_3542339_C_T 7 T>M No 1000Genomes
tmp_5_3542345_C_T 9 P>L No 1000Genomes
tmp_5_3542351_T_G 11 L>W No 1000Genomes
tmp_5_3542368_G_T 17 V>F No 1000Genomes
ENSVATH06951889 45 S>L No 1000Genomes
ENSVATH00616532 49 Q>R No 1000Genomes
ENSVATH06951890 53 S>F No 1000Genomes
tmp_5_3542486_G_A 56 R>K No 1000Genomes
ENSVATH10693963 59 P>L No 1000Genomes
tmp_5_3542507_C_A 63 S>* No 1000Genomes
tmp_5_3542540_A_C 74 N>T No 1000Genomes
tmp_5_3542748_G_A 83 E>K No 1000Genomes
ENSVATH10694026 95 G>C No 1000Genomes
ENSVATH10694027 99 A>T No 1000Genomes
ENSVATH06951901 101 A>T No 1000Genomes
ENSVATH06951902 102 A>V No 1000Genomes
ENSVATH13991319 107 G>E No 1000Genomes
ENSVATH00616537 118 T>A No 1000Genomes
tmp_5_3542857_A_C 119 N>T No 1000Genomes
ENSVATH00616538 120 N>S No 1000Genomes
ENSVATH00616539 125 V>F No 1000Genomes
ENSVATH06951903 126 V>I No 1000Genomes
ENSVATH10694028 127 S>F No 1000Genomes
ENSVATH00616540 133 L>F No 1000Genomes
tmp_5_3543744_C_A 185 N>K No 1000Genomes
ENSVATH10694116 235 I>V No 1000Genomes
tmp_5_3543908_C_T 240 P>L No 1000Genomes
tmp_5_3544075_T_G 265 V>G No 1000Genomes
ENSVATH06951924 323 A>S No 1000Genomes
ENSVATH06951925 337 H>Y No 1000Genomes
tmp_5_3544307_C_A 342 D>E No 1000Genomes
tmp_5_3544338_A_C 353 K>Q No 1000Genomes
ENSVATH00616552 389 V>I No 1000Genomes
ENSVATH06951927 429 I>R No 1000Genomes
ENSVATH13991322 430 T>P No 1000Genomes
tmp_5_3544570_C_G 430 T>R No 1000Genomes
tmp_5_3544705_G_T 475 R>L No 1000Genomes

No associated diseases with Q9LFP3

1 regional properties for Q9LFP3

Type Name Position InterPro Accession
domain Exostosin, GT47 domain 146 - 429 IPR040911

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
glycosyltransferase activity Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).

2 GO annotations of biological process

Name Definition
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
protein glycosylation A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.

14 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A5D7I4 EXT1 Exostosin-1 Bos taurus (Bovine) PR
O77783 EXT2 Exostosin-2 Bos taurus (Bovine) PR
Q9Y169 sotv Exostosin-2 Drosophila melanogaster (Fruit fly) PR
Q16394 EXT1 Exostosin-1 Homo sapiens (Human) PR
O43909 EXTL3 Exostosin-like 3 Homo sapiens (Human) PR
P97464 Ext1 Exostosin-1 Mus musculus (Mouse) PR
P70428 Ext2 Exostosin-2 Mus musculus (Mouse) PR
Q9WVL6 Extl3 Exostosin-like 3 Mus musculus (Mouse) PR
Q10SX7 Os03g0107900 Probable glucuronosyltransferase Os03g0107900 Oryza sativa subsp japonica (Rice) PR
O01704 rib-1 Exostosin-1 homolog Caenorhabditis elegans PR
Q94AA9 XGD1 Xylogalacturonan beta-1,3-xylosyltransferase Arabidopsis thaliana (Mouse-ear cress) PR
Q3EAR7 At3g42180 Probable glycosyltransferase At3g42180 Arabidopsis thaliana (Mouse-ear cress) PR
Q5IGR8 ext1a Exostosin-1a Danio rerio (Zebrafish) (Brachydanio rerio) PR
Q5IGR7 ext1b Exostosin-1b Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MADLTCTTPF LLYPSLVIIL FFYSINHHNQ IFSSVVDDDP SCRLSSSPQA VFSSFRIFPF
70 80 90 100 110 120
RSSSSCLNIT SNNNSTSEVV VVEEVDEAVE RIEEGLAMAR AAIRKAGEKN LRRDRDRTNN
130 140 150 160 170 180
SDVGVVSNGS VYLNAFTFHQ SHKEMEKRFK IWTYREGEAP LFHKGPLNNI YAIEGQFMDE
190 200 210 220 230 240
IENGNSRFKA ASPEEATVFY IPVGIVNIIR FVYRPYTSYA RDRLQNIVKD YISLISNRYP
250 260 270 280 290 300
YWNRSRGADH FFLSCHDWAP DVSAVDPELY KHFIRALCNA NSSEGFTPMR DVSLPEINIP
310 320 330 340 350 360
HSQLGFVHTG EPPQNRKLLA FFAGGSHGDV RKILFQHWKE KDKDVLVYEN LPKTMNYTKM
370 380 390 400 410 420
MDKAKFCLCP SGWEVASPRI VESLYSGCVP VIIADYYVLP FSDVLNWKTF SVHIPISKMP
430 440 450 460 470
DIKKILEAIT EEEYLNMQRR VLEVRKHFVI NRPSKPYDML HMIMHSIWLR RLNVRIPLSQ